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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

Search Result

Search Results for "cat"

Targets

Wnt/beta-catenin CAT advanced glycation end products

Libraries

Histone Modification Compound Library Chromatin Modification Compound Library
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Compounds

Cat No. Product Name
T15198 Edasalonexent CAT-1004 NF-κB
Edasalonexent is an orally bioavailable inhibitor of NF-κB.
T2856 (-)-Epicatechin L-Epicatechin,Epicatechin,(-)-Epicatechol,表儿茶精,表儿茶素 Ferroptosis , Endogenous Metabolite , COX
(-)-Epicatechin 是一种 COX-1 的抑制剂，通过阻断 NF-κB 的 p65 亚基的核定位来抑制 IL-1β 诱导的 iNOS 表达。
T3682 (-)-Catechin gallate 儿茶素没食子酸酯,几茶素没食子酸酯,(-)-Catechin 3-gallate,(-)-Catechin 3-O-gallate Others , COX
(-)-Catechin gallate 是绿茶儿茶素中的微量组分，可抑制COX-1和COX-2活性。它抑制人 Beta-secretase，对氯喹敏感的恶性疟原虫 NF54 和耐氯喹的恶性疟原虫 K1 具有抗疟原虫活性。
T1239 Indacaterol maleate QAB149,马来酸茚达特罗 Adrenergic Receptor
Indacaterol maleate 是一种超长效的 β-肾上腺素受体激动剂。
TP1730L β-catenin peptide acetate(265669-37-2 free base) Others
β-catenin peptide acetate(265669-37-2 free base) 是一种由 Kb 呈递的天然存在的自身肽，可非常有效地介导 OT-I 胸腺细胞的阳性选择。
T1742 4E1rcat Autophagy , PERK
4E1RCat 是 cap 依赖性翻译抑制剂，可抑制 eIF4 g 与 eIF4E 的结合，IC50 为 3.2 μM。
T2782 Catharanthine (+)-3, 4-Didehydrocoronaridine,(+)-3,4-Didehydrocoronaridine,长春质碱 AChR , Calcium Channel
Catharanthine 是长春花中的一种生物碱，可抑制电压门控 L 型钙离子通道，具有抗肿瘤和降血压活性。
T5132 9-dihydro-13-acetylbaccatin III 9-DHAB III,13-Acetyl-9-dihydrobaccatin III,13-乙酰基-9-羟基巴卡丁 III Apoptosis
9-Dihydro-13-acetylbaccatin III 是一种制备紫杉醇类似物的中间体。
T9065 4-Isopropylcatechol Others
4-Isopropylcatechol 是一种有效的脱色剂，可用于特定黑色素沉着症患者的局部治疗。
T2320 Indacaterol Adrenergic Receptor
Indacaterol 是一种超长效β-肾上腺素受体激动剂。
TN7047 6-O-Methylcatalpol Others
6-O-Methylcatalpol 是从 S. ningpoensis 的根中分离得到的天然产物。
T23109 3,5-Dinitrocatechol Transferase
3,5-Dinitrocatechol 是儿茶酚-O-甲基转移酶的有效抑制剂，IC50为 12 nM。它可用于制备钼 (VI)- 3,5-Dinitrocatechol 配合物。
TQ0038 Brensocatib AZD7986,INS 1007 Proteasome
AZD7986 是一种二肽基肽酶 1 (DPP1) 抑制剂，在人，小鼠，大鼠，狗和兔中的pIC50分别为 6.85, 7.6, 7.7, 7.8 和 7.8。
TN7036 N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide 间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14,(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide Wnt/beta-catenin
N-3-methoxylBenzyllinolenicamide 是一种从玛卡中分离得到的玛卡酰胺。它能够激活典型的Wnt/β‐catenin 信号通路，诱导间充质干细胞成骨分化和随后的骨形成，可用于研究骨质疏松症。
T3023 Catharanthine sulfate AChR
Catharanthine sulfate 抑制烟碱样受体介导的隔膜收缩。
