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Search Results for " antimalarial "

Targets

154

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T10336	Antimalarial agent 1		Parasite
	Antimalarial agent 1 is an effective antimalarial agent.		Parasite
T9984	Antimalarial agent 13	N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine	Parasite
	Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.		Parasite
T22381	Antimalarial agent 14	4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone	Others
	Antimalarial agent 14 (NSC-102533) is a bioactive chemical.		Others
T79535	Antimalarial agent 30		Parasite
	Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.		Parasite
T61200	Antimalarial agent 3
	Antimalarial agent 3, an antimalarial agent, exhibits potent activity against Plasmodium with an IC50 of 0.035 μM. Furthermore, it demonstrates an exceptionally high selectivity index in relation to mammalian cells.
T63456	Antimalarial agent 12
	Antimalarial agent 12 is an effective antimalarial agent that inhibits the growth of Plasmodium falciparum strains Dd2 and 3D7 with EC50 values of 155 nM and 136 nM, respectively. antimalarial agent 12 has a MIC >250,000...
T63052	Antimalarial agent 10
	Antimalarial agent 10 (Compound 17b) is an amino alcohol-quinoline compound. Antimalarial agent 10 is also an antimalarial agent capable of acting on Pf3D7 (IC50: 14.9 nM) and PfW2 (IC50: 11 nM) with a selectivity index ...
T63413	Antimalarial agent 15
	Antimalarial agent 15 is a parasite inhibitor that exhibits antimalarial effects and inhibits the growth of Plasmodium falciparum 3D7 with an IC50 value of 20 nM.
T74695	Antimalarial agent 17
	Antimalarial agent 17, functioning both as an antimalarial agent and a herbicide, inhibits photosystem II and demonstrates post-emergence herbicidal efficacy comparable to commercial herbicides [1].
T83044	Antimalarial agent 33		Parasite
	Antimalarial agent 33 (compound 5g) exhibits antiplasmodial activity targeting both erythrocytic and hepatic stages of Plasmodium, with an effective concentration (EC50) of 1.1 μM against the K1 strain of P. falciparum. ...		Parasite
T79460	Antimalarial agent 28		Parasite
	Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P. berghei with IC50 values of 0.561 μM for the liver stage, 0.14 μM for early gametocytes, and 4.34 μM for the ring stages of...		Parasite
T78936	Antimalarial agent 27		Parasite
	Antimalarial agent 27 (compound 11a) potently inhibits P. falciparum with an IC50 of 0.37 μM and targets the parasite's 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) enzyme with an IC50 of 0.11 μM, indicating its...		Parasite
T63043	Antimalarial agent 2
	Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.
T72396	Antimalarial agent 20
	Antimalarial agent 20, exhibiting potent efficacy with an IC50 value of 0.6 nM against the P. falciparum NF54 parasite strain within the NF54 albumax assay, serves as a significant antimalarial compound.
T62936	Antimalarial agent 8
	Antimalarial agent 8 (Compound 7e) is a novel, orally active antimalarial agent that is effective against P. falciparum in vitro and effective orally in an in vivo mouse model of malaria (40 mg/kg).
T78952	Antimalarial agent 26		Parasite
	Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration. It exhibits cytotoxic effects on P. falciparum while maintaining selectivity against mammalian...		Parasite
T72416	Antimalarial agent 18
	Antimalarial agent 18, a powerful antimalarial compound characterized by its electronic, highly lipophilic, and siderophoric properties, falls within the acyloxymethyl series, acting as a fosmidomycin surrogate. It effec...
T62300	Antimalarial agent 11
	Antimalarial agent 11 (compound 1) is a potent antimalarial agent, a spirocyclic chromane. Antimalarial agent 11 is able to act on D6 (EC50: 1.48 μM) and ARC08-022 (EC50: 1.81 μM).
T63655	Antimalarial agent 9
	Antimalarial agent 9 is an effective antimalarial agent, a quinoline-imidazole derivative compound. antimalarial agent 9 showed significant in vitro antimalarial effects against CQ-susceptible strains (IC50-0.14 μM) and ...
T62537	Antimalarial agent 7
	Antimalarial agent 7 is a potent and effective inhibitor of PfATP4. Antimalarial agent 7 has potential for the study of the human plasmodium falciparum.
T63595	Antimalarial agent 16
	Antimalarial agent 16 is a parasite inhibitor that exhibits antimalarial effects and inhibits the growth of Plasmodium falciparum with an IC50 value of 2.0 nM.
T79335	Antimalarial agent 31		Parasite
	Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].		Parasite
T75067	Antimalarial agent 19		Parasite
	Antimalarial agent 19 (compound 6e) exhibits antimalarial activity against the blood stages of P. falciparum K1 and P. berghei, with EC50 values of 0.3 µM and 15.3 µM, respectively. It demonstrates good aqueous solubilit...		Parasite
