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Aminoacyl tRNA synthetase-IN-3 (compound 36K3) is an inhibitor of lysyl-tRNA synthetase (PfLysRS) in Plasmodium falciparum with an IC50 value of 59.2 nM. It works by occupying the ATP and L-lysine binding sites of PfLysRS, thereby inhibiting its activity. This compound is a potential candidate for antimalarial drug development.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Aminoacyl tRNA synthetase-IN-3 (compound 36K3) is an inhibitor of lysyl-tRNA synthetase (PfLysRS) in Plasmodium falciparum with an IC50 value of 59.2 nM. It works by occupying the ATP and L-lysine binding sites of PfLysRS, thereby inhibiting its activity. This compound is a potential candidate for antimalarial drug development. |
| Formula | C26H36N8O5S |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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