c 16

PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability. PAF (C16) (PAF (C16)) is a platelet-activating factor, a phospholipid-derived mediator and a ligand for PAF G protein-coupled receptor (PAFR). PAF (C16) has shown anti-apoptotic and anti-inflammatory activity in vitro, inhibiting Caspase-dependent apoptosis by interacting with its receptor (PAF-R) to perform cell signaling.

Boc-C16-COOH is a alkyl-chain-based PROTAC linker. Boc-C16-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.

Boc-C16-NHS ester, an alkyl/ether-based PROTAC linker, enables the synthesis of PROTACs[1].

C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.

Methylcarbamyl PAF C-16 (Carbamyl-PAF) is a platelet-activating factor analogue with PAF agonist properties, activating inflammation in pregnancy tissues and promoting preterm birth.

GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.

Amino-PEG6-amido-C16-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Amino-PEG6-amido-C16-COOH, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1].

Amino-PEG9-amido-C16-Boc is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker used in PROTAC synthesis[1].

Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker used in PROTAC synthesis [1].

C16 Ceramide (d16:1,C16:0) is a bioactive sphingolipid that induces the formation and thermal stabilization of ordered phases and gel phases enriched in palmitoyl sphingomyelin domains within palmitoyl phosphatidylcholine (POPC) bilayers. It is found in human erythrocyte sphingomyelin.

C16 Galactosylceramide is a sphingolipid compound involved in lipid metabolism and immune modulation within cells. It is applicable in research related to diabetes and other conditions.

C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) ammonium, a member of the ganglioside family, features a saturated C16:0 acyl chain. It serves as a functional receptor for the cholera toxin B subunit, although it exhibits lower efficiency in endocytic and retrograde transport pathways. C16 Ganglioside GM1 (d18:1/16:0) ammonium is applicable in diarrhea disease research.

DMTr-2'-O-C16-rC(Ac)-3'-CE-phosphoramidite (Compound 5) is an RNAi agent and an inhibitor of Ataxin-2 (ATXN2). It can be employed to investigate neurological disorders associated with ATXN2.

C16 Ceramide (Cer) (d18:1(14Z)/16:0) is a sphingolipid-derived ceramide composed of long-chain sphingoid base (d18:1) and palmitic acid (C16:0). It serves as a crucial lipid signaling molecule for apoptosis. Specifically, C16 ceramide is involved in cell cycle arrest, cell death, and the inhibition of insulin signaling.

3-Oxo-C16:1-HSL (3oxoC16:1Δ11cis(L)HSL) is an N-acyl-homoserine lactone from Pseudomonas aeruginosa that inhibits the pathogenic strains of Aspergillus vinelandii from causing crown galls on grapes, and can be used in biosensor research.

C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide.

C16-K-cBB1 is a potent, selective antimicrobial agent effective against Methicillin-resistant Staphylococcus aureus (MRSA), demonstrated by its minimal inhibitory concentration (MIC) of 1 µg/mL. This compound exhibits excellent selectivity with minimal hemolytic activity, and can eradicate MRSA cells within 120 minutes when applied at a concentration of 12.5 μg/mL.

C16 PEG-Ceramide, a polyethylene glycolylated ceramide, serves as a lipid carrier for delivery and induces autophagy. It is utilized in cancer research [1] [2].

C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16((±)-2'-hydroxy) dihydro Ceramide (d18:0/16:0) is 190249-36-6.

C16 Ceramide-1-phosphate (d18:1/16:0) ammonium salt (C16 C1P ammonium salt) is an ester product used in synthesizing nanobiomaterials.

C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is 890041-50-6.