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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15198 | Edasalonexent | CAT-1004 | NF-κB |
Edasalonexent is an orally bioavailable inhibitor of NF-κB. | |||
T76704 | Tralokinumab | CAT-354,LP 0162 | IL Receptor |
Tralokinumab is a fully human IgG4 monoclonal antibody with a high affinity for IL-13 alone. Tralokinumab's potential anti-inflammatory activity prevents IL-13 receptor interaction and subsequent downstream signaling and... | |||
T1052 | Proglumide | cholecystokinin | |
Proglumide (Binoside) is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is... | |||
TQ0038 | Brensocatib | AZD7986,INS 1007 | Proteasome |
Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively). | |||
T77747 | Adecatumumab | MT 201 | Others |
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer. | |||
T10503 | ACAT-IN-1 cis isomer | Acyltransferase | |
ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases. | |||
TP1730L | β-catenin peptide acetate(265669-37-2 free base) | Others | |
β-catenin peptide(βCATp) acetate is a naturally occurring self-peptide presented by Kb that very efficiently mediates positive selection of the OT-I thymocytes. | |||
T23109 | 3,5-Dinitrocatechol | Transferase | |
OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex. | |||
T39598 | 4-Chlorocatechol | Others | |
4-Chlorocatechol, a significant degradation product of 4-chloro-2-aminophenol (4C2AP), serves as a substrate for both catechol 1,2-dioxygenases and chlorocatechol dioxygenase [1] [2]. | |||
T35868 | BCAT-IN-2 | ||
BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be u... | |||
T1239 | Indacaterol maleate | QAB149 | Adrenergic Receptor |
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist. | |||
T9065 | 4-Isopropylcatechol | Others | |
4-Isopropylcatechol is a potent depigmenting agent and is of use in the topical therapy of selected patients with hypermelanosis. | |||
T1742 | 4E1rcat | PERK , Autophagy | |
4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM. | |||
T60812 | Cathepsin X-IN-1 | Cysteine Protease | |
Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1]. | |||
T41094 | Wnt/β-catenin agonist 2 | GSK-3 , Wnt/beta-catenin | |
Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related to signal transduction and is closely related to cancer inva... | |||
T67884 | β-catenin modulator IIa-661 | Wnt/beta-catenin | |
β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity. | |||
T60803 | Wnt/β-catenin agonist 4 | Wnt/beta-catenin | |
Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling. | |||
T2320 | Indacaterol | Adrenergic Receptor | |
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist. | |||
T15471 | Hepronicate | Megrin | Others |
Hepronicate(Megrin) is a small molecule compound with hypolipidemic and vasodilatory activity. | |||
T77522 | BCAT-IN-4 | Others | |
BCAT-IN-4 is a potent BCAT inhibitor with an IC50 value of 2.35 μM for hBCATc. BCAT-IN-4 has anticancer activity and can be used to study pancreatic ductal adenocarcinoma. | |||
TP2058L | Catestatin acetate | Catestatin acetate(142211-96-9 free base) | Endogenous Metabolite , AChR |
Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release. Catestatin acetate regulates cardiac function and blood pressure. | |||
T9696 | β-catenin-IN-2 | Wnt/beta-catenin | |
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research. | |||
T40421 | 4,5-Dichlorocatechol | Others | |
4,5-Dichlorocatechol serves as a substrate for the broad-spectrum chlorocatechol 1,2-dioxygenase in Pseudomonas chlororaphis RW71. Its inhibition constant (Ki) values for the dioxygenase enzyme are 30 nM with the Chlorob... | |||
T4548 | Procaterol hydrochloride | Adrenergic Receptor | |
Short-acting β2-adrenergic receptor agonist used to treat asthma. | |||
T6015 | Cathepsin Inhibitor 1 | Cysteine Protease | |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | |||
T22043 | BCATc Inhibitor 2 | Others | |
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,... | |||
T9988 | Wnt/β-catenin agonist 3 | Wnt/beta-catenin | |
Wnt/β-catenin agonist 3 is a Wnt/beta-catenin agonist. | |||
T8222 | Selpercatinib | LOXO-292 | c-RET |
Selpercatinib (LOXO-292) is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively) | |||
T38585 | Tetrachlorocatechol | Others | |
