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Search Results for " angiogenesis "

226

Compounds

46

Natural Products

143

Recombinant Proteins

4

Libraries

Cat No. Product Name Synonyms Targets
T71722 Angiogenesis inhibitor BT2
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, ang...
T74217 Angiogenesis agent 1 HIF/HIF Prolyl-Hydroxylase
Angiogenesis Agent 1 (Compound C-31), a glycoside analogue derived from salidroside, acts as an activator of the HIF-1α pathway and shows potential in diabetic hind limb ischemia research [1].
T74627 Angiogenesis inhibitor 3
Angiogenesis Inhibitor 3 (Compound 8) is a potent substance that effectively inhibits the growth of HUVEC and HCT-15 cells, demonstrating IC50 values of 1.00 and 0.71 μM, respectively. It not only induces apoptosis in th...
T83116 Angiogenesis inhibitor 4
Angiogenesis Inhibitor 4 is a potent agent for inhibiting angiogenesis, with potential applications in cancer research [1].
T9929 Ramucirumab VEGFR
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T2427 EHop-016 EHop 016 Rho , Ras
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
T9963 MPT0B390 HDAC
MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.
T6207 SC144 Apoptosis , Interleukin
SC144 is an orally active small-molecule gp130 inhibitor.
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T22086 HA 155 Autotaxin Inhibitor IV PDE
HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
TQ0317 R1530 R-1530,R 1530 VEGFR , FGFR , FLT , PDGFR
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
T6540 Ibuprofen Lysine Neoprofen COX
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.
T1394 Ibuprofen Brufen,(±)-Ibuprofe,Motrin,Advil COX
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...
T6351 MGCD-265 analog MGCD-265,Glesatinib Apoptosis , VEGFR , c-Met/HGFR
MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.
T2456 Tivozanib AV-951,KRN951 VEGFR , PDGFR , Ephrin Receptor
Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
T2690 Tranilast MK 341,SB 252218 RAAS , Prostaglandin Receptor
Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
T8491 Vorolanib CM082,X-82 VEGFR , PDGFR
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T35570 Chiauranib CS2164 c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...
T13238 Tyrphostin AG1433 SU1433,AG1433 VEGFR , PDGFR
Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).
T2586 Cabozantinib XL184,BMS-907351 Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity...
T5164 Cabozantinib hydrochloride XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351 VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
T26254 Teglarinad chloride GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride NAMPT
Teglarinad chloride (GMX-1777 chloride) is a potent inhibitor of NAMPT, the precursor of GMX1778.Teglarinad chloride has antitumor activity and acts by interfering with DNA repair and inhibiting angiogenesis.
T13050 SYP-5 HIF/HIF Prolyl-Hydroxylase , HIF
SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.
T9127 MYLS22 Others
MYLS22 is a first-in-class and selective inhibitor of optic atrophy 1 (OPA1) . MYLS22 can target endothelial OPA1 to curtail tumor growth and inhibits angiogenesis by impinging on NFkB activity and on angiogenic gene exp...
T37078 VEGFR-2-IN-6 VEGFR
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].
T15574 Incyclinide COL-3,CMT-3 MMP
Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.
T62858 HGPR91 antagonist 3 GPR
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be...
T10397 ATN-161 trifluoroacetate salt ATN-161 TFA salt Integrin
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
T63918 α-Tocopherol phosphate disodium TocP disodium,Vitamin E phosphate disodium Apoptosis , Antioxidant , Reactive Oxygen Species
α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. alpha-Tocopherol phosphate disodium ...
T17105 TM6089 HIF/HIF Prolyl-Hydroxylase
TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.
T28077 MMPP VEGFR , STAT
MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury.
T1895 SKLB 610 VEGFR , FGFR , PDGFR
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, at the concentration of 10 μM in biochemical kinase assays.
T4412 Roquinimex Linomide,LS2616,FCF89,ABR212616 TNF
Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
T4435 E7820 ER68203-00 Integrin
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
T24997 ABT-510 acetate ABT 510 acetate Apoptosis
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...
T6011 Batimastat BB94 MMP
Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.
T6271 Tipifarnib R115777,Zarnestra,IND 58359 Transferase
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnes...
T4235 Roblitinib FGF-401 FGFR
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...
T79860 TIE-2/VEGFR-2 kinase-IN-5 VEGFR , Tie-2
TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis.
T3980 Su1498 Tyrphostin SU 1498,AG 1498 VEGFR
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1,...
T2288 Motesanib AMG 706 VEGFR , c-Kit
Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-deriv...
T2624 OSI-930 OSI 930 Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
TP2308 TB500 acetate(885340-08-9 free base) Frag17-23 Acetate,TB500 Acetate Others
TB500 acetate(885340-08-9 free base) (Frag17-23 Acetate) is a synthetic version of an active region of thymosin β4. It promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, col...
T2576 Brivanib (alaninate) BMS-582664,Brivanib Alaninate VEGFR , FGFR , Autophagy
Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...
T3211 Midostaurin N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 Others , PKC
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...
T1777 Nintedanib BIBF 1120,Intedanib VEGFR , FGFR , FLT , PDGFR , Src
Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRα, and PDGFRβ (IC50=59/65 nM). Nintedanib has an...
T67746 IMS2186 Others
IMS2186 is a reagent with activity of antichoroidal neovascularization (CNV). IMS2186 could arrest cancer cell cycle in G2/M phase, result in exerting anti-proliferation and anti-angiogenesis effects. IMS2186 reduces the...
T21872 CCT018159 Apoptosis , HSP
CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90β and yeast Hsp90 with IC50s of 3.2 and 6.6 μM, respectively.CCT018159 inhibits key endothelial and tumor ce...

