Search Result

Search Results for " atpase "

Targets

229

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T9882	RUVBL1/2 ATPase-IN-1		Others
	RUVBL1/2 ATPase-IN-1 is an effective RUVBL1/2 ATPase inhibitor with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1/2 ATPase-IN-1 can be used in cancer disease studies.		Others
T83967	ATPase-IN-3		ATPase
	ATPase-IN-3 is an ATPase (ATPase) inhibitor that can be used in the study of metabolism-related diseases.		ATPase
T61553	ATPase-IN-2
	ATPase-IN-2 is a compound that acts as an inhibitor of ATPase, with an IC50 value of 0.9 μM. It also inhibits the glycohydrolase activity of C. difficile toxin B (TcdB) with an AC50 value of 30.91 μM. ATPase-IN-2 is comm...
T0712	Suloctidil		ATPase , Platelet aggregation
	Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred.		ATPase , Platelet aggregation
T6443	Chloroprocaine hydrochloride	Chloroprocaine HCl	ATPase , Others
	Chloroprocaine hydrochloride (Chloroprocaine HCl) is a local anesthetic during surgical procedures.		ATPase , Others
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease
T2176	2,3-Butanedione 2-Monoxime	Diacetyl monoxime,2,3-Butanedione-2-monoxime	Akt
	2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.		Akt
T0490	Chlorpropamide	Diabinese	ATPase , ABC
	Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.		ATPase , ABC
T9008	NPD8733		Others
	NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. It specifically binds to valosin-containing protein (VCP)/p97.		Others
T6796	CB-5083	CB5083,CB 5083	p97
	CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).		p97
T3293	Apoptozole	Apoptosis Activator VII	Apoptosis , HSP
	Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.		Apoptosis , HSP
T9230	KM 91104		ATPase
	KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.		ATPase
T2686L	Esomeprazole Sodium	(S)-Omeprazole sodium	ATPase , Proton pump
	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...		ATPase , Proton pump
T9168	NSC 617145	NSC617145,NSC-617145	DNA/RNA Synthesis
	NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.		DNA/RNA Synthesis
T6700	Tenatoprazole	TU-199	Proton pump
	Tenatoprazole (TU-199), a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).		Proton pump
T2621	Rostafuroxin	PST 2238	ATPase , RSV
	Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.		ATPase , RSV
T36816	S-trityl-L-Cysteine	STLC	Kinesin
	S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...		Kinesin
T6953	Prilocaine	Citanest,Propitocaine,NSC 40027	ATPase , Sodium Channel
	Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.		ATPase , Sodium Channel
T1734	Rabeprazole Sulfide	Rabeprazole Related Compound E	Proton pump , Antibacterial
	Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.		Proton pump , Antibacterial
T7144	BTS	N-Tosylbenzylamine,N-Benzyl-p-toluenesulfonamide	ATPase , Myosin
	BTS (N-Tosylbenzylamine) is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 : 5 μM) .		ATPase , Myosin
T10616	BRM/BRG1 ATP Inhibitor-1		Epigenetic Reader Domain
	BRM/BRG1 ATP Inhibitor-1 is an allosteric dual Brahma homolog (BRM)/SWI/SNF related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) and BRG1/SMARCA4 ATPase activity inhibitor (IC50...		Epigenetic Reader Domain
T0796	Prilocaine hydrochloride	Prilocaine HCl,Propitocaine hydrochloride,Xylonest	ATPase , Sodium Channel
	Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.		ATPase , Sodium Channel
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T1651	Rabeprazole sodium	Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium	Apoptosis , Proton pump
	Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. The drug inhibits H(+)-K(+)-exch...		Apoptosis , Proton pump
T8386	Esomeprazole Magnesium trihydrate	(S)-Omeprazole magnesium trihydrate	Proton pump
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...		Proton pump
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T6929	Pantoprazole sodium	Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc	Apoptosis , Others , Proton pump , HIF , Autophagy
	Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...		Apoptosis , Others , Proton pump , HIF , Autophagy
T7540	2,5-Di-tert-butylhydroquinone	BHQ	Calcium Channel , Lipoxygenase , COX
	2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.		Calcium Channel , Lipoxygenase , COX
T27812	Leminoprazole		ATPase
	Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.		ATPase
T22280	BRITE-338733	BRITE338733	ATPase , Antibacterial
	BRITE-338733 is a novel inhibitor of ATPase. BRITE 338733 inhibits the expression of RecA in bacteria with IC50 value of 4.7 μM for the bacterial infections treatment.		ATPase , Antibacterial
T17030	Tegoprazan		ATPase , Proton pump
	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5...		ATPase , Proton pump
T2404	Vonoprazan fumarate	TAK-438	ATPase
	Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.		ATPase
T7134	Mavacamten	MYK-461,SAR439152	Myosin
	Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)		Myosin
T21254	Vonoprazan Fumarate	TAK-438,TAK 438,Vonoprazan Fumurate,TAK438	Proton pump
	Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...		Proton pump
T16865	SCH28080		ATPase , Proton pump
	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhibitor of acid secretion in vivo with anti-ulcer activity, an...		ATPase , Proton pump
T14965	Ciliobrevin D		ATPase , Hedgehog/Smoothened
	Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ...		ATPase , Hedgehog/Smoothened
T17313	(+)-SJ733	SJ000557733	ATPase , Parasite
	(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.		ATPase , Parasite
T12503	(+)-Blebbistatin		Others
	(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.		Others
T27303	Farglitazar	GI-262570,GI 262570,GI262570
	Farglitazar is a PPAR-γ agonist. GI262570 stimulates the ENaC and Na,K-ATPase system resulting in the increasing of water and sodium reabsorption in distal nephron.
T67763	PK095		ATPase
	PK095 is a proprietary compound in the guanidine - based F1F0-ATPase inhibitor family.		ATPase
T10435	Linaprazan	AZD0865	Potassium Channel
	Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.		Potassium Channel
T9553	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid		Others
	8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-car is a H+/K+ ATPase inhibitor with IC50 of 0.38μM.		Others
T13890	SMARCA-BD ligand 1 for Protac dihydrochloride		Epigenetic Reader Domain
	SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.		Epigenetic Reader Domain
T7373	CDN1163		Calcium Channel
	CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).		Calcium Channel
T20436	DHQ	2,3-dihydroxy-quinoxalin	ATPase
	DHQ (2,3-dihydroxy-quinoxalin) is an inducer of ATPase activity that of Herpes Simplex Virus thymidine kinase.		ATPase
T60032	BRM/BRG1 ATP Inhibitor-2		Epigenetic Reader Domain
	BRM/BRG1 ATP Inhibitor-2 is an inhibitor of BRG1/BRM ATPase and can be used in studies about the treatment of BAF-related disorders.		Epigenetic Reader Domain
T13848	SMARCA-BD ligand 1 for Protac		Epigenetic Reader Domain
	SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2		Epigenetic Reader Domain
T9749	FHD-286		Epigenetic Reader Domain
	FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.		Epigenetic Reader Domain
T28136	NC-1300-B	NC 1300 B
	NC-1300-B is a proton pump. H(+)-K(+)-ATPase inhibition with NC-1300-B causes profound renal vasodilation and inhibition of renin release without affecting regulation of GFR.

