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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37078 | VEGFR-2-IN-6 | VEGFR | |
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1]. | |||
T9979 | VEGFR-2-IN-29 | VEGFR | |
VEGFR-2-IN-29 is a VEGFR2 inhibitor. | |||
T10123 | VEGFR-2-IN-9 | KDR-in-4 | VEGFR |
VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer. | |||
T2056 | VEGFR-2-IN-5 | 2, 4-Pyrimidinediamine with linker,UNC0064-12,2,4-Pyrimidinediamine with linker | VEGFR |
VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis. | |||
T72924 | VEGFR-3-IN-1 | VEGFR | |
VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ... | |||
T23504 | VEGFR-IN-1 | VEGFR Tyrosine Kinase Inhibitor II | Others |
VEGFR inhibitor | |||
T79860 | TIE-2/VEGFR-2 kinase-IN-5 | VEGFR , Tie-2 | |
TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis. | |||
T68526 | VEGFR-IN-V | ||
VEGFR-IN-V is a potent, vascular endothelial growth factor receptor-2 (VEGFR-2) tyrosine kinase inhibitor. | |||
T40581 | TIE-2/VEGFR-2 kinase-IN-2 | ||
TIE-2/VEGFR-2 kinase-IN-2 is a powerful inhibitor of both VEGFR2 and Tie-2 kinases, displaying noteworthy pIC 50 values of 8.61 and 8.56, respectively. This compound acts as an anti-angiogenic agent, making it highly rel... | |||
T8817 | TIE-2/VEGFR-2 kinase-IN-1 | ||
TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1]. | |||
T63112 | VEGFR-IN-3 | ||
VEGFR-IN-3 (compound 3f), a VEGFR inhibitor, exhibits potent anticancer activity by inhibiting the growth of OVCAR-4 and MDA-MB-468 cancer cells with IC50 values of 0.29 and 0.35 μM, respectively. It has potential applic... | |||
T64060 | VEGFR-2-IN-21 | ||
VEGFR-2-IN-21 is a potent inhibitor of VEGFR-2 (IC50: 0.10 μM) and exhibits anticancer effects. | |||
T62071 | VEGFR-2-IN-16 | ||
VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects. | |||
T62901 | VEGFR-2-IN-27 | ||
VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies. | |||
T61561 | VEGFR-2-IN-18 | ||
VEGFR-2-IN-18 (Compound 15d) is a high-potency inhibitor of VEGFR-2, with an IC 50 value of 60 nM. This compound effectively initiates cell apoptosis and demonstrates significant antitumor properties [1]. | |||
T78819 | VEGFR-2-IN-33 | VEGFR | |
VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving an IC50 of 4.31 nM. This compound is utilized for hepatocel... | |||
T63822 | VEGFR-2-IN-22 | ||
VEGFR-2-IN-22 (Compound 25) is an inhibitor of VEGFR-2 and β-tubulin polymerization with an IC50=19.82 nM for VEGFR-2. VEGFR-2-IN-22 is capable of inducing apoptosis. | |||
T63804 | VEGFR-2-IN-28 | ||
VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects. | |||
T62314 | VEGFR-2-IN-25 | ||
VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 (IC50: 12.1 nM). | |||
T63002 | VEGFR-2-IN-15 | ||
VEGFR-2-IN-15 (Compound 14b) is a potent inhibitor of VEGFR-2. VEGFR-2-IN-15 inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis. |