anti-infection

Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.

2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots, possesses acaricidal properties and can be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl)oxy]acetophenone.

1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products found in boiled beef extracts.

2-Furoic acid (Furan-2-carboxylic acid) reduces serum cholesterol and triglyceride levels and exhibits anti-lipidemic effects.

Sorbic acid is a natural product that inhibits various bacteria, including sporeformers,

Octacosanoic acid has antiplatelet and antithrombotic effects.

3,4,5-Trimethoxybenzaldehyde shows anti-Candida efficacy and inhibits adhesion and biofilms.

Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.

Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.

Pyromeconic acid (3-hydroxy-4H-pyran-4-one) and derivatives thereof are potent inhibitors of endonuclease

2,5-Dihydroxybenzaldehyde (Gentisaldehyde) has antioxidant activity against Mycobacterium avium subsp. Paratuberculosis. 2,5-Dihydroxybenzaldehyde also inhibits S. aureus strains(MIC50: 500 mg L).

Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial activity against Bacillus cereus, S

Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65.

Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells.

(+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.

Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.

2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg disc.

8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.

Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.

Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng mL.

Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol mL.

Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.

2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).

Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.