Compounds

RUVBL1/2 ATPase-IN-1

Target: ATPase, Platelet aggregation

Chloroprocaine hydrochloride

T6443

Synonym: Chloroprocaine HCl

Target: ATPase, Others

Esomeprazole

T20626

Synonym:

Target: Proton pump, Cysteine Protease

2,3-Butanedione 2-Monoxime

T2176

Synonym: Diacetyl monoxime,2,3-Butanedione-2-monoxime

Target: ATPase, ABC

Synonym: CB5083,CB 5083

Target: p97

Apoptozole

T3293

Synonym: Apoptosis Activator VII

Target: Apoptosis, HSP

Synonym: (S)-Omeprazole sodium

Target: ATPase, Proton pump

NSC 617145

T9168

Synonym: NSC617145,NSC-617145

Target: DNA/RNA Synthesis

Target: ATPase, RSV

Synonym: Citanest,Propitocaine,NSC 40027

Target: ATPase, Sodium Channel

Rabeprazole Sulfide

T1734

Synonym: Rabeprazole Related Compound E

Target: Proton pump, Antibacterial

BTS

T7144

Synonym: N-Tosylbenzylamine,N-Benzyl-p-toluenesulfonamide

Target: ATPase, Myosin

BRM/BRG1 ATP Inhibitor-1

T10616

Synonym:

Target: Epigenetic Reader Domain

Prilocaine hydrochloride

T0796

Synonym: Prilocaine HCl,Propitocaine hydrochloride,Xylonest

Target: ATPase, Sodium Channel

Esomeprazole Magnesium

T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

Pantoprazole

T6928

Synonym: SKF96022,BY1023

Target: Apoptosis, Proton pump, Autophagy

Rabeprazole sodium

T1651

Synonym: Dexrabeprazole Sodium,LY307640 sodium,Habeprazole Sodium,Rebeprazole sodium,Aciphex Sodium

Target: Apoptosis, Proton pump

Esomeprazole Magnesium trihydrate

T8386

Synonym: (S)-Omeprazole magnesium trihydrate

Target: Proton pump

Pantoprazole Sodium Hydrate

T0161

Synonym: SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)

Target: Apoptosis, Potassium Channel, Proton pump, Autophagy

Pantoprazole sodium

T6929

Synonym: Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc

Target: Apoptosis, Others, Proton pump, HIF, Autophagy

2,5-Di-tert-butylhydroquinone

T7540

Synonym: BHQ

Target: Calcium Channel, Lipoxygenase, COX

Target: ATPase, Antibacterial

Tegoprazan

T17030

Synonym:

Target: ATPase, Proton pump

Synonym: MYK-461,SAR439152

Target: Myosin

Vonoprazan Fumarate

T21254

Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438

Target: ATPase, Proton pump

Ciliobrevin D

T14965

Synonym:

Target: ATPase, Hedgehog/Smoothened

(+)-SJ733

T17313

Synonym: SJ000557733

Target: ATPase, Parasite

Synonym: GI-262570,GI 262570,GI262570

Target: Potassium Channel

8-[(2,6-dimethylbenzyl)amino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylic acid

T9553

Synonym:

Target: Others

SMARCA-BD ligand 1 for Protac dihydrochloride

T13890

Synonym:

Target: Epigenetic Reader Domain

CDN1163

T7373

Synonym:

Target: Calcium Channel

DHQ

T20436

Synonym: 2,3-dihydroxy-quinoxalin

Target: ATPase

BRM/BRG1 ATP Inhibitor-2

T60032

Synonym:

Target: Epigenetic Reader Domain

SMARCA-BD ligand 1 for Protac

T13848

Synonym:

Target: Epigenetic Reader Domain

FHD-286

T9749

Synonym:

