trim

TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.

Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite derived from dietary choline, betaine, and carnitine. It induces inflammation by activating the ROS/NLRP3 inflammasome and promotes fibroblast differentiation through the activation of the TGF-β/Smad2 signaling pathway. TMAO is commonly used to induce cardiac fibrosis models.

Trimebutine CTB salt (GIC-1001) is an opioid receptor agonist used in the study of pain.

Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate) is a chemical compound that is a phosphate derivative of the statin class.

TRIM24/BRPF1-IN-2 is a selective dual TRIM24/BRPF1 inhibitor with anticancer activity that inhibits proliferation, gene and protein expression, and colony formation of prostate cancer cells in a dose-dependent manner.

(E)-1,7,7-trimethyl-3-((3-(trifluoromethyl)phenyl)imino)bicyclo[2.2.1]heptan-2-one is a useful organic compound for research related to life sciences and the catalog number is T9539.

Piperazine,1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]- is a piperazine derivative with anti-SARS-CoV-2 activity.

3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).

Compound Fr14500 is a natural product for research related to life sciences. The catalog number is Fr14500 and the CAS number is 14667-55-1.

4-AMino-1,3,5-triMethylpyrazole, with CAS No. 28466-21-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-AMino-1,3,5-triMethylpyrazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Trimethadione (3,5,5-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.

Cetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.

Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.

2,3,4-Trimethoxybenzaldehyde (Trimethoxybenzaldehyde) is used as medicine intermediate.

Trimethylacetic anhydride (Pivalic anhydride) is used as medical intermediate

Methyl EudesMate, synthesized from Gallic acid, has antioxidant activity and is commonly used in the production of sulfonamide synergist intermediates, trimethoprim (TMP) and many other drugs.

3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice. It also exerts hepatoprotective effects in CCl4-induced rats, specifically by modulating oxidative-nitrosative stress and inflammation.

Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders. It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. Trimebutine is not an FDA-Approved/Clinical drug, but it is available in Canada and several other international countries.

Trimetazidine dihydrochloride (Vastarel F) can improve myocardial glucose utilization by inhibiting fatty acid metabolism. Trimetazidine is the first cytoprotective anti-ischemic agent, also used as a vasodilator in ischemic heart disease or angina.

Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Maleate is the maleate salt form of trimipramine, a tricyclic secondary amine of the dibenzazepine class, with an antidepressant property.

Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.

Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors served as a spasmolytic drug for therapy of both chronic and acute abdominal pain.

Trioctyl trimellitate is a viscous tricarboxylate used in organic synthesis and biochemical experiments.

1,5,5-Trimethylhydantoin (TMH) serves as a non-isotopic internal standard (IS).