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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13229 | Tunicamycin | Influenza Virus , Antibacterial , Antibiotic , Antifungal | |
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity... | |||
T9111 | 8-Azaadenosine | Adenosine deaminase | |
8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells. | |||
T9720 | T3Inh-1 | Others | |
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 µM. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic sid... | |||
T2007 | RQ-00203078 | TRP/TRPV Channel | |
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist. | |||
T22115 | SM-7368 | NF-κB | |
The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications. | |||
T9102 | WM-3835 | Apoptosis , Histone Methyltransferase , Histone Acetyltransferase | |
WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation. | |||
TN1019 | Beta-mangostin | β-Mangostin | Apoptosis , Antibacterial , Parasite |
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo... | |||
T14322 | ARP-100 | MMP-2 Inhibitor III | MMP |
ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion ... | |||
T6351 | MGCD-265 analog | MGCD-265,Glesatinib | Apoptosis , VEGFR , c-Met/HGFR |
MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively. | |||
T6496 | Vactosertib | TEW-7197,EW-7197 | ALK , TGF-beta/Smad |
Vactosertib (EW-7197) is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potentia... | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
T5S0045 | Isofraxidin | 6,8-Dimethoxyumbelliferone,Phytodolor | MMP , ERK , p38 MAPK , TLR , COX |
1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote... | |||
T0459 | Sulindac | Arthrocine,MK-231,Clinoril,Sulindac sulfoxide | COX , Autophagy |
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl... | |||
T4S1796 | Heterophyllin B | PI3K | |
Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways and regulating the expression levels of adhesion- and invasion-associa... | |||
T13050 | SYP-5 | HIF/HIF Prolyl-Hydroxylase , HIF | |
SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis. | |||
T25549 | JCP174 | JCP 174,JCP-174 | Serine Protease |
JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1. | |||
TQ0290 | ONO-AE3-208 | AE 3-208 | Prostaglandin Receptor |
ONO-AE3-208 (AE 3-208) is an EP4 antagonist. It suppresses cell migration, invasion, and metastasis of prostate cancer. | |||
T6S0325 | Glycitein | Glycetein | Apoptosis , Others |
1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression. | |||
TN1198 | 19-Hydroxybufalin | Others | |
19-Hydroxybufalin is a natural product, inhibits epithelial-mesenchymal transition and attenuates the migration and invasion of PC3 cells. | |||
TQ0214 | Dimethylcurcumin | ASC-J9,GO-Y025 | Androgen Receptor |
Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion. |