T14948 |
Chiglitazar
|
743438-45-1
|
98%
|
|
Chiglitazar is a dual agonist of PPARα/γ (EC50s: 1.2, 0.08, and 1.7 μM for PPARα, PPARγ, and PPARδ).
|
TN3655 |
Cimiside E
|
154822-57-8
|
98%
|
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
|
TWS0787 |
Oroxin A
|
31567-75-6
|
98%
|
|
Oroxin A is a partial PPARγ agonist that can activate PPARγ transcriptional activation in vitro and in vivo. Oroxin A also exhibited inhibitory activity against ...
|
T10044 |
13-Oxo-9E,11E-octadecadienoic acid
|
29623-29-8
|
98%
|
|
13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases p...
|
T10506 |
PPAR agonist 1
|
539813-69-9
|
98%
|
|
PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.
|
TN2641 |
15-Methoxypinusolidic acid
|
769928-72-5
|
98%
|
|
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methox...
|
TN4374 |
Kaerophyllin
|
75590-33-9
|
98%
|
|
Kaerophyllin has anti-fibrotic effects, it can protect the rat liver from TAA-caused injury and fibrogenesis by suppressing hepatic inflammation and inhibiting H...
|
TQ0272 |
Balaglitazone
|
199113-98-9
|
98%
|
|
Balaglitazone is a selective partial agonist for PPARγ (EC50: 1.351 μM for human PPARγ).
|
T11754 |
Ketorolac-d5
|
1215767-66-0
|
98%
|
|
Ketorolac D5 is a deuterium labeled Ketorolac. Ketorolac is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC50s of 20 nM ...
|
TN1703 |
Glycyrin
|
66056-18-6
|
98%
|
|
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
|
T12529 |
Pparδ agonist 2
|
870884-12-1
|
98%
|
|
Pparδ agonist 2 is an agonist of PPARδ.
|
T10327 |
Ankaflavin
|
50980-32-0
|
98%
|
|
Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induc...
|
TN2535 |
1-Hydroxy-2-oxopomolic acid
|
217466-37-0
|
98%
|
|
1β-Hydroxy-2-oxopomolic acid inhibits adipocyte differentiation through downregulation of various adipocytokines by blocking PPARγ and C/EBPα expression.
|
T14356 |
AVE-8134
|
304025-09-0
|
98%
|
|
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.
|
TN3152 |
6-Acetonyldihydrochelerythrine
|
22864-92-2
|
98%
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
|
TN4860 |
Pueroside B
|
100692-54-4
|
98%
|
|
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
|
TN5149 |
Tirotundin
|
56377-67-4
|
98%
|
|
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
|
TN1055 |
Licochalcone E
|
864232-34-8
|
98%
|
|
Licochalcone E is a potential LXRβ agonist.
|
TN4094 |
Gallocatechin gallate
|
5127-64-0
|
98%
|
|
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
|
TN2228 |
Soyasaponin Aa
|
117230-33-8
|
98%
|
|
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the down...
|