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Search Results for " gated "

Targets

166

Compounds

13

Natural Products

38

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T22408 Proflavine 3,6-Diaminoacridine Antibacterial
Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings.
T19723 AMTB hydrochloride AMTB TRP/TRPV Channel
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...
T15260 Evenamide NW-3509 Sodium Channel
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
T0939 Phenytoin Diphenylhydantoin,5,5-Diphenylhydantoin Virus Protease , Sodium Channel
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor...
T0438 Proflavine Hemisulfate 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate Others , Potassium Channel , DNA , Thrombin , Antibacterial , Autophagy
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and a...
T4497 Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine Others
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...
T2535 Ivabradine hydrochloride S 16257-2,Ivabradine HCl Adrenergic Receptor
Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat...
T0008 Phenytoin sodium 5,5-Diphenylhydantoin sodium salt,Diphantoine,Dilantin sodium,Diphenylhydantoin Sodium Virus Protease , Sodium Channel
Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .
T7806 Licarbazepine ​10,11-hydroxy-10,11 Dihydrocarbamezer Others
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.
T8333 Aurintricarboxylic acid ATA,NSC-4056,NSC4056,NSC 4056 Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
T7516 ZD7288 ICI D7288 HCN Channel
ZD7288 (ICI D7288), a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity.
T11990 Meclofenamic acid Meclofenamate Others , Gap Junction Protein
Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities.
T35854 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a r...
T37270 9(E),11(E)-12-nitro Conjugated Linoleic Acid
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combinat...
T19988 Conjugated Estrogen sodium Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39
Conjugated estrogens are medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estr...
T21009 Conjugated linoleic acid
Conjugated linoleic acid, a naturally occurring fatty acid, is present in ruminant meat and dairy products and is produced by a bio-hydrogenation process in the rumen. In this case, the predominant isomer formed is 9cis,...
T74877 GalNAc unconjugated/naked Fitusiran
GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran i...
T74876 GalNAc unconjugated/naked Inclisiran
GalNAc unconjugated/naked Inclisiran is a double-stranded small interfering RNA (siRNA) without GalNAc conjugation. GalNAc unconjugated/naked Inclisiran inhibits the transcription of PCSK-9 , and can be used for hyperlip...
T80249 Epsilon-V1-2, Cys-conjugated PKC
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur...
T12424 PF-06305591 PF-6305591 Others
PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM).
T77711 Calcium Channel antagonist 4 Calcium Channel
Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).
T77712 Calcium Channel antagonist 3 Calcium Channel
Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).
T31716 Etidocaine Hydrochloride W-19053,Duranest,W19053,W 19053 Sodium Channel
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.
T22675 Co 102862 V 102862 Others , Sodium Channel
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.
T9751 Transfluthrin Others
Transfluthrin is a volatile pyrethroid insecticide that targets insect voltage-gated sodium channels (VGSC).
T2523 Rufinamide CGP 33101,E 2080,RUF 331 Sodium Channel
Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders.
T7579 1-BCP Piperonylic acid piperidide GluR , iGluR
1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.
T6571 Lomerizine dihydrochloride Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796 Calcium Channel
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine.
T11307 Fluxametamide GABA Receptor
Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225...
T23497 UK 78282 hydrochloride Potassium Channel
UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.
T7899 VU0810464 Potassium Channel
VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator.
T12181 NaV1.7 inhibitor-1 Sodium Channel
NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).
T7066 Fosphenytoin disodium Fosphenytoin sodium,ACC-9653 Sodium Channel
Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker
T12786 RY785 Potassium Channel
RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.
T2196 Fipronil Fluocyanobenpyrazole,Termidor P450 , GluCls , GABA Receptor
Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gat...
T6782L Benzocaine xHCl(94-09-7(free base)) Sodium Channel
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
T4298 JNJ-47965567 JNJ-479655 P2X Receptor
JNJ-47965567 (JNJ-479655) is a selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel(with pKis of 7.9 and 8.7 for human and rat P2X7, respectively).
T77642 1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride Calcium Channel
1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride can be us...
T8639 Phenibut (hydrochloride) 3-Amino-4-phenylbutyric acid hydrochloride GABA Receptor
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptor...
T68073 Flosatidil Calcium Channel
Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases, and can be used in the study of angina pectoris.
T50030 1-(2,4-difluorophenyl)guanidine hydrochloride Others
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signali...
T0796 Prilocaine hydrochloride Prilocaine HCl,Propitocaine hydrochloride,Xylonest ATPase , Sodium Channel
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions.
T0018 Procainamide hydrochloride Procapan,Procainamide HCl,Pronestyl,Procanbid DNA Methyltransferase , Sodium Channel , AChR , Autophagy
Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to...
T0124 UK-124114 UNII-A2669OWX9N,Selamectin Others
UK-124114 (Selamectin) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, sel...
T15212 Emamectin Benzoate MK-244 Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
T22361 Mepivacaine Carbocaine Sodium Channel
Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve ce...
T0802 Procaine hydrochloride Novocaine HCl,Procaine HCl Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel...
T4059 Selamectin UK-124114 Chloride channel , P-gp , Parasite
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, sel...
T4612 NS309 EGFR , Potassium Channel , HER
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...
T13387L Zatebradine hydrochloride UL-FS-49CL,UL-FS-49 Others , HCN Channel
Zatebradine hydrochloride (UL-FS-49CL) is a highly effective and effective HCN Channel inhibitor (IC50:1.96 µM). HCN Channel is an effective hyperpolarization activated loop nucleotide gated channel. Zatebradine hydrochl...

