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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10508 | Asthma relating compound 1 | Others | |
Asthma relating compound 1 is an anti-asthmatic compound. | |||
T8239 | Cromoglicic acid | Others | |
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells. | |||
T9926 | Omalizumab | Others | |
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE) | |||
T2320 | Indacaterol | Adrenergic Receptor | |
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist. | |||
T9448 | IL-17A inhibitor 1 | IL Receptor | |
IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM. | |||
T40423 | L48H37 | ||
L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio... | |||
T16111 | ML604086 | CCR | |
ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations. ML604086 is a selective inhibitor of CCR8. It also inhibiting CCL1 binding to CCR8 on circulating T-cells. | |||
T10425 | AZ084 | CCR | |
AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma. | |||
T9043 | AS1810722 | P450 , STAT | |
AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f... | |||
T17232 | Vidupiprant | AMG 853 | Prostaglandin Receptor |
Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma. | |||
T0211 | Azelastine | Azelastina,Astelin,Azelastinum | SARS-CoV , Histamine Receptor |
Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer. | |||
T5310 | TR-14035 | MDK-1191 | Integrin |
TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM). | |||
T0094 | Budesonide | Entocort,Pulmicort,Rhinocort | Glucocorticoid Receptor |
Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects agai... | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T15017 | CU-T12-9 | TLR | |
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat... | |||
T4503 | Talniflumate | Somalgen | Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger |
Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o... | |||
T1677 | Montelukast | Singular | Leukotriene Receptor , Lipoxygenase , LTR |
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury... | |||
T22358 | Etalocib | LY293111,VML295 | Apoptosis , Leukotriene Receptor , LTR |
Etalocib (LY293111) is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-l... | |||
T1531 | Mometasone furoate | Sch32088 | Glucocorticoid Receptor |
Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for ski... | |||
T6445 | Cilomilast | SB-207499,Ariflo | PDE |
Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3. | |||
T1677L | Montelukast sodium | MK0476 | Leukotriene Receptor , LTR |
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i... | |||
T0211L | Azelastine hydrochloride | Optivar,Azelastine HCl,Allergodil,Astelin | SARS-CoV , Histamine Receptor |
Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity. | |||
T1584 | Terbutaline Sulfate | Terbutaline hemisulfate | Antibacterial , Adrenergic Receptor , Antibiotic |
Terbutaline Sulfate (Terbutaline hemisulfate) is a selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic. | |||
T9962 | Mepolizumab | SB 240563 | IL Receptor |
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis. | |||
T6547 | Ipratropium Bromide | Sch 1000,Itrop,Atrovent | AChR |
Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema. | |||
T1239 | Indacaterol maleate | QAB149 | Adrenergic Receptor |
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist. | |||
T3520 | Setipiprant | KYTH-105,ACT-129968 | GPR , Prostaglandin Receptor |
Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in vari... | |||
T20759 | XRP44X | XRP-44-X,XRP 44X,XRP-44X,XRP 44 X | Ras |
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway. | |||
T3965 | Fevipiprant | QAW039,NVP-QAW039 | GPR , Prostaglandin Receptor |
Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist. | |||
T0098 | Ipratropium bromide monohydrate | Ipratropium bromide hydrate | AChR |
Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial... | |||
T21389 | Enprofylline | Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum | Others |
Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick... | |||
T1127 | Beclometasone dipropionate | Beclovent,Beclomethasone dipropionate,Beconase,Vancenase | Glucocorticoid Receptor |
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone... | |||
T0994 | Ketotifen fumarate | HC 20511 fumarate | PDE , Histamine Receptor |
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. | |||
T0188 | Fluticasone (propionate) | CCI-187881,Fluticasone propionate | Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite |
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist. | |||
T1682 | Methacholine Chloride | Mecholyl chloride,Acetyl-β-methylcholine chloride | AChR |
Methacholine Chloride (Acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower r... | |||
T15543 | IA-Alkyne | N-Hex-5-ynyl-2-iodo-acetamide,Iodoacetamide-alkyne | TRP/TRPV Channel |
IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling. It also has the potential for the study of r... | |||
T2137 | Ibudilast | AV-411,KC-404,MN-166 | PDE |
Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan. | |||
T15259 | Evatanepag | CP-533536 free acid | Prostaglandin Receptor |
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l... | |||
T1083L | Theophylline monohydrate | Quibron | HDAC , PDE , Adenosine Receptor |
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ... | |||
T25465 | GS143 | GS-143,GS 143 | IκB/IKK , E1/E2/E3 Enzyme , NF-κB |
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes and does not inhibit protea... | |||
T10161 | Antiasthmatic Compound 1 | Others | |
Antiasthmatic Compound 1 is an antiasthmatic agent. | |||
T27159 | DF-1111301 | DF-1111301 free | |
