p 40

Anti-Mouse IL-12 p40 Antibody (8D12.N) is a monoclonal antibody targeting mouse IL-12 p40. It can be used for cytokine signaling and immune modulation research.

Anti-Mouse IL-12p40 Antibody (C17.8) is a rat-derived IgG2a, κ inhibitor targeting mouse IL-12p40.

Anapoe-NID-P40 is a useful organic compound for research related to life sciences. The catalog number is TF0003 and the CAS number is 2497-59-8.

CGP 40215 is a specific S-adenosylmethionine decarboxylase (AdoMetDC) inhibitor that was found to inhibit the growth of Leishmania donovani promastigotes

ASP-4058 is a selective, safe, and orally active second-generation agonist of sphingosine phosphate receptors 1 and 5 (S1P1 and S1P5).ASP-4058 ameliorates experimental autoimmune encephalomyelitis in mice.

CEP-40125 (RXDX-107) is a DNA alkylating agent used for researching advanced solid tumors.

PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.

(R)-MMP-408 is an isomer of MMP-408, which is an effective MMP-12 inhibitor with an IC₅₀ of 2 nM against human MMP-12. (R)-MMP 408 can influence the epithelial-mesenchymal transition (EMT) process in nasal epithelial cells and is suitable for use in research on chronic obstructive pulmonary disease (COPD) and chronic sinusitis.

Laromustine (VNP40101M) is a sulfonyl hydrolytic alkylating prodrug used in cancer therapy with significant anticancer activity. Inhibiting thioredoxin reductase can be used to study acute myeloid leukemia.

CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).

CP-409092 hydrochloride, a partial agonist of the GABAA receptor, exhibits anti-anxiety activity.

CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.

Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.

Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).

MMP408 acts as an inhibitor of MMP-12.

RP-4029 is a selective covalent inhibitor of hPolθ, exhibiting an IC50 of 0.013 nM for hPolθ and 6.6 nM for mPolθ. It is applicable in the study of cancers with homologous recombination (HR) deficiencies.

KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).

Hexamide is a protein inhibitor.

LP-403812 is a potent inhibitor of the proline transporter.

RXP 407 is a selective inhibitor of the N-domain of angiotensin I-converting enzyme. RXP 407 blocks the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis in vivo.

AMP-404 is a biochemical.

ASP-4000 HCl is an inhibitor of dipeptidyl peptidase 4 (DPP) with anti-hyperglycemic activity.

P-4010 is effective against herpes simplex.

Casimersen (SRP-4045) is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer class that binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame through exon 45 skipping. Casimersen enables the production of an internally truncated yet functional dystrophin protein, thereby serving as a specialized molecular tool for studying exon-skipping mechanisms and therapeutic development in Duchenne muscular dystrophy research.