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Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels

Msr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function.

CIK4, an optimized cage-like electrophilic probe, significantly enhances the coverage of intracellular cysteine residues. It serves as a valuable tool for studying changes in cysteine reactivity and PTMs (post-translational modifications).

Wheat germ agglutinin-AF350 (WGA-AF350) is a plant lectin conjugated with the fluorescent dye AF350, utilized for identifying carbohydrate chains. It serves as a tool for assessing abnormal glycosylation levels in vivo. The specific glycosylation detection sites of Wheat germ agglutinin are bis-GlcNAc and SA.

BP Fluor 594 NHS ester is a widely used tool for modifying proteins or antibodies through the labeling of primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling process is optimal at pH 7-9, forming stable covalent amide bonds. BP Fluor 594 dye supports high molar ratio protein labeling with negligible self-quenching, resulting in brighter conjugates and more sensitive detection. BP Fluor 594 is a bright, water-soluble, pH-insensitive red fluorescent dye effective across a pH range of 4 to 10, with absorption and emission peaks at 590 and 617 nm, respectively. It is compatible with 561 nm and 594 nm laser lines. BP Fluor 594 can bind to various antibodies, peptides, proteins, tracers, and amplification substrates, and it is commonly used to generate stable signals in imaging and flow cytometry.

BP Fluor 488 Azide is a versatile dye. This dye serves as a crucial tool in biological experiments, aiding researchers in observing and analyzing cellular structures, tracking biomolecules, assessing cellular functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications span from basic scientific research to clinical diagnostics. Additionally, dyes like BP Fluor 488 Azide are widely used in traditional areas such as textile dyeing and emerging fields including functional textile processing, food coloring, and dye-sensitized solar cells.

(γ-AmNS)UTP (trisodium) is a fluorescent derivative of UTP utilized for monitoring RNA polymerase activity. Upon RNA incorporation, UMP releases γ-AmNS-PPi, which exhibits higher intrinsic fluorescence than (γ-AmNS)UTP. Additionally, (γ-AmNS)UTP (trisodium) serves as a tool in the research of antimicrobial and antitubercular agents.

Hoechst 33258 trihydrochloride (Bisbenzimide) is a benzimidazole anti-filarial agent. it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication. it also interferes with mitosis.

Coumberone is a metabolic fluorogenic probe and isoform-selective substrate for all AKR1C isoforms. It can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone is a valuable tool for researching AKR1C.

TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exceptional reactivity, generality, stability, and usability, TFMU-ADPr is an effective tool for evaluating small-molecule inhibitors and investigating the regulation of ADP-ribosyl catabolic enzymes in vitro [1].

DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite, a dye reagent for oligonucleotide labeling, serves as a pivotal tool in RNA therapeutic research, RNA aptamer development, and ribozyme studies aimed at RNA structure elucidation. This compound offers broad utility as a probe for uncovering RNA structure complexities. For optimal preservation, it should be stored away from light.

3-MeOARh-NTR is an activatable imaging probe characterized by high selectivity and stability, offering a high signal-to-noise ratio specifically for nitroreductase (NTR) detection. It serves as an efficient molecular tool for identifying endogenous NTR [1].

GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1].

IR-990, an activatable NIR-II fluorescent probe featuring an acceptor-π-acceptor (A-π-A) structure, enables real-time in vivo detection of hydrogen peroxide (H2O2). It serves as an effective diagnostic tool for drug-induced liver injury (DILI) [1].

C12 NBD Galactosylceramide, a fluorescent dye-labeled variant of galactosylceramide, possesses a C12 nitrobenzoxadiazole (C12 NBD) moiety that enables fluorescence. This compound serves as a tool in imaging research [1].

BODIPY 630/650X is a fluorescently labeled conjugate of the adenosine receptor ligand N-ethylcarboxamido-adenosine (NECA), which exhibits distinct excitation and emission maxima at approximately 630 nanometers and 650 nanometers, respectively, making it a valuable tool for fluorescence-based assays and imaging studies targeting adenosine receptor activity and distribution.

Biotin-PEG-Alk (MW 2000) is a biotin-labeled polyethylene glycol (PEG) derivative with an alkyne group for click chemistry applications. This compound efficiently binds to biotin targets via the alkyne moiety, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAC) and enhancing biotin-avidin interaction assays in bioconjugation processes like protein labeling. The hydrophilic nature of PEG ensures solubility in aqueous environments and minimal toxicity.

Ziptide, a peptide substrate, is recognized by several serine threonine protein kinases, such as MAPK activated protein kinase 2 (MAPKAPK2), MAPKAPK3, MAPKAPK5, checkpoint kinase 1 (Chk1), AMP-activated protein kinase (AMPK), and calcium calmodulin-dependent protein kinase II (CamKII). It serves as a tool in evaluating CamKII activity for the development of inhibitors.

4-Carboxy-pennsylvania green, a versatile dye, serves as a critical tool in various biological experiments. Its uses extend to observing and analyzing cell structures, tracking biomolecules, evaluating cell functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. The applications of this dye span from basic scientific research to a broad spectrum of clinical diagnostics. Additionally, it is extensively employed in traditional industries like textile dyeing and emerging sectors including functional textile processing, food pigments, and dye-sensitized solar cells.

5(6)-Carboxy-eosin, a multifunctional dye, serves as a crucial tool across various scientific, clinical, and industrial applications. In biological experiments, this dye enables researchers to observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish between cell types, detect biomolecules, study tissue pathology, and monitor microorganisms. Its utility extends beyond basic research to encompass a broad spectrum of diagnostics. Additionally, 5(6)-Carboxy-eosin finds extensive use in traditional sectors like textile dyeing and in innovative areas such as functional textile processing, food pigments, and dye-sensitized solar cells.

5MP-Fluorescein (compound 3e), a fluorescein dye derived from 5-Methylene pyrrolone (5MP), exemplifies a bioconjugation tool that is both highly thiol-specific and can be removed without a trace [1].

Acid Red 266 is a multifunctional dye utilized in various fields. It serves as a crucial tool in biological experiments by aiding researchers in observing and analyzing cell structures, tracking biomolecules, evaluating cell functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications extend from basic scientific research to a broad spectrum of clinical diagnostics. Additionally, Acid Red 266 is widely employed in traditional sectors like textile dyeing, as well as in emerging areas such as functional textile processing, food pigments, and dye-sensitized solar cells.

Alkyne cyanine dye 718 serves as a versatile tool across multiple scientific and industrial applications. This dye is pivotal in biological experiments, aiding in the observation and analysis of cellular structures, tracking biomolecules, evaluating cell functions, differentiating cell types, and studying tissue pathology. Its uses extend beyond basic research to include clinical diagnostics, ensuring broad utility in both traditional domains like textile dyeing and innovative areas such as functional textile processing, food coloring, and dye-sensitized solar cells.

Alkyne MegaStokes dye 735 serves as a versatile tool in both traditional and emerging fields. This multifunctional dye is crucial in biological experiments, facilitating the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, differentiation of cell types, detection of biomolecules, investigation of tissue pathology, and monitoring of microorganisms. Its applications extend from basic research to a broad spectrum of clinical diagnostics. Beyond its scientific uses, Alkyne MegaStokes dye 735 is also prevalent in conventional textile dyeing, functional textile processing, food pigments, and dye-sensitized solar cells.