carboxylic

CPI-0610 carboxylic acid is an effective and selective small molecule inhibitor of bromine domain and outer end (BET) protein as a ligand of PROTAC target protein. CPI-0610 carboxylic acid may have anticancer and anticancer activities.

(4R)-3-[2-(4-chlorophenoxy)-2-methylpropanoyl]-1,3-thiazolidine-4-carboxylic acid can be used in research in the fields of chemistry and life sciences.

(2S,3AS,7aS)-Octahydroindole-2-carboxylic acid is a valuable organic compound employed in life science research.

Purpurogallin carboxylic acid is a natural product isolated from Macleaya microcarpa (Maxim.) Fedde, has anti-cancer activity.

I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).

(4R,5S)-Nutlin Carboxylic Acid (MDM2 Ligand 2), a Nutlin 3-based MDM2 ligand, can be conjugated to a protein-binding ligand via a linker to create PROTACs[1].

PNU-159682 carboxylic acid is a potent ADCs cytotoxin,PNU-159682 carboxylic acid has protein fold and diverse functions.

4-Androsten-3-one-5-ene-17-carboxylic acid is a derivative of progesterone and functions as a 5α-reductase inhibitor. It prevents the transformation of testosterone into dihydrotestosterone in homogenates of the rat ventral prostate.

amino acid that occurs naturally in the CNS

Alcaftadine is a novel antihistamine for preventing allergic conjunctivitis.

1,3-Dioxolane-2-carboxylic acid, 2-methyl-, (5-nitrofurfurylidene)hydrazide is a bioactive chemical.

Acridan-9-carboxylic acid, 10-methyl-, 2-(diethylamino)ethyl ester, hydrochloride is a biochemical.

Losartan Carboxylic Acid (E-3174), a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), produces a depressor response and vasodilatation. As a metabolite of losartan, it is more potent than losartan in blocking angiotensin II-induced responses in vascular smooth muscle cells.

Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 μM for DPP-4 in human Caco-2 cells. It is formed from hydrolysis of the cyano group on vildagliptin.

JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)

β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not HepG2 or A549 cells (IC50s = 36.41 and 41.51 µg/ml, respectively). It also inhibits cAMP phosphodiesterase with an IC50 value of 96 µM.

1H-Pyrrole-2-carboxylic acid, 4,5-dibromo-1-methyl- (1-methyl-4,5-dibromopyrrole-2-carboxylic acid) is a marine derived natural products found in Agelas flabelliformis.

(R)-Tetrahydrofuran-2-carboxylic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Isothiazole-5-carboxylic acid (8-Isoquinoline-methaneaminedihydrochloride) is an organic compound known for its antibacterial, anticancer, and anti-inflammatory properties. It holds promise in the development of novel compounds to combat various diseases. This compound exhibits a wide range of potential pharmacological activities, aiding in the enhancement of existing inhibitory strategies.

(S)-6-methoxychroman-3-carboxylic acid is a synthetic compound with a molecular formula of C11H10O5. It is a member of the chroman family of compounds, which are characterized by a seven-membered ring with one oxygen and one carbon atom.

5,6-Diaminopyridine-3-carboxylic acid methyl ester (DAPME) has potential applications in anti-tumor, anti-inflammatory, antibacterial and other aspects.

(S)-5-BOC-5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID, with CAS No. 1129634-44-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (S)-5-BOC-5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID, with CAS No. 68947-43-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-METHYL-PIPERIDINE-4-CARBOXYLIC ACID provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE, with CAS No. 71985-80-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.