Compounds

Angiogenesis inhibitor BT2
T71722
Synonym:
Target:
Angiogenesis agent 1
T74217
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
Angiogenesis inhibitor 3
T74627
Synonym:
Target:
Angiogenesis inhibitor 4
T83116
Synonym:
Target:
Ramucirumab
T9929
Synonym:
Target: VEGFR
EHop-016
T2427
Synonym: EHop 016
Target: Rho, Ras
MPT0B390
T9963
Synonym:
Target: HDAC
SC144
T6207
Synonym:
Target: Apoptosis, Interleukin
JK-P3
T4425
Synonym:
Target: VEGFR
HA 155
T22086
Synonym: Autotaxin Inhibitor IV
Target: PDE
R1530
TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
Ibuprofen Lysine
T6540
Synonym: Neoprofen
Target: COX
Ibuprofen
T1394
Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil
Target: COX
MGCD-265 analog
T6351
Synonym: MGCD-265,Glesatinib
Target: Apoptosis, VEGFR, c-Met/HGFR
Tivozanib
T2456
Synonym: AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
Tranilast
T2690
Synonym: MK 341,SB 252218
Target: RAAS, Prostaglandin Receptor
Vorolanib
T8491
Synonym: CM082,X-82
Target: VEGFR, PDGFR
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
Chiauranib
T35570
Synonym: CS2164
Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase
Tyrphostin AG1433
T13238
Synonym: SU1433,AG1433
Target: VEGFR, PDGFR
Cabozantinib
T2586
Synonym: XL184,BMS-907351
Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit
Cabozantinib hydrochloride
T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
Teglarinad chloride
T26254
Synonym: GMX 1777 chloride,EB1627,GMX1777,GMX1777 chloride,GMX 1777,GMX-1777 chloride,EB-1627,EB-1627 chloride,EB1627 chloride
Target: NAMPT
SYP-5
T13050
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, HIF
MYLS22
T9127
Synonym:
Target: Others
VEGFR-2-IN-6
T37078
Synonym:
Target: VEGFR
Incyclinide
T15574
Synonym: COL-3,CMT-3
Target: MMP
hGPR91 antagonist 3
T62858
Synonym:
Target: GPR
ATN-161 trifluoroacetate salt
T10397
Synonym: ATN-161 TFA salt
Target: Integrin
α-Tocopherol phosphate disodium
T63918
Synonym: TocP disodium,Vitamin E phosphate disodium
Target: Apoptosis, Antioxidant, Reactive Oxygen Species
TM6089
T17105
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
MMPP
T28077
Synonym:
Target: VEGFR, STAT
SKLB 610
T1895
Synonym:
Target: VEGFR, FGFR, PDGFR
Roquinimex
T4412
Synonym: Linomide,LS2616,FCF89,ABR212616
Target: TNF
E7820
T4435
Synonym: ER68203-00
Target: Integrin
ABT-510 acetate
T24997
Synonym: ABT 510 acetate
Target: Apoptosis
Batimastat
T6011
Synonym: BB94
Target: MMP
Tipifarnib
T6271
Synonym: R115777,Zarnestra,IND 58359
Target: Transferase
Roblitinib
T4235
Synonym: FGF-401
Target: FGFR
TIE-2/VEGFR-2 kinase-IN-5
T79860
Synonym:
Target: VEGFR, Tie-2
Su1498
T3980
Synonym: Tyrphostin SU 1498,AG 1498
Target: VEGFR
Motesanib
T2288
Synonym: AMG 706
Target: VEGFR, c-Kit
OSI-930
T2624
Synonym: OSI 930
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
TB500 acetate(885340-08-9 free base)
TP2308
Synonym: Frag17-23 Acetate,TB500 Acetate
Target: Others
Brivanib (alaninate)
T2576
Synonym: BMS-582664,Brivanib Alaninate
Target: VEGFR, FGFR, Autophagy
Midostaurin
T3211
Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251
Target: Others, PKC
Nintedanib
T1777
Synonym: BIBF 1120,Intedanib
Target: VEGFR, FGFR, FLT, PDGFR, Src
IMS2186
T67746
Synonym:
Target: Others
CCT018159
T21872
Synonym:
Target: Apoptosis, HSP
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T3860 Isoliquiritin apioside MMP , p38 MAPK , NF-κB
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...
T6670 Silymarin Silybin B SARS-CoV
Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
T0724 Formononetin Biochanin B,Flavosil,Formononetol Apoptosis , FGFR
Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
T8846 Beta-Escin B-escin,AESCINE Immunology/Inflammation related
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
T0314 Hexylresorcinol 4-Hexylresorcinol Apoptosis , Tyrosinase , Antibacterial , Parasite
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T4586 (Rac)-Arnebin 1 beta, beta-dimethylacrylshikonin Others
(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.
T7203 Oglufanide L-Glutamyl-L-tryptophan,H-Glu-Trp-OH VEGFR , HCV Protease , Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
T3888 Scopolin Murrayin,Scopoloside Sirtuin
Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...