Target: Epigenetic Reader Domain

Cat No.	Product Name	Synonyms	Targets
T1719	Bufalin		ATPase
	Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti...		ATPase
TJP2872	Acevaltrate	Acevaltratum,Acetoxyvaltrate	ATPase , Others
	1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.		ATPase , Others
T0295	Digitoxin	Digitoxoside,Unidigin,Digitoxinum	ATPase , Others
	Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).		ATPase , Others
T5S0890	Oleandrin	Neriostene,Folinerin,Foliandrin	Apoptosis , ATPase , Potassium Channel , Sodium Channel
	1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...		Apoptosis , ATPase , Potassium Channel , Sodium Channel
TN5073	Strophanthidin	Strophanthidine	ATPase , Calcium Channel
	Strophanthidin (Strophanthidine) can induce calcium overload in vivo.		ATPase , Calcium Channel
T2922	Phlorizin	Floridzin,NSC 2833,Phloridzin	ATPase , SGLT
	Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .		ATPase , SGLT
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T6368	Abscisic Acid	Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）	Others , Proton pump , Endogenous Metabolite
	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.		Others , Proton pump , Endogenous Metabolite
T2O2668	Oleic acid	Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid	Apoptosis , ATPase , Others , Endogenous Metabolite
	Oleic acid (Glycon Wo) is a natural product, a common saturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ ATPase activator.		Apoptosis , ATPase , Others , Endogenous Metabolite
T2822	Ginsenoside Rb1	Gypenoside Ⅲ,Gypenoside III	ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV
	Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.		ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV
T6062	Brefeldin A	BFA,Ascotoxin,Cyanein,Decumbin	ATPase , Mitophagy , Antibiotic , Autophagy , HSV , CRISPR/Cas9
	Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation and apoptosis, and also possesses autophagy inhibitory activ...
TN1860	Licoflavone B		ATPase , Anti-infection , Parasite
	Licoflavone B has schistosomicidal activity, it showed high S. mansoni ATPase (IC50 of 23.78 μM) and ADPase (IC50 of 31.50 μM) inhibitory activities.		ATPase , Anti-infection , Parasite
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
T15027	Cyclopiazonic acid		Calcium Channel
	Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA)nanomolar inhibitor and a potent inducer of ce...		Calcium Channel
TQ0184	Chebulinic acid		ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
	Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T3432	Cinobufagin	Cinobufagine	Apoptosis , ATPase , Autophagy
	Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.		Apoptosis , ATPase , Autophagy
T6323	Oligomycin A	MCH 32	ATPase , Antibiotic , Antifungal
	Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria.		ATPase , Antibiotic , Antifungal
T0974	Novobiocin Sodium	Albamycinsodium,Cathomycin,Albamycin	Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
	Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T3926	Echinatin	Retrochalcone	Free radical scavengers
	Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liv...		Free radical scavengers
T6740	Bafilomycin A1		Apoptosis , Proton pump , Antibacterial , Antibiotic , Autophagy
	Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autopha...
T36390	Sodium oleate	Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt	ATPase
	Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na+/K+ ATPase activator.		ATPase
T3868	Agnuside	chasteberry oil	COX , Prostaglandin Receptor , P-gp
	Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at conce...		COX , Prostaglandin Receptor , P-gp
T4897	Inosine-5'-triphosphate trisodium salt	ITP,Inosine 5'-triphosphate trisodium salt	Others , Endogenous Metabolite
	Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substra...		Others , Endogenous Metabolite
TQ0302	Thapsigargin		Apoptosis , SARS-CoV , Calcium Channel
	Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ...		Apoptosis , SARS-CoV , Calcium Channel
T10662L	Calcimycin	Antibiotic A-23187,A-23187	Apoptosis , Antibacterial , Antibiotic , Autophagy , Antifungal
	Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes and uncouples oxidative phosphorylatio...
