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Search Result

Search Results for " parkinson's "

Targets

GluR

209

Compounds

10

Natural Products

44

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T3464 PHCCC (-) PHCCC GluR
PHCCC ((-) PHCCC) is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGluR8.
T1880 P7C3 Others
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be...
TQ0289 LY450108 iGluR
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
T2216 Entacapone OR-611 Transferase
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
T1770 GNE-9605 LRRK2
GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).
T7729 PF-06454589 LRRK2
PF-06454589 is a potent inhibitor of LRRK2.
T22026 AGK7 Others , Sirtuin
AGK7 is an inactive control of AGK2, a selective SIRT2 inhibitor that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC50 = >5 μM, >50 μM and >50 μM for SIRT3, SIRT1, and SIRT2, respectively).
T1308 Orphenadrine hydrochloride Mebedrol,Mephenamin Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T8737 GR 125743 5-HT Receptor
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
T3278 Piribedil EU-4200,Trivastan,ET-495,Trivastal Dopamine Receptor , Histone Methyltransferase , Adrenergic Receptor
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T6726 VU0361737 ML-128,VU 0361737 GluR
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity...
T3053 CZC-25146 CHEMBL2397014 LRRK2
CZC-25146 (CHEMBL2397014) is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM for wild-type LRRK2(Leucine-rich repeat kinase-2) and G2019S LRRK2, respectively.
T1476 Pramipexole SND 919 Dopamine Receptor
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...
T5139 CZC-25146 hydrochloride LRRK2
CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.
T2148 Carbidopa monohydrate Carbidopa Hydrate,S(-)-Carbidopa Decarboxylase , Aryl Hydrocarbon Receptor
Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.
T4979 Procyclidine hydrochloride (±)-Procyclidine hydrochlorid NMDAR , iGluR
Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.
T0957 Isradipine PN 200-110 Calcium Channel , Autophagy
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc...
T6618 Orphenadrine Citrate Flexon,Flexoject,Banflex AChR , iGluR
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
T4473 Ibiglustat Venglustat,SAR402671,GZ402671 Transferase
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe...
T3217 PF-CBP1 hydrochloride PF-CBP1 HCl Epigenetic Reader Domain , Histone Acetyltransferase
PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.
T2226 Pergolide mesylate Pergolide mesylate salt,LY127809,Pergolide methanesulfonate Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.
T1336 Benztropine mesylate Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate Dopamine Receptor , AChR , Histamine Receptor
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine.
T9235 GW604714X 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]- Mitochondrial Metabolism
GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate
T2592 Ropinirole hydrochloride SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl Dopamine Receptor
Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with anti...
T0229 Rivastigmine SDZ-ENA 713,S-Rivastigmine,Exelon AChE
Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
T1628 Rivastigmine tartrate SDZ-ENA 713,ENA 713 AChR , AChE
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...
T6951 Pramipexole dihydrochloride hydrate Pramipexole 2HCl Monohydrate,Mirapex Dopamine Receptor
Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su...
T21667 FAUC-365 FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide,FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide Dopamine Receptor
FAUC-365 is a D3 dopamine receptor agonist.
T1406 Amantadine hydrochloride 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride Dopamine Receptor , Influenza Virus
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T0218 Biperiden Bipariden,Akineton,KL 373,Biperidine AChR
Biperiden (Bipariden) is a muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ...
T10512 Prenyl-IN-1 Transferase
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative st...
T24064 Fipamezole JP-1730,BVF-025,JP 1730,JP1730 Adrenergic Receptor
Fipamezole is a potent alpha2 adrenergic receptor antagonist that may be useful for studying autonomic dysfunction in Parkinson's disease.
T71707L Romergoline 2HCl Romergoline 2HCl(107052-56-2 Free base),FCE 23884 2HCl Dopamine Receptor
Romergoline 2HCl is a D1 agonist and D2 antagonist used in the study of Parkinson's disease.
T68026 (Rac)-GSK 372475 Others
(Rac)-GSK 372475 may be investigated for the treatment of Parkinson's syndrome, depression and obesity.
T13248 UK-240455 NMDAR , iGluR
UK-240455 is a potent and selective N-methyl-D-aspartic acid (NMDA) glycine receptor antagonist with neuroprotective effects and improved motor function in Parkinson's disease models, and is a potential candidate compoun...
T62304 Minzasolmin (R)-NPT200-11,UCB0599,DLX-313 Others
Minzasolmin(DLX-313) is an alpha-synuclein misfolding inhibitor for the study of Parkinson's disease.
T13267 USP30 inhibitor 11 USP30-IN-11 DUB
USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 µΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
T22595 B2 Linazolamide intermediate B impurity 2,CPNQ,5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline Others , Sirtuin
B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease
T31592 E6801 E 6801,E-6801 5-HT Receptor
E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson's disease, depression, obesity epilepsy, anxiety, and many other diseases...
T28367L1 BDBM50597431 NMDAR
BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.
T35803 C14 Ceramide (d18:1/14:0) Cer(d18:1/14:0),N-Myristoyl-D-sphingosine
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research.
T22638 CBiPES hydrochloride CBiPES HCl GluR
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used ...
T34616 Seridopidine ACR-343,ACR 343,ACR343 Dopamine Receptor
Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.
T30098 Aplindore Fumarate Aplindore,DAB-452 Fumarate,DAB-452 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H...
T6962 Rasagiline Mesylate TVP1012,AGN1135,Azilect Apoptosis , MAO , Autophagy , Monoamine Oxidase
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
T4081 MPTP hydrochloride MPTP-hydrochloride Apoptosis , Dopamine Receptor
MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, which can lead to Parkinson's disease, and is widely used in th...
T73397 ENT-C225 Trk receptor
ENT-C225 is a potent TrkB neurotrophin receptor (TrkBR) activator with neuroprotective activity for the study of Alzheimer's disease and Parkinson's disease.
T40018 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Others
4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione has potential as an anticancer, prodrug for the treatment of Parkinson's disease, and as an anti-inflammatory agent.
TQ0220 KR-33493 KR-33494,KM-819 Fas/FasL
KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.
T69188 Aloisine B AloisineB GSK-3 , CDK
Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively. Aloisine B has antiviral activity and can be used to study Alzheimer's, diabete...