Tetrachlorocatechol (TCC) is a chlorinated catechol compound that serves as a metabolite of pentachlorophenol. It is prominently generated during the chlorobleaching process in pulp production and is commonly detected in... | |||
T3532 | 5S rRNA modificator | FAI,Furoyl Acylimidazole | Others |
5S rRNA modificator (FAI), used in 5S rRNA RNA modification, is a suitable electrophile for 2'-hydroxyl acylation on structured RNA molecules. | |||
T1850 | Balicatib | AAE581 | Cysteine Protease |
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis. | |||
T22344 | Icatibant Acetate | Bradykinin Receptor | |
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. | |||
T14044 | 4E2RCat | PERK | |
4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5 μM). | |||
T37504L | Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) | Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) | |
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies... | |||
T5198 | Bobcat339 | Bobcat339 hydrochloride | DNA Methyltransferase |
Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a. | |||
TP1125 | Insulin(cattle) | Insulin from bovine pancreas | IGF-1R |
Insulin bovine (Insulin from bovine pancreas) is a biologically derived two-chain polypeptide hormone, synthesized in vivo by pancreatic β cells. It is frequently utilized as a growth supplement in cell culture applicati... | |||
T77555 | 3-Methoxycatechol | 1,2-Dihydroxy-3-methoxybenzene | Antiviral |
3-Methoxycatechol is a lignin-derived renewable chemical that promotes carcinogenesis in the esophagus.1,2-Dihydroxy-3-methoxybenzen exhibits strong antiviral activity against encephalomyelitis virus (EMCV). | |||
T6035 | Odanacatib | MK-0822 | Cysteine Protease |
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity. | |||
T2364 | Tucatinib | ARRY-380,Irbinitinib,ONT-380 | EGFR , HER |
Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM). | |||
T6078 | Saracatinib | AZD0530 | EGFR , Src , BTK , Autophagy |
Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes. | |||
T62494 | Cathepsin C-IN-5 | ||
Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active inhibitor of Cathepsin C, demonstrating IC50 values of 59.9 nM for Cat C, and showing significantly lower potency against Cat L (4.26 µM), Cat S,... | |||
T64159 | Cathepsin K inhibitor 2 | ||
Cathepsin K inhibitor 2 is a potent inhibitor of cathepsin K. Cathepsin K (Cat K) is a cysteine protease expressed under the control of the CTSK gene, which is closely related to osteoporosis and hydrolyses collagen. cat... | |||
T63854 | Cathepsin C-IN-3 | ||
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM). | |||
T62659 | Cathepsin C-IN-4 | ||
Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM). | |||
T71658 | Indacaterol xinafoate | ||
Indacaterol xinafoate is an ultra-long-acting beta-adrenoceptor agonist. | |||
T64727 | Magnesium silicate adsorbent(Synthetic) | ||
Magnesium silicate adsorbent(Synthetic) is a useful organic compound for research related to life sciences and the catalog number is T64727. | |||
T71659 | Indacaterol acetate | ||
Indacaterol acetate is an ultra-long-acting beta-adrenoceptor agonist. | |||
T82235 | HCA/Wnt/β-catenin-IN-1 | ||
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8 nM, respectively. Additionally, this compound attenuates P-g... | |||
T125331 | 9,16-Dioxo-10,12,14-octadecatrienoic acid | ||
9,16-Dioxo-10,12,14-octadecatrienoic acid is a useful organic compound for research related to life sciences and the catalog number is T125331. | |||
T126040 | Imbricataflavone A | ||
Imbricataflavone A is a useful organic compound for research related to life sciences and the catalog number is T126040. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3845 | (+)-Gallocatechin | Gallocatechol,D-Gallocatechin | Others |
(+)-Gallocatechin (Gallocatechol) possesses free radical scavenging ability. (+)-Gallocatechin has moderate affinity to the human cannabinoid receptor. | |||
T8010 | Dibutyl sebacate | Dibutyl decanedioate | Others |
Dibutyl sebacate (Dibutyl decanedioate) is an organic chemical which is mainly used as a plasticizer in the production of plastics. | |||
TN6785 | Dihydrocatalpol | (2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol | Others |
Dihydrocatalpol ((2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,4,5,5a,6,6a-hexahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol),a natural product ob... | |||