T74845	Antimalarial agent 23
	Antimalarial agent 23, a benzimidazole-based compound, exhibits potent antimalarial activity, demonstrated by its low IC50 values of 0.08 μM for PfNF54 and 0.10 μM for PfK1, respectively. This compound effectively inhibi...
T78951	Antimalarial agent 24		Parasite
	Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM and exhibits a cytotoxicity threshold (CC50) exceeding 200 μM...		Parasite
T79534	Antimalarial agent 29		Parasite
	Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P. berghei liver stage parasite load, exhibiting an effective concentration (EC50) of 5.2 μM [1].		Parasite
T9741	INE963		Others
	INE963 demonstrates potent cellular activity against Pf 3D7 (EC50 = 6 nM) and achieves "artemisinin-like" kill kinetics in vitro with a parasite clearance time of <24 h. INE963 is also potent against P. falciparum and P....		Others
T8381	Amodiaquine		Others , Histone Methyltransferase , Parasite
	Amodiaquine is a synthetic aminoquinoline, used to treat malaria.		Others , Histone Methyltransferase , Parasite
T5477	ELQ-300		Parasite
	ELQ-300 is bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1)		Parasite
T6992	Sulfadiazine sodium	Sulfadiazin-natrium,Sodium sulfadiazine	Others , Antibacterial , Antibiotic , Parasite
	Sulfadiazine sodium (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.		Others , Antibacterial , Antibiotic , Parasite
T4382	Proguanil hydrochloride	Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil	Others , Dehydrogenase , DNA/RNA Synthesis , Antifolate , Parasite
	Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine ...
T40417	Ethylhydrocupreine hydrochloride	Optochin hydrochloride	Antibacterial , Parasite
	Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a derivative of quinine with antimicrobial activity against Streptococcus pneumoniae.Ethylhydrocupreine hydrochloride has antimalarial activity with an IC50 of...		Antibacterial , Parasite
T0849	Pyrimethamine	Pirimecidan,RP 4753,Pirimetamin	DHFR , Antifolate , Parasite
	Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.		DHFR , Antifolate , Parasite
T11558	Hexyl gallate	Gallic acid hexyl ester,Hexyl 3,4,5-trihydroxybenzoate	Antibacterial
	Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).		Antibacterial
T0860	Mefloquine hydrochloride	Mefloquin hydrochloride,Mefloquine HCl	Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy
	Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
T7744	Piperaquine tetraphosphate tetrahydrate		Parasite
	Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent.		Parasite
T0381	Amodiaquine dihydrochloride dihydrate	Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate	Histone Methyltransferase , Parasite , Histamine Receptor
	Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.		Histone Methyltransferase , Parasite , Histamine Receptor
T7532	Piperaquine		Parasite
	Piperaquine is a bis-quinoline compound that inhibits the ex vivo growth of P. falciparum isolates from malaria-infected patients with IC50s ranging from 11.8-217.3 nM.		Parasite
T0860L	Mefloquine	Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998	Others
	Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l...		Others
T6888	Methylene Blue	methylthioninium chloride,CI-52015,Tetramethylthionine chloride,Basic Blue 9	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
T0006	Methylene Blue trihydrate	Methylthionine chloride,Basic blue 9,Methylene Blue	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate...
T10378	Artelinic acid		Others
	Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug-resistant strains of Plasmodium falciparum.		Others
T67695	MMV688533		Parasite
	MMV688533 has antimalarial activity.		Parasite
T20102	8-Azahypoxanthine	NSC 22709,NSC-22709,NSC22709	Nucleoside Antimetabolite/Analog
	8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.		Nucleoside Antimetabolite/Analog
T17313	(+)-SJ733	SJ000557733	ATPase , Parasite
	(+)-SJ733 (SJ000557733) is a potent Na+-ATPase PfATP4 inhibitor with antimalarial activity for the study of malaria.		ATPase , Parasite
T9591	YCN47284		Parasite
	YCN47284 is an antimalarial compound with an IC50 of 1 μM for P. falciparum.		Parasite
T0519	Euquinine	Quinine ethylcarbonate	Others
	Euquinine (Quinine ethylcarbonate) generally is served as the febrifuge, antimalarial, and tonic.		Others
T80665	Leu-Val	L-leucyl-L-valine	Parasite , Antifungal
	Leu-Val (L-leucyl-L-valine) is a novel potent dipeptide with antibacterial and antimalarial activity.		Parasite , Antifungal
T16326	Cipargamin	KAE609,NITD609	Parasite
	Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum.		Parasite
T10356	AQ-13 dihydrochloride		Parasite
	AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.		Parasite

