pparγ — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T61417	PPARγ agonist 7
	PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It specifically stimulates adiponectin production in human bone marrow mesenchymal s...
T79678	PPARγ-IN-2		PPAR
	"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes. Furthermore, PPARγ-IN-2 counteracts obesity and associated metabolic syndrome induced by a...		PPAR
T63561	PPARγ agonist 5
	PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.
T61465	PPARγ agonist 3
	PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ. This compound does not exhibit cytotoxicity towards both non-resistant and resistant cells. Notably, PPARγ agonist 3 demonstrates a...
T79182	PPARγ agonist 8		PPAR
	PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator response element (PPRE)-luciferase activity with an effective con...		PPAR
T62581	PPARγ agonist 6
	PPARγ agonist 6 (Compound 12) is a potent agonist of selective PPARγ. PPARγ agonist 6 has potential for cancer disease research.
T61731	PPARγ agonist 4
	PPARγ agonist 4 (Compound 18b), a potent and selective PPARγ agonist, demonstrates antitumor efficacy only when used in conjunction with Imatinib. Notably, PPARγ agonist 4 does not exhibit cytotoxic effects on either non...
T63514	PPARγ agonist 1
	PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects. pparγ agonist 1 has shown research potential in cardiovascular diseases assoc...
T61743	PPARγ agonist 2
	PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ. It exhibits significant potential for utilization in metabolic disease research [1].
T75009	PPARγ/GR modulator 1
	PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits Ki values of 3.3 and 33.6 μM, respectively. This compound is...
T62554	PPARγ phosphorylation inhibitor 1
	PPARγ phosphorylation inhibitor 1 (Compound 10) is a potent PPARγ binding agent (IC50: 24 nM) with antidiabetic effects. PPARγ phosphorylation inhibitor 1 exhibited inhibition of CDK5-mediated PPARγ Ser273 phosphorylatio...
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
TN7060	Methyl oleanonate		PPAR
	3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.		PPAR
T4353	SR-18292	SR 18292	Autophagy
	SR-18292 is an inhibitor of PPAR gamma coactivator-1α (PGC-1α), which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.		Autophagy
T1802	ZLN005		Autophagy
	ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.		Autophagy
T21955	GQ-16		PPAR
	GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.		PPAR
T8763	PTGR2-IN-1	PTGR2-IN-22	Others
	PTGR2-IN-1 is a potent inhibito of PTGR2r(IC50 : 0.7 μM). It increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.		Others
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
T6917	Oleuropein		Apoptosis , Aromatase , ROS , PPAR
	Oleuropein is an antioxidant polyphenol isolated from olive leaf.		Apoptosis , Aromatase , ROS , PPAR