Compounds

PHCCC
T3464
Synonym: (-) PHCCC
Target: GluR
P7C3
T1880
Synonym:
Target: Others
LY450108
TQ0289
Synonym:
Target: iGluR
Entacapone
T2216
Synonym: OR-611
Target: Transferase
GNE-9605
T1770
Synonym:
Target: LRRK2
PF-06454589
T7729
Synonym:
Target: LRRK2
AGK7
T22026
Synonym:
Target: Others, Sirtuin
Orphenadrine hydrochloride
T1308
Synonym: Mebedrol,Mephenamin
Target: Sodium Channel, NMDAR, Norepinephrine, iGluR, Histamine Receptor
GR 125743
T8737
Synonym:
Target: 5-HT Receptor
Piribedil
T3278
Synonym: EU-4200,Trivastan,ET-495,Trivastal
Target: Dopamine Receptor, Histone Methyltransferase, Adrenergic Receptor
VU0361737
T6726
Synonym: ML-128,VU 0361737
Target: GluR
CZC-25146
T3053
Synonym: CHEMBL2397014
Target: LRRK2
Pramipexole
T1476
Synonym: SND 919
Target: Dopamine Receptor
CZC-25146 hydrochloride
T5139
Synonym:
Target: LRRK2
Carbidopa monohydrate
T2148
Synonym: Carbidopa Hydrate,S(-)-Carbidopa
Target: Decarboxylase, Aryl Hydrocarbon Receptor
Procyclidine hydrochloride
T4979
Synonym: (±)-Procyclidine hydrochlorid
Target: NMDAR, iGluR
Isradipine
T0957
Synonym: PN 200-110
Target: Calcium Channel, Autophagy
Orphenadrine Citrate
T6618
Synonym: Flexon,Flexoject,Banflex
Target: AChR, iGluR
Ibiglustat
T4473
Synonym: Venglustat,SAR402671,GZ402671
Target: Transferase
PF-CBP1 hydrochloride
T3217
Synonym: PF-CBP1 HCl
Target: Epigenetic Reader Domain, Histone Acetyltransferase
Pergolide mesylate
T2226
Synonym: Pergolide mesylate salt,LY127809,Pergolide methanesulfonate
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Benztropine mesylate
T1336
Synonym: Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate
Target: Dopamine Receptor, AChR, Histamine Receptor
GW604714X
T9235
Synonym: 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-
Target: Mitochondrial Metabolism
Ropinirole hydrochloride
T2592
Synonym: SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl
Target: Dopamine Receptor
Rivastigmine
T0229
Synonym: SDZ-ENA 713,S-Rivastigmine,Exelon
Target: AChE
Rivastigmine tartrate
T1628
Synonym: SDZ-ENA 713,ENA 713
Target: AChR, AChE
Pramipexole dihydrochloride hydrate
T6951
Synonym: Pramipexole 2HCl Monohydrate,Mirapex
Target: Dopamine Receptor
FAUC-365
T21667
Synonym: FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide,FAUC-365 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro- phenyl)-piperazin-1-yl]-butyl}-amide
Target: Dopamine Receptor
Amantadine hydrochloride
T1406
Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride
Target: Dopamine Receptor, Influenza Virus
Biperiden
T0218
Synonym: Bipariden,Akineton,KL 373,Biperidine
Target: AChR
Prenyl-IN-1
T10512
Synonym:
Target: Transferase
Fipamezole
T24064
Synonym: JP-1730,BVF-025,JP 1730,JP1730
Target: Adrenergic Receptor
Romergoline 2HCl
T71707L
Synonym: Romergoline 2HCl(107052-56-2 Free base),FCE 23884 2HCl
Target: Dopamine Receptor
(Rac)-GSK 372475
T68026
Synonym:
Target: Others
UK-240455
T13248
Synonym:
Target: NMDAR, iGluR
