iri — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T32192	IRI-426	Ac-Arg-Pro-Asp-Val-