DF-1111301, a histamine H1 receptor antagonist, is used potentially for the treatment of asthma. | |||
T13403 | ZK-90055 hydrochloride | ZK 90055 hydrochloride,ZK90055 hydrochloride | Adrenergic Receptor |
ZK-90055 hydrochloride is a β2 adrenergic receptor agonist used to study asthma. | |||
T26524 | ABT-080 | VML530,VML-530,VML 530,ABT080 | Leukotriene Receptor |
ABT-080 (VML 530), a leukotriene synthesis inhibitor, is used potentially for treatment of asthma. | |||
T2270 | Trans-Tranilast | Tranilast trans- | RAAS |
Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993.... | |||
T15715 | LAS101057 | Adenosine Receptor | |
LAS101057 is a novel orally available and potent and selective A2B receptor antagonist for the study of asthma. | |||
T68048 | Cloxacepride | CaMK | |
cloxacepride is a CaM antagonist that is used to treat asthma disease. | |||
T31207 | GSK233705 | Darotropium bromide,GSK 233705,GSK-233705B,GSK233705,GSK233705B,GSK-233705,GSK 233705B | AChR |
GSK233705 (Darotropium bromide) is a muscarinic receptor antagonist used in conjunction with the prevention and treatment of chronic obstructive pulmonary disease (COPD) and asthma in humans. | |||
T22835 | H2L5186303 | ZINC33388081 | LPA Receptor |
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment. | |||
T9816 | Arofylline | LAS 31025 | PDE |
Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1416 | Ayanin | IL Receptor , P450 , PARP , PDE | |
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio... | |||
T3872 | Nodakenin | (+)-Marmesinin | AChE |
Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities. | |||
TN2244 | Sulfuretin | NF-κB , Autophagy | |
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr... | |||
T0480 | Doxofylline | Doxophylline | PDE , Adenosine Receptor |
Doxofylline (Doxophylline) is a methylxanthine derivative with the presence of a dioxolane group in position 7. As a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with s... | |||
T1083 | Theophylline | Theo-24,1,3-Dimethylxanthine | Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy |
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
TQ0185 | 14-Deoxy-11,12-didehydroandrographolide | AP10,14-dehydro Andrographolide | NF-κB |
14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation. | |||
TMA1570 | Sappanone A | NF-κB , Nrf2 | |
Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma. | |||
T1287 | Synephrine | Oxedrine | Endogenous Metabolite , Adrenergic Receptor |
Synephrine (Oxedrine) is sympathetic alpha-adrenergic agonist used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma. | |||
T5311 | Crocin (Gardenia Fruits Extract) | Others | |
Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.). Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects. | |||
T8074 | Esafosfan trisodium | Fosfructose trisodium,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium | Others , Endogenous Metabolite |
Esafosfan trisodium (FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of sickle cell anemia, cardiovascular ischemia and asthma. It acts by stimulating anaerobic glycolysis which gen... | |||
TQ0131 | Rocaglamide | Rocaglamide A,Roc-A | HSP , NF-κB , PERK |
Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells. | |||
T3228 | Fosfructose | D-fructose-1,6-diphosphate,Betulanonaprenol,Diphosphofructose,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan | Others , Endogenous Metabolite |
D-fructose-1,6-diphosphate (D-fructose-1,6-diphosphate), also known as Fosfructose, is a cytoprotective natural sugar phosphate. It functions by promoting anaerobic glycolysis, which generates adenosine triphosphate (ATP... | |||
T0892 | Diphylline | Dyphylline,Diprophylline | PDE , Adenosine Receptor |
Diphylline (Diprophylline) is a xanthine derivative. Diphylline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Diphylline probably acts as a competitive inhibitor of phosphodies... | |||
T3S1612 | Kuwanon G | Moracenin B,Kuwanone G | Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase |
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a... | |||
TN3482 | Bakkenolide B | NOS , COX | |
Bakkenolide B has suppressive properties for allergic and inflammatory responses and may be utilized as a potent agent for the treatment of asthma. | |||
TN2974 | 3-O-Methylquercetin tetraacetate | IL Receptor , TNF , PDE | |
Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3/4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness. | |||
TN1660 | Ganoderic acid C1 | IL Receptor , TNF , NF-κB , MAPK , COX , HIV Protease , DNA/RNA Synthesis | |
Ganoderic acid C1 has anti-inflammatory activity, has potential for treating TNF-α± mediated inflammation in asthma and other inflammatory diseases. Ganoderic acid C1 has anti-tumor-promoting activity. It is moderately a... | |||
TN2517 | 1,7-Dihydroxy-2,3-dimethoxyxanthone | Others | |
1,7-Dihydroxy-2,3-dimethoxyxanthone may have medicinal use in the management of inflammation, asthma and allergy, it antagonises in a non competitive but, reversible manner the contractions induced by chemical inflammato... | |||
TN4819 | (-)-Praeruptorin A | ATPase , IL Receptor , Calcium Channel , P-gp | |
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can ... | |||
T75494 | Shinjulactone M | ||
Shinjulactone M, a quassinoid extracted from the Ailanthus species of the Simaroubaceae family, serves as an antimalarial (febrifuge) and anthelmintic. It is also explored in the study of chronic bronchitis, epilepsy, an... | |||
T82248 | Gymnoside I | ||
Gymnoside I (compound 1), a glycosidoxybenzyl 2-isobutylmalic acid, exhibits antiallergic properties, particularly in the passive cutaneous allergic reaction (PCA) test in mice. It holds potential for research applicatio... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00575 | IL-13 Protein, Human, Recombinant (His) | Human | Human Cells |
Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages... | |||
TMPY-05220 | TSLP Protein, Human, Recombinant (R127A & R130S, His) | Human | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-05453 | TSLP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-02428 | TSLP Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is ... | |||
TMPY-03054 | Fc epsilon RI Protein, Human, Recombinant (His) | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-05084 | Fc epsilon RI Protein, Human, Recombinant | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His) | Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-00849 | ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-00850 | ST2/IL-1 RL1 Protein, Human, Recombinant | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-01359 | ST2/IL-1 RL1 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-04096 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-01871 | IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) | Human | HEK293 |
Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine recept... | |||
TMPY-03102 | IL-18R beta/IL-18RAP Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti... | |||
TMPY-02554 | IL-5 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo... | |||
TMPY-00846 | IL-18BP Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-05576 | IL-5 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo... | |||
TMPY-03198 | IL-12B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts... | |||
TMPY-01111 | IL-18BP Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-01446 | IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding acti... | |||
TMPY-03915 | IL-5 Protein, Human, Recombinant | Human | E. coli |
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo... | |||
TMPY-05492 | IL-18BP Protein, Human, Recombinant (aa 1-192, hFc) | Human | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-01045 | IL-12B Protein, Human, Recombinant (His) | Human | HEK293 |
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts... | |||
TMPY-03516 | IL-12B Protein, Mouse, Recombinant | Mouse | HEK293 |
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts... | |||
TMPY-01870 | IL-9 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates... | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPK-00476 | CD200 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 rece... | |||
TMPK-00733 | CD200 Protein, Mouse, Recombinant (aa 31-232, His) | Mouse | HEK293 |
CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 rece... | |||
TMPY-02574 | Chymase 1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II sys... | |||
TMPJ-00423 | TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of a... | |||
TMPK-01202 | CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated | Human | HEK293 |
CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperrespons... | |||
TMPK-00771 | IL-5 Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k... | |||
TMPK-00772 | IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k... | |||
TMPY-05710 | Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His) | Dermatophagoides pteronyssinus | HEK293 |
Der p 23 is a new major allergen of D. pteronyssinus. The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. Der p 23 may be an essenti... | |||
TMPK-00236 | CEACAM8 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI... | |||
TMPY-03728 | CCL28 Protein, Human, Recombinant (His) | Human | E. coli |
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal su... | |||
TMPK-00021 | IL-5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k... | |||
TMPH-03749 | CYSLTR1 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and... | |||
TMPK-01029 | IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His) | Mouse | HEK293 |
Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disea... | |||
TMPY-01854 | DPP10 Protein, Human, Recombinant (His) | Human | HEK293 |
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w... | |||
TMPK-00149 | Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His) | Human | HEK293 |
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE re... | |||
TMPJ-00542 | TPSB2 Protein, Human, Recombinant (His) | Human | Human Cells |
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites faci... | |||
TMPK-00026 | IL-9 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl... | |||
TMPK-00568 | IL-9 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl... | |||
TMPK-01077 | IGFBP-3R Protein, Human, Recombinant (hFc) | Human | HEK293 |
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFB... | |||
TMPK-01157 | IGFBP-3R Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFB... | |||
TMPY-03877 | ADAM8/CD156a Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been... | |||
TMPK-00025 | IL-9 Protein, Human, Recombinant (hFc) | Human | HEK293 |
IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl... | |||
TMPK-00055 | IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling response... | |||
TMPY-05532 | ADAM8/CD156a Protein, Human, Recombinant (His) | Human | HEK293 |
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been... | |||
TMPJ-00594 | IL-13 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages... | |||
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Cat No. | Product Name | ||
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L2300 | Ion Channel Inhibitor Library | 946 compounds | |
A unique collection of 946 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; | |||
L6140 | Saccharide and Glycoside Natural Product Library | 364 compounds | |
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS; |