T0983 Penicillamine d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine Antibiotic
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...
T10117 3'-​O-​Acetylhamaudol Others
3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.
T3890 Verbenalin Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin Others
Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
T6S1292 Levistolide A Levistilide A,Diligustilide Apoptosis , Others
1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.
T9155 Fumagillol Others , Antibacterial
Fumagillol is a direct precursor of the potent angiogenesis inhibitors TNP-470 and fumagillin.
T3250 Royal Jelly acid 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid VEGFR , Endogenous Metabolite
Royal Jelly acid (Queen Bee Acid) is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
T17280 (Z)-Guggulsterone Apoptosis , VEGFR , Akt
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
TN1891 Lupiwighteone Apoptosis , BCL , PARP , Caspase
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
TN1557 Decursinol angelate ERK , VEGFR , PKC , JNK
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an...
TN2173 Salvianolic acid D (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid Others
Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effec...
T8160 EGCG Octaacetate Others , Antibacterial
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
T2S0886 Terrestrosin D Apoptosis , Others
Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of action...
T5429 Theaflavin 3,3'-digallate 8-Gingerol,TFDG Virus Protease , Antioxidant , HIV Protease , HSV
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
TN1712 Gossypin NF-κB , S6 Kinase
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i...
T2220 2-Methoxyestradiol NSC-659853,2-MeOE2,2-ME2 Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T3402 20(S)-Ginsenoside Rg3 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3 EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
T3923 Calycosin Cyclosin,3'-Hydroxyformononetin Apoptosis , Tyrosinase
Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...
T5S1632 Barlerin 8-O-Acetylshanzhiside methyl ester,ND01 VEGFR , TNF , NF-κB , Akt , Caspase
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...
T3229 Cytochalasin D ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...
T3S0153 Xanthatin Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T5S0896 Loureirin A Akt , PI3K
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...
T6S1699 Shogaol [6]-Shogaol,6-Shogaol Lipoxygenase , Autophagy
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...
T6S1487 Ginsenoside Rg5 NF-κB , COX , IGF-1R
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...
T11363 Ganoderic acid F Others
Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si...
T21005 Lupulon
Lupulon has a role as an apoptosis inducer, antimicrobial agent, angiogenesis inhibitor, and antineoplastic agent.
T26369 (+/-)-Marmesin Marmesin,(S)-Marmesin
Marmesin is a novel angiogenesis inhibitor.
TN1755 Hyperforin 5-HT Receptor , COX
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
T23773 Barbigerone Barubigeron
Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
TN5050 Sprengerinin C NADPH-oxidase , VEGFR , p38 MAPK , ROS , Akt , PI3K , mTOR , p53
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein ...
TN1615 Epitheaflagallin 3-O-gallate MMP
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis.
T74191 Tanshinol borneol ester
Tanshinol borneol ester, an angiogenesis stimulator, enhances several critical phases of angiogenesis via the Akt and MAPK signaling pathways. This compound also exhibits anti-ischemic and anti-atherosclerosis properties...
T15039 Cytochalasin E Others
Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of act...
TN5100 Taspine ERK , EGFR , BCL , VEGFR , MAPK , Akt
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful an...
T38250 L-Sepiapterin
L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat...
TN4277 Isocupressic acid cAMP , P450 , PKA
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of c...
TN5096 Tanshindiol B Histone Methyltransferase
Tanshindiol B possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors. It als...
T35577 Phosphatidylserines (bovine)
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...

