T31083 |
CP-868388 free base
|
702681-67-2
|
99.84%
|
|
CP-868388 free base (CP-868388) is an orally active, potent and selective PPARα agonist with hypolipidemic and anti-inflammatory activity for the study of dyslip...
|
T3090 |
Abietic Acid
|
514-10-3
|
92.6%
|
|
Abietic Acid (Sylvic acid) is the primary component of resin acid isolated from rosin.
|
TWS0787 |
Oroxin A
|
31567-75-6
|
|
|
Oroxin A (Baicalin-7-glucoside) is a partial PPARγ agonist that can activate PPARγ transcriptional activation in vitro and in vivo. Oroxin A also exhibited inhib...
|
TN3366 |
Ailanthoidol
|
156398-61-7
|
98%
|
|
Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potentia...
|
T15580 |
Inolitazone dihydrochloride
|
223132-38-5
|
98%
|
|
Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth. Ino...
|
T10505 |
PPARα-MO-1
|
810677-36-2
|
98%
|
|
PPARα-MO-1 is a potent modulator of PPARα.
|
T78806 |
PPARδ agonist 9
|
928023-21-6
|
98%
|
|
PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atherosclerotic ...
|
T79129 |
CRX000227
|
686769-92-6
|
98%
|
|
CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].
|
T79182 |
PPARγ agonist 8
|
1049800-41-0
|
98%
|
|
PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator respon...
|
T79231 |
DSO-5a
|
2195411-63-1
|
98%
|
|
DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation. I...
|
T79454 |
Anti-NASH agent 1
|
2409685-41-0
|
98%
|
|
Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH). At dosages ...
|
T79678 |
PPARγ-IN-2
|
2682078-97-1
|
98%
|
|
"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes. Furthermore, PPARγ-IN-2 counter...
|
T79949 |
Foenumoside B
|
877661-00-2
|
98%
|
|
Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotes lipo...
|
T81120 |
SP4f
|
|
98%
|
|
SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells. In Swiss albino mice, it diminishes blood glucose levels and lipid peroxidation whi...
|
T81121 |
SP4e
|
|
98%
|
|
SP4e, a PPAR-γ activator, exhibits an EC50 of 739 nM in HK-2 cells. In Swiss albino mice, it diminishes blood glucose and lipid peroxidation while enhancing glut...
|
TN1681 |
Gentianine
|
439-89-4
|
98%
|
|
Gentianine is an effective Swertiamarin derivative, which has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, diuretic and other effects, and has t...
|
T15336 |
Fonadelpar
|
515138-06-4
|
98%
|
|
Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.
|
TN4390 |
Kihadanin B
|
73793-68-7
|
98%
|
|
Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
TN3989 |
Erycibelline
|
107633-95-4
|
98%
|
|
Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
|