T2988 (-)-Epigallocatechin Gallate (-)-表没食子儿茶素没食子酸酯,EGCG,Epigallocatechol Gallate Ferroptosis , Autophagy , Endogenous Metabolite , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism
(-)-Epigallocatechin Gallate 是茶类黄酮，具有强大的抗氧化，抗炎和抗癌作用。它可抑制EGFR 信号传导，有抗癌作用。它是谷氨酸脱氢酶 1/2 抑制剂。它通过激活细胞色素c 氧化酶来诱导氧化磷酸化。
T4779 4-Methylcatechol 3,4-二羟基甲苯,p-Methylcatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene,Homocatechol Others , Endogenous Metabolite
4-Methylcatechol 是 p-toluate 的代谢物，它是 Catechol 2,3-Dioxygenase 的自杀性底物抑制剂。
T2782L Catharanthine Tartrate(2468-21-5(free base)) Calcium Channel
Catharanthine Tartrate(2468-21-5(free base)) 是从马达加斯加长春花中分离得到的天然产物，Catharanthine Tartrate 抑制电压操作的L 型Ca2+通道，具有抗癌和降血压活性。
T41094 Wnt/β-catenin agonist 2 Wnt/beta-catenin , GSK-3
Wnt/β-catenin agonist 2激活 Wnt/β-catenin 信号传导，是一种有效的 Wnt 激动剂。 Wnt/β-catenin agonist 2可用于与信号转导相关的疾病研究，与癌症侵袭转移密切相关。
T60812 Cathepsin X-IN-1 Cysteine Protease
Cathepsin X-IN-1 (compound 25) 降低人前列腺癌细胞 PC-3 的迁移且具有较低的细胞毒性，它是组织蛋白酶 X 的有效抑制剂 (IC50 = 7.13 μM)。
Edasalonexent
T15198
synonym: CAT-1004
Target:
(-)-Epicatechin
T2856
synonym: L-Epicatechin,Epicatechin,(-)-Epicatechol,表儿茶精,表儿茶素
Target:
(-)-Catechin gallate
T3682
synonym: 儿茶素没食子酸酯,几茶素没食子酸酯,(-)-Catechin 3-gallate,(-)-Catechin 3-O-gallate
Target:
Indacaterol maleate
T1239
synonym: QAB149,马来酸茚达特罗
Target:
β-catenin peptide acetate(265669-37-2 free base)
TP1730L
synonym:
Target:
4E1rcat
T1742
synonym:
Target:
Catharanthine
T2782
synonym: (+)-3, 4-Didehydrocoronaridine,(+)-3,4-Didehydrocoronaridine,长春质碱
Target:
9-dihydro-13-acetylbaccatin III
T5132
synonym: 9-DHAB III,13-Acetyl-9-dihydrobaccatin III,13-乙酰基-9-羟基巴卡丁 III
Target:
4-Isopropylcatechol
T9065
synonym:
Target:
Indacaterol
T2320
synonym:
Target:
6-O-Methylcatalpol
TN7047
synonym:
Target:
3,5-Dinitrocatechol
T23109
synonym:
Target:
Brensocatib
TQ0038
synonym: AZD7986,INS 1007
Target:
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
TN7036
synonym: 间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14,(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide
Target:
Catharanthine sulfate
T3023
synonym:
Target:
(-)-Epigallocatechin Gallate
T2988
synonym: (-)-表没食子儿茶素没食子酸酯,EGCG,Epigallocatechol Gallate
Target:
4-Methylcatechol
T4779
synonym: 3,4-二羟基甲苯,p-Methylcatechol,4-methylbenzene-1,2-diol,3,4-Dihydroxytoluene,Homocatechol
Target:
Catharanthine Tartrate(2468-21-5(free base))
T2782L
synonym:
Target:
Wnt/β-catenin agonist 2
T41094
synonym:
Target:
Cathepsin X-IN-1
T60812
synonym:
Target:
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