c 14

G0-C14 HCl is the salt form of G0-C14, a cationic lipid molecule and amphiphilic dendritic macromolecule commonly used in the synthesis of nanoparticles and vaccine delivery.

Pomalidomide-5-C14-NH2 hydrochloride is based on pomalidomide and acts as an E3 ubiquitin ligase cereblon (CRBN) ligand, which is utilized to recruit cereblon proteins. It can attach to protein ligands through a linker to form PROTAC.

N-(3-Oxotetradecanoyl)-DL-homoserine lactone, part of the N-Acyl homoserine lactone (AHL) family derived from gram-negative bacteria, serves as a quorum sensing (QS) signaling molecule.

G0-C14 is a cationic lipid-like molecule commonly used for synthesizing nanoparticles and vaccine delivery.

Thalidomide-5-O-C14-NH2 hydrochloride, a cereblon ligand based on Thalidomide, facilitates the recruitment of CRBN protein. By incorporating a linker, this compound can be conjugated to a ligand to create PROTACs [1].

Thalidomide-4-O-C14-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, through the attachment of a linker, can be utilized to create PROTACs [1].

IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. It effectively extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells at concentrations of 0.05 and 0.5%. Furthermore, IMCTA-C14 demonstrates antibacterial activity against various bacterial strains (MICs = 8-128 µg/ml) and shows cytotoxicity against a spectrum of 52 cancer cell lines (IC50s = 2.9-29.2 µg/ml). At a concentration of 50 µM, it induces autophagy in OVK18 cells.

C14-4 (C14-494) is an ionizable lipid nanoparticle used for delivering CAR mRNA to primary human T cells.

Sphingomyelin (d18:1,C14:0) is a principal sphingolipid found in mammalian cells that enhances the molecular order of cell membranes.

C14 dihydroceramide (d18:0/14:0) (Standard) is a reference standard of C14 dihydroceramide (d18:0/14:0) intended for quantitative analysis, quality control, and related biochemical research applications.

C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).

C14 Glucosyl(β) ceramide (d18:1/14:0) is a β-glucosylceramide.

C14 Galactosyl(β) ceramide (d18:1/14:0) is a β-galactosylceramide.

C14:1 L-Carnitine chloride is an acylcarnitine lipid.

CB1 receptor inverse agonist

Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA), effectively suppressing the metastasis-promoting effect of ITPKA in lung tumor cells (with IC50 of 37 μM in ADP-Glo Assay).

Orotic acid-6-C14 is an endogenous metabolite. [PubChem]

Tipranavir C-14 is an antiretroviral protease inhibitor primarily used for the treatment and prevention of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS).

C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research.

C14-A1 is an ionizable cationic lipid utilized in the synthesis of lipid nanoparticles (LNP), which are employed for delivering mRNA and various other payloads.

C14-O2 is an ionizable cationic lipid utilized in the synthesis of lipid nanoparticles (LNP) for the delivery of mRNA and other payloads.

N-3-oxo-tetradecanoyl-L-Homoserine lactone (3-oxo-C14-HSL) is a small diffusible acylhomoserine lactone signaling molecule that functions in bacterial quorum sensing by coordinating LuxIR-family transcriptional regulators in response to cell density, appears later than shorter-chain AHLs during biofilm development, stimulates putisolvin production, and ultimately inhibits biofilm formation, N-3-oxo-tetradecanoyl-L-Homoserine lactone provides a critical molecular tool for studying bacterial communication, metabolism, and anti-virulence strategies.

N-tetradecanoyl-L-homoserine lactone is a long-chain N-acyl homoserine lactone (AHL) and bacterial quorum sensing signal molecule that promotes diatom growth and upregulates genes involved in intracellular signalling.