T3018 | Protocatechualdehyde | Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde | Reactive Oxygen Species , Antibacterial |
Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an anti... | |||
T2778 | (+)-Catechin Hydrate | Antioxidant , COX | |
(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. | |||
TN2540 | 1-Hydroxybaccatin I | Others | |
1-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions. | |||
T13305 | Viridicatol | Anti-infection , Antifungal | |
Viridicatol, with potent antibacterial activity against Staphylococcus aureus(MIC: 15.6 μg/mL), is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. | |||
TN1608 | (-)-Epigallocatechin-3-(3''-O-methyl) gallate | (-)-EGCG-3''-O-ME | Antioxidant , Antibacterial |
(-)-Epigallocatechin-3-(3''-O-methyl) gallate ((-)-EGCG-3''-O-ME) is a natural product isolated from tea leaves with strong antioxidant, cytotoxic and antibacterial activity, which enhances the adhesive stability of etch... | |||
T2987 | (-)-Epigallocatechin | l-Epigallocatechin,Epigallocatechin,EGC | MMP , Autophagy |
(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their transformation into amyloid fibrils. | |||
T3807 | (-)-Gallocatechin gallate | (-)-gallocatechin-3-O-gallate,(-)-Gallocatechol gallate,Gallocatechin gallate | Others |
(-)-Gallocatechin gallate ((-)-gallocatechin-3-O-gallate) is the polyphenol isolated from tea, with cancer-preventive activities. (-)-Gallocatechin gallate decreases osteoclastogenesis at 20 microM. | |||
T0822 | Catechin | Catechinic acid,D-Catechin,(+)-Catechin,Cianidanol,Catechuic acid | Apoptosis , Influenza Virus , COX , Endogenous Metabolite |
Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant. | |||
T0562 | Protocatechuic acid | 3, 4-Dihydroxybenzoic acid,Protocatechuate,3,4-Dihydroxybenzoic acid | Others |
Protocatechuic acid (3, 4-Dihydroxybenzoic acid) (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protective agent ... | |||
T3023 | Catharanthine sulfate | AChR | |
Catharanthine inhibits nicotinic receptor-mediated diaphragm contractions. | |||
T2782L | Catharanthine Tartrate(2468-21-5(free base)) | Calcium Channel | |
Catharanthine Tartrate is a natural product isolated from Madagascar periwinkle, Catharanthine Tartrate inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity | |||
TN7047 | 6-O-Methylcatalpol | Others | |
6-O-Methylcatalpol is a natural product that is isolated from the roots of S. ningpoensis. | |||
TN7036 | N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide | (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14 | Wnt/beta-catenin |
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pa... | |||
T3682 | (-)-Catechin gallate | (-)-Catechin 3-O-gallate,(-)-Catechin 3-gallate | Others , COX |
(-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of 6PGD, IDH. (-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of human Beta-secretase. (-)-Catechin gallate ((-)-Catechin 3-O-gallat... | |||
T77563 | 4-Ethylcatechol | DNA | |
4-Ethylcatechol is present in red wine and can be extracted from Glechoma longituba (NaKai) Kupr.4-Ethylcatechol induces DNA damage in the presence of Cu(II).4-Ethylcatechol is a potent antiplatelet compound. | |||
T2782 | Catharanthine | (+)-3, 4-Didehydrocoronaridine,(+)-3,4-Didehydrocoronaridine | Calcium Channel , AChR |
Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM). | |||
T2780 | Catalpol | Catalpinoside,Digitalis purpurea L | Others , HBV |
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects. | |||
T8255 | (±)-Catechin | (±)-Catechin hydrate | ROS , COX |
(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress. | |||
T2988 | (-)-Epigallocatechin Gallate | Epigallocatechol Gallate,EGCG | Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy |
(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor... | |||
T4779 | 4-Methylcatechol | p-Methylcatechol,Homocatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene | Others , Endogenous Metabolite |
4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce t... | |||
T2856 | (-)-Epicatechin | L-Epicatechin,Epicatechin,(-)-Epicatechol | Ferroptosis , COX , Endogenous Metabolite |
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. | |||
