st2

Expression system: HEK293 Cells
Length: 1-328, Full Length
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-328, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-328, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-332, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-332, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-328, Full Length
Activity: ELISA

sST2 Protein, Human, Recombinant is expressed in E. coli.

Expression system: HEK293 Cells
Length: 27-337 (mutation), Full Length of Mature Protein
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 27-337, Full Length of Mature Protein
Activity: ELISA

Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.

ST2 IL-1 RL1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.1 kDa and the accession number is XP_005575214.1.

Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8 MARCH8 and the cargo receptor.

Expression system: E. coli
Length: 1-126, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 52-151, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 49-160, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 49-160, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 52-151, Partial
Activity: Not Tested

Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1 ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.