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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7618 | Pyributicarb | TSH-888 | P450 |
Pyributicarb (TSH-888) is a potent activator of both CYP3A4 gene and human pregnane X receptor (hPXR). | |||
TP1022 | Protirelin Acetate | TSH-RF Acetate,TRH Acetate,TRF Acetate | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary. | |||
T80985 | Thyrotropin | Pretiron,TSH | |
Thyrotropin (TSH), a thyroid-stimulating hormone, is synthesized by thyrotrope cells in the anterior pituitary gland and modulates the endocrine activity of the thyroid [1] [2]. | |||
T12073 | ML-109 | TSH Receptor | |
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM) | |||
T12192 | NCGC00229600 | Others , TSH Receptor | |
NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies. | |||
T21383 | D-Thyroxine | Dethyrona,Detyroxin,Dextroid,Dextrothyroxine;Biotirmone,Dextroxin,Biotirmone,Debetrol,Dextrothyroxine | Others |
D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles. | |||
T5383 | D3-βArr | NCGC00379308 | TSH Receptor |
D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation. | |||
T13216 | TSHR antagonist S37 | TSH Receptor | |
TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR). | |||
T38226 | TSHR antagonist S37b | ||
TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1]. | |||
T13217 | TSHR antagonist S37a | Others | |
TSHR antagonist S37a is a selective antagonist of thyrotropin receptor (TSHR), with potential for the treatment of Graves' orbitopathy. | |||
T76727 | Teprotumumab | R 1507,HZN 001 | TSH Receptor , IGF-1R |
Teprotumumab is a human monoclonal antibody that blocks the IGF-1 receptor (IGF-1R). Teprotumumab binds to the extracellular α-subunit domain ligand of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Te... | |||
T24502 | MS437 | MS 437,MS-437 | |
MS437 is a potent TSH receptor agonist. | |||
T24503 | MS438 | MS-438,MS 438 | |
MS438 is an effective agonist of the TSH receptor. | |||
T77258 | Trh-gly | ||
TRH-glycine (TRH-gly) serves as a precursor to thyrotropin-releasing hormone (TRH), capable of inducing the release of thyrotropin (TSH) and prolactin [1]. | |||
T19511 | PGlu-3-methyl-His-Pro-NH2 TFA | A-42872 TFA | Others |
PGlu-3-methyl-His-Pro-NH2 TFA, enhances binding to pituitary TRH receptors and increases stimulation of thyroid-stimulating hormone (TSH) release from the pituitary. | |||
T76496 | Prepro-TRH-(160-169) | ||
Prepro-TRH-(160-169), a connecting peptide of the thyrotropin-releasing hormone prohormone (pro-TRH), enhances TRH-induced thyrotropin (TSH) release [1]. |