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Search Results for " angiogenesis "

227

Compounds

47

Natural Products

451

Recombinant Proteins

4

Libraries

Cat No. Product Name Synonyms Targets
T71722 Angiogenesis inhibitor BT2
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, ang...
T74217 Angiogenesis agent 1 HIF/HIF Prolyl-Hydroxylase
Angiogenesis Agent 1 (Compound C-31), a glycoside analogue derived from salidroside, acts as an activator of the HIF-1α pathway and shows potential in diabetic hind limb ischemia research [1].
T74627 Angiogenesis inhibitor 3
Angiogenesis inhibitor 3 (compound 8) is a potent angiogenesis inhibitor. Angiogenesis inhibitor 3 inhibits the proliferation of HUVEC and HCT-15 cells, with IC 50 values of 1.00 and 0.71 μM. Angiogenesis inhibitor 3 ind...
T83116 Angiogenesis inhibitor 4
Angiogenesis Inhibitor 4 is a potent agent for inhibiting angiogenesis, with potential applications in cancer research [1].
T9929 Ramucirumab VEGFR
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.
T2427 EHop-016 EHop 016 Rho , Ras
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
T9963 MPT0B390 HDAC
MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.
T6207 SC144 Apoptosis , Interleukin
SC144 is an orally active small-molecule gp130 inhibitor.
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T22086 HA 155 Autotaxin Inhibitor IV PDE
HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
TQ0317 R1530 R-1530,R 1530 VEGFR , FGFR , FLT , PDGFR
R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.
T6540 Ibuprofen Lysine Neoprofen COX
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.
T0314 Hexylresorcinol 4-Hexylresorcinol Apoptosis , Tyrosinase , Antibacterial , Parasite
Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.
T1394 Ibuprofen Brufen,(±)-Ibuprofe,Motrin,Advil COX
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...
T6351 MGCD-265 analog MGCD-265,Glesatinib Apoptosis , VEGFR , c-Met/HGFR
MGCD-265 analog (Glesatinib) is an orally bioavailable multitargeted tyrosine kinase inhibitor with potential antineoplastic activity with IC50 of 29 nM and 10 nM for c-Met and VEGFR2, respectively.
T2456 Tivozanib AV-951,KRN951 VEGFR , PDGFR , Ephrin Receptor
Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
T2690 Tranilast MK 341,SB 252218 RAAS , Prostaglandin Receptor
Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
T8491 Vorolanib CM082,X-82 VEGFR , PDGFR
Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T35570 Chiauranib CS2164 c-Fms , VEGFR , FLT , PDGFR , c-Kit , Aurora Kinase
Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRα and c-Kit), mitosis-...
T13238 Tyrphostin AG1433 SU1433,AG1433 VEGFR , PDGFR
Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).
T2586 Cabozantinib XL184,BMS-907351 Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
Cabozantinib (BMS-907351) (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).
T5164 Cabozantinib hydrochloride XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351 VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
T37078 VEGFR-2-IN-6 VEGFR
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].
T9127 MYLS22 Others
MYLS22 is a first-in-class and selective inhibitor of optic atrophy 1 (OPA1) . MYLS22 can target endothelial OPA1 to curtail tumor growth and inhibits angiogenesis by impinging on NFkB activity and on angiogenic gene exp...
T13050 SYP-5 HIF/HIF Prolyl-Hydroxylase , HIF
SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.
