cluster

LRP1 Protein, Human, Recombinant (Cluster II, hFc) is expressed in HEK293 Cells. The accession number is Q07954.

LRP1 Protein, Human, Recombinant (Cluster II, His) is expressed in HEK293 Cells. The accession number is Q07954.

Expression system: HEK293 Cells
Length: 23-449, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23-449, Full Length of Mature Protein
Activity: Not Tested

Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.

Clusterin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q06890.

Clusterin Protein, Chinese hamster, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 50.9 kDa and the accession number is G3HNJ3-1.

Expression system: HEK293 Cells
Length: 1-449, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-321, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-191, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-220, Full Length
Activity: ELISA

Expression system: E. coli
Length: 1-312, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-462, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-462, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 227-358, Partial
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 35-167, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 232-382, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-194, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-191, Full Length
Activity: Not Tested

The cluster of differentiation (CD) system is a glycosyl phosphatidylinositol anchored membrane protein that belongs to the CD38 family.It is generally used in immunophynotyping. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth. CD157 is a bifunctional ectoenzyme that exhibits both ADP-ribosyl cyclase and cyclic ADP ribose hydrolase activities followed with CD38. It plays a role in rheumatoid arthritis (RA) due to its enhanced expression in RA-derived bone marrow stromal cell lines. Studies have shown that this protein have a role in predicted to function as a cell surface receptor and an immunoregulatory molecule.

Expression system: HEK293 Cells
Length: 28-527, Extracellular Domain
Activity: Not Tested

Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repeats. This protein binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, it functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells. Defects in LDLR will result in familial hypercholesterolemia.

Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1 CD80 and B7-2 CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.