T14328 |
AS2521780
|
1214726-89-2
|
98%
|
|
AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).
|
T16526 |
Phorbol 12,13-dibutyrate
|
37558-16-0
|
98%
|
|
Phorbol 12,13-dibutyrate is a PKC activator. It also is a potent skin tumor promoter.
|
TN4431 |
Leucosceptoside A
|
83529-62-8
|
98%
|
|
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidas...
|
T16848 |
SB-218078
|
135897-06-2
|
98%
|
|
SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM). SB-218078 is a potent, ATP-competitive, and cell-permeable checkpoint kinase 1 i...
|
T35328 |
H-1152 dihydrochloride
|
871543-07-6
|
98%
|
|
|
TN4300 |
Isojacareubin
|
50597-93-8
|
98%
|
|
Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standa...
|
T3689 |
Ruboxistaurin hydrochloride
|
169939-93-9
|
98%
|
|
Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sele...
|
T10888 |
CRT0066854 hydrochloride
|
2250019-91-9
|
98%
|
|
CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 valu...
|
T13605 |
Cercosporin
|
35082-49-6
|
98%
|
|
Cercosporin is produced by a plant pathogen, Cercosporakikuchii, and the elsinochromes. Cercosporin is a potent photosensitizer with a short activation wavelengt...
|
T15637 |
K-252b
|
99570-78-2
|
98%
|
|
K-252b is an indolocarbazole isolated from the actinomycete Nocardiopsis and is a PKC inhibitor. K-252b can be used to inhibit extracellular kinases of cells in ...
|
T15638 |
K-252c
|
85753-43-1
|
98%
|
|
K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 µM). K-252c also inhibits β-lactamase, chymotry...
|
T5423 |
PKC-theta inhibitor
|
736048-65-0
|
98%
|
|
PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.
|
TN2799 |
20-Deoxyingenol 3-angelate
|
75567-38-3
|
98%
|
|
20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant pl...
|
TN2326 |
(Z)-Butylidenephthalide
|
72917-31-8
|
98%
|
|
(Z)-Butylidenephthalide has antitumor effect, can effectively inhibit the tumor growth in the glioma.
|
TN3655 |
Cimiside E
|
154822-57-8
|
98%
|
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
|
TN1542 |
Cycloheterophyllin
|
36545-53-6
|
98%
|
|
Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced oxidative stress and damage, and could be u...
|
TN3517 |
Bisacurone
|
120681-81-4
|
98%
|
|
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi...
|
T1606 |
Fasudil
|
103745-39-7
|
98%
|
|
Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
|
TN4114 |
Gardenin A
|
21187-73-5
|
98%
|
|
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
|
T4001 |
Euxanthone
|
529-61-3
|
98%
|
|
Euxanthone has vasorelaxation effect, may be through multiple pathways involved PKC-mediated signal pathway and calcium-independent pathway, it induces its vasod...
|