Natural Products

Isoliquiritin apioside
T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
Silymarin
T6670
Synonym: Silybin B
Target: SARS-CoV
Formononetin
T0724
Synonym: Biochanin B,Flavosil,Formononetol
Target: Apoptosis, FGFR
beta-Escin
T8846
Synonym: B-escin,AESCINE
Target: Immunology/Inflammation related
Hexylresorcinol
T0314
Synonym: 4-Hexylresorcinol
Target: Apoptosis, Tyrosinase, Antibacterial, Parasite
(Rac)-Arnebin 1
T4586
Synonym: beta, beta-dimethylacrylshikonin
Target: Others
Oglufanide
T7203
Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH
Target: VEGFR, HCV Protease, Endogenous Metabolite
Scopolin
T3888
Synonym: Murrayin,Scopoloside
Target: Sirtuin
Penicillamine
T0983
Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine
Target: Antibiotic
3'-​O-​Acetylhamaudol
T10117
Synonym:
Target: Others
Verbenalin
T3890
Synonym: Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin
Target: Others
Levistolide A
T6S1292
Synonym: Levistilide A,Diligustilide
Target: Apoptosis, Others
Fumagillol
T9155
Synonym:
Target: Others, Antibacterial
Royal Jelly acid
T3250
Synonym: 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid
Target: VEGFR, Endogenous Metabolite
(Z)-Guggulsterone
T17280
Synonym:
Target: Apoptosis, VEGFR, Akt
Lupiwighteone
TN1891
Synonym:
Target: Apoptosis, BCL, PARP, Caspase
Decursinol angelate
TN1557
Synonym:
Target: ERK, VEGFR, PKC, JNK
Salvianolic acid D
TN2173
Synonym: (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid
Target: Others
EGCG Octaacetate
T8160
Synonym:
Target: Others, Antibacterial
Terrestrosin D
T2S0886
Synonym:
Target: Apoptosis, Others
Theaflavin 3,3'-digallate
T5429
Synonym: 8-Gingerol,TFDG
Target: Virus Protease, Antioxidant, HIV Protease, HSV
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Gossypin
TN1712
Synonym:
Target: NF-κB, S6 Kinase
2-Methoxyestradiol
T2220
Synonym: NSC-659853,2-MeOE2,2-ME2
Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy
20(S)-Ginsenoside Rg3
T3402
Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Calycosin
T3923
Synonym: Cyclosin,3'-Hydroxyformononetin
Target: Apoptosis, Tyrosinase
Barlerin
T5S1632
Synonym: 8-O-Acetylshanzhiside methyl ester,ND01
Target: VEGFR, TNF, NF-κB, Akt, Caspase
Cytochalasin D
T3229
Synonym:
Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K
Xanthatin
T3S0153
Synonym:
Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial
Loureirin A
T5S0896
Synonym:
Target: Akt, PI3K
Shogaol
T6S1699
Synonym: [6]-Shogaol,6-Shogaol
Target: Lipoxygenase, Autophagy
Ginsenoside Rg5
T6S1487
Synonym:
Target: NF-κB, COX, IGF-1R
Ganoderic acid F
T11363
Synonym:
Target: Others
Lupulon
T21005
Synonym:
Target:
(+/-)-Marmesin
T26369
Synonym: Marmesin,(S)-Marmesin
Target:
Hyperforin
TN1755
Synonym:
Target: 5-HT Receptor, COX
Barbigerone
T23773
Synonym: Barubigeron
Target:
Sprengerinin C
TN5050
Synonym:
Target: NADPH-oxidase, VEGFR, p38 MAPK, ROS, Akt, PI3K, mTOR, p53
Epitheaflagallin 3-O-gallate
TN1615
Synonym:
Target: MMP
Tanshinol borneol ester
T74191
Synonym:
Target:
Cytochalasin E
T15039
Synonym:
Target: Others
Taspine
TN5100
Synonym:
Target: ERK, EGFR, BCL, VEGFR, MAPK, Akt
L-Sepiapterin
T38250
Synonym:
Target:
Isocupressic acid
TN4277
Synonym:
Target: cAMP, P450, PKA
Tanshindiol B
TN5096
Synonym:
Target: Histone Methyltransferase
Phosphatidylserines (bovine)
T35577
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00685 BAI3 Protein, Human, Recombinant (His) Human HEK293 Cells
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely...
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPH-01566 Isthmin-1/ISM1 Protein, Human, Recombinant (His) Human E. coli
Acts as an angiogenesis inhibitor.