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
T5079	Adenosine 5'-diphosphate sodium salt	Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others , Endogenous Metabolite
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is...		Others , Endogenous Metabolite
T5075	Phytic acid potassium	Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt	Others , Endogenous Metabolite
	Phytic acid potassium (Inositol polyphosphate dipotassium salt) exists in all eukaryotic cells. In plants, it is known to function as a [PO4]3 storage depot and precursor for other inositol phosphates and pyrophosphates....		Others , Endogenous Metabolite
T6S1049	Wilforine		ATPase
	Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi...		ATPase
T7190	Actein		Apoptosis , Akt , JNK , Autophagy
	Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways in...		Apoptosis , Akt , JNK , Autophagy
T5S1982	Periplocin	Periplocoside	Apoptosis , Others
	1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...		Apoptosis , Others
T13618	Citreoviridin		Others
	Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas, in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-depen...		Others
T14995	Concanamycin A	X 4357B,Antibiotic X 4357B,Concanamycin	Others
	Concanamycin A is a macrolide antibiotic. It also is a specific inhibitor of vacuolar-type H+-ATPase (V-ATPase).		Others
T38609	Mycalolide B
	Mycalolide-B is a marine sponge-derived compound that functions as a selective inhibitor of actomyosin ATPase. It effectively hinders ATP-induced contraction and Mg2+-ATPase activity in the absence of Ca2+.
TN6631	Chamigrenol
	Chamigrenol is a promising candidate for the development of potent Na+/K+ ATPase inhibitors and antimicrobial agents. It inhibited the activities of Na+/K+-ATPase, with the IC50 value of 15.9 ± 0.54 μg/mL.
T10455	Bafilomycin B1		Others
	Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi.		Others
TN4697	Odoroside H		ATPase , Potassium Channel , Sodium Channel
	Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.		ATPase , Potassium Channel , Sodium Channel
T25211	CC 1014	CC1014,CC-1014,NSC-356885,NSC356885,NSC 356885
	CC 1014 is a polypeptide antibiotic isolated from Penicillium lilacinum that inhibits phosphorylation of ADP, Mg ATPase.
TN5141	Thevetin B		ATPase , Potassium Channel , Sodium Channel
	Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.		ATPase , Potassium Channel , Sodium Channel
T16719	Radicicol	Monorden	HSP
	Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and pr...		HSP
T35605	Apoptolidin
	Apoptolidin is an apoptosis inducer originally isolated from Nocardiopsis bacteria. It inhibits the mitochondrial F1FO ATPase (Ki = 4-5 μM). Apoptolidin selectively kills transformed glial cells without significantly aff...
TN5060	Stauntosaponin A		ATPase , Potassium Channel , Sodium Channel
	Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.		ATPase , Potassium Channel , Sodium Channel
T23610	Acerinol
	Acerinol is an active ingredient from traditional Chinese medicinal herbs. It could be used as a cancer multidrug resistance reversal agent. Acerinol can significantly stimulate the activity of ABCB1 ATPase without affec...
T14293	Annonacin		Others
	Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex and it is the active agent found in Graviola leaf extract to act as an inhibitor of sodium/potassium (NKA) and sarco...		Others
TN2306	Wilfordine		ATPase , Potassium Channel , Sodium Channel
	Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.		ATPase , Potassium Channel , Sodium Channel
T27977	Manzamine A	Keramamine A
	Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram nega...
TN3914	Echinatine		ATPase , IL Receptor , TNF
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin c...		ATPase , IL Receptor , TNF
TN3075	5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone		ATPase
	5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell.		ATPase
T38069	Aquastatin A
	Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC...
T72645	Norbatzelladine L
	Norbatzelladine L, an inhibitor of both the catalytic and functional activities of the Pdr5p transporter, suppresses Pdr5p ATPase activity with an IC50 of 3.8 µM. Additionally, it exhibits antifungal, antiparasitic, anti...
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Natural Products

