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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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    TargetMol | Inhibitors_Agonists
L-161982
T15681147776-06-5In house
L-161982 is a selective EP4 receptor antagonist that inhibits PGE2-induced ERK phosphorylation and cell proliferation in HCA-7 cells and alleviates collagen-induced arthritis in mice.
  • $68
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Dasatinib
BMS-354825
T1448302962-49-8
Dasatinib (BMS-354825) is an orally active, ATP-competitive tyrosine kinase inhibitor that targets Src and Bcr-Abl (Ki=16 30 pM), with antitumor activity, used in the treatment of leukemia and lymphoma.
  • $37
In Stock
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Dasatinib monohydrate
BMS-354825 Monohydrate
T1448L863127-77-9
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
  • $33
In Stock
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D-Tagatose
d-tagatos, D-(-)-Tagatose
T472387-81-0
D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose and isomer of D-galactose, occurs naturally in Sterculia setigera gum and is found in small quantities in various foods such as sterilized and powdered cow's milk, hot cocoa, and various cheeses, yogurts, and other dairy products. It can be synthesized from D-galactose by isomerization under alkaline conditions in the presence of calcium. D-Tagatose has numerous health benefits, including promotion of weight loss, no glycemic effect, anti-plaque, non-cariogenic, anti-halitosis, prebiotic, and anti-biofilm properties; it is beneficial for organ transplants, enhancement of flavor, improvement of pregnancy and fetal development, treatment of obesity, and reduction in symptoms associated with type 2 diabetes, hyperglycemia, anemia, and hemophilia. (PMID: 17492284).
  • $29
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Pinostilbene
T375542438-89-1
Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA.
  • $30
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TargetMol | Inhibitor Sale
K-Ras-IN-1
T546984783-01-7
K-Ras-IN-1, a K-Ras inhibitor, is characterized by its chemical formula C20H19ClN4O2S and is also known as N-[(1S)-3-cyclopropyl-1-[(6-fluoro-1H-benzimidazol-2-yl)sulfanyl]-2-oxo-1-(phenylmethyl)propyl]-4-fluorobenzenesulfonamide (compound [18, dashboard 819041] in brackets).
  • $45
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AMG 487
T10297L473719-41-4
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
  • $46
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Glyco-Obeticholic acid
T11428863239-60-5
Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).
  • $179
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Tauro-Obeticholic acid
T13092863239-61-6
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
  • $119
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Barasertib
AZD1152
T14371722543-31-9
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
  • $42
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PTC-209
PTC209, PTC 209
T2345315704-66-6
PTC-209 is a potent and selective BMI-1 inhibitor.
  • $47
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PF-04217903
T2676956905-27-4
MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity.
  • $35
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PHPS1
PHPS-1, PHPS 1
T28410314291-83-3
PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.
  • $39
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Indole-3-pyruvic acid
3-(3-Indolyl)-2-oxopropanoic acid
T4939392-12-1
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmental changes.
  • $41
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Ganoderic acid D
T5S1133108340-60-9
1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.
  • $39
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PTC-209 hydrobromide
PTC-209 HBr
T61781217022-63-3
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
  • $31
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NMS-E973
T66091253584-84-7
NMS-E973 is a potent and selective Hsp90 inhibitor with a DC50 of less than 10 nM for Hsp90 binding, displaying no activity against a panel of 52 diverse protein kinases.
  • $35
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1,3,5,8-Tetrahydroxyxanthone
Desmethylbellidifolin
TN10842980-32-7
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta, exhibiting antispasmodic and anti-inflammatory activities. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method and significantly inhibits the growth of Staphylococcus aureus at a dose of 200 µg/disk.
  • $89
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Hamamelitannin
TN1722469-32-9
Hamamelitannin has cytotoxic, and antibiofilm activities. It increases the susceptibility of S. aureus to antibiotic treatment in in vivo Caenorhabditis elegans and mouse mammary gland infection models. It also has a high protective activity on cell damag
  • $98
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Acolonifloroside K
T1245266251-64-5
Acolonifloroside K is a useful organic compound for research related to life sciences. The catalog number is T124526 and the CAS number is 6251-64-5.
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Curcolone
T125611
Curcolone is a useful organic compound for research related to life sciences and the catalog number is T125611.
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1-Bromopinacolone
T718025469-26-1
1-Bromopinacolone is an active site-directed covalent inhibitor for acetylcholinesterase
  • $1,520
6-8 weeks
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Hydroxypinacolone Retinoate
T84262893412-73-2
Hydroxypinacolone Retinoate (HPR) is a retinoid commonly added to skin care products and can be used to study skin aging and acne.
  • $32
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Curcolonol
TN3731217817-09-9
Curcolonol is a natural product of Curcuma, Zingiberaceae. The catalog number is TN3731 and the CAS number is 217817-09-9. Curcolonol can be used as a reference standard.
  • $760
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