T15574 Incyclinide COL-3,CMT-3 MMP
Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.
T28077 MMPP VEGFR , STAT
MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury.
T63918 α-Tocopherol phosphate disodium TocP disodium,Vitamin E phosphate disodium Apoptosis , Antioxidant , Reactive Oxygen Species
α-Tocopherol phosphate (alpha-Tocopherol phosphate) is an antioxidant that scavenges UVA1-induced reactive oxygen species (ROS) and protects against long-wave UVA1-induced cell death. alpha-Tocopherol phosphate disodium ...
T10397 ATN-161 trifluoroacetate salt ATN-161 TFA salt Integrin
ATN-161 trifluoroacetate salt (ATN-161 TFA salt) is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
T6011 Batimastat BB94 MMP
Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.
T17105 TM6089 HIF/HIF Prolyl-Hydroxylase
TM6089 is an inhibitor of Prolyl Hydroxylase that stimulates HIF activity without iron chelation, induces angiogenesis, and protects organ against ischemia.
T1895 SKLB 610 VEGFR , FGFR , PDGFR
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, at the concentration of 10 μM in biochemical kinase assays.
T4412 Roquinimex Linomide,LS2616,FCF89,ABR212616 TNF
Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
T24997 ABT-510 acetate ABT 510 acetate Apoptosis
ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...
T4435 E7820 ER68203-00 Integrin
E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
T79860 TIE-2/VEGFR-2 kinase-IN-5 VEGFR , Tie-2
TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis.
T6271 Tipifarnib R115777,Zarnestra,IND 58359 Transferase
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnes...
T2288 Motesanib AMG 706 VEGFR , c-Kit
Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-deriv...
T4235 Roblitinib FGF-401 FGFR
Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...
TP2308 TB500 acetate(885340-08-9 free base) Frag17-23 Acetate,TB500 Acetate Others
TB500 acetate(885340-08-9 free base) (Frag17-23 Acetate) is a synthetic version of an active region of thymosin β4. It promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, col...
T67746 IMS2186 Others
IMS2186 is a reagent with activity of antichoroidal neovascularization (CNV). IMS2186 could arrest cancer cell cycle in G2/M phase, result in exerting anti-proliferation and anti-angiogenesis effects. IMS2186 reduces the...
T3980 Su1498 Tyrphostin SU 1498,AG 1498 VEGFR
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1,...
T6273 Vadimezan DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404 Influenza Virus , VDA , STING , IFNAR
Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan(NSC 640488) induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide...
T2624 OSI-930 OSI 930 Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T0097L Pazopanib GW786034 VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...
T8554 KCC-07 DNA Alkylator/Crosslinker
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenes...
T60839 SLMP53-1 p53
SLMP53-1 is a p53 activator with anti-tumor activity, inhibits wt and mutp53, activates reprogramming of glucose metabolism in xenografted human tumor tissues, and interferes with angiogenesis and migration. SLMP53-1 inh...
T2576 Brivanib (alaninate) BMS-582664,Brivanib Alaninate VEGFR , FGFR , Autophagy
Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...
T3211 Midostaurin N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 Others , PKC
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...