Minzasolmin
T62304
Synonym: (R)-NPT200-11,UCB0599,DLX-313
Target: Others
USP30 inhibitor 11
T13267
Synonym: USP30-IN-11
Target: DUB
B2
T22595
Synonym: Linazolamide intermediate B impurity 2,CPNQ,5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline
Target: Others, Sirtuin
E6801
T31592
Synonym: E 6801,E-6801
Target: 5-HT Receptor
BDBM50597431
T28367L1
Synonym:
Target: NMDAR
C14 Ceramide (d18:1/14:0)
T35803
Synonym: Cer(d18:1/14:0),N-Myristoyl-D-sphingosine
Target:
CBiPES hydrochloride
T22638
Synonym: CBiPES HCl
Target: GluR
Seridopidine
T34616
Synonym: ACR-343,ACR 343,ACR343
Target: Dopamine Receptor
Aplindore Fumarate
T30098
Synonym: Aplindore,DAB-452 Fumarate,DAB-452
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Rasagiline Mesylate
T6962
Synonym: TVP1012,AGN1135,Azilect
Target: Apoptosis, MAO, Autophagy, Monoamine Oxidase
MPTP hydrochloride
T4081
Synonym: MPTP-hydrochloride
Target: Apoptosis, Dopamine Receptor
ENT-C225
T73397
Synonym:
Target: Trk receptor
4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
T40018
Synonym:
Target: Others
KR-33493
TQ0220
Synonym: KR-33494,KM-819
Target: Fas/FasL
Aloisine B
T69188
Synonym: AloisineB
Target: GSK-3, CDK
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T6795 Carbidopa (S)-(-)-Carbidopa,Lodosyn Decarboxylase , Aryl Hydrocarbon Receptor
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.
T6830 Epoxomicin BU-4061T,BU-4061T,Aids010837 Apoptosis , Proteasome
Epoxomicin (BU-4061T,Aids010837) is a selective proteasome inhibitor with anti-inflammatory activity, inhibits primarily the CH-L activity of the 20S proteasome, while T-L and PGPH catalytic activities are also inhibited...
T0437 Inosine INO 495,NSC 20262 ROS , Endogenous Metabolite , Adenosine Receptor
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.
T7060 Amantadine 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine Others
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
T0848 L-DOPA Levodopa,3,4-Dihydroxyphenylalanine Dopamine Receptor , Endogenous Metabolite
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...
T5S0754 Isoquercetin 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside NF-κB , Wnt/beta-catenin , NO Synthase
1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in ...
T4S2126 Ginkgetin Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...
TN5171 Tricetin Apoptosis , Others , Nrf2
Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ...
T4954L Smilagenin PYM50028,Cogane,AI3-44895,PYM 50028
Smilagenin is an orally active inducer of nonpeptide neurotrophic factor. It also prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons, and by MPTP in a mouse model of Parkinson's disease.
T15255 Etilevodopa Levodopa ethyl ester,L-DOPA ethyl ester Others
Etilevodopa is an ethyl-ester prodrug of Levodopa which is used for the treatment of Parkinson's disease (PD). It is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Levo...

