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HCV

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    306
    TargetMol | Inhibitors_Agonists
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    19
    TargetMol | Peptide_Products
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    1
    TargetMol | Inhibitory_Antibodies
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    TargetMol | PROTAC
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    26
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    TargetMol | Recombinant_Protein
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    TargetMol | Inhibitors_Agonists
Uprifosbuvir
MK-3682, MK3682, MK 3682, IDX-21437, IDX21437, IDX 21437
T290691496551-77-9In house
Uprifosbuvir (MK-3682) is a uridine nucleoside monophosphate prodrug inhibitor of hepatitis C virus NS5B RNA polymerase with antiviral activity for the study of chronic hepatitis C virus.
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6-8 weeks
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Ribavirin
Tribavirin, RTCA, NSC-163039, ICN-1229
T068436791-04-5
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
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Mizoribine
NSC 289637, HE 69, Bredinin
T118850924-49-7
Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.
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Deferiprone
Deferidone, CP20
T156530652-11-0
Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.
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Honokiol
NSC 293100
T300135354-74-6
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1 ERK2.
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2′-O-Methylcytidine
T382372140-72-9
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G., Tomassini, J.E., Carroll, S.S., et al.Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitroJ. Bio. Chem.278(49)49164-49170(2003)
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TargetMol | Inhibitor Sale
Resiquimod
S28463, R848
T6964144875-48-9
Resiquimod (R848) is a Toll-like receptor 7 8 (TLR7 TLR8) agonist that induces cytokine upregulation. Resiquimod is an immunomodulator with antitumor and antiviral activity.
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Ombitasvir
ABT-267
T71581258226-87-7
Ombitasvir (ABT-267) is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a
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EIDD-1931
Beta-d-N4-hydroxycytidine
T84983258-02-4
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity that inhibits the replication of severe acute respiratory syndrome coronavirus [SARS-CoV] in Vero 76 cells, Middle East respiratory syndrome coronavirus [MERS-CoV] in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s = 0.1, 0.15, and 0.3 μM, respectively).
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Tizoxanide
TIZ, Desacetyl-nitazoxanide
T2279173903-47-4
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
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TargetMol | Inhibitor Sale
Glecaprevir
ABT-493
T51261365970-03-1
Glecaprevir (ABT-493) is an HCV NS3 4A protease inhibitor, (IC50s: 3.5-11.3 nM).
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Mulberroside C
T5S1598102841-43-0
1. Mulberroside C has antioxidant activity.
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Telaprevir
VX-950, MP-424, LY-570310, Incivek
T6190402957-28-2
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
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Platycodin D3
TN208967884-03-1
Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced splenocyte proliferation in the OVA-immunized mice. Platycodin D3 also exerts anti-Hepatitis C virus (HCV) activity.
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Syrosingopine
TN225284-36-6
Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux. Syrosingopine is an orally available antihypertensive drug with potential for cancer research in combination with metformin.
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PSI-6206
RO 2433, GS-331007, 2'-deoxy-2'-fluoro-2'-C-methyluridine
T2117863329-66-2
PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.
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Azvudine
RO-0622, FNC
T144891011529-10-4
Azvudine (FNC) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine inhibits NRTI-resistant viral strains. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).
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Myriocin
Thermozymocidin, ISP-I
T1616535891-70-4
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour growth by regulating macrophage polarisation and function through the PI3K Akt mTOR pathway.Myriocin inhibits HCV infection and can be used in the study of neurological diseases. Myriocin inhibits HCV infection and can be used to study neuropathy and fungal infections.
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7-10 days
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GSK-A1
T274991416334-69-4
GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.
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Pseudane IX
2-nonyl-4-hydroxyquinoline, 2-nonyl-4(1h)-quinolone, 2-nonyl-1H-quinolin-4-one
T3837555396-45-7
Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg ml.
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Oglufanide
L-Glutamyl-L-tryptophan, H-Glu-Trp-OH
T720338101-59-6
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator that inhibits vascular endothelial growth factor (VEGF).
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NM107
NM-107, 2'-C-Methylcytidine
T721520724-73-6
NM107 (2'-C-Methylcytidine) is a ribonucleoside with broad-spectrum antiviral activity and acts as a nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, demonstrating an EC50 of 1.85 μM in wild-type replicon cells.
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PSI-6130
R 1656
T7607817204-33-4
PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.
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HCV-IN-29
T115391009119-83-8
HCV-IN-29 is an inhibitor of the hepatitis C virus (HCV).
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