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Adagrasib (MRTX849) is an orally active and selective covalent inhibitor of KRAS G12C. Adagrasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Adagrasib exhibits inhibitory activity against KRAS G12C mutant tumors.

ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells

Phorbol 12-myristate 13-acetate (PMA), a member of the phorbol ester group of natural products, activates PKC, SphK, and NF-κB, and induces THP1 cell differentiation.

Isopropyl myristate (IPM) is an ester formed from isopropyl alcohol and myristic acid.

Methyl myristate (methyl tetradecanoate) is a natural product.

Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the inward-rectifier potassium ion channel.

Ethyl Myristate (Ethyl tetradecanoate) is a compound that can be extracted from hops, has moisturizing properties and is commonly used in the skin care industry.

Myristyl Myristate is a lipid molecule that can be used in life science related research. The CAS number of Myristyl Myristate is 3234-85-3.

Sodium metatungstate (Sodium polyoxotungstate) is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase), with Ki values of 2.58 μM for NTPDase 1, 3.26 μM for NTPDase 3, and 28.8 μM for NTPDase 2.

Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.

Sodium tungstate(VI) is a useful organic compound for research related to life sciences and the catalog number is T64775.

Tetrapotassium decatungstate is a useful organic compound for research related to life sciences and the catalog number is T64830.

Sodium myristate is a salt compound frequently used as a surfactant or emulsifier in various industrial applications, including the production of detergents, soaps, and personal care products. Additionally, it serves as an intermediate in synthesizing various organic compounds (including fragrances and pharmaceuticals). Its unique chemical properties make it a key component in numerous industrial processes, particularly in textiles and paper manufacturing.

N-Succinimidyl myristate is a biochemical reagent.

Tetrabutylammonium decatungstate is a useful organic compound for research related to life sciences and the catalog number is T64579.

Ascorbyl myristate is a bioactive chemical.

Oleyl myristate is a bioactive chemical.

Methyl isocostate is a natural product for research related to life sciences. The catalog number is TN4546 and the CAS number is 132342-55-3.

Tetrabutylphonium decatungstate is a useful organic compound for research related to life sciences and the catalog number is T64838.

RMC-6236 is an orally effective and novel triple complex RAS (ON) MULTI inhibitor, which is a potent non covalent inhibitor of multiple RAS variants in GTP binding state. RMC-6236 has anti-tumor activity and can be used in research related to RAS driven tumors. With rich experience in compound synthesis, we can provide fast customized synthesis services for this product according to your research needs.

Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors.

Divarasib (GDC-6036) (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of < 0.01 μM. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibits tumor cell growth. It is being investigated for use in solid tumors, including non-small cell lung and colorectal cancers and other types of cancer.

UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resistance.UC-781 is in a stable state, and is unaffected by lower pH or varying temperatures.

Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity. Ordopidine acts as a dopamine D2 receptor antagonist in vitro and, despite its low affinity, its specific state-dependent behavioral effect characteristics are not generally shared by D2 receptor antagonists.