Compounds

Antimalarial agent 1

T10336

Synonym:

Target: Parasite

Antimalarial agent 13

T9984

Synonym: N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine

Target: Parasite

Antimalarial agent 14

T22381

Synonym: 4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone

Target: Others

Antimalarial agent 30

T79535

Synonym:

Target: Parasite

Antimalarial agent 3

T61200

Synonym:

Target:

Antimalarial agent 12

T63456

Synonym:

Target:

Antimalarial agent 10

T63052

Synonym:

Target:

Antimalarial agent 15

T63413

Synonym:

Target:

Antimalarial agent 17

T74695

Synonym:

Target:

Antimalarial agent 33

T83044

Synonym:

Target: Parasite

Antimalarial agent 28

T79460

Synonym:

Target: Parasite

Antimalarial agent 27

T78936

Synonym:

Target: Parasite

Antimalarial agent 2

T63043

Synonym:

Target:

Antimalarial agent 20

T72396

Synonym:

Target:

Antimalarial agent 8

T62936

Synonym:

Target:

Antimalarial agent 26

T78952

Synonym:

Target: Parasite

Antimalarial agent 18

T72416

Synonym:

Target:

Antimalarial agent 11

T62300

Synonym:

Target:

Antimalarial agent 9

T63655

Synonym:

Target:

Antimalarial agent 7

T62537

Synonym:

Target:

Antimalarial agent 16

T63595

Synonym:

Target:

Antimalarial agent 31

T79335

Synonym:

Target: Parasite

Antimalarial agent 19

T75067

Synonym:

Target: Parasite

Antimalarial agent 23

T74845

Synonym:

Target:

Antimalarial agent 24

T78951

Synonym:

Target: Parasite

Antimalarial agent 29

Target: Others, Histone Methyltransferase, Parasite

Synonym: Sulfadiazin-natrium,Sodium sulfadiazine

Target: Others, Antibacterial, Antibiotic, Parasite

Proguanil hydrochloride

T4382

Synonym: Paludrine hydrochloride,Chlorguanide hydrochloride,Chloroquanil

Target: Others, Dehydrogenase, DNA/RNA Synthesis, Antifolate, Parasite

Ethylhydrocupreine hydrochloride

T40417

Synonym: Optochin hydrochloride

Target: Antibacterial, Parasite

Pyrimethamine

T0849

Synonym: Pirimecidan,RP 4753,Pirimetamin

Target: DHFR, Antifolate, Parasite

Hexyl gallate

T11558

Synonym: Gallic acid hexyl ester,Hexyl 3,4,5-trihydroxybenzoate

Target: Antibacterial

Mefloquine hydrochloride

T0860

Synonym: Mefloquin hydrochloride,Mefloquine HCl

Target: Potassium Channel, SARS-CoV, Reactive Oxygen Species, Parasite, Autophagy

Piperaquine tetraphosphate tetrahydrate

T7744

Synonym:

Target: Parasite

Amodiaquine dihydrochloride dihydrate

T0381

Synonym: Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate

Target: Histone Methyltransferase, Parasite, Histamine Receptor

Synonym: Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998

Target: Others

Methylene Blue

T6888

Synonym: methylthioninium chloride,CI-52015,Tetramethylthionine chloride,Basic Blue 9

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Methylene Blue trihydrate

T0006

Synonym: Methylthionine chloride,Basic blue 9,Methylene Blue

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Synonym: NSC 22709,NSC-22709,NSC22709

Target: Nucleoside Antimetabolite/Analog

(+)-SJ733

T17313

Synonym: SJ000557733

Target: ATPase, Parasite

Synonym: Quinine ethylcarbonate

Target: Others

Leu-Val

T80665

Synonym: L-leucyl-L-valine

Target: Parasite, Antifungal

Cipargamin

T16326

Synonym: KAE609,NITD609

Target: Parasite

AQ-13 dihydrochloride

T10356

Synonym:

