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By Target- PI3K
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Results for "
rp-3
" in TargetMol Product Catalog- Inhibitors & Agonists10
- Peptide Products4
- Recombinant Protein4
- Antibody Products1
RFRP-3(human) TFA
T75866
RFRP-3 (Neuropeptide VF(124-131))(human) TFA, a human homolog of the GnIH peptide, significantly suppresses gonadotropin release through inhibition of Ca2+ mobilization. Acting as an NPFF1 receptor agonist, RFRP-3 (human) also blocks forskolin-stimulated cAMP production with an inhibition concentration (IC50) of 0.7 nM [1].
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RFRP-3 (rat)
T81287420088-80-8
RFRP-3 (rat), a neuropeptide, suppresses gonadotropin release and consequently elevates ghrelin mRNA and circulating growth hormone concentrations [1].
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RFRP-3(human)
RFRP 3 (human)
TP1936311309-27-0
Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.
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RFRP-3, mouse
Neuropeptide NPVF, mouse
TP2977
RFRP-3, mouse is a functional analog of avian Gonadotropin-Inhibitory Hormone (GnIH) that binds to GPR147. It reduces progesterone synthesis by inhibiting FSHR and key steroidogenic enzymes (P450scc, 3β-HSD, StAR). RFRP-3, mouse induces apoptosis by increasing p53 and can inhibit the ERK signaling pathway. Additionally, RFRP-3 is applicable in follicle development research.
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