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Search Result

Search Results for " llc "

18

Compounds

8

Natural Products

5

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T32810 LL-C 10037alpha LLC 10037alpha,LL-c10037alpha
LL-C 10037alpha is a gamma-aminoepoxysemiquinone isolated from Streptomyces.
T12580 PTUPB COX , Epoxide Hydrolase
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).
T0463 Loxoprofen Loxoprofene,Loxoprofeno,Koloxo COX
Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.
T9616 PD-1/PD-L1-IN-10 PD-1/PD-L1
PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.
T6835 Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526 Dopamine Receptor
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
T39195 YM-244769 dihydrochloride Calcium Channel
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys.
T9888 YM-244769 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]- Calcium Channel
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effec...
T11719 JMV 2959 hydrochloride (925238-89-7 free base) JMV 2959 hydrochloride GHSR
JMV 2959 hydrochloride (925238-89-7 free base) is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
T78975 IDO1-IN-22 Indoleamine 2,3-Dioxygenase (IDO)
IDO1-IN-22 (Compound 3) is an inhibitor of IDO1, demonstrating potent activity with biochemical hIDO1 IC50 of 67.4 nM and HeLa hIDO1 IC50 of 17.6 nM. It exhibits excellent antitumor efficacy in an LLC xenograft model and...
T38281 C22 Galactosylceramide (d18:1/22:0)
C22 Galactosylceramide is a sphingolipid that has been found in the central nervous system.1,2C22 Galactosylceramide levels are increased in the spinal cord, but not the brain or liver, of mice fed a methionine-restricte...
T38286 C26 Sphingomyelin (d18:1/26:0) C26 Sphingomyelin (d18:1/26:0)
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory co...
T37455 C18 D-threo Ceramide (d18:1/18:0) C18 D-threo Ceramide (d18:1/18:0)
C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2[Matreya, LLC. Catalog No. 1855] 1.Koola...
T36695 TAS-103
TAS-103 is a dual inhibitor of DNA topoisomerase I/II, used for cancer research. TAS-103 is a dual inhibitor of DNA topoisomerase I/II. TAS-103 (0.1-10 μM) is active on CCRF-CEM cells, with an IC50 value of 5 nM. TAS-103...
T36974 D-threo-PPMP hydrochloride
D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a ...
T37953 Sphingomyelins (buttermilk)
Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes.1SMs make up 2-15% of the total organ phospholipid population but are found at higher concentrations in the brain and myelin sheaths surr...
T35854 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a r...
T37187 D-erythro/L-threo Lysosphingomyelin (d18:1) D-erythro/L-threo Lysosphingomyelin (d18:1)
Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins.1,2It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis...
T37582 Ganglioside GM1 Mixture (ovine) (ammonium salt)
Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched i...
Cat No. Product Name Synonyms Targets
T5S0106 Peimisine Ebeiensine RAAS , AChR
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...
TN1040 Skullcapflavone II COX , Antibacterial , TGF-beta/Smad
Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of al...
TN5033 Skullcapflavone I IL Receptor , Caspase , Prostaglandin Receptor
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep...
T3S1967 (S)-Indoximod N-ME-Tryptophan,Abrine,L-Abrine Others , Indoleamine 2,3-Dioxygenase (IDO)
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...
TN4455 Lucialdehyde B Integrase , HSV
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
TN4457 Lucidal Others
Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.
T35483 19,20-Epoxycytochalasin D
19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for...
TN4108 Ganoderic acid Z Antifection
The binding affinities of ganoderic acid DM and ganoderic acid Z (ΔGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential s...

Natural Products

Peimisine
T5S0106
Synonym: Ebeiensine
Target: RAAS, AChR
Skullcapflavone II
TN1040
Synonym:
Target: COX, Antibacterial, TGF-beta/Smad
Skullcapflavone I
TN5033
Synonym:
Target: IL Receptor, Caspase, Prostaglandin Receptor
(S)-Indoximod
T3S1967
Synonym: N-ME-Tryptophan,Abrine,L-Abrine
Target: Others, Indoleamine 2,3-Dioxygenase (IDO)
Lucialdehyde B
TN4455
Synonym:
Target: Integrase, HSV
Lucidal
TN4457
Synonym:
Target: Others
19,20-Epoxycytochalasin D
T35483
Synonym:
Target:
Ganoderic acid Z
TN4108
Synonym:
Target: Antifection

Recombinant Proteins

Species：
Human (4)
Rat (1)
Expression System：
HEK293 (3)
E. coli (1)
Yeast (1)
Tag：
His (4)
mFc (1)
Cat No. Product Name Species Expression System
TMPY-03397 TPPP3 Protein, Human, Recombinant (His) Human E. coli
TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons...
TMPY-00326 Bikunin/AMBP Protein, Human, Recombinant (mFc) Human HEK293
The AMBP [A1M (alpha1-microglobulin)/bikunin precursor] gene encodes two plasma glycoproteins: A1M, an immunosuppressive lipocalin, and bikunin, a member of plasma serine proteinase inhibitor family with prototypical Kun...
TMPY-00363 Bikunin/AMBP Protein, Human, Recombinant (aa 206-348, His) Human Yeast
The AMBP [A1M (alpha1-microglobulin)/bikunin precursor] gene encodes two plasma glycoproteins: A1M, an immunosuppressive lipocalin, and bikunin, a member of plasma serine proteinase inhibitor family with prototypical Kun...
TMPY-03044 Bikunin/AMBP Protein, Human, Recombinant (aa 1-203, His) Human HEK293
The AMBP [A1M (alpha1-microglobulin)/bikunin precursor] gene encodes two plasma glycoproteins: A1M, an immunosuppressive lipocalin, and bikunin, a member of plasma serine proteinase inhibitor family with prototypical Kun...
TMPY-00161 Bikunin/AMBP Protein, Rat, Recombinant (His) Rat HEK293
The AMBP [A1M (alpha1-microglobulin)/bikunin precursor] gene encodes two plasma glycoproteins: A1M, an immunosuppressive lipocalin, and bikunin, a member of plasma serine proteinase inhibitor family with prototypical Kun...
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