Target: Parasite

Cat No.	Product Name	Synonyms	Targets
T6S0084	Tuberostemonine	Tuberstemonine	Parasite
	1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction.		Parasite
T10835	Cletoquine	Desethylhydroxychloroquine	Parasite , Antifection
	Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatme...		Parasite , Antifection
TN2027	Oxysanguinarine	8-Oxosanguinarine,Hydroxysanguinarine	Parasite
	Oxysanguinarine (Hydroxysanguinarine) possesses antiplatelet aggregation activity, it has potential inhibitory properties against the dengue virus.		Parasite
TN1019	Beta-mangostin	β-Mangostin	Apoptosis , Antibacterial , Parasite
	Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo...		Apoptosis , Antibacterial , Parasite
TN1012	Febrifugine		IL Receptor , Anti-infection , Parasite
	Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity .		IL Receptor , Anti-infection , Parasite
TN1012L	Febrifugine dihydrochloride	ISF-2123,Propyldazine hydrochloride,Atensil,(+)-Febrifugine dihydrochloride,Pildralazine dihydrochloride	Parasite
	Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.		Parasite
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T3S1447	Arteannuin B		SARS-CoV , Ferroptosis
	1. Arteannuin B has potent antimalarial activity.		SARS-CoV , Ferroptosis
T7059	α-Dihydroartemisinin	α-Artenimol,α-Dihydroqinghaosu	Parasite
	α-Dihydroartemisinin (α-Dihydroqinghaosu) is an intermediate of artemisinin-based antimalarial compounds with good antimalarial and anticancer activity, and can be used in the study of lupus erythematosus.		Parasite
T25114	Ascaridole	NSC-406266,NSC 406266,NSC406266	Parasite
	Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity.		Parasite
T1323	Artemether	SM224,Dihydroartemisinin methyl ether,Dihydroqinghaosu methyl ether,CGP 56696	Antibiotic , Parasite
	Artemether (CGP 56696) is an antimalarial agent used to treat acute uncomplicated malaria.		Antibiotic , Parasite
T3327	Artemotil	SM-227,β-Arteether,Beta-Arteether,Arteether,(+)-Arteether	CXCR , CCR , Parasite
	Artemotil (SM-227) is a new, fast-acting antimalarial drug.		CXCR , CCR , Parasite
TN1145	Isofebrifugine		Parasite
	Isofebrifugine is an alkaloid from the plant Changshan of the Saxifrage family with antimalarial and anti-infectious activity.		Parasite
T3819	Ursolic acid acetate	Acetylursolic acid,3-Acetylursolic Acid	AChE
	Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition ...		AChE
T4333	Quinine dihydrochloride	Quinine bimuriate	Others
	Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).		Others
T7938	Quinidine		Parasite
	Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.		Parasite
T0194	Chloroquine phosphate	Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate	SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy
	Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs).
T21065	Artemisitene		Others
	Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini...		Others
TN1100	Nepodin		transporter , COX , AMPK , Parasite
	Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, which is at least partly mediated by stimulation of GLUT4 tra...		transporter , COX , AMPK , Parasite
T8859	NITIDINE		Others
	Nitidine is a bioactive plant benzophenanthridine alkaloid isolated from the root of Zanthoxylum nitidum. It shows anticancer, neuroprotective, antimalarial, anti-HIV, analgesic, anti-inflammatory and antifungal activiti...		Others
T2830	Betulinic acid	ALS-357,Lupatic acid,Betulic acid	Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy
	Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert...
TN1393	(-)-Anonaine		Apoptosis , Antioxidant , Parasite , Antifungal
	(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces ...		Apoptosis , Antioxidant , Parasite , Antifungal
TN4883	Quinine sulfate dihydrate		Others
	Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...		Others
T3417	Amentoflavone	Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin	Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
TN2254	Taccalonolide A		Apoptosis , Microtubule Associated
	Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these ...		Apoptosis , Microtubule Associated
TN5937	Walsuronoid B
	Walsuronoid B shows weak antimalarial activity.
TN4276	Isocudraniaxanthone B		Sodium Channel , Antifection
	Isocudraniaxanthone B may have antimalarial activity.		Sodium Channel , Antifection
TN4275	Isocudraniaxanthone A		Antifection
	Isocudraniaxanthone A may have antimalarial activity.		Antifection
