rapid

Gentiobiose is a natural oligosaccharide that promotes fruit ripening.

2,4,6-Trimethylphenol (Mesitol), primarily reacting with organic matter (3 DOM*), is a probe compound that undergoes rapid oxidation by singlet oxygen in aqueous solutions.

Isopregnanolone is a pro-sleep progesterone that can interfere with the rapid tolerance of ethanol's anxiolytic effects.

(±)-Anatoxin A fumarate is the salt form of (±)-Anatoxin A.(±)-Anatoxin A is a potent neurotoxic naturally occurring alkaloid known as a rapid death factor (VFDF), a potent, direct, and selective agonist of the nAchR (nicotinic acetylcholine receptor), also known as the nicotinic receptor agonist.

(±)-Anatoxin A hydrochloride is the salt form of (±)-Anatoxin A.(±)-Anatoxin A is a potent neurotoxic naturally occurring alkaloid known as a rapid death factor (VFDF), a potent, direct, and selective agonist of the nAchR (nicotinic acetylcholine receptor), also known as the nicotinic receptor agonist.

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

Ponasterone A is an ecdysteroid with high affinity for the ecdysteroid receptor. It enables rapid switching on and off of reporter genes and is a potent regulator of gene expression in cells and transgenic animals.

Cyanine 3 DBCO chloride is a click chemistry reagent containing a cycloalkyne group. It serves as a linker for the Cyanine5.5 fluorophore. The DBCO group enables copper-free bioorthogonal click reactions with rapid kinetics and good stability (Ex/Em = 550/570 nm).

Cyanine 7 DBCO chloride is a click chemistry reagent containing a cycloalkyne group. Serving as a linker for the Cyanine5.5 fluorophore, the DBCO group enables rapid copper-free, biocompatible click chemistry reactions with good stability [Ex/Em = 745/785 nm].

Cyanine 7.5 DBCO chloride is a click chemistry reagent containing a cycloalkyne group. It serves as a linker for the Cyanine5.5 fluorophore. The DBCO group enhances the copper-free biocompatible click chemistry with rapid reaction kinetics and good stability [Ex/Em = 780/820 nm].

12-oxo Leukotriene B4 (12-Oxo-LTB4) is a potent pro-inflammatory lipid mediator classified as a dihydroxy fatty acid that is enzymatically derived from arachidonic acid metabolism via the 5-lipoxygenase (5-LO) pathway, and it promotes a diverse array of leukocyte functional responses including cellular aggregation, stimulation of transmembrane ion fluxes, enhancement of lysosomal enzyme release, superoxide anion generation, chemotaxis, and chemokinesis; 12-oxo Leukotriene B4 is an initial oxidative metabolite formed from Leukotriene B4 via the LTB4 12-hydroxydehydrogenase pathway, which undergoes rapid enzymatic conversion first to 10,11-dihydro-12-oxo-LTB4 followed by reduction of the 12-oxo group to yield 10,11-dihydro-LTB4, and this metabolite exhibits significantly reduced biological potency, being approximately 70-fold less potent than LTB4 in stimulating Ca2+ mobilization in human neutrophils (EC50 = 33 nM vs. 0.46 nM) and also markedly less effective at stimulating neutrophil migration (EC50 = 170 nM vs. 2.7 nM).

Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatocellular carcinoma cells when used at a concentration of 4 μM.3 1.Qian-Cutrone, J., Huang, S., Shu, Y.-Z., et al.Stephacidin A and B: Two structurally novel, selective inhibitors of the testosterone-dependent prostate LNCaP cellsJ. Am. Chem. Soc.124(49)14556-14557(2002) 2.Wulff, J.E., Herzon, S.B., Siegrist, R., et al.Evidence for the rapid conversion of stephacidin B into the electrophilic monomer avrainvillamide in cell cultureJ. Am. Chem. Soc.129(16)4898-4899(2007) 3.Hu, L., Zhang, T., Liu, D., et al.Notoamide-type alkaloid induced apoptosis and autophagy via a P38/JNK signaling pathway in hepatocellular carcinoma cellsRSC Adv.9(34)19855-19868(2019)

12-OxoETE is an endogenous metabolite formed during the metabolism of arachidonic acid and is present in human platelets and Aplysia nervous tissue .12-KETE induces transient changes and aggregation of intracytoplasmic free calcium ion concentration via leukotriene B4 (LTB4) receptor or coactivation sequences to achieve a rapid and dose-dependent increase.

Clinodiside A in rats with one compartment open model into the body, rapid distribution, elimination rate.

Scopolamine is a high-affinity (nanomolar level) muscarinic receptor antagonist that can reversibly inhibit 5-HT₃ receptor responses (IC₅₀ = 2.09 μM). It is commonly used to induce animal models of Alzheimer's disease or memory impairment.

4-Methylumbelliferyl-β-D-xylopyranoside (4-Methylumbelliferyl-β-D-xyloside) exhibits bursting steady-state kinetics in biological experiments, which supports the conclusion of rapid hydrolysis of the glycosidic bond of the substrate 4-Methylumbelliferyl-β-D-xylopyranoside 4-Methylumbelliferyl-β-D-xylopyranoside can be used for β- xylosidase activity studies.

Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing.

Gibberllin A7 (Gibberllin 7) is important plant growth hormones that promote plant cell growth and elongation. Gebberillins promote rapid stem and root growth, induce mitotic division and initiate (break dormancy) and increase seed germination rates. The gibberellins are also involved in processes such as gravitropism, tensioning and floral display.Gibberellin A3 (G1025, G7645) and A4 (G7276) may be used as supplements to plant growth media such as Murashige and Skoog media. The specific actions of A3 and A4 or combinations of Gebberellins should be determined in specific plant applications.

Creatine monohydrate (Standard) is the analytical standard of Creatine (monohydrate), primarily used for quantitative analysis and metabolic research. Creatine is an endogenous amino acid metabolite synthesized from arginine, glycine, and methionine. It plays a fundamental role in cellular energy metabolism, particularly within tissues with high and fluctuating energy demands like skeletal muscle and the brain. Through the action of creatine kinase (CK), creatine is phosphorylated to phosphocreatine (PCr), serving as a rapid energy buffer to regenerate ATP from ADP, thereby maintaining cellular energy homeostasis during intense activity or metabolic stress.

Isopregnanolone (Standard) is a reference material used for analytical purposes, typically serving as a standard sample for research and analysis of Isopregnanolone.Isopregnanolone is a pro-sleep progesterone that can interfere with the rapid tolerance of ethanol's anxiolytic effects.

Fusaproliferin is a diterpene mycotoxin identified in Fusarium solani. Fusaproliferin can reverse Lipopolysaccharides stimulation and the NF-κB and MAPKs signaling pathways, thus playing a role in anti-inflammatory processes. It has affinity for the TLR4 protein with a KD value of 28.6 μM. Fusaproliferin exhibits cytotoxicity against pancreatic cancer, showing rapid submicromolar IC50 effects.

Tiancimycin A (TNM A) is an anticancer compound that induces rapid DNA damage, cell cycle arrest, and apoptosis. It can be isolated from the Streptomyces genus, specifically strain CB03234.

Artocarpin is a flavonoid isolated from the wood of Artocarpus heterophyllus with bactericidal activity, inhibiting multidrug-resistant Staphylococcus aureus and Enterococcus spp. Artocarpin inhibits melanin biosynthesis in B16 melanoma cells and induces rapid cell lysis. Artocarpin is used in the study of skin diseases.

Meranzin hydrate exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α±-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors; it produces a rapid effect mediated by AMPA