Compounds

Proflavine
T22408
Synonym: 3,6-Diaminoacridine
Target: Antibacterial
AMTB hydrochloride
T19723
Synonym: AMTB
Target: TRP/TRPV Channel
Evenamide
T15260
Synonym: NW-3509
Target: Sodium Channel
Phenytoin
T0939
Synonym: Diphenylhydantoin,5,5-Diphenylhydantoin
Target: Virus Protease, Sodium Channel
Proflavine Hemisulfate
T0438
Synonym: 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate
Target: Others, Potassium Channel, DNA, Thrombin, Antibacterial, Autophagy
Amifampridine
T4497
Synonym: 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine
Target: Others
Ivabradine hydrochloride
T2535
Synonym: S 16257-2,Ivabradine HCl
Target: Adrenergic Receptor
Phenytoin sodium
T0008
Synonym: 5,5-Diphenylhydantoin sodium salt,Diphantoine,Dilantin sodium,Diphenylhydantoin Sodium
Target: Virus Protease, Sodium Channel
Licarbazepine
T7806
Synonym: ​10,11-hydroxy-10,11 Dihydrocarbamezer
Target: Others
Aurintricarboxylic acid
T8333
Synonym: ATA,NSC-4056,NSC4056,NSC 4056
Target: Apoptosis, P2X Receptor, Influenza Virus, Topoisomerase
ZD7288
T7516
Synonym: ICI D7288
Target: HCN Channel
Meclofenamic acid
T11990
Synonym: Meclofenamate
Target: Others, Gap Junction Protein
9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
T35854
Synonym:
Target:
9(E),11(E)-12-nitro Conjugated Linoleic Acid
T37270
Synonym:
Target:
Conjugated Estrogen sodium
T19988
Synonym: Conjugated estrogens,Conest,HSDB 3076,Kestrin,Estrogens, conjugated,TAG-39
Target:
Conjugated linoleic acid
T21009
Synonym:
Target:
GalNAc unconjugated/naked Fitusiran
T74877
Synonym:
Target:
GalNAc unconjugated/naked Inclisiran
T74876
Synonym:
Target:
Epsilon-V1-2, Cys-conjugated
T80249
Synonym:
Target: PKC
PF-06305591
T12424
Synonym: PF-6305591
Target: Others
Calcium Channel antagonist 4
T77711
Synonym:
Target: Calcium Channel
Calcium Channel antagonist 3
T77712
Synonym:
Target: Calcium Channel
Etidocaine Hydrochloride
T31716
Synonym: W-19053,Duranest,W19053,W 19053
Target: Sodium Channel
Co 102862
T22675
Synonym: V 102862
Target: Others, Sodium Channel
Transfluthrin
T9751
Synonym:
Target: Others
Rufinamide
T2523
Synonym: CGP 33101,E 2080,RUF 331
Target: Sodium Channel
1-BCP
T7579
Synonym: Piperonylic acid piperidide
Target: GluR, iGluR
Lomerizine dihydrochloride
T6571
Synonym: Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796
Target: Calcium Channel
Fluxametamide
T11307
Synonym:
Target: GABA Receptor
UK 78282 hydrochloride
T23497
Synonym:
Target: Potassium Channel
VU0810464
T7899
Synonym:
Target: Potassium Channel
NaV1.7 inhibitor-1
T12181
Synonym:
Target: Sodium Channel
Fosphenytoin disodium
T7066
Synonym: Fosphenytoin sodium,ACC-9653
Target: Sodium Channel
RY785
T12786
Synonym:
Target: Potassium Channel
Fipronil
T2196
Synonym: Fluocyanobenpyrazole,Termidor
Target: P450, GluCls, GABA Receptor
Benzocaine xHCl(94-09-7(free base))
T6782L
Synonym:
Target: Sodium Channel
JNJ-47965567
T4298
Synonym: JNJ-479655
Target: P2X Receptor
1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
T77642
Synonym:
Target: Calcium Channel
Phenibut (hydrochloride)
T8639
Synonym: 3-Amino-4-phenylbutyric acid hydrochloride
Target: GABA Receptor
Flosatidil
T68073
Synonym:
Target: Calcium Channel
1-(2,4-difluorophenyl)guanidine hydrochloride
T50030
Synonym:
Target: Others
Prilocaine hydrochloride
T0796
Synonym: Prilocaine HCl,Propitocaine hydrochloride,Xylonest
Target: ATPase, Sodium Channel
Procainamide hydrochloride
T0018
Synonym: Procapan,Procainamide HCl,Pronestyl,Procanbid
Target: DNA Methyltransferase, Sodium Channel, AChR, Autophagy
UK-124114
T0124
Synonym: UNII-A2669OWX9N,Selamectin
Target: Others
Emamectin Benzoate
T15212
Synonym: MK-244
Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite
Mepivacaine
T22361
Synonym: Carbocaine
Target: Sodium Channel
Procaine hydrochloride
T0802
Synonym: Novocaine HCl,Procaine HCl
Target: Histone Demethylase, 5-HT Receptor, DNA/RNA Synthesis, Sodium Channel, NMDAR, AChR
