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Search Results for " brd "

20

Compounds

Cat No. Product Name Synonyms Targets
T25175 BRD 9757 BRD9757,N-Hydroxy-1-cyclopentene-1-carboxamide,BRD-9757 HDAC
BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) is a selective inhibitor of HDAC6 (IC50 = 30 nM).
T10602L BRD 4354 HDAC
BRD 4354 is an inhibitor of HDAC5 and HDAC9. For HDAC5 and HDAC9, the IC50s values are 0.85 and 1.88 μM, respectively.
T10603 BRD-6929 HIV Protease , HDAC
BRD-6929 is a selective, brain-penetrant HDAC1 and HDAC2 inhibitor (IC50:  1 and 8 nM). BRD-6929 (Cpd-60) shows high-affinity to HDAC1 and HDAC2 (Kis: 0.2 and 1.5 nM) [2]. BRD-6929 potentiates the efficacy of gnidimacrin...
T26894 BRD0209 BRD-0209,BRD 0209 GSK-3
BRD0209 is a highly selective and potent GSK3 inhibitor.
T30577 BRD0418 BRD 0418,BRD-0418 Others
BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.
T26901 BRD-9526 BRD 9526
BRD-9526 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T23820 BRD32048 BRD-32048,BRD 32048 DNA/RNA Synthesis
BRD32048 is the ETV1 transcription factor oncoprotein inhibitor.
T2292 FPH2 BRD-9424 Others
FPH2 (BRD-9424) (BRD-9424) is a small molecule promoting differentiation of iPS-derived hepatocytes.
T6506 FPH1 BRD-6125 Others
FPH1 (BRD-6125) (BRD-6125) can promote the expansion of iPS-derived hepatocytes.
T35872 BRD-8000.3
BRD-8000.3 is a narrow-spectrum, bactericidal antimycobacterial agent known for its specific inhibition of EfpA. It exhibits potent activity against wild-type strains and proves to be a valuable tool in tuberculosis rese...
T10602 BRD 4354 ditrifluoroacetate BRD 4354 ditrifluoroacetate (315698-07-8 free base) HDAC
BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
T70600 BRD-7880
BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.
T10605 BRD-K98645985 Others
BRD-K98645985 is a BAF transcriptional repression inhibitor (EC50: ~2.37 µM). It binds ARID1A-specific BAF complexes, potently reverses HIV-1 latency and prevents nucleosomal positioning.
T69692 BRD-K25923209
BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.
T2102 FH1 BRD-K4477,NSC 12407 Others
FH1 (NSC-12407) (BRD-K4477), a small molecule, enhances the functions of hepatocytes and promotes differentiation hepatocytes derived by iPS.
T41198 BRD PHOTAC-I-3
BRD PHOTAC-I-3 is a photoswitchable BET bromodomain degrader (PHOTAC, PHOtochemically TArgeting Chimera). BRD PHOTAC-I-3 comprises a ligand for an E3 ligase, a photoswitch, and the BET bromodomain targeting ligand (+)-JQ...
T16905 SNIPER(BRD)-1 Others
SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway an...
T10604 BRD-IN-3 Others
BRD-IN-3 is a highly potent PCAF bromodomain (BRD) inhibitor (IC50: 7 nM). It also exhibits activity against GCN5 and FALZ.
T61361 BRD-8899
BRD-8899 is a STK33 inhibitor, with an IC 50 of 11 nM [1].
T2353 BRD7116 BRD7716 DNA gyrase , Antibacterial
BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.
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