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Isothiafludine (NZ-4) is an orally active anti-HBV compound that acts by blocking the encapsulation of pre-genomic RNA (pgRNA) and interfering with nucleosome capsid assembly, and is used in the study of HBV infections.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $293 | In Stock | In Stock | |
| 2 mg | $436 | In Stock | In Stock | |
| 5 mg | $722 | In Stock | In Stock | |
| 10 mg | $987 | In Stock | In Stock | |
| 25 mg | $1,520 | In Stock | In Stock | |
| 50 mg | $1,980 | In Stock | In Stock |
| Description | Isothiafludine (NZ-4) is an orally active anti-HBV compound that acts by blocking the encapsulation of pre-genomic RNA (pgRNA) and interfering with nucleosome capsid assembly, and is used in the study of HBV infections. |
| In vivo | In the DHBV-infected duck model, Isothiafludine (25-100 mg/kg; oral administration, for 15 days) inhibited DHBV DNA in the sera on day 15[1]. |
| Synonyms | W-28-F, W 28 F, NZ‐4, NZ4, NZ 4 |
| Molecular Weight | 375.48 |
| Formula | C18H18FN3OS2 |
| Cas No. | 960527-22-4 |
| Smiles | O=C(NCC1=CC=C(F)C=C1)C=2N=C(SC2CC(C)C)C3=NC=CS3 |
| Relative Density. | 1.287 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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