Selamectin
T4059
Synonym: UK-124114
Target: Chloride channel, P-gp, Parasite
NS309
T4612
Synonym:
Target: EGFR, Potassium Channel, HER
Zatebradine hydrochloride
T13387L
Synonym: UL-FS-49CL,UL-FS-49
Target: Others, HCN Channel
1 2 3 4
Cat No. Product Name Synonyms Targets
T2173 Veratridine Sodium Channel
Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.
T3013 Catharanthine tartrate Catharanthine hemitartrate Others , Calcium Channel
Catharanthine tartrate (Catharanthine hemitartrate) is an alkaloid from periwinkle that inhibits voltage-gated L-type calcium channels and has antitumor and hypotensive activities.
T3021 Bulleyaconitine A Bulleyaconi cine A Sodium Channel
Bulleyaconitine A (Bulleyaconi cine A), an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
T1131 Ivermectin MK-933 Mitophagy , GluCls , P2X Receptor , SARS-CoV , HIV Protease , Antibiotic , Parasite , Autophagy , HSV
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
TN6713 6-Benzoylheteratisine Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth Sodium Channel
6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid. It can inhibits voltage-gated Na+ channels in rat brain synaptosomes
T4S1869 12-Epinapelline Others
12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ channels are responsible for these obser...
TN2347 Methylsticin Methysticin Others
Methysticin is a kavalactone isolated from the kava roots. Methylsticin (Methysticin) exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neu...
T8716 Physalin F Apoptosis
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBM...
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
TN1254 3'-Methoxydaidzein Sodium Channel
3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for colla...
T10609 Brevetoxin-3 PbTx-3 Others
Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na+ channel activator. Brevetoxin-3 has a high affinity to site 5 of the voltage-sensitive Na+ channels, inhibits the inactivation of Na+ channels.
T10278 Alamethicin Others
Alamethicin is isolated from Trichoderma viride. It is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes.
T36068 Brevetoxin B
Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junct...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03697 SCN2B Protein, Human, Recombinant (His) Human HEK293
SCN2B plays a key role in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which...
TMPY-03183 SCN2B Protein, Human, Recombinant (hFc) Human HEK293
SCN2B plays a key role in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which...
TMPY-02976 SCN3B Protein, Human, Recombinant (His) Human HEK293
SCN3B (sodium channel, voltage-gated, type III, beta, human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium ...
TMPY-02722 SCN3B Protein, Human, Recombinant (hFc) Human HEK293
SCN3B (sodium channel, voltage-gated, type III, beta, human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium ...
TMPY-05568 BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05573 CD38 Protein, Human, Recombinant (His), PE conjugated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05558 Recombinant Protein L, PE conjugated E. coli
TMPY-05572 Siglec-3/CD33 Protein, Human, Recombinant, PE conjugated Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-05567 BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05574 CD38 Protein, Human, Recombinant (His), FITC conjugated Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05571 Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His) Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains...
TMPH-03255 PLA2G5 Protein, Rat, Recombinant (His & SUMO) Rat E. coli
Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel.
TMPH-03603 KcsA Protein, S. coelicolor, Recombinant (His) Streptomyces coelicolor in vitro E. coli expression system
Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel.
TMPH-01236 DFFB Protein, Human, Recombinant (His) Human E. coli