T5132 | 9-dihydro-13-acetylbaccatin III | 13-Acetyl-9-dihydrobaccatin III,9-DHAB III | Apoptosis |
9-dihydro-13-acetylbaccatin III (9-DHAB III)is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR. | |||
TN6832 | Sulcatone | 6-methylhept-5-en-2-one,6-Methyl-5-hepten-2-one | Endogenous Metabolite |
Sulcatone (6-Methyl-5-hepten-2-one) is an alarm/panic pheromone produce by ant species. | |||
T4810 | Pyrocatechuic acid | 3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid | Others , Endogenous Metabolite |
Pyrocatechuic acid (Catecholcarboxylic acid), a normal human benzoic acid metabolite found in plasma, has increased levels after aspirin ingestion. | |||
TN1274 | 4-Allylcatechol | 4-Allylpyrocatechol,Hydroxychavicol | Others |
4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ... | |||
T19229 | Catalase | Others | |
Catalase is an essential enzyme in the metabolism of H2O2 and reactive oxygen species (ROS). The expression and localization of Catalase are markedly altered in tumors. | |||
T3013 | Catharanthine tartrate | Catharanthine hemitartrate | Others , Calcium Channel |
Catharanthine tartrate (Catharanthine hemitartrate) is an alkaloid from periwinkle that inhibits voltage-gated L-type calcium channels and has antitumor and hypotensive activities. | |||
T3742 | 3-Methylcatechol | 3-Methylpyrocatechol,2,3-Toluenediol,2,3-dihydroxytoluene | Others |
3-Methylcatechol (2,3-Toluenediol) is an active biochemical. | |||
T3828 | (-)-Gallocatechin | (2S,3R)-gallocatechin,(−)-GC | Others |
(-)-Gallocatechin ((−)-GC) has free radical scavenging ability and moderate affinity to the human cannabinoid receptor. | |||
TN3609 | Catalposide | Hydroxybenzoyl catalpol | ERK , IL Receptor , TNF , NOS , NF-κB , NO Synthase , PPAR , Autophagy |
Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties. | |||
T13597 | (-)-Catechin | (-)-Catechuic acid,(-)-Cianidanol | COX |
(-)-Catechin ((-)-Cianidanol), an isomer of catechin, inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. | |||
T2197 | 10-Deacetylbaccatin III | Others | |
10-Deacetylbaccatin-III is an intermediate for taxol analog preparations with anti-cancer activity. | |||
T2732 | (-)-Epicatechin gallate | (−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG | Virus Protease , COX , Autophagy |
(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin... | |||
T2788 | Baccatin III | Baccatin Ⅲ | Others |
Baccatin III (Baccatin Ⅲ) is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It has immunomodulatory and anticancer chemotherapeutic activities. | |||
T4242 | Catechin 3-rhamnoside | Others | |
Catechin 3-rhamnoside has antioxidant activity. | |||
TN4868 | Pyrocatechol monoglucoside | Others | |
Pyrocatechol monoglucoside is a natural product for research related to life sciences. The catalog number is TN4868 and the CAS number is 2400-71-7. | |||
TN2615 | 13-O-Cinnamoylbaccatin III | Others | |
13-O-Cinnamoylbaccatin III is a natural product from Taxus yunnanensis. | |||
TN4250 | Imbricatolic acid | p53 | |
Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells. | |||
TN3607 | Catalpalactone | cAMP | |
Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone c... | |||
TN3965 | (-)-Epicatechin-3-(3''-O-methyl) gallate | Others | |
(-)-Epicatechin-3-(3''-O-methyl) gallate is a natural product from Acacia catechu (L.F.) Willd. | |||
TN5440 | Catechin-7-O-xyloside | Catechin 7-O-β-D-xylopyranoside | Others |
Catechin-7-O-xyloside(C7Ox) has anti-cancer activity, it induces apoptosis via endoplasmic reticulum stress and mitochondrial dysfunction in human non-small cell lung carcinoma H1299 cells. | |||
T21159 | Bis(2-ethylhexyl) sebacate | Di(2-ethylhexyl) Sebacate,Dioctyl Sebacate | |
Bis(2-ethylhexyl) sebacate is used as a plasticizer in preparing ion-selective electrodes. It is an important raw material and intermediate used in organic synthesis, agrochemicals, pharmaceuticals and dyestuff fields. | |||
TN6135 | Methoxyimbricatin | ||
Methoxyimbricatin is a natural product for research related to life sciences. The catalog number is TN6135 and the CAS number is 233759-30-3. | |||
TN4094 | Gallocatechin gallate | IL Receptor , NF-κB , ROS , MAPK , PPAR , Fatty Acid Synthase | |
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabeti... | |||
TN3608 | Catalpin | Others | |
