cleavable

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).

Fmoc-NH-PEG8-CH2CH2COOH (Fmoc-N-amido-PEG8-acid) is a degradable ADC linker for the synthesis of ADC compounds.

Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]

N-Boc-PEG5-bromide is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and serves as a PROTAC linker based on PEG and Alkyl ether.

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

Azido-C6-OH is a cleavable ADC linker utilized for the synthesis of antibody-drug conjugates (ADCs).

DBCO-amine is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-Maleimide (DBCO-MAL) is a non-cleavable ADC linker for the synthesis of ADC compounds.

DBCO-NHS ester is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

DBCO-PEG5-NHS ester is a PROTAC linker belonging to the PEG and Alkyl ether classes for the synthesis of a range of PROTAC molecules.

DBCO-Sulfo-NHS ester sodium is a degradable ADC linker that can be used to synthesize ADC compounds.

m-PEG8-Ms is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC compounds.

PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

TCO-PEG4-NHS ester is a PROTAC linker bridge in the PEG class, used for synthesizing various PROTAC molecules. As a cleavable and synthetic ADC, it is also utilized in the synthesis of antibody-drug conjugates (ADCs).

Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Mal-PEG1-Val-Cit-OH is a cleavable one-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively.

NHS-SS-biotin (Biotin-SS-NHS ester) is a degradable ADC linker used for synthesizing ADC compounds.

SPP is a cleavable linker that can be used to form antibody-coupled compounds with therapeutic effects on cancer.

Sulfo-SNPB is a cleavable linker used in the synthesis of antibody-drug conjugates (ADC).