ampa

Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.

Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.

Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparkinson agent.

Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.

IDRA-21 is a positive AMPA receptor modulator.

NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity. NBQX Disodium is a salt of NBQX. NBQX is a potent and selective AMPA rhodosinate receptor antagonist that can be used to antagonize the excitatory toxicity of glutamate. It has anticonvulsant effects in rodent models.

AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.

(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.

AMPA receptor modulator-2 (Example 134) is an AMPA receptor modulator with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460.

1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of the AMPA-induced current) of 35 μM.

(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.

AMPA receptor antagonist-2 is an AMPA receptor antagonist.

(RS)-AMPA ((±)-AMPA) is a glutamate analog and an agonist of the effective and selective excitatory neurotransmitter L-glutamic acid.

(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analog and serves as an efficient selective agonist for the excitatory neurotransmitter L-glutamic acid (L-glutamic acid). It does not interfere with the binding sites of alginate or NMDA receptors.

AMPA receptor agonist

inactive enantiomer of AMPA

AMPAR agonist

(RS)-AMPA ((±)-AMPA) monohydrate, a potent and selective agonist of the excitatory neurotransmitter L-glutamic acid and a glutamate analogue, does not interact with the binding sites of kainic acid or NMDA receptors, highlighting its selectivity [1] [2].

AMPA receptor antagonist-3 is an AMPA receptor antagonist.

AMPA-IN-1 is a potent inhibitor of AMPA receptors, widely expressed in the brain and central to the regulation of rapid excitatory synaptic transmission and synaptic plasticity. [14]

AMPA Receptor Modulator-4, a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD), serves as an orally active positive allosteric modulator of the AMPA receptors (AMPAR PAMs). This compound is capable of crossing the blood-brain barrier and has been found to enhance cognitive performance and working memory in mice [1].

AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].

AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].

AMPA/kainate antagonist-2 acts as a non-competitive antagonist of AMPA/kainate receptors.