TN4229	Humulene epoxide II		Antifection
	Humulene epoxide II has antimalarial activity.		Antifection
TN4314	Isonardoperoxide		Antifection
	Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10-7 M).		Antifection
TN3452	Arteannuin M		TNF , Antifection
	Arteannuin M has antimalarial activity. It can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation.		TNF , Antifection
TN3583	Canophyllal		Antifection
	Canophyllal shows antiplasmodial activity against the W2 strain of Plasmodium falciparum which is resistant to chloroquine and other antimalarial drugs.		Antifection
T12517	Polyketomycin		Others
	Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes, has antibacterial, anticancer, antimalarial activities.		Others
TN3427	Aphadilactone B		Antifection
	Aphadilactone B shows significant antimalarial activity with the IC50 value of 1350 ± 150 nM.		Antifection
TN4535	Methyl 6-acetoxyangolensate		Antifection
	Methyl-6-acetoxy angolensate may have antimalarial activity.		Antifection
TN3453	Arteannuin N		TNF , Antifection
	Arteannuin N has antimalarial activity. It can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation.		TNF , Antifection
T11534	Haemanthamine		Others
	Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiv...		Others
TN4666	Norcaesalpinin E		Antifection
	Norcaesalpinin E shows antimalarial activity against the malaria parasite Plasmodium falciparum FCR-3/A2 clone in vitro, with an IC50 value of 0.090 microM.		Antifection
T79997	(±)-Emodin bianthrone		Parasite
	(±)-Emodin bianthrone (compound 10), a naturally occurring substance, demonstrates antimalarial, antitubercular, and antifungal properties [1].		Parasite
TN2738	2,6-Dimethoxy-1-acetonylquinol		Antifection
	2,6-Dimethoxy-1-acetonylquinol shows varying degrees of in vitro antimalarial activity against Plasmodium falciparum. It is devoid of significant cytotoxicity to the human oral epidermoid KB cancer cell line.		Antifection
TN4733	Pancixanthone A		Antifection
	Pancixanthone A may have antimalarial activity, it also shows a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and against the amastigote forms of L. infantum.		Antifection
TN3799	Dehydrocrebanine		Antifection
	Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml.		Antifection
TN3422	Anisofolin A		Antifection
	Anisofolin A has promising antimalarial activity (IC50 4.39 ± 0.25 uM). It has promising antimycobacterium activity [IC50 4.50 ± 0.75 uM (3.31 ug/mL)] against M. tuberculosis H37Ra and at 100 ug/mL, shows 55.6 % inhibiti...		Antifection
T40643	Prodigiosin hydrochloride	Prodigiosine hydrochloride
	Prodigiosin hydrochloride, a red pigment, is a bioactive secondary metabolite produced by bacteria. It exhibits potent proapoptotic activity and functions as an inhibitor of the Wnt/β-catenin pathway. Additionally, this ...
TN3428	Aphadilactone C		Others
	Aphadilactone C shows significant antimalarial activity with the IC50 value of 170 ± 10 nM. It shows potent and selective inhibition against the diacylglycerol O-acyltransferase-1 (DGAT-1) enzyme (IC50 = 0.46 ± 0.09 uM, ...		Others
T75663	7-Methoxy-β-carboline-1-propionic acid
	7-Methoxy-β-carboline-1-propionic acid (compound 46), known for its cytotoxic and antimalarial properties, is derived from the roots of Eurycoma longifolia [1].
TN1349	9-Hydroxycalabaxanthone		Antifection
	9-Hydroxycalabaxanthone exhibits cytotoxicity against the HT-29 cell line with ED50 values of 9.1 microM. The combination of 9-hydroxycalabaxanthone with α±-mangostin shows the synergistic antimalarial interaction in bot...		Antifection
TN2567	10-Hydroxycanthin-6-one		Antifection
	10-Hydroxycanthin-6-one has potential to be an antimicrobial agent. 10-Hydroxycanthin-6-one has in vitro antimalarial activity; it also has cytotoxic activity, it could be a plant anticancer agent.		Antifection
TN6107	3β-Isodihydrocadambine		Antioxidant , Parasite
	3β-Isodihydrocadambine is a cadambine derivative that can be extracted from the bark and leaves of Neolamarckia cadamba. 3β-Isodihydrocadambine has antimalarial, antiproliferative, antioxidant, anticancer and anti-inflam...		Antioxidant , Parasite
TN6014	Norcepharadione B
	Norcepharadione B shows good inhibitory activity against the replication of HSV-1, it also shows antimalarial activity with EC50 values of 7.5mug/ml. Norcepharadione B exhibits significant cytotoxicity against five human...
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Natural Products