Synonym: Acevaltratum,Acetoxyvaltrate

Target: ATPase, Others

Digitoxin

T0295

Synonym: Digitoxoside,Unidigin,Digitoxinum

Target: ATPase, Others

Oleandrin

T5S0890

Synonym: Neriostene,Folinerin,Foliandrin

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Strophanthidin

TN5073

Synonym: Strophanthidine

Target: ATPase, Calcium Channel

Phlorizin

T2922

Synonym: Floridzin,NSC 2833,Phloridzin

Target: ATPase, SGLT

Deslanoside

T8183

Synonym: Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

Abscisic Acid

T6368

Synonym: Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）

Target: Others, Proton pump, Endogenous Metabolite

Oleic acid

T2O2668

Synonym: Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid

Target: Apoptosis, ATPase, Others, Endogenous Metabolite

Ginsenoside Rb1

T2822

Synonym: Gypenoside Ⅲ,Gypenoside III

Target: ATPase, Mitophagy, IRAK, NF-κB, Autophagy, HSV

Brefeldin A

T6062

Synonym: BFA,Ascotoxin,Cyanein,Decumbin

Target: ATPase, Mitophagy, Antibiotic, Autophagy, HSV, CRISPR/Cas9

Licoflavone B

TN1860

Synonym:

Target: ATPase, Anti-infection, Parasite

Diphyllin

TN1103

Synonym:

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

Cyclopiazonic acid

T15027

Synonym:

Target: Calcium Channel

Chebulinic acid

TQ0184

Synonym:

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

Cinobufagin

T3432

Synonym: Cinobufagine

Target: Apoptosis, ATPase, Autophagy

Oligomycin A

T6323

Synonym: MCH 32

Target: ATPase, Antibiotic, Antifungal

Novobiocin Sodium

T0974

Synonym: Albamycinsodium,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

Echinatin

T3926

Synonym: Retrochalcone

Target: Free radical scavengers

Bafilomycin A1

T6740

Synonym:

Target: Apoptosis, Proton pump, Antibacterial, Antibiotic, Autophagy

Sodium oleate

T36390

Synonym: Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt

Target: ATPase

Agnuside

T3868

Synonym: chasteberry oil

Target: COX, Prostaglandin Receptor, P-gp

Inosine-5'-triphosphate trisodium salt

T4897

Synonym: ITP,Inosine 5'-triphosphate trisodium salt

Target: Others, Endogenous Metabolite

Thapsigargin

TQ0302

Synonym:

Target: Apoptosis, SARS-CoV, Calcium Channel

Calcimycin

T10662L

Synonym: Antibiotic A-23187,A-23187

Target: Apoptosis, Antibacterial, Antibiotic, Autophagy, Antifungal

Paraxanthine

T4973

Synonym: 1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Adenosine 5'-diphosphate sodium salt

T5079

Synonym: Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Phytic acid potassium

T5075

Synonym: Inositol hexakisphosphate dipotassium salt,Phytic acid dipotassium salt,Fytic Acid dipotassium salt,Inositol polyphosphate dipotassium salt

Target: Others, Endogenous Metabolite

Target: Apoptosis, Akt, JNK, Autophagy

Periplocin

T5S1982

Synonym: Periplocoside

Target: Apoptosis, Others

Synonym: X 4357B,Antibiotic X 4357B,Concanamycin

Target: ATPase, Potassium Channel, Sodium Channel

CC 1014

T25211

Synonym: CC1014,CC-1014,NSC-356885,NSC356885,NSC 356885

Target: ATPase, Potassium Channel, Sodium Channel

Target: ATPase, Potassium Channel, Sodium Channel

Target: ATPase, Potassium Channel, Sodium Channel

Manzamine A

T27977

Synonym: Keramamine A

Target: ATPase, IL Receptor, TNF

5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00226	ATPase subunit g Protein, Bovine, Recombinant (His & Myc)	Bovine	E. coli
	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respirator...
TMPJ-01013	VCP Protein, Human, Recombinant (His)	Human	E. coli
	Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxi...
TMPH-01892	ATP4A Protein, Human, Recombinant (His & Myc)	Human	E. coli
	The catalytic subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Uses ATP as an energy source to pump H(+) ions to the gastric ...
TMPY-06599	ATP1B4 Protein, Human, Recombinant (His)	Human	E. coli
	ATP1B4 is a member of the X(+)/potassium ATPases subunit beta family. It is highly expressed in skeletal muscle and at a lower level in heart. ATP1B4 gene can be found in all vertebrate genomes sequenced to date. However...
TMPY-03788	ATP1B1 Protein, Human, Recombinant (His)	Human	HEK293
	ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for es...
TMPY-04927	ATP1B2 Protein, Human, Recombinant (His)	Human	HEK293