Catalpin exhibited mutagenic activity towards Salmonella typhimurium strain TA100 in the presence and absence of rat liver homogenate (S9) mix in Ames' test. | |||
T82773 | Catechin 7-O-β-D-glucopyranoside | ||
Catechin 7-O-β-D-glucopyranoside, a natural product identified in Ulmus davidiana and Paeonia obovata, demonstrates oral activity and possesses antioxidant and anti-inflammatory properties. It mitigates mitochondrial dys... | |||
T38335 | Viridicatin | ||
Viridicatin is a natural product for research related to life sciences. The catalog number is T38335 and the CAS number is 129-24-8. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00764 | Catalase/CAT Protein, Human, Recombinant | Human | E. coli |
Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase ... | |||
TMPY-02751 | Cathepsin S Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS... | |||
TMPH-00080 | Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) | Arabidopsis thaliana | E. coli |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. | |||
TMPH-00345 | Catalase Protein, Capsicum annuum, Recombinant (His) | Capsicum annuum | E. coli |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. | |||
TMPY-02464 | Catalase/CAT Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Catalase is a ubiquitously expressed enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a tetramer of four polypeptides chains containing four porphyrin heme groups that allow the enz... | |||
TMPU-00002 | SOS1-Cat Protein, Human, Recombinant (His) | Human | E. coli |
Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM... | |||
TMPY-01948 | COQ7 Protein, Human, Recombinant (His) | Human | HEK293 |
Ubiquinone biosynthesis protein COQ7 homolog, also known as Coenzyme Q biosynthesis protein 7 homolog, Timing protein clk-1 homolog and COQ7, is a mitochondrion inner membrane and peripheral membrane protein which bel... | |||
TMPY-02205 | Beta-Catenin Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is p... | |||
TMPY-02869 | MMP-12 Protein, Human, Recombinant (catalytic domain) | Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-02450 | Cathepsin D Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly... | |||
TMPY-00735 | Cathepsin S Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS... | |||
TMPY-00731 | Cathepsin B Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas... | |||
TMPY-02699 | Cathepsin Z Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin Z (CTSZ), also known as Cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from ot... | |||
TMPY-04503 | Cathepsin B Protein, Rat, Recombinant (His) | Rat | HEK293 |
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas... | |||
TMPY-02985 | Beta-Catenin Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
beta-Catenin, also known as CTNNB1, is a member of the armadillo family of proteins. These proteins have multiple copies of the so-called armadillo repeat domain, which is specialized for protein-protein binding. It is p... | |||
TMPY-00736 | Cathepsin Z Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Cathepsin Z (CTSZ), also known as Cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from ot... | |||
TMPY-00730 | Cathepsin A Protein, Human, Recombinant (His) | Human | HEK293 |
Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL an... | |||
TMPY-00362 | Cathepsin S Protein, Rat, Recombinant (His) | Rat | HEK293 |
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS... | |||
TMPY-00733 | Cathepsin D Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly... | |||
TMPY-04081 | Cathepsin H Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. | |||
TMPY-00055 | LCAT Protein, Human, Recombinant (His) | Human | HEK293 |
Lecithin: cholesterol acyltransferase (LCAT) is the sole enzyme that esterifies cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol gradie... | |||
TMPH-00060 | ApNPV Viral cathepsin Protein (His & Myc) | ApNPV | E. coli |
Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. | |||
TMPH-00875 | ACAT1 Protein, Human, Recombinant (His) | Human | E. coli |
This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleava... | |||
TMPH-01060 | Cathepsin F Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | |||
TMPH-00056 | Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His) | Anemonia sulcata | Yeast |
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent... | |||