Tuberostemonine

T6S0084

Synonym: Tuberstemonine

Target: Parasite

Cletoquine

T10835

Synonym: Desethylhydroxychloroquine

Target: Parasite, Antifection

Oxysanguinarine

TN2027

Synonym: 8-Oxosanguinarine,Hydroxysanguinarine

Target: Apoptosis, Antibacterial, Parasite

Febrifugine

TN1012

Synonym:

Target: IL Receptor, Anti-infection, Parasite

Febrifugine dihydrochloride

TN1012L

Synonym: ISF-2123,Propyldazine hydrochloride,Atensil,(+)-Febrifugine dihydrochloride,Pildralazine dihydrochloride

Target: Parasite

Lycorine

T3324

Synonym: Galanthidine,Narcissine,Amarylline,Belamarine,Licorine

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Arteannuin B

T3S1447

Synonym:

Target: SARS-CoV, Ferroptosis

α-Dihydroartemisinin

T7059

Synonym: α-Artenimol,α-Dihydroqinghaosu

Target: Parasite

Ascaridole

T25114

Synonym: NSC-406266,NSC 406266,NSC406266

Target: Parasite

Artemether

T1323

Synonym: SM224,Dihydroartemisinin methyl ether,Dihydroqinghaosu methyl ether,CGP 56696

Target: Antibiotic, Parasite

Artemotil

T3327

Synonym: SM-227,β-Arteether,Beta-Arteether,Arteether,(+)-Arteether

Target: CXCR, CCR, Parasite

Synonym: Acetylursolic acid,3-Acetylursolic Acid

Target: AChE

Quinine dihydrochloride

T4333

Synonym: Quinine bimuriate

Chloroquine phosphate

T0194

Synonym: Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Target: transporter, COX, AMPK, Parasite

Synonym: ALS-357,Lupatic acid,Betulic acid

Target: Apoptosis, Mitophagy, NF-κB, HIV Protease, Topoisomerase, Endogenous Metabolite, Aminopeptidase, Autophagy

(-)-Anonaine

TN1393

Synonym:

Target: Apoptosis, Antioxidant, Parasite, Antifungal

Quinine sulfate dihydrate

Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin

Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal

Taccalonolide A

TN2254

Synonym:

Target: Apoptosis, Microtubule Associated

Isocudraniaxanthone B

TN4276

Synonym:

Target: Sodium Channel, Antifection

Isocudraniaxanthone A

Target: TNF, Antifection

Methyl 6-acetoxyangolensate

Target: TNF, Antifection

(±)-Emodin bianthrone

T79997

Synonym:

Target: Parasite

2,6-Dimethoxy-1-acetonylquinol

Prodigiosin hydrochloride

T40643

Synonym: Prodigiosine hydrochloride

7-Methoxy-β-carboline-1-propionic acid

T75663

Synonym:

Target:

9-Hydroxycalabaxanthone

TN1349

Synonym:

Target: Antifection

10-Hydroxycanthin-6-one

TN2567

Synonym:

Target: Antifection

3β-Isodihydrocadambine

TN6107

Synonym:

Target: Antioxidant, Parasite

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04180	PfLDH Protein, P. falciparum, Recombinant (His)	P. falciparum	E. coli
	Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR as...
TMPY-03509	TCTP/TPT1 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor protein, also known as TPT1, is a highly conserved protein among many eukaryotic organisms. Tumor protein is involved in a variety of cellular activities, including microtubule stabilization, calcium-binding activi...

PfLDH Protein, P. falciparum, Recombinant (His)

TMPY-04180

Species: P. falciparum

Expression System: E. coli

TCTP/TPT1 Protein, Human, Recombinant (His)

TMPY-03509

Species: Human

Expression System: E. coli

Cat No.	Product Name
L6110	Alkaloid Natural Product Library	468 compounds
	A unique collection of 468 natural alkaloids can be used for high throughput and high content screening；
L6810	Traditional Chinese Medicine Monomer Library	2771 compounds
	A unique collection of 2771 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism；
L6800	Chinese Pharmacopoeia Natural Product Library	2070 compounds
	A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study;

Libraries

Alkaloid Natural Product Library

L6110

Compounds: 468

Traditional Chinese Medicine Monomer Library

L6810

Compounds: 2771

Chinese Pharmacopoeia Natural Product Library

L6800

Compounds: 2070