PEA

Phenibut (Aminophenylbutyric acid) is a central depressant and derivative of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA).

Hexa-D-arginine is an inhibitor of furin,blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.

Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine

Fmoc-PEA (Example 1-2) is utilized as a cleavable linker for antibody-drug conjugates (ADC).

PEA-NBOMe hydrochloride (Compound 21) is a competitive inhibitor of phenylalanyl-tRNA synthetase (PRS) with a Ki of 0.92 μM, identified in Escherichia coli. This compound shows potential for research in developing antibacterial or antiviral agents.

Mal-Val-Ala-amide-(3)PEA-PNU-159682 is a drug-linker conjugate for ADCs, composed of the ADC linker (Mal-Val-Ala-amide-(3)PEA) and the ADC cytotoxin PNU-159682, exhibiting antitumor activity.

22393-62-0_peak 2 exhibits some aspects of the antiestrogenic activity and other actions that may be connected to the estrogenic properties. A mixture of the (Z)- and (E)-isomers (Broparestrol, INN) is used in dermatology.

Ibrutinib-MPEA is ibrutinib derivative. Ibrutinib is a covalent and irreversible BTK inhibitor that has been used to treat hematological malignancies.

Hopeachinol B is a useful organic compound for research related to life sciences and the catalog number is T126169.

PEAQX tetrasodium hydrate (PEAQX tetrasodium hydrate (459836-30-7 free base)) is an orally available NMDA antagonist that is potent and selective. The IC50 value of PEAQX tetrasodium hydrate (459836-30-7 free base) against hNMDAR 1A/2A was 270 nM and 29600 nM against hNMDAR 1A/2B, respectively.

Azonafide-PEABA is a drug moiety with cytotoxic [1].

Peanut Oil is an oil extracted from the seeds of the peanut plant, known for its nutty flavor, providing a significant nutritional source for humans.

(-)-Inpea HCl is a bioactive chemical.

d-Inpea HCl is a bioactive chemical.

Hippeastrine hydrobromide is a natural alkaloid which demonstrates significant cytotoxicity against a panel of human and murine tumor cell lines.

Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining the biochemical characteristics of the complete tau protein.

PEAQX (NVP-AAM077)(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).

PEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1 GluN2A receptors vs. GluN1 GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1 GluN2A vs. GluN1 GluN2B receptors. It is also a potent anticonvulsant in animal tests.

Cy5.5-SE (Cyanine5.5 NHS ester) DIPEA, a cyanine (CY) dye, comprises two nitrogen atoms linked by an odd number of methyl units. Characterized by long wavelength, tunable absorption and emission, high extinction coefficient, and good water solubility, alongside relatively straightforward synthesis [1], CY dyes are frequently utilized for labeling proteins, antibodies, and small molecular compounds. Their application in protein antibody labeling is achieved through a simple mixing reaction, providing a method of notable reference significance [2]. Storage instructions include protection from light.

Hippeastrine is an active alkaloid that demonstrates a potent, dose-dependent inhibitory action against topoisomerase I (Top I), achieving an IC50 of 7.25 μg mL. This compound also exhibits significant antiproliferative and anticancer activities [1].

(Rac)-PEAQX acts as an antagonist to NMDA receptors. It promotes the activation of caspase-3 and induces apoptosis in cortical striatal slice cultures.

(+)-Hopeaphenol is isolated from A. indica (L.) and V. indica Linn with an IC50 value of 21.21 μM in α-glucosidase inhibition assay.

Isohopeaphenol is a natural product for research related to life sciences. The catalog number is TN6234 and the CAS number is 197446-77-8.