p 40

Anti-Mouse IL-12p40 Antibody (C17.8) is a rat-derived IgG2a, κ inhibitor targeting mouse IL-12p40.

Anapoe-NID-P40 is a useful organic compound for research related to life sciences. The catalog number is TF0003 and the CAS number is 2497-59-8.

CGP 40215 is a specific S-adenosylmethionine decarboxylase (AdoMetDC) inhibitor that was found to inhibit the growth of Leishmania donovani promastigotes

ASP-4058 is a selective, safe, and orally active second-generation agonist of sphingosine phosphate receptors 1 and 5 (S1P1 and S1P5).ASP-4058 ameliorates experimental autoimmune encephalomyelitis in mice.

CEP-40125 (RXDX-107) is a DNA alkylating agent used for researching advanced solid tumors.

PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.

MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.

Laromustine (VNP40101M) is a sulfonyl hydrolytic alkylating prodrug used in cancer therapy with significant anticancer activity. Inhibiting thioredoxin reductase can be used to study acute myeloid leukemia.

CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).

CP-409092 hydrochloride, a partial agonist of the GABAA receptor, exhibits anti-anxiety activity.

CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.

Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.

Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).

MMP408 acts as an inhibitor of MMP-12.

KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).

Hexamide is a protein inhibitor.

LP-403812 is a potent inhibitor of the proline transporter.

RXP 407 is a selective inhibitor of the N-domain of angiotensin I-converting enzyme. RXP 407 blocks the degradation of hemoregulatory peptide acetyl-Ser-Asp-Lys-Pro with no effect on angiotensin I hydrolysis in vivo.

AMP-404 is a biochemical.

ASP-4000 HCl is an inhibitor of dipeptidyl peptidase 4 (DPP) with anti-hyperglycemic activity.

P-4010 is effective against herpes simplex.

Casimersen (SRP-4045) is an antisense oligonucleotide in the phosphorodiamidate morpholino oligomer subclass. It binds to exon 45 of dystrophin pre-mRNA, skipping the exon to restore the open-reading frame, resulting in a functional but internally truncated dystrophin protein. Casimersen is used in Duchenne muscular dystrophy (DMD) research.

Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) designed to selectively bind to exon 53 of dystrophin pre-mRNA, used in the investigation of Duchenne muscular dystrophy (DMD).

ASP-4058 hydrochloride is a selective, orally active secondary agonist of sphingosine phosphate receptors 1 and 5 (S1P1 and S1P5). ASP-4058 hydrochloride is safe and improves experimental autoimmune encephalomyelitis in mice.