Natural Products

Carbidopa
T6795
Synonym: (S)-(-)-Carbidopa,Lodosyn
Target: Decarboxylase, Aryl Hydrocarbon Receptor
Epoxomicin
T6830
Synonym: BU-4061T,BU-4061T,Aids010837
Target: Apoptosis, Proteasome
Inosine
T0437
Synonym: INO 495,NSC 20262
Target: ROS, Endogenous Metabolite, Adenosine Receptor
Amantadine
T7060
Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine
Target: Others
L-DOPA
T0848
Synonym: Levodopa,3,4-Dihydroxyphenylalanine
Target: Dopamine Receptor, Endogenous Metabolite
Isoquercetin
T5S0754
Synonym: 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,Quercetin 3-o-glucopyranoside
Target: NF-κB, Wnt/beta-catenin, NO Synthase
Ginkgetin
T4S2126
Synonym:
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Tricetin
TN5171
Synonym:
Target: Apoptosis, Others, Nrf2
Smilagenin
T4954L
Synonym: PYM50028,Cogane,AI3-44895,PYM 50028
Target:
Etilevodopa
T15255
Synonym: Levodopa ethyl ester,L-DOPA ethyl ester
Target: Others

Recombinant Proteins

Species：
Human (27)
Mouse (11)
Rat (2)
Rhesus (2)
Canine (1)
Human,Mouse,Rat (1)
Expression System：
HEK293 (20)
E. coli (15)
Baculovirus-Insect Cells (8)
Human Cells (1)
Tag：
His (26)
hFc (6)
Tag Free (4)
N-6His (2)
None (2)
C-6His (1)
C-His (1)
His,AVI (1)
hFc,AVI (1)
Cat No. Product Name Species Expression System
TMPY-02512 Alpha-Synuclein Protein, Human, Recombinant Human E. coli
Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associate...
TMPJ-00135 BDNF Protein, Human/Murine/Rat, Recombinant Human,Mouse,Rat E. coli
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. I...
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293) Human HEK293
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-01355 Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an...
TMPY-05446 CD200 Protein, Human, Recombinant (hFc) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-04356 GSK3B Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPK-01063 LRP-10 Protein, Mouse, Recombinant (His) Mouse HEK293
LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear...
TMPY-06318 Alpha-Synuclein Protein,Human,Recombinant (H50Q) Human E. coli
Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associate...
TMPY-02043 PARK7/DJ-1 Protein, Human, Recombinant (His) Human E. coli
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress....
TMPY-00568 CDNF Protein, Human, Recombinant (His) Human HEK293
Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionaril...
TMPY-06460 Alpha-Synuclein Protein, Mouse, Recombinant (His) Mouse E. coli
Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associate...
TMPY-00188 CDNF Protein, Human, Recombinant (hFc) Human HEK293
Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionaril...
TMPY-04195 CHRNB3 Protein, Human, Recombinant (hFc) Human HEK293
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protec...
TMPY-05099 GBA/glucocerebrosidase Protein, Human, Recombinant (His) Human HEK293
Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramida...
TMPY-00554 CHRNB3 Protein, Human, Recombinant (His) Human HEK293
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protec...
TMPY-01916 CDNF Protein, Mouse, Recombinant (His) Mouse HEK293
Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionaril...
TMPJ-00023 SNCA Protein, Human, Recombinant (His) Human E. coli
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and hist...
TMPJ-00683 SNCA Protein, Mouse, Recombinant Mouse E. coli
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and hist...
TMPY-02446 GAPDH Protein, Human, Recombinant (His) Human E. coli
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate...
TMPJ-01022 SUMO3 Protein, Human, Recombinant (HEK293, His) Human Human Cells
Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way...
TMPY-03227 CISD1 Protein, Human, Recombinant (His) Human E. coli
Mitochondrial dysfunction is thought to play a significant role in neurodegeneration observed in Parkinson's disease (PD), the loss of mitoNEET (CISD1), an iron-sulfur containing protein that regulates mitochondrial bioe...
TMPY-00506 GAPDH Protein, Mouse, Recombinant (His) Mouse E. coli
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate...
