am-1

ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin (IC50 = 7 nM) and ICAM-1 (IC50 = 5 nM).

PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo. PSNCBAM-1 can be used for obesity studies.

AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.

AM-1714 is a reasonable selective agonist for the peripheral cannabinoid receptor CB2. In animal studies, it has been shown to have analgesic and anti-abnormal pain effects.

ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.

MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 (compound 19-2) serves as a synthetic intermediary for the creation of the drug-linker conjugate, MC-GGFG-AM-(10Me-11F-Camptothecin), utilized in the synthesis of ADCs (Antibody-Drug Conjugates). This intermediate allows for the incorporation of functional groups.

Adrenomedullin (AM) (1-52), human (TFA), is an NH2-terminal truncated adrenomedullin analogue that influences cell proliferation and angiogenesis in cancer.

Adrenomedullin (AM) (1-52), human, is a 52-amino acid peptide that modulates cellular proliferation and angiogenesis in cancer.

AM-1638 is an orally active GPR40 FFA1 agonist, useful for studying type II diabetes.

ICAM-1988 is a LFA-1 antagonist.

AM-1430 is a potent and selective PI3Kδ inhibitor. AM-1430 has cellular potency: pAKT IC50 = 0.8 nM; HWB,u (pAKT) IC 50 = 7.7 nM. Rat KLH: IgG ED50 -= 0.016 mg/kg; IhM ED50 = 0.015 mg/kg. Rat PK Clu = 1.7 L/hr/kg.

AM-103 Free Acid is a bio-active chemical.

AM-156 is a bio-active chemical.

AM1488 is a potent, orally active glycine receptor (GlyR) potentiator with an effective concentration (hGlyRα3 EC50) of 0.45 µM [1] [2].

AM-112 is an Oxapenem compound which possesses potent beta-lactamase-inhibitory properties.

TAM-16 is a potent, orally active inhibitor of polyketide synthase 13 (Pks13) with an IC50 value of 0.32 μM, demonstrating promising activity against Mycobacterium tuberculosis. Additionally, TAM-16 inhibits the hERG cardiac ion channel [1] [2].

Anti-CD54 ICAM-1 Antibody (R6-5-D6) is a chimeric mouse IgG2a antibody that specifically targets human CD54 ICAM-1. The recommended isotype control for this antibody is Mouse IgG2a kappa, Isotype Control.

Anti-Mouse LPAM-1 Integrinα4β7 Antibody (DATK32) is a rat-derived IgG2a, κ antibody inhibitor targeting mouse LPAM-1 Integrinα4β7.

Anti-Mouse CD106 VCAM-1 Antibody (M K-2.7) is an IgG1, κ inhibitor antibody derived from rats, specifically targeting mouse CD106 VCAM-1.

Quinabactin(LC-66C6) is a potent sulfonamide abscisic acid ABA agonist.Quinabactin promotes guard cell closure, inhibits water loss, suppresses seed germination, and improves drought tolerance in adult Arabidopsis thaliana and soybean plants.

D-JNKI-1 (AM-111) is a highly effective, cell-permeable peptide inhibitor.

D-JNKI-1 acetate (AM-111 acetate) is a highly potent and cell-permeable peptide inhibitor of JNK.

IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.

PROTAC IRAK4 degrader-1 (compound I-210) is a Cereblon based PROTAC consisting of the PROTAC IRAK4 ligand-1, the E3 ligase ligand Pomalidomide and the PROTAC linker AM-Imidazole-PA-Boc.