bam

BAM (8-22) acetate is a proteolytically cleaved product of proenkephalin A. BAM (8-22) acetate activates Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner.

Endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM); first isolated from bovine adrenal medulla. Unlike BAM 22P , does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors.

BAM 22P acetate is a potent opioid agonist.

Bam 12P is a Pro-Met-enkephalin precursor that is isolated from the bovine adrenal medulla.

Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.

Bam 12P acetate is the putative enkephalin precursor in bovine adrenal, pituitary, and hypothalamus.

BAM(8-22) TFA, a proteolytically cleaved fragment of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), specifically MrgprC11 and hMrgprX1, inducing scratching in mice via an Mrgpr-dependent pathway [1].

tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate (catalog number: T64912, CAS number: 6926-09-6) is a valuable organic compound for life sciences research.

(S)-tert-Butyl (1-hydroxy-4-methylpentan-2-yl)carbamate is a useful organic compound for research related to life sciences. The catalog number is T66221 and the CAS number is 82010-31-9.

(S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate is a useful organic compound for research related to life sciences. The catalog number is T66458 and the CAS number is 1676-86-4.

(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66476 and the CAS number is 623950-02-7.

2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid is a valuable organic compound for life sciences research [Catalog No. T66529, CAS No. 1289942-66-0].

Methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate is a valuable organic compound for life sciences research (catalog number: T66530, CAS number: 1332524-01-2).

Coibamide A, an N-methyl-stabilized cytotoxic depsipeptide, exhibits potent antiproliferative activity, induces autophagosome accumulation via an mTOR-independent mechanism, and triggers apoptosis. Furthermore, it inhibits VEGFA/VEGFR2 expression, effectively suppressing tumor growth in glioblastoma xenografts [1] [2].

Bamadutide (SAR425899) is a potent dual agonist for the glucagon-like peptide-1 receptor and glucagon receptor, enhancing β-cell function and reducing glucose absorption in vivo, thereby improving postprandial glucose control. This compound has potential applications in type 2 diabetes research [1].

Lead-bamzireotide navoxetan is an antitumor compound that can be labeled with 121Pb for tumor targeting.

Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).

PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).

GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.

β-Amyloid (25-35) is a fragment of the Alzheimer’s amyloid beta peptide Aβ(25-35), exhibiting neurotoxic effects and commonly used to establish both cellular and animal models of Alzheimer’s disease.

Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicity. Davunetide acetate possesses neuroprotective, neurotrophic, and cognitive protective properties.

β-Amyloid (1-42), rat/mouse TFA is a 42-amino-acid polypeptide fragment that exhibits neurotoxicity to hippocampal slices and is commonly used to establish Alzheimer's disease models for related research.

β-Amyloid (1-37) (human) is potentially associated with mental status in Alzheimer's disease.

The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.