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergi...
TMPY-03615 CSEN Protein, Human, Recombinant (His) Human E. coli
KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to th...
TMPH-01235 APOBEC3A Protein, Human, Recombinant (His & SUMO) Human E. coli
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergi...
TMPH-03751 CYBB Protein, Human, Recombinant (His) Human E. coli
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membr...
TMPH-01449 Human herpesvirus 2 (HHV-2) (strain HG52) Tegument protein VP22 (His) HHV-2 E. coli
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regula...
TMPH-02093 RIOK3 Protein, Human, Recombinant (His) Human Baculovirus
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit co...
TMPJ-00587 NRCAM Protein, Human, Recombinant (hFc) Human Human Cells
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily....
TMPH-00717 Protease 7 Protein, E. coli, Recombinant (His) E. coli E. coli
Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm...
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPH-01258 DAG1 Protein, Human, Recombinant (His & Myc) Human Baculovirus
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many ...
TMPH-01698 MORC4 Protein, Human, Recombinant (His & Myc) Human E. coli
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled wit...
TMPJ-00015 GABARAP Protein, Human, Recombinant (His & hFc) Human E. coli
Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged...
TMPH-03275 Cytoglobin Protein, Rat, Recombinant (His & Myc) Rat E. coli
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin acts on Nav1.2/SCN2A, Nav1.3/SCN3A, Na...
TMPH-01257 Dystonin Protein, Human, Recombinant (His) Human Yeast
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system. It plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many ...
TMPJ-00016 GABARAP Protein, Human, Recombinant (GST) Human E. coli
Gamma-Aminobutyric Acid Receptor-Associated Protein (GABARAP) is a ligand-gated chloride channel protein that mediates inhibitory neurotransmission and belongs to the MAP1 LC3 family. GABARAP is highly positively charged...
TMPY-02737 DPP2 Protein, Mouse, Recombinant (His) Mouse HEK293
DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity,...
TMPY-00777 DPP2 Protein, Human, Recombinant (His) Human HEK293
DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity,...
TMPH-03276 DAO Protein, Rat, Recombinant (His & Myc) Rat E. coli
Voltage-gated sodium channels (Nav) gating-modifier. Acts both as alpha- and beta-toxin, since it affects not only activation but also inactivation of Nav channels (Probable). Binds to Nav domain DII and impairs the four...
TMPY-01854 DPP10 Protein, Human, Recombinant (His) Human HEK293
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w...
TMPH-03277 DDT Protein, Rat, Recombinant (His & Myc) Rat E. coli
Voltage-gated sodium channels (Nav) gating-modifier. Acts both as alpha- and beta-toxin, since it affects not only activation but also inactivation of Nav channels (Probable). Binds to Nav domain DII and impairs the four...
TMPY-01692 NETO1 Protein, Human, Recombinant (His) Human HEK293
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDAR...
TMPH-00939 Anoctamin-5/ANO5 Protein, Human, Recombinant (His) Human HEK293
G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrah...
TMPH-00751 YjbL Protein, E. coli, Recombinant (His & KSI) E. coli E. coli
Gating-modifier toxin that potently inhibits inactivation of the mammalian Nav1.1/SCN1A sodium channel (EC(50)=38 nM). Also moderately inhibits inactivation of Nav1.2/SCN2A (EC(50)=236 nM) and Nav1.3/SCN3A (EC(50)=220 nM...
TMPH-01697 MORC3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney. Contributes to the regulation of the ...
SCN2B Protein, Human, Recombinant (His)
TMPY-03697
Species: Human
Expression System: HEK293
SCN2B Protein, Human, Recombinant (hFc)
TMPY-03183
Species: Human