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His) Human HEK293 Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPH-00010 MMP-14 Protein, Human, Recombinant (His & SUMO) Human E. coli
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tiss...
TMPY-03382 FGF-6 Protein, Human, Recombinant Human E. coli
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ...
TMPJ-00864 VEGF165 Protein, Human, Recombinant Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-05004 FGF-4 Protein, Human, Recombinant Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His) Human HEK293 Cells
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPY-01736 COX-2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain) Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPJ-00375 HGF Protein, Human, Recombinant (His) Human HEK293 Cells
HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propepti...
TMPY-04801 Fibromodulin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FM...
TMPK-00359 Endoglin/CD105 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis...
TMPH-00949 APOLD1 Protein, Human, Recombinant (His) Human E. coli
May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability. APOLD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system...
TMPK-00645 VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migratio...
TMPK-01178 PDGFD Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Platelet‑derived growth factor D (PDGF‑D) is a new member of the PDGF family that binds the PDGFR‑β homodimer. PDGF‑D promotes the angiogenic capacity of EPCs, including proliferation, migration, adhesion and tube format...
TMPH-02927 Tenomodulin Protein, Mouse, Recombinant (His) Mouse E. coli
May be an angiogenesis inhibitor. Tenomodulin Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.6 kDa and the accession number is Q9EP64.
TMPK-00454 VEGFR2/KDR Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migratio...
TMPH-01414 GDF2 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. GDF2 Protein, H...
TMPY-01484 THSD1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ...
TMPH-02861 Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO) Mouse E. coli
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta d...
TMPH-02304 Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mito...
TMPK-01073 CLEC14A Protein, Human, Recombinant (His) Human HEK293 Cells
CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family. CLEC14A is found to be expressed in vascular endothelial cells during embryogenesis and is also implicated in ...
TMPJ-00948 Endostatin Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑termi...
TMPK-00834 CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His) Human HEK293 Cells
Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and...
TMPY-02945 Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEG...
TMPJ-00355 Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated Human HEK293 Cells
Neuropilin-1 (Npn-1, previously neuropilin; also CD304) is a 130 - 140 kDa type I transmembrane (TM) glycoprotein that regulates axon guidance and angiogenesis. Two homologues, Neuropilin-1 and Neuropilin-2, are identifi...
TMPJ-00564 PLXDC2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Mouse Plexin domain-containing protein 2(PLXDC2) is a single-pass type I membrane protein. The protein is expressed in tumor endothelium and in vessels of some normal tissues, such as the muscle and lung. PLXDC2 can inte...
TMPK-00822 VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPK-00825 VEGF121 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-04269 LAP3 Protein, Human, Recombinant (His) Human HEK293 Cells
LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine res...
TMPH-01316 ECM1 Protein, Human, Recombinant (GST & His & Myc) Human E. coli
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. ECM1 Protein, Human, ...
TMPK-01379 SEMA4D Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ...
TMPH-02508 Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar) Mouse P. pastoris (Yeast)
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells...
TMPY-02838 FGFBP3 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo...
TMPK-00403 SEMA4D Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, ...
TMPY-04084 ANGPTL1 Protein, Canine, Recombinant (hFc) Canine HEK293 Cells
Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPY-00920 SFRP2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
The Secreted frizzled-related protein (SFRP) family consists of five secreted glycoproteins in humans (SFRP1~5) that act as extracellular signaling ligands. Each SFRP is approximately 3 amino acids in length and contains...
TMPK-00303 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is ...
TMPK-00022 Galectin-1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has be...
TMPK-00727 TNFSF12/TWEAK Protein, Human, Recombinant (hFc) Human HEK293 Cells
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor ...
TMPY-00507 UNC5B Protein, Human, Recombinant (hFc) Human HEK293 Cells
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-04003 UNC5B Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-02172 Midkine Protein, Human, Recombinant Human Baculovirus Insect Cells
Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, h...
TMPK-00702 ANTXR2 Protein, Human, Recombinant (His) Human HEK293 Cells
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultu...
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BAI3 Protein, Human, Recombinant (His)
TMPJ-00685
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant
TMPJ-00603
Species: Mouse
Expression System: E. coli
Isthmin-1/ISM1 Protein, Human, Recombinant (His)
TMPH-01566
Species: Human
Expression System: E. coli
VEGF121 Protein, Human, Recombinant (His)
TMPJ-00865
Species: Human
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
TMPJ-00412
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
TMPK-00823
Species: Human
Expression System: HEK293 Cells
FGF-2 Protein, Mouse, Recombinant
TMPJ-00037
Species: Mouse
Expression System: E. coli
MMP-14 Protein, Human, Recombinant (His & SUMO)
TMPH-00010
Species: Human
Expression System: E. coli
FGF-6 Protein, Human, Recombinant
TMPY-03382
Species: Human
Expression System: E. coli
FGF-2 Protein, Rat, Recombinant
TMPJ-00842
Species: Rat
Expression System: E. coli
VEGF165 Protein, Human, Recombinant
TMPJ-00864
Species: Human
Expression System: HEK293 Cells
FGF-4 Protein, Human, Recombinant
TMPY-05004
Species: Human
Expression System: E. coli
CEACAM3 Protein, Human, Recombinant (His)
TMPY-01850
Species: Human
Expression System: HEK293 Cells
COX-2 Protein, Human, Recombinant (His)
TMPY-01736
Species: Human
Expression System: Baculovirus Insect Cells
MMP-12 Protein, Human, Recombinant (catalytic domain)
TMPY-02869
Species: Human
Expression System: E. coli
HGF Protein, Human, Recombinant (His)
TMPJ-00375
Species: Human
Expression System: HEK293 Cells
Fibromodulin Protein, Human, Recombinant (hFc)
TMPY-04801
Species: Human
Expression System: HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
TMPK-00359
Species: Human
Expression System: HEK293 Cells
APOLD1 Protein, Human, Recombinant (His)
TMPH-00949
Species: Human
Expression System: E. coli
VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
TMPK-00645
Species: Rhesus