TMPY-02653 LRP-10 Protein, Human, Recombinant (hFc) Human HEK293
LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi...
TMPY-02472 DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Dopa Decarboxylase (DDC), also known as AADC and Aromatic-L-amino acid decarboxylase, is a 54 kDa member of the group II decarboxylase family of proteins.It is a vitamin B6-dependent homodimeric enzyme that catalyzes the...
TMPY-02748 LRP-10 Protein, Human, Recombinant (His) Human HEK293
LRP10 (low-density lipoprotein Receptor Related Protein 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a low-density lipoprotein receptor family protein. A simi...
TMPY-01060 DOPA Decarboxylase/DDC Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Dopa Decarboxylase (DDC), also known as AADC and Aromatic-L-amino acid decarboxylase, is a 54 kDa member of the group II decarboxylase family of proteins.It is a vitamin B6-dependent homodimeric enzyme that catalyzes the...
TMPY-03653 CTRL Protein, Human, Recombinant (His) Human HEK293
CTRL-1, also known as chymotrypsin-like protease, belongs to thepeptidase S1 family. CTRL-1 contains 1peptidase S1 domain. Its expression is increased in preeclampsia (PE). Placental-derived chymotrypsin-like protease is...
TMPJ-00684 SNCA Protein, Mouse, Recombinant (His) Mouse E. coli
Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's ...
TMPY-04535 GDNF Protein, Canine, Recombinant (hFc) Canine HEK293
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-02759 Kallikrein 6/KLK6 Protein, Human, Recombinant (His) Human HEK293
KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence...
TMPY-02911 GDNF Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-06970 GDNF Protein, Human, Recombinant Human E. coli
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-02401 Tyrosine Hydroxylase Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw...
TMPY-02587 Tyrosine Hydroxylase Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw...
TMPY-01071 CD200 Protein, Human, Recombinant (His) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-06791 CD200 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-03595 CD200 Protein, Rhesus, Recombinant (His) Rhesus HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-05638 CD200 Protein, Human, Recombinant (hFc & Avi) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-02331 UCHL1 Protein, Rat, Recombinant (His) Rat E. coli
Ubiquitin carboxyl-terminal hydrolase isozyme L1, also known as UCH-L1, Ubiquitin thioesterase L1, PGP9.5 and UCHL1, is a deubiqutinating enzyme with important functions in recycling of ubiquitin. Regulated proteolysis b...
TMPY-03380 CD200 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-02175 UCHL1 Protein, Mouse, Recombinant (His) Mouse E. coli
Ubiquitin carboxyl-terminal hydrolase isozyme L1, also known as UCH-L1, Ubiquitin thioesterase L1, PGP9.5 and UCHL1, is a deubiqutinating enzyme with important functions in recycling of ubiquitin. Regulated proteolysis b...
TMPY-01547 UCHL1 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin carboxyl-terminal hydrolase isozyme L1, also known as UCH-L1, Ubiquitin thioesterase L1, PGP9.5 and UCHL1, is a deubiqutinating enzyme with important functions in recycling of ubiquitin. Regulated proteolysis b...
TMPY-01160 CD200 Protein, Mouse, Recombinant (His) Mouse HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-04439 GSK3B Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
Alpha-Synuclein Protein, Human, Recombinant
TMPY-02512
Species: Human
Expression System: E. coli
BDNF Protein, Human/Murine/Rat, Recombinant
TMPJ-00135
Species: Human,Mouse,Rat
Expression System: E. coli
GDNF Protein, Human, Recombinant (HEK293)
TMPY-02792
Species: Human
Expression System: HEK293
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
TMPY-01355
Species: Human
Expression System: Baculovirus-Insect Cells
CD200 Protein, Human, Recombinant (hFc)
TMPY-05446
Species: Human
Expression System: HEK293
GSK3B Protein, Human, Recombinant (His)
TMPY-04356
Species: Human
Expression System: Baculovirus-Insect Cells
LRP-10 Protein, Mouse, Recombinant (His)
TMPK-01063
Species: Mouse
Expression System: HEK293
