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N-(acid-PEG10)-N-bis(PEG10-azide)

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Catalog No. TYD-02085Cas No. 2803119-06-2

N-(acid-PEG10)-N-bis(PEG10-azide) is a widely utilized PEG reagent featuring a terminal carboxylic acid and two azide groups. Its hydrophilic PEG spacer enhances solubility in aqueous media. The azide groups can react with alkynes, BCN, or DBCO via Click Chemistry to create stable triazole linkages. The terminal carboxylic acid can form robust amide bonds by reacting with primary amine groups in the presence of activating agents such as EDC or HATU.

N-(acid-PEG10)-N-bis(PEG10-azide)

N-(acid-PEG10)-N-bis(PEG10-azide)

😃Good
Catalog No. TYD-02085Cas No. 2803119-06-2
N-(acid-PEG10)-N-bis(PEG10-azide) is a widely utilized PEG reagent featuring a terminal carboxylic acid and two azide groups. Its hydrophilic PEG spacer enhances solubility in aqueous media. The azide groups can react with alkynes, BCN, or DBCO via Click Chemistry to create stable triazole linkages. The terminal carboxylic acid can form robust amide bonds by reacting with primary amine groups in the presence of activating agents such as EDC or HATU.
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Bioactivity
Description
N-(acid-PEG10)-N-bis(PEG10-azide) is a widely utilized PEG reagent featuring a terminal carboxylic acid and two azide groups. Its hydrophilic PEG spacer enhances solubility in aqueous media. The azide groups can react with alkynes, BCN, or DBCO via Click Chemistry to create stable triazole linkages. The terminal carboxylic acid can form robust amide bonds by reacting with primary amine groups in the presence of activating agents such as EDC or HATU.
Chemical Properties
Molecular Weight1548.8
FormulaC67H133N7O32
Cas No.2803119-06-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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