Expression System: HEK293
SCN3B Protein, Human, Recombinant (His)
TMPY-02976
Species: Human
Expression System: HEK293
SCN3B Protein, Human, Recombinant (hFc)
TMPY-02722
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
TMPY-05568
Species: Human
Expression System: HEK293
CD38 Protein, Human, Recombinant (His), PE conjugated
TMPY-05573
Species: Human
Expression System: HEK293
Recombinant Protein L, PE conjugated
TMPY-05558
Species:
Expression System: E. coli
Siglec-3/CD33 Protein, Human, Recombinant, PE conjugated
TMPY-05572
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
TMPY-05567
Species: Human
Expression System: HEK293
CD38 Protein, Human, Recombinant (His), FITC conjugated
TMPY-05574
Species: Human
Expression System: HEK293
Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated
TMPY-05571
Species: Human
Expression System: HEK293
SNAP-25 Protein, Human, Recombinant (His)
TMPY-02245
Species: Human
Expression System: E. coli
PLA2G5 Protein, Rat, Recombinant (His & SUMO)
TMPH-03255
Species: Rat
Expression System: E. coli
KcsA Protein, S. coelicolor, Recombinant (His)
TMPH-03603
Species: Streptomyces coelicolor
Expression System: in vitro E. coli expression system
DFFB Protein, Human, Recombinant (His)
TMPH-01236
Species: Human
Expression System: E. coli
CSEN Protein, Human, Recombinant (His)
TMPY-03615
Species: Human
Expression System: E. coli
APOBEC3A Protein, Human, Recombinant (His & SUMO)
TMPH-01235
Species: Human
Expression System: E. coli
CYBB Protein, Human, Recombinant (His)
TMPH-03751
Species: Human
Expression System: E. coli
Human herpesvirus 2 (HHV-2) (strain HG52) Tegument protein VP22 (His)
TMPH-01449
Species: HHV-2
Expression System: E. coli
RIOK3 Protein, Human, Recombinant (His)
TMPH-02093
Species: Human
Expression System: Baculovirus
NRCAM Protein, Human, Recombinant (hFc)
TMPJ-00587
Species: Human
Expression System: Human Cells
Protease 7 Protein, E. coli, Recombinant (His)
TMPH-00717
Species: E. coli
Expression System: E. coli
GRIK2 Protein, Human, Recombinant (hFc)
TMPY-04318
Species: Human
Expression System: HEK293
DAG1 Protein, Human, Recombinant (His & Myc)
TMPH-01258
Species: Human
Expression System: Baculovirus
MORC4 Protein, Human, Recombinant (His & Myc)
TMPH-01698
Species: Human
Expression System: E. coli
GABARAP Protein, Human, Recombinant (His & hFc)
TMPJ-00015
Species: Human
Expression System: E. coli
Cytoglobin Protein, Rat, Recombinant (His & Myc)
TMPH-03275
Species: Rat
Expression System: E. coli
Dystonin Protein, Human, Recombinant (His)
TMPH-01257
Species: Human
Expression System: Yeast
GABARAP Protein, Human, Recombinant (GST)
TMPJ-00016
Species: Human
Expression System: E. coli
DPP2 Protein, Mouse, Recombinant (His)
TMPY-02737
Species: Mouse
Expression System: HEK293
DPP2 Protein, Human, Recombinant (His)
TMPY-00777
Species: Human
Expression System: HEK293
DAO Protein, Rat, Recombinant (His & Myc)
TMPH-03276
Species: Rat
Expression System: E. coli
DPP10 Protein, Human, Recombinant (His)
TMPY-01854
Species: Human
Expression System: HEK293
DDT Protein, Rat, Recombinant (His & Myc)
TMPH-03277
Species: Rat
Expression System: E. coli
NETO1 Protein, Human, Recombinant (His)
TMPY-01692
Species: Human
Expression System: HEK293
Anoctamin-5/ANO5 Protein, Human, Recombinant (His)
TMPH-00939
Species: Human
Expression System: HEK293
YjbL Protein, E. coli, Recombinant (His & KSI)
TMPH-00751
Species: E. coli
Expression System: E. coli
MORC3 Protein, Human, Recombinant (His & SUMO)
TMPH-01697
Species: Human
Expression System: E. coli
Cat No. Product Name
L7400 Sodium Channel Blocker Library

128 compounds
A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening;
L2800 Serotonin Receptor-Targeted Compound Library

275 compounds
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening;
L2610 Neurotransmitter Receptor Compound Library

1513 compounds
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;
TargetMol