am-1

Quinabactin(LC-66C6) is a potent sulfonamide abscisic acid ABA agonist.Quinabactin promotes guard cell closure, inhibits water loss, suppresses seed germination, and improves drought tolerance in adult Arabidopsis thaliana and soybean plants.

Ganoderic acid AM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.8+/-0.7 microM.

Carpro-AM1 is a compound that acts as a dual inhibitor of both fatty acid amide hydrolase (FAAH) and substrate-selective cyclooxygenase (COX). It exhibits potent inhibitory activity against FAAH, with an IC50 value of 94 nM [1].

ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin (IC50 = 7 nM) and ICAM-1 (IC50 = 5 nM).

PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.

AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.

AM-1714 is a reasonable selective agonist for the peripheral cannabinoid receptor CB2. In animal studies, it has been shown to have analgesic and anti-abnormal pain effects.

ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.

AM-1638 is an orally active GPR40/FFA1 agonist, useful for studying type II diabetes.

ICAM-1988 is a LFA-1 antagonist.

AM-1430 is a potent and selective PI3Kδ inhibitor. AM-1430 has cellular potency: pAKT IC50 = 0.8 nM; HWB,u (pAKT) IC 50 = 7.7 nM. Rat KLH: IgG ED50 -= 0.016 mg/kg; IhM ED50 = 0.015 mg/kg. Rat PK Clu = 1.7 L/hr/kg.

AM-103 Free Acid is a bio-active chemical.

AM-156 is a bio-active chemical.

AM1488 is a potent, orally active glycine receptor (GlyR) potentiator with an effective concentration (hGlyRα3 EC50) of 0.45 µM [1] [2].

AM-112 is an Oxapenem compound which possesses potent beta-lactamase-inhibitory properties.

TAM-16 is a potent, orally active inhibitor of polyketide synthase 13 (Pks13) with an IC50 value of 0.32 μM, demonstrating promising activity against Mycobacterium tuberculosis. Additionally, TAM-16 inhibits the hERG cardiac ion channel [1] [2].

The Anti-Mouse CD31/PECAM-1 Antibody (390) is an IgG2a, κ antibody inhibitor derived from rats, specifically targeting mouse CD31/PECAM-1.

Anti-Mouse MAdCAM-1 Antibody (MECA-367) is a rat-derived IgG2a, κ antibody inhibitor targeting mouse MAdCAM-1.

Anti-CD54/ICAM-1 Antibody (R6-5-D6) is a chimeric mouse IgG2a antibody that specifically targets human CD54/ICAM-1. The recommended isotype control for this antibody is Mouse IgG2a kappa, Isotype Control.

Anti-Mouse LPAM-1/Integrinα4β7 Antibody (DATK32) is a rat-derived IgG2a, κ antibody inhibitor targeting mouse LPAM-1/Integrinα4β7.

Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) is an IgG1, κ inhibitor antibody derived from rats, specifically targeting mouse CD106/VCAM-1.

Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). Proteasome inhibitor IX shows potent anticancer activity. Proteasome inhibitor IX exhibits HCT116 p53+/+ cells growth inhibitory activity(IC50 = 1.49 μM).

IK-862 is a selective inhibitor of TACE (ADAM17).

INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15.