TMPH-02059	ATP2A2 Protein, Human, Recombinant (His)	Human	E. coli
	ATP2A2 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02310	ATP6V0D1 Protein, Human, Recombinant (GST)	Human	E. coli
	Subunit of the integral membrane V0 complex of the lysosomal proton-transporting V-type ATPase (v-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providin...
TMPH-01894	ATP4B Protein, Human, Recombinant	Human	E. coli
	The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane...
TMPH-01893	ATP4B Protein, Human, Recombinant (GST)	Human	E. coli
	The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane...
TMPY-04137	ATP6V1F Protein, Human, Recombinant (GST)	Human	E. coli
	ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using revers...
TMPH-00786	BtuD Protein, Halobacterium salinarum, Recombinant (His)	Halobacterium salinarum	E. coli
	Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPH-00787	BtuD Protein, Halobacterium salinarum, Recombinant	Halobacterium salinarum	E. coli
	Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system.
TMPJ-00703	Gankyrin Protein, Human, Recombinant	Human	E. coli
	Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblast...
TMPH-00887	AHSA1 Protein, Human, Recombinant (GST)	Human	E. coli
	Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a re...
TMPY-03263	RUVBL1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family. RUVBL1 is ubiquitously expressed with high expression in heart, skeletal muscle and testis. It poss...
TMPH-00968	ATP5C1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPJ-01179	SWSAP1 Protein, Human, Recombinant (His)	Human	E. coli
	SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD...
TMPH-01711	ABCC1 Protein, Human, Recombinant (His)	Human	E. coli
	Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs a...
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP....
TMPH-03283	CD39 Protein, Rat, Recombinant (His)	Rat	Baculovirus
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP....
TMPY-00541	LON PROTEASE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura...
TMPY-02443	HSP70 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. HSP are abundant and conserved proteins present in all cells. Upo...
TMPH-00594	HtpG Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Molecular chaperone. Has ATPase activity.
TMPH-00595	HtpG Protein, E. coli, Recombinant	E. coli	E. coli
	Molecular chaperone. Has ATPase activity.
TMPH-01024	Calbindin Protein, Human, Recombinant (His)	Human	Yeast
	Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
TMPH-01358	FXYD3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus...
TMPH-02956	TNNI1 Protein, Mouse, Recombinant (Flag & His & Myc)	Mouse	E. coli
	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
TMPH-00307	TnTf Protein, Bovine, Recombinant (His & Myc)	Bovine	E. coli
	Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
TMPJ-00717	BAG2 Protein, Human, Recombinant (His)	Human	E. coli
	BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is...
TMPH-02954	TNNI3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
TMPH-02955	TNNI2 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
TMPJ-00915	HSP40 Protein, Human, Recombinant (His)	Human	E. coli
	DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperon...
TMPY-03612	PSME1 Protein, Human, Recombinant (His)	Human	E. coli
	PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ...
TMPH-01240	MCM2 Protein, Human, Recombinant (His)	Human	E. coli
	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites ...
TMPH-01730	MYBPC3 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATP...
TMPH-01032	Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inh...
TMPY-03614	PSME3 Protein, Human, Recombinant (His)	Human	E. coli
	PSME3, also known as PA28-gamma, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is comp...
TMPH-00741	Rho Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase wh...
TMPH-02133	DDX39B Protein, Human, Recombinant (GST)	Human	E. coli
	Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mR...
TMPH-00583	Rep Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in t...
TMPY-03610	PSME2 Protein, Human, Recombinant (His)	Human	E. coli
	PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ...
TMPH-01731	MYBPC2 Protein, Human, Recombinant (His)	Human	E. coli
	Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATP...
TMPH-00611	DNA helicase II Protein, E. coli, Recombinant	E. coli	E. coli
	A helicase with DNA-dependent ATPase activity. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand. Initiates unwinding more efficiently from a nicked substrate than ds duplex DNA. Involved in th...
TMPH-00612	MutL Protein, E. coli, Recombinant (His)	E. coli	E. coli
	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable co...
TMPJ-00965	TIM16 Protein, S. cerevisiae, Recombinant	S. cerevisiae	E. coli
	Mitochondrial import inner membrane translocase subunit TIM16 (TIM16) is an ssential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membr...
TMPH-00637	RuvA Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a he...
TMPH-01049	Cardiac phospholamban/PLN Protein, Human, Recombinant (GST)	Human	Yeast
	Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stim...
TMPY-03461	GABARAPL2 Protein, Human, Recombinant (His)	Human	E. coli
	GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and...
TMPH-00745	TsaE Protein, E. coli, Recombinant	E. coli	E. coli
	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of thre...
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