Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU533 (Nape-Pld activator) is a NAPE-PLD activator with an EC50 value of 0.30 µM.VU533 enhances NAPE-PLD activity and increases macrophage cytosolic burial.VU533 may be used in diseases associated with cardiometabolism.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 43.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 163.00 | |
25 mg | In stock | $ 328.00 | |
50 mg | In stock | $ 538.00 | |
100 mg | In stock | $ 768.00 | |
500 mg | In stock | $ 1,550.00 |
Description | VU533 (Nape-Pld activator) is a NAPE-PLD activator with an EC50 value of 0.30 µM.VU533 enhances NAPE-PLD activity and increases macrophage cytosolic burial.VU533 may be used in diseases associated with cardiometabolism. |
Targets&IC50 | NAPE-PLD:0.30 μM(EC50) |
In vitro |
VU533 (NAPE-PLD activator) (0.1-30 μM; 24 h) is non-cytotoxic to RAW264.7 and HepG2 cells.[1] VU533 (0.1-30 μM; 24 h) increases NAPE-PLD activity in a concentration-dependent manner in RAW264.7 cells and HepG2 cells.[1] VU533 (10 μM; 6 h) increases efferocytosis of bone marrow-derived macrophages (BMDM) isolated from wild-type mice.[1] |
Synonyms | Nape-Pld activator |
Molecular Weight | 447.55 |
Formula | C21H22FN3O3S2 |
CAS No. | 923417-09-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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VU533 923417-09-8 Metabolism Phospholipase VU 533 Nape-Pld activator VU-533 inhibitor inhibit