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Search Results for " vegfr "

20

Compounds

Cat No. Product Name Synonyms Targets
T37078 VEGFR-2-IN-6 VEGFR
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].
T9979 VEGFR-2-IN-29 VEGFR
VEGFR-2-IN-29 is a VEGFR2 inhibitor.
T10123 VEGFR-2-IN-9 KDR-in-4 VEGFR
VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.
T2056 VEGFR-2-IN-5 2, 4-Pyrimidinediamine with linker,UNC0064-12,2,4-Pyrimidinediamine with linker VEGFR
VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
T72924 VEGFR-3-IN-1 VEGFR
VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ...
T23504 VEGFR-IN-1 VEGFR Tyrosine Kinase Inhibitor II Others
VEGFR inhibitor
T79860 TIE-2/VEGFR-2 kinase-IN-5 VEGFR , Tie-2
TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis.
T68526 VEGFR-IN-V
VEGFR-IN-V is a potent, vascular endothelial growth factor receptor-2 (VEGFR-2) tyrosine kinase inhibitor.
T40581 TIE-2/VEGFR-2 kinase-IN-2
TIE-2/VEGFR-2 kinase-IN-2 is a powerful inhibitor of both VEGFR2 and Tie-2 kinases, displaying noteworthy pIC 50 values of 8.61 and 8.56, respectively. This compound acts as an anti-angiogenic agent, making it highly rel...
T8817 TIE-2/VEGFR-2 kinase-IN-1
TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1].
T63112 VEGFR-IN-3
VEGFR-IN-3 (compound 3f), a VEGFR inhibitor, exhibits potent anticancer activity by inhibiting the growth of OVCAR-4 and MDA-MB-468 cancer cells with IC50 values of 0.29 and 0.35 μM, respectively. It has potential applic...
T64060 VEGFR-2-IN-21
VEGFR-2-IN-21 is a potent inhibitor of VEGFR-2 (IC50: 0.10 μM) and exhibits anticancer effects.
T62071 VEGFR-2-IN-16
VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects.
T62901 VEGFR-2-IN-27
VEGFR-2-IN-27 (compound 7a) is a potent inhibitor of VEGFR-2 (IC50: 14.8 nM) and can be used in anticancer studies.
T61561 VEGFR-2-IN-18
VEGFR-2-IN-18 (Compound 15d) is a high-potency inhibitor of VEGFR-2, with an IC 50 value of 60 nM. This compound effectively initiates cell apoptosis and demonstrates significant antitumor properties [1].
T78819 VEGFR-2-IN-33 VEGFR
VEGFR-2-IN-33 (Compound 4d), a potent VEGFR inhibitor with an IC50 value of 61.04 nM, demonstrates significant inhibition of HepG2 cell proliferation, achieving an IC50 of 4.31 nM. This compound is utilized for hepatocel...
T63822 VEGFR-2-IN-22
VEGFR-2-IN-22 (Compound 25) is an inhibitor of VEGFR-2 and β-tubulin polymerization with an IC50=19.82 nM for VEGFR-2. VEGFR-2-IN-22 is capable of inducing apoptosis.
T63804 VEGFR-2-IN-28
VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.
T62314 VEGFR-2-IN-25
VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 (IC50: 12.1 nM).
T63002 VEGFR-2-IN-15
VEGFR-2-IN-15 (Compound 14b) is a potent inhibitor of VEGFR-2. VEGFR-2-IN-15 inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.
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TargetMol