Compounds

Angiogenesis inhibitor BT2
T71722
Synonym:
Target:
Angiogenesis agent 1
T74217
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
Angiogenesis inhibitor 3
T74627
Synonym:
Target:
Angiogenesis inhibitor 4
T83116
Synonym:
Target:
Ramucirumab
T9929
Synonym:
Target: VEGFR
EHop-016
T2427
Synonym: EHop 016
Target: Rho, Ras
MPT0B390
T9963
Synonym:
Target: HDAC
SC144
T6207
Synonym:
Target: Apoptosis, Interleukin
JK-P3
T4425
Synonym:
Target: VEGFR
HA 155
T22086
Synonym: Autotaxin Inhibitor IV
Target: PDE
R1530
TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
Ibuprofen Lysine
T6540
Synonym: Neoprofen
Target: COX
Hexylresorcinol
T0314
Synonym: 4-Hexylresorcinol
Target: Apoptosis, Tyrosinase, Antibacterial, Parasite
Ibuprofen
T1394
Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil
Target: COX
MGCD-265 analog
T6351
Synonym: MGCD-265,Glesatinib
Target: Apoptosis, VEGFR, c-Met/HGFR
Tivozanib
T2456
Synonym: AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
Tranilast
T2690
Synonym: MK 341,SB 252218
Target: RAAS, Prostaglandin Receptor
Vorolanib
T8491
Synonym: CM082,X-82
Target: VEGFR, PDGFR
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
Chiauranib
T35570
Synonym: CS2164
Target: c-Fms, VEGFR, FLT, PDGFR, c-Kit, Aurora Kinase
Tyrphostin AG1433
T13238
Synonym: SU1433,AG1433
Target: VEGFR, PDGFR
Cabozantinib
T2586
Synonym: XL184,BMS-907351
Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit
Cabozantinib hydrochloride
T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
VEGFR-2-IN-6
T37078
Synonym:
Target: VEGFR
MYLS22
T9127
Synonym:
Target: Others
SYP-5
T13050
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, HIF
Incyclinide
T15574
Synonym: COL-3,CMT-3
Target: MMP
MMPP
T28077
Synonym:
Target: VEGFR, STAT
α-Tocopherol phosphate disodium
T63918
Synonym: TocP disodium,Vitamin E phosphate disodium
Target: Apoptosis, Antioxidant, Reactive Oxygen Species
ATN-161 trifluoroacetate salt
T10397
Synonym: ATN-161 TFA salt
Target: Integrin
Batimastat
T6011
Synonym: BB94
Target: MMP
TM6089
T17105
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
SKLB 610
T1895
Synonym:
Target: VEGFR, FGFR, PDGFR
Roquinimex
T4412
Synonym: Linomide,LS2616,FCF89,ABR212616
Target: TNF
ABT-510 acetate
T24997
Synonym: ABT 510 acetate
Target: Apoptosis
E7820
T4435
Synonym: ER68203-00
Target: Integrin
TIE-2/VEGFR-2 kinase-IN-5
T79860
Synonym:
Target: VEGFR, Tie-2
Tipifarnib
T6271
Synonym: R115777,Zarnestra,IND 58359
Target: Transferase
Motesanib
T2288
Synonym: AMG 706
Target: VEGFR, c-Kit
Roblitinib
T4235
Synonym: FGF-401
Target: FGFR
TB500 acetate(885340-08-9 free base)
TP2308
Synonym: Frag17-23 Acetate,TB500 Acetate
Target: Others
IMS2186
T67746
Synonym:
Target: Others
Su1498
T3980
Synonym: Tyrphostin SU 1498,AG 1498
Target: VEGFR
Vadimezan
T6273
Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404
Target: Influenza Virus, VDA, STING, IFNAR
OSI-930
T2624
Synonym: OSI 930
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Pazopanib
T0097L
Synonym: GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
KCC-07
T8554
Synonym:
Target: DNA Alkylator/Crosslinker
SLMP53-1
T60839
Synonym:
Target: p53
Brivanib (alaninate)
T2576
Synonym: BMS-582664,Brivanib Alaninate
Target: VEGFR, FGFR, Autophagy
Midostaurin
T3211
Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251
Target: Others, PKC
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T3860 Isoliquiritin apioside MMP , p38 MAPK , NF-κB
Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...
T6670 Silymarin Silybin B SARS-CoV
Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
T0724 Formononetin Biochanin B,Flavosil,Formononetol Apoptosis , FGFR
Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.
T4586 (Rac)-Arnebin 1 beta, beta-dimethylacrylshikonin Others
(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.
T7203 Oglufanide L-Glutamyl-L-tryptophan,H-Glu-Trp-OH VEGFR , HCV Protease , Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
T8846 Beta-Escin B-escin,AESCINE Immunology/Inflammation related
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
T3888 Scopolin Murrayin,Scopoloside Sirtuin
Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...
T0983 Penicillamine d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine Antibiotic
Penicillamine (Artamine), possessing antineoplastic properties, induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Artamine is a beta dimethyl a...
T6S1292 Levistolide A Levistilide A,Diligustilide Apoptosis , Others
1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.
T10117 3'-​O-​Acetylhamaudol Others
3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.
T3250 Royal Jelly acid 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid VEGFR , Endogenous Metabolite
