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Search Results for " phospholipase "

20

Compounds

Cat No. Product Name Synonyms Targets
T76120 Phospholipase D
Phospholipase D (PLD), an enzyme within the phospholipase superfamily, is prevalent across bacteria, yeast, plants, animals, and viruses, serving roles in biochemical research. It catalyzes the hydrolysis of glycerophosp...
T76182 Phospholipase A2
Phospholipase A2 (PLA2), a heat-stable, calcium-dependent enzyme class member, catalyzes the hydrolysis at the sn-2 position of membrane glycerophospholipids, releasing arachidonic acid (AA). It is frequently utilized in...
TN1064 Aristolochic acid C Others
Aristolochic acid C could as the larval feeding stimulants.
T60043 DPTIP Phospholipase
DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.
T7280 CAY10594 Phospholipase
CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.
T15461 Halopemide Others , Phospholipase , Dopamine Receptor
Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2). Halopemid is an antagonist of dopamine receptors. Halopemid can be used in psychotropic research.
T16108 ML349 Others , Phospholipase
ML349 is an inhibitor of LYPLA2 (IC50: 144 nM). ML349 is an effective and specific acyl protein thioesterase 2 (APT-2) inhibitor (Ki: 120 nM).
TQ0159 U-73343 U 73343 Phospholipase
U-73343 is an inactive analog of U-73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. It is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor...
T4511 ST271 ST 271 Phospholipase , Tyrosine Kinases
ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
T8974 ML-211 Others
ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)
T6243 U-73122 U73122 Phospholipase , Ferroptosis , Lipoxygenase
U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.
T9753 LEI110 Phospholipase
LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).
TN1419 Rhamnetin beta-Rhamnocitrin Others , Phospholipase
Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities. Rhamnetin inhibits secretory phospholipase A2.
T22391 Omeprazole Sodium P450 , Proton pump , Antibacterial , Autophagy
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive...
T2907 Tanshinone I Tanshinone A Phospholipase
Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells.
T3990 AA26-9 Phospholipase , Serine Protease
AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
T6109 Darapladib SB-480848 Phospholipase
Darapladib (SB-480848)(IC50=0.25 nM) is a substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2).
T3580 FIPI 5-Fluoro-2-indolyl deschlorohalopemide Phospholipase , Autophagy
FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell s...
T8966 ML-298 ML298,CID53393915 Phospholipase
ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM).
T3640 GW4869 GW554869A,GW 4869,GW69A Phospholipase
GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM). GW4869 also inhibits exosome synthesis/release and is commonly used in exosome-related studies.
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