TMPH-00437 | Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) | Chinese hamster | E. coli |
Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-02554 | BCAT2 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. | |||
TMPH-03186 | Metapyrocatechase Protein, Pseudomonas putida, Recombinant (His & Myc & SUMO) | Pseudomonas putida | E. coli |
Metapyrocatechase Protein, Pseudomonas putida, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-03263 | Cathepsin Z Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity. Capable of producing kinin potentiating peptides. | |||
TMPH-00026 | Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His) | Actinia equina | E. coli |
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphin... | |||
TMPH-01061 | Cathepsin K Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPH-00014 | Abrin-c Protein, Abrus precatorius, Recombinant (His & Myc) | Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.; The B chain... | |||
TMPH-02628 | Cathepsin C Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function. | |||
TMPH-01058 | Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. | |||
TMPH-03564 | MCAT Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
MCAT Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa. Accession number: Q5HGK3 | |||
TMPH-03563 | MCAT Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | Yeast |
MCAT Protein, S. aureus, Recombinant (His) is expressed in Yeast with N-terminal 6xHis tag. The predicted molecular weight is 35.6 kDa. Accession number: Q5HGK3 | |||
TMPK-00835 | LCAT Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Lecithin:cholesterol acyltransferase (LCAT) is the only enzyme capable of esterifying cholesterol in plasma, thus determining the maturation of high-density lipoproteins. Because it maintains an unesterified cholesterol ... | |||
TMPY-01699 | Cathepsin E Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Cathepsin E Protein (CTSE Protein) is a member of the peptidase C1 family that is a gastric aspartic protease that functions as a disulfide-linked homodimer. Cathepsin E Protein (CTSE Protein) is predominantly present in... | |||
TMPY-06479 | Cathepsin H Protein, Human, Recombinant (His) | Human | HEK293 |
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. | |||
TMPY-01249 | Cathepsin V Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t... | |||
TMPY-00439 | Cathepsin E Protein, Rat, Recombinant (His) | Rat | HEK293 |
Cathepsin E Protein (CTSE Protein) is a member of the peptidase C1 family that is a gastric aspartic protease that functions as a disulfide-linked homodimer. Cathepsin E Protein (CTSE Protein) is predominantly present in... | |||
TMPH-00484 | Cationic trypsin Protein, Canine, Recombinant (His & SUMO) | Canine | E. coli |
Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01059 | Cathepsin B Protein, Human, Recombinant (GST) | Human | E. coli |
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobuli... | |||
TMPH-00058 | AsFP595 Protein, Anemonia sulcata, Recombinant (hFc) | Anemonia sulcata | HEK293 |
Pigment protein that is intensely purple in color. | |||
TMPH-00015 | Abrin-d Protein, Abrus precatorius, Recombinant (His & Myc) | Abrus precatorius | E. coli |
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.; The B chain is a galactose-specific lectin th... | |||
TMPH-03262 | Cathepsin K Protein, Rat, Recombinant (His) | Rat | E. coli |
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in... | |||
TMPH-00057 | AsFP595 Protein, Anemonia sulcata, Recombinant (GST) | Anemonia sulcata | E. coli |
Pigment protein that is intensely purple in color. | |||
TMPH-01062 | Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli |
Proteolytic enzyme possibly involved in normal cellular protein degradation and turnover. | |||
TMPH-02565 | Cathepsin K Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thy... | |||
TMPY-00732 | Cathepsin C Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also kno... | |||
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Cat No. | Product Name | ||
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L3500 | Histone Modification Compound Library | 480 compounds | |
A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L8300 | Chromatin Modification Compound Library | 256 compounds | |
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); |