Royal Jelly acid (Queen Bee Acid) is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
T9155 Fumagillol Others , Antibacterial
Fumagillol is a direct precursor of the potent angiogenesis inhibitors TNP-470 and fumagillin.
T3890 Verbenalin Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin Others
Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
T17280 (Z)-Guggulsterone Apoptosis , VEGFR , Akt
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
TN1891 Lupiwighteone Apoptosis , BCL , PARP , Caspase
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
T2S0886 Terrestrosin D Apoptosis , Others
Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of action...
TN1557 Decursinol angelate ERK , VEGFR , PKC , JNK
Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion an...
TN2173 Salvianolic acid D (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid Others
Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effec...
T5429 Theaflavin 3,3'-digallate 8-Gingerol,TFDG Virus Protease , Antioxidant , HIV Protease , HSV
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...
T8160 EGCG Octaacetate Others , Antibacterial
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
T3402 20(S)-Ginsenoside Rg3 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3 EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
TN1712 Gossypin NF-κB , S6 Kinase
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i...
T2220 2-Methoxyestradiol NSC-659853,2-MeOE2,2-ME2 Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T3923 Calycosin Cyclosin,3'-Hydroxyformononetin Apoptosis , Tyrosinase
Calycosin (Cyclosin) acts as a selective estrogen receptor modulator. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Calycosin suppresses breast cancer c...
T1027 Luteolin Luteolol,Flacitran,Digitoflavone,Luteoline Apoptosis , Nrf2 , Endogenous Metabolite , PDE , Autophagy
Luteolin (Luteolol) is a naturally occurring flavonoid. The flavonoids are polyphenolic compounds found as integral components of the human diet. In vitro work has concentrated on the direct and indirect actions of flavo...
T5S1632 Barlerin 8-O-Acetylshanzhiside methyl ester,ND01 VEGFR , TNF , NF-κB , Akt , Caspase
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...
T5S0896 Loureirin A Akt , PI3K
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...
T6S1699 Shogaol [6]-Shogaol,6-Shogaol Lipoxygenase , Autophagy
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...
T3S0153 Xanthatin Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
T11363 Ganoderic acid F Others
Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si...
T21005 Lupulon
Lupulon has a role as an apoptosis inducer, antimicrobial agent, angiogenesis inhibitor, and antineoplastic agent.
T23773 Barbigerone Barubigeron
Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
T26369 (+/-)-Marmesin Marmesin,(S)-Marmesin
Marmesin is a novel angiogenesis inhibitor.
TN1755 Hyperforin 5-HT Receptor , COX
Hyperforin acts as an angiogenesis inhibitor, it as a possible antidepressant component of hypericum extracts.
TN1143 1-O-Acetyl britannilactone NF-κB , COX
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling.
TN5050 Sprengerinin C NADPH-oxidase , VEGFR , p38 MAPK , ROS , Akt , PI3K , mTOR , p53
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein ...
T74191 Tanshinol borneol ester
Tanshinol borneol ester, an angiogenesis stimulator, promoted multiple key steps of angiogenesis through Akt and MAPK signalling pathways. Tanshinol borneol ester has anti-ischemic and anti-atherosclerosis activities [1]...
TN1615 Epitheaflagallin 3-O-gallate MMP
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis.
T15039 Cytochalasin E Others
Cytochalasin E is a potent actin depolymerization agent and an epoxide containing Aspergillus-derived fungal metabolite. Cytochalasin E also inhibits angiogenesis and tumor growth. It binds and caps the barbed end of act...
TN5100 Taspine ERK , EGFR , BCL , VEGFR , MAPK , Akt
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful an...
T38250 L-Sepiapterin
L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrat...
TN4277 Isocupressic acid cAMP , P450 , PKA
Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it decrease affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of c...
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
TN5096 Tanshindiol B Histone Methyltransferase
Tanshindiol B possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors. It als...
T3229 Cytochalasin D ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...
T35577 Phosphatidylserines (bovine)
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th...
T6S1487 Ginsenoside Rg5 NF-κB , COX , IGF-1R
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...

