assembly — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN7041	(-)-Epipodophyllotoxin		Apoptosis
	(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vit...		Apoptosis
T2773	Vindoline		Microtubule Associated
	Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.		Microtubule Associated
T16674	Pseudouridine		Endogenous Metabolite
	Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.		Endogenous Metabolite
T16366	NVR 3-778		HBV
	NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.		HBV
T1008	Cephalexin	Cefalexin,Cephacillin	Antibacterial , Antibiotic
	Cephalexin (Cephacillin) is a cephalosporin antibiotic.		Antibacterial , Antibiotic
T17011	TCH-165		Proteasome
	TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.		Proteasome
T0204	Protriptyline hydrochloride	Protriptyline HCl	5-HT Receptor , AChE
	Protriptyline Hydrochloride is the hydrochloride salt form of protriptyline, a tricyclic secondary amine with an antidepressant property. Protriptyline hydrochloride (Protriptyline HCl) blocks the re-uptake of norepineph...		5-HT Receptor , AChE
T6439	Cetylpyridinium Chloride	Cetamium,Pristacin,Hexadecylpyridinium Chloride	Others , HBV , Antibacterial
	Cetylpyridinium Chloride (Hexadecylpyridinium Chloride) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.		Others , HBV , Antibacterial
T4475	JNJ-632		HBV
	JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.		HBV
T2937	4'-Demethylepipodophyllotoxin	4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin	Microtubule Associated
	4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.		Microtubule Associated
T36850	Curvulin		Microtubule Associated
	Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.		Microtubule Associated
T16788	Rosabulin	STA 5312	Others , Microtubule Associated
	v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity.		Others , Microtubule Associated
T16016	Maytansinol	Ansamitocin P-0	Apoptosis , Microtubule Associated
	Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.		Apoptosis , Microtubule Associated
TP1159L	Boc-Gly-Gly-Phe-Gly-OH acetate	Boc-Gly-Gly-Phe-Gly-OH acetate(187794-49-6 free base),GGFG acetate
	Boc-Gly-Gly-Phe-Gly-OH acetate (GGFG acetate) is a self-assembly of N- and C-protected tetrapeptide.
T6071	Parbendazole	SKF 29044	Microtubule Associated , Parasite
	Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.		Microtubule Associated , Parasite
TQ0017	AB-423		HBV
	AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).		HBV
T21351	Maytansine	NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine	Microtubule Associated , Antibiotic
	Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.		Microtubule Associated , Antibiotic
T78557	HOIPIN-1	JTP0819958	NF-κB
	HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-kB activation.		NF-κB
T28506	Rbin-2		Phosphatase
	Rbin-2 is a cell-permeable, potent, selective and reversible inhibitor of Midasin (Mdn1).Rbin-2 directly targets the AAA+ ATPase Midasin and inhibits eukaryotic ribosome production, making it a potent probe for the study...		Phosphatase
T8951	JTP 0819958 - HOIPIN-1		IκB/IKK
	JTP-0819958 is a selective linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM[1]. JTP-0819958 suppress LUBAC-mediated NF-kB activation in vitro[2].		IκB/IKK