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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76120 | Phospholipase D | ||
Phospholipase D (PLD), an enzyme within the phospholipase superfamily, is prevalent across bacteria, yeast, plants, animals, and viruses, serving roles in biochemical research. It catalyzes the hydrolysis of glycerophosp... | |||
T76182 | Phospholipase A2 | ||
Phospholipase A2 (PLA2), a heat-stable, calcium-dependent enzyme class member, catalyzes the hydrolysis at the sn-2 position of membrane glycerophospholipids, releasing arachidonic acid (AA). It is frequently utilized in... | |||
TN1064 | Aristolochic acid C | Others | |
Aristolochic acid C could as the larval feeding stimulants. | |||
T60043 | DPTIP | Phospholipase | |
DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM. | |||
T7280 | CAY10594 | Phospholipase | |
CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis. | |||
T15461 | Halopemide | Others , Phospholipase , Dopamine Receptor | |
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research. | |||
T16108 | ML349 | Others , Phospholipase | |
ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM). | |||
TQ0159 | U-73343 | U 73343 | Phospholipase |
U-73343 is an inactive analog of U-73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. It is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor... | |||
T4511 | ST271 | ST 271 | Phospholipase , Tyrosine Kinases |
ST271 is an effective protein tyrosine kinase (PTK) inhibitor. | |||
T8974 | ML-211 | Others | |
ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM) | |||
T6243 | U-73122 | U73122 | Phospholipase , Ferroptosis , Lipoxygenase |
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN. | |||
T9753 | LEI110 | Phospholipase | |
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT). | |||
TN1419 | Rhamnetin | beta-Rhamnocitrin | Others , Phospholipase |
Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2. | |||
T22391 | Omeprazole Sodium | P450 , Proton pump , Antibacterial , Autophagy | |
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive... | |||
T2907 | Tanshinone I | Tanshinone A | Phospholipase |
Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells. | |||
T3990 | AA26-9 | Phospholipase , Serine Protease | |
AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase. | |||
T6109 | Darapladib | SB-480848 | Phospholipase |
Darapladib (SB-480848)(IC50=0.25 nM) is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2). | |||
T3580 | FIPI | 5-Fluoro-2-indolyl deschlorohalopemide | Phospholipase , Autophagy |
FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell s... | |||
T8966 | ML-298 | ML298,CID53393915 | Phospholipase |
ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM). | |||
T3640 | GW4869 | GW554869A,GW 4869,GW69A | Phospholipase |
GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM). GW4869 also inhibits exosome synthesis/release and is commonly used in exosome-related studies. |