Natural Products

Isoliquiritin apioside
T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
Silymarin
T6670
Synonym: Silybin B
Target: SARS-CoV
Formononetin
T0724
Synonym: Biochanin B,Flavosil,Formononetol
Target: Apoptosis, FGFR
(Rac)-Arnebin 1
T4586
Synonym: beta, beta-dimethylacrylshikonin
Target: Others
Oglufanide
T7203
Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH
Target: VEGFR, HCV Protease, Endogenous Metabolite
beta-Escin
T8846
Synonym: B-escin,AESCINE
Target: Immunology/Inflammation related
Scopolin
T3888
Synonym: Murrayin,Scopoloside
Target: Sirtuin
Penicillamine
T0983
Synonym: d-penicillamin,Dimethyl Cysteine,Artamine,D-(-)-Penicillamine
Target: Antibiotic
Levistolide A
T6S1292
Synonym: Levistilide A,Diligustilide
Target: Apoptosis, Others
3'-​O-​Acetylhamaudol
T10117
Synonym:
Target: Others
Royal Jelly acid
T3250
Synonym: 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid
Target: VEGFR, Endogenous Metabolite
Fumagillol
T9155
Synonym:
Target: Others, Antibacterial
Verbenalin
T3890
Synonym: Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin
Target: Others
(Z)-Guggulsterone
T17280
Synonym:
Target: Apoptosis, VEGFR, Akt
Lupiwighteone
TN1891
Synonym:
Target: Apoptosis, BCL, PARP, Caspase
Terrestrosin D
T2S0886
Synonym:
Target: Apoptosis, Others
Decursinol angelate
TN1557
Synonym:
Target: ERK, VEGFR, PKC, JNK
Salvianolic acid D
TN2173
Synonym: (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid
Target: Others
Theaflavin 3,3'-digallate
T5429
Synonym: 8-Gingerol,TFDG
Target: Virus Protease, Antioxidant, HIV Protease, HSV
EGCG Octaacetate
T8160
Synonym:
Target: Others, Antibacterial
20(S)-Ginsenoside Rg3
T3402
Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Gossypin
TN1712
Synonym:
Target: NF-κB, S6 Kinase
2-Methoxyestradiol
T2220
Synonym: NSC-659853,2-MeOE2,2-ME2
Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy
Calycosin
T3923
Synonym: Cyclosin,3'-Hydroxyformononetin
Target: Apoptosis, Tyrosinase
Luteolin
T1027
Synonym: Luteolol,Flacitran,Digitoflavone,Luteoline
Target: Apoptosis, Nrf2, Endogenous Metabolite, PDE, Autophagy
Barlerin
T5S1632
Synonym: 8-O-Acetylshanzhiside methyl ester,ND01
Target: VEGFR, TNF, NF-κB, Akt, Caspase
Loureirin A
T5S0896
Synonym:
Target: Akt, PI3K
Shogaol
T6S1699
Synonym: [6]-Shogaol,6-Shogaol
Target: Lipoxygenase, Autophagy
Xanthatin
T3S0153
Synonym:
Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial
Ganoderic acid F
T11363
Synonym:
Target: Others
Lupulon
T21005
Synonym:
Target:
Barbigerone
T23773
Synonym: Barubigeron
Target:
(+/-)-Marmesin
T26369
Synonym: Marmesin,(S)-Marmesin
Target:
Hyperforin
TN1755
Synonym:
Target: 5-HT Receptor, COX
1-O-Acetyl britannilactone
TN1143
Synonym:
Target: NF-κB, COX
Sprengerinin C
TN5050
Synonym:
Target: NADPH-oxidase, VEGFR, p38 MAPK, ROS, Akt, PI3K, mTOR, p53
Tanshinol borneol ester
T74191
Synonym:
Target:
Epitheaflagallin 3-O-gallate
TN1615
Synonym:
Target: MMP
Cytochalasin E
T15039
Synonym:
Target: Others
Taspine
TN5100
Synonym:
Target: ERK, EGFR, BCL, VEGFR, MAPK, Akt
L-Sepiapterin
T38250
Synonym:
Target:
Isocupressic acid
TN4277
Synonym:
Target: cAMP, P450, PKA
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Tanshindiol B
TN5096
Synonym:
Target: Histone Methyltransferase
Cytochalasin D
T3229
Synonym:
Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K
Phosphatidylserines (bovine)
T35577
Synonym:
Target:
Ginsenoside Rg5
T6S1487
Synonym:
Target: NF-κB, COX, IGF-1R