Expression System: HEK293 Cells
PDGFD Protein, Cynomolgus, Recombinant (His)
TMPK-01178
Species: Cynomolgus
Expression System: HEK293 Cells
Tenomodulin Protein, Mouse, Recombinant (His)
TMPH-02927
Species: Mouse
Expression System: E. coli
VEGFR2/KDR Protein, Human, Recombinant (His & Avi)
TMPK-00454
Species: Human
Expression System: HEK293 Cells
GDF2 Protein, Human, Recombinant (His)
TMPH-01414
Species: Human
Expression System: P. pastoris (Yeast)
THSD1 Protein, Mouse, Recombinant (His)
TMPY-01484
Species: Mouse
Expression System: HEK293 Cells
Wnt7b Protein, Mouse, Recombinant (His & Myc & SUMO)
TMPH-02861
Species: Mouse
Expression System: E. coli
Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)
TMPH-02304
Species: Human
Expression System: E. coli
CLEC14A Protein, Human, Recombinant (His)
TMPK-01073
Species: Human
Expression System: HEK293 Cells
Endostatin Protein, Mouse, Recombinant (His)
TMPJ-00948
Species: Mouse
Expression System: HEK293 Cells
CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His)
TMPK-00834
Species: Human
Expression System: HEK293 Cells
Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)
TMPY-02945
Species: Human
Expression System: Baculovirus Insect Cells
Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated
TMPJ-00355
Species: Human
Expression System: HEK293 Cells
PLXDC2 Protein, Mouse, Recombinant (His)
TMPJ-00564
Species: Mouse
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
TMPK-00822
Species: Human
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His & Avi)
TMPK-00825
Species: Human
Expression System: HEK293 Cells
LAP3 Protein, Human, Recombinant (His)
TMPY-04269
Species: Human
Expression System: HEK293 Cells
ECM1 Protein, Human, Recombinant (GST & His & Myc)
TMPH-01316
Species: Human
Expression System: E. coli
SEMA4D Protein, Cynomolgus, Recombinant (His)
TMPK-01379
Species: Cynomolgus
Expression System: HEK293 Cells
Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar)
TMPH-02508
Species: Mouse
Expression System: P. pastoris (Yeast)
FGFBP3 Protein, Human, Recombinant (His)
TMPY-02838
Species: Human
Expression System: Baculovirus Insect Cells
SEMA4D Protein, Human, Recombinant (His & Avi)
TMPK-00403
Species: Human
Expression System: HEK293 Cells
ANGPTL1 Protein, Canine, Recombinant (hFc)
TMPY-04084
Species: Canine
Expression System: HEK293 Cells
SFRP2 Protein, Mouse, Recombinant (His)
TMPY-00920
Species: Mouse
Expression System: HEK293 Cells
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi)
TMPK-00303
Species: Human
Expression System: HEK293 Cells
Galectin-1 Protein, Human, Recombinant (hFc)
TMPK-00022
Species: Human
Expression System: HEK293 Cells
TNFSF12/TWEAK Protein, Human, Recombinant (hFc)
TMPK-00727
Species: Human
Expression System: HEK293 Cells
UNC5B Protein, Human, Recombinant (hFc)
TMPY-00507
Species: Human
Expression System: HEK293 Cells
UNC5B Protein, Rat, Recombinant (hFc)
TMPY-04003
Species: Rat
Expression System: HEK293 Cells
Midkine Protein, Human, Recombinant
TMPY-02172
Species: Human
Expression System: Baculovirus Insect Cells
ANTXR2 Protein, Human, Recombinant (His)
TMPK-00702
Species: Human
Expression System: HEK293 Cells
Cat No. Product Name
L4800 Angiogenesis related Compound Library

1353 compounds
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L2200 Tyrosine Kinase Inhibitor Library

1016 compounds
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L6120 Flavonoid Natural Product Library

514 compounds
A unique collection of 514 flavonoids can be used for high throughput and high content screening;
L8500 HIF-1 Signaling Pathway Compound Library

1336 compounds
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
TargetMol