Alpha-Synuclein Protein,Human,Recombinant (H50Q)
TMPY-06318
Species: Human
Expression System: E. coli
PARK7/DJ-1 Protein, Human, Recombinant (His)
TMPY-02043
Species: Human
Expression System: E. coli
CDNF Protein, Human, Recombinant (His)
TMPY-00568
Species: Human
Expression System: HEK293
Alpha-Synuclein Protein, Mouse, Recombinant (His)
TMPY-06460
Species: Mouse
Expression System: E. coli
CDNF Protein, Human, Recombinant (hFc)
TMPY-00188
Species: Human
Expression System: HEK293
CHRNB3 Protein, Human, Recombinant (hFc)
TMPY-04195
Species: Human
Expression System: HEK293
GBA/glucocerebrosidase Protein, Human, Recombinant (His)
TMPY-05099
Species: Human
Expression System: HEK293
CHRNB3 Protein, Human, Recombinant (His)
TMPY-00554
Species: Human
Expression System: HEK293
CDNF Protein, Mouse, Recombinant (His)
TMPY-01916
Species: Mouse
Expression System: HEK293
SNCA Protein, Human, Recombinant (His)
TMPJ-00023
Species: Human
Expression System: E. coli
SNCA Protein, Mouse, Recombinant
TMPJ-00683
Species: Mouse
Expression System: E. coli
GAPDH Protein, Human, Recombinant (His)
TMPY-02446
Species: Human
Expression System: E. coli
SUMO3 Protein, Human, Recombinant (HEK293, His)
TMPJ-01022
Species: Human
Expression System: Human Cells
CISD1 Protein, Human, Recombinant (His)
TMPY-03227
Species: Human
Expression System: E. coli
GAPDH Protein, Mouse, Recombinant (His)
TMPY-00506
Species: Mouse
Expression System: E. coli
LRP-10 Protein, Human, Recombinant (hFc)
TMPY-02653
Species: Human
Expression System: HEK293
DOPA Decarboxylase/DDC Protein, Mouse, Recombinant (His)
TMPY-02472
Species: Mouse
Expression System: Baculovirus-Insect Cells
LRP-10 Protein, Human, Recombinant (His)
TMPY-02748
Species: Human
Expression System: HEK293
DOPA Decarboxylase/DDC Protein, Human, Recombinant (His)
TMPY-01060
Species: Human
Expression System: Baculovirus-Insect Cells
CTRL Protein, Human, Recombinant (His)
TMPY-03653
Species: Human
Expression System: HEK293
SNCA Protein, Mouse, Recombinant (His)
TMPJ-00684
Species: Mouse
Expression System: E. coli
GDNF Protein, Canine, Recombinant (hFc)
TMPY-04535
Species: Canine
Expression System: HEK293
Kallikrein 6/KLK6 Protein, Human, Recombinant (His)
TMPY-02759
Species: Human
Expression System: HEK293
GDNF Protein, Rat, Recombinant (His)
TMPY-02911
Species: Rat
Expression System: Baculovirus-Insect Cells
GDNF Protein, Human, Recombinant
TMPY-06970
Species: Human
Expression System: E. coli
Tyrosine Hydroxylase Protein, Human, Recombinant (His)
TMPY-02401
Species: Human
Expression System: Baculovirus-Insect Cells
Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)
TMPY-02587
Species: Mouse
Expression System: Baculovirus-Insect Cells
CD200 Protein, Human, Recombinant (His)
TMPY-01071
Species: Human
Expression System: HEK293
CD200 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06791
Species: Human
Expression System: HEK293
CD200 Protein, Rhesus, Recombinant (His)
TMPY-03595
Species: Rhesus
Expression System: HEK293
CD200 Protein, Human, Recombinant (hFc & Avi)
TMPY-05638
Species: Human
Expression System: HEK293
UCHL1 Protein, Rat, Recombinant (His)
TMPY-02331
Species: Rat
Expression System: E. coli
CD200 Protein, Rhesus, Recombinant (hFc)
TMPY-03380
Species: Rhesus
Expression System: HEK293
UCHL1 Protein, Mouse, Recombinant (His)
TMPY-02175
Species: Mouse
Expression System: E. coli
UCHL1 Protein, Human, Recombinant (His)
TMPY-01547
Species: Human
Expression System: E. coli
CD200 Protein, Mouse, Recombinant (His)
TMPY-01160
Species: Mouse
Expression System: HEK293
GSK3B Protein, Mouse, Recombinant (His)
TMPY-04439
Species: Mouse
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L9830 Anti-Parkinson's Disease Compound Library

908 compounds
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.
L2630 Neuronal Differentiation Compound Library

680 compounds
680 compounds related to neuronal differentiation, suitable for the drug development of nervous system disease.

Libraries

Anti-Parkinson's Disease Compound Library
L9830
Compounds: 908
Neuronal Differentiation Compound Library
L2630
Compounds: 680
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