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00685 BAI3 Protein, Human, Recombinant (His) Human Human Cells
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely...
TMPJ-00603 TL1A Protein, Mouse, Recombinant Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-04645 TL1A Protein, Human, Recombinant (hFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-04168 ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02474 ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-02432 VEGF164 Protein, Rat, Recombinant Rat Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01717 VEGF164 Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01321 DLL4 Protein, Human, Recombinant (His) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi) Human HEK293
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) Human Human Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPY-01337 DLL4 Protein, Mouse, Recombinant (His) Mouse HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00776 DLL4 Protein, Human, Recombinant (hFc) Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated Human,Cynomolgus HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-03698 VEGF121b Protein, Human, Recombinant Human HEK293
Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-04803 DLL4 Protein, Human, Recombinant Human HEK293
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-03802 IL-17F Protein, Human, Recombinant (aa 31-163) Human E. coli
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a...
TMPY-00356 Neuropilin-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-05740 Neuropilin-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-05094 Tissue Factor Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost...
TMPY-02530 Tissue Factor Protein, Human, Recombinant (His) Human HEK293
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost...
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His) Human Human Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPJ-00037 FGF-2 Protein, Mouse, Recombinant Mouse E. coli
FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPY-02367 Neuropilin-1 Protein, Human, Recombinant (isoform b, His) Human HEK293
Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-02450 Cathepsin D Protein, Human, Recombinant (His) Human HEK293
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly...
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-03382 FGF-6 Protein, Human, Recombinant Human E. coli
FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPJ-00842 FGF-2 Protein, Rat, Recombinant Rat E. coli
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. ...
TMPY-00210 FGF-2 Protein, Mouse, Recombinant (His) Mouse E. coli
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in...
TMPH-00010 MMP-14 Protein, Human, Recombinant (His & SUMO) Human E. coli
MMP14 was first described by Sato et al. as a transmembrane protein which activates pro-MMP2 to induce tumor cell invasion. Most MMPs are secreted as inactive pro-proteinases that are activated by proteolytic cleavage. A...
TMPY-00756 FGF-1 Protein, Human, Recombinant Human E. coli
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re...
TMPY-00749 FGF-2 Protein, Human, Recombinant Human E. coli
Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01008 VEGFD Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01883 EPOR Protein, Human, Recombinant (His) Human HEK293
Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific ...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-02591 SDF-1 Protein, Human, Recombinant Human E. coli
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPJ-00864 VEGF165 Protein, Human, Recombinant Human Human Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a) Human E. coli
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-05004 FGF-4 Protein, Human, Recombinant Human E. coli
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-01850 CEACAM3 Protein, Human, Recombinant (His) Human HEK293
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPY-01007 VEGFC Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-03156 VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His) Mouse,Rat HEK293
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
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BAI3 Protein, Human, Recombinant (His)
TMPJ-00685
Species: Human
Expression System: Human Cells
TL1A Protein, Mouse, Recombinant
TMPJ-00603
Species: Mouse
Expression System: E. coli
TL1A Protein, Human, Recombinant (hFc)
TMPY-04645
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-04168
Species: Cynomolgus,Rhesus
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)
TMPY-02474
Species: Mouse
Expression System: HEK293
VEGF164 Protein, Rat, Recombinant
TMPY-02432
Species: Rat
Expression System: Baculovirus-Insect Cells
VEGF164 Protein, Mouse, Recombinant
TMPY-01717
Species: Mouse
Expression System: Baculovirus-Insect Cells
DLL4 Protein, Human, Recombinant (His)
TMPY-01321
Species: Human
Expression System: HEK293
VEGF165 Protein, Human, Recombinant (His & Avi)
TMPK-00823
Species: Human
Expression System: HEK293
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
TMPJ-00412
Species: Human
Expression System: Human Cells
DLL4 Protein, Mouse, Recombinant (His)
TMPY-01337
Species: Mouse
Expression System: HEK293
DLL4 Protein, Human, Recombinant (hFc)
TMPY-00776
Species: Human
Expression System: HEK293
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293
VEGF121b Protein, Human, Recombinant
TMPY-03698
Species: Human
Expression System: HEK293
DLL4 Protein, Human, Recombinant
TMPY-04803
Species: Human
Expression System: HEK293
IL-17F Protein, Human, Recombinant (aa 31-163)
TMPY-03802
Species: Human
Expression System: E. coli
Neuropilin-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00356
Species: Cynomolgus
Expression System: HEK293
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
TMPY-00891
Species: Human
Expression System: HEK293
Neuropilin-1 Protein, Mouse, Recombinant (His)
TMPY-05740
Species: Mouse
Expression System: HEK293
Tissue Factor Protein, Cynomolgus, Recombinant (His)
TMPY-05094
Species: Cynomolgus
Expression System: HEK293
Tissue Factor Protein, Human, Recombinant (His)
TMPY-02530
Species: Human
Expression System: HEK293
VEGF121 Protein, Human, Recombinant (His)
TMPJ-00865
Species: Human
Expression System: Human Cells
FGF-2 Protein, Mouse, Recombinant
TMPJ-00037
Species: Mouse
Expression System: E. coli
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
TMPY-02367
Species: Human
Expression System: HEK293
Cathepsin D Protein, Human, Recombinant (His)
TMPY-02450
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (His)
TMPY-00892
Species: Human
Expression System: HEK293
Neuropilin-2 Protein, Human, Recombinant (hFc)
TMPY-03763
Species: Human
Expression System: HEK293
FGF-6 Protein, Human, Recombinant
TMPY-03382
Species: Human
Expression System: E. coli
FGF-2 Protein, Rat, Recombinant
TMPJ-00842
Species: Rat
Expression System: E. coli
FGF-2 Protein, Mouse, Recombinant (His)
TMPY-00210
Species: Mouse
Expression System: E. coli
MMP-14 Protein, Human, Recombinant (His & SUMO)
TMPH-00010
Species: Human
Expression System: E. coli
FGF-1 Protein, Human, Recombinant
TMPY-00756
Species: Human
Expression System: E. coli
FGF-2 Protein, Human, Recombinant
TMPY-00749
Species: Human
Expression System: E. coli
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293
VEGFD Protein, Human, Recombinant (His)
TMPY-01008
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293
EPOR Protein, Human, Recombinant (His)
TMPY-01883
Species: Human
Expression System: HEK293
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant
TMPY-02591
Species: Human
Expression System: E. coli
VEGF165 Protein, Human, Recombinant
TMPJ-00864
Species: Human
Expression System: Human Cells
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (isoform a)
TMPY-02820
Species: Human
Expression System: E. coli
FGF-4 Protein, Human, Recombinant
TMPY-05004
Species: Human
Expression System: E. coli
CEACAM3 Protein, Human, Recombinant (His)
TMPY-01850
Species: Human
Expression System: HEK293
VEGFC Protein, Human, Recombinant (His)
TMPY-01007
Species: Human
Expression System: HEK293
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)
TMPY-03156
Species: Mouse,Rat
Expression System: HEK293
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
TMPY-01613
Species: Mouse
Expression System: HEK293
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293
Cat No. Product Name
L4800 Angiogenesis related Compound Library

1370 compounds
A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L2200 Tyrosine Kinase Inhibitor Library

1033 compounds
A unique collection of 1033 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L6120 Flavonoid Natural Product Library

477 compounds
A unique collection of 477 flavonoids can be used for high throughput and high content screening;
L8500 HIF-1 Signaling Pathway Compound Library

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
TargetMol