humans

Pitavastatin lactone is the major metabolite of Pitavastatin in humans.Pitavastatin is a competitive inhibitor of HMG-CoA reductase.

BQ-788 is a selective and potent ETB receptor antagonist with potential hypertensive activity.BQ-788 inhibits ET-1 binding to ETB receptors and inhibits exogenous ET-1-induced elevation of coronary artery perfusion pressure.

LEQ506 is a Smo inhibitor with IC50s of 2 nM and 4 nM for hSmo and mSmo, respectively.

Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.

Human Serum Albumin (HSA) is the most abundant protein in human plasma, is produced in the liver and is water soluble, with a molecular weight of 66.5 kDa. HSA inhibits Alzheimer's disease by selectively binding to cross-structured A oligomers. HSA is a key endogenous inhibitor of amyloid-β (Αβ) aggregation. HSA is used as a carrier protein in cell culture for the transport of fatty acids, steroids, and thyroid hormones and to regulate osmolality of the blood, and is also used in drug delivery studies, immunoassays, and cell freezing. cell freezing.

Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).

Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).

CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR) alpha. CUDA may be valuable for the study of cardiovascular diseases.

The ED50 of J-2156 in rats for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws was 3.7 and 8.0 mg/kg, respectively. J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC5

KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 for the treatment of diabete.

Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors and reduces neurotransmission in the central nervous system and is used in the study of migraines and for pain relief.

MK-4256 is an effective and selective SSTR3 antagonist (IC50s: 0.66 nM and 0.36 nM in human and mouse receptor binding assays, respectively).

Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin is used for central nervous system disorders such as Alzheimer;s disease, schizophrenia and cognitive disorders.

Human Serum Albumin-RBITC (HSA-RBITC) is a biomaterial or organic compound suitable for life science research.

Secretin (28-54), human TFA is a 27-amino acid peptide that acts on the human Secretin receptor.

Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.

Human Serum Albumin-Cy3 is a human serum albumin conjugated with Cy3 (Ex=554 nm; Em=568 nm). It serves as a fluorescent marker for labeling or detecting specific antigens, molecules, or cellular structures.

Human Serum Albumin-AF647 (HSA-AF647) is a biochemical reagent employed as a biomaterial or organic compound in life science research.

Human Serum Albumin-AF488 is a biochemical reagent conjugated with the fluorophore AF488 (Ex=488 nm; Em=496 nm). It is utilized for labeling or detecting specific antigens, molecules, or cellular structures.

Human Serum Albumin-Biotin is Human Serum Albumin (HSA) labeled with Biotin.

Human Serum Albumin-Cy5 is a Cy5-labeled Human Serum Albumin (HAS).

Type II collagen (from human sternal cartilage) is a collagen protein used to stimulate the animal immune system to produce specific antibodies against it. This collagen also serves as a hydrolytic substrate for MMP (matrix metalloproteinases).

α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase, ptyalin), is a biomaterial or organic compound utilized for research in the life sciences.

Creatine Kinase MM (CK-MM), Human Skeletal Muscle (CK-MM, CKMM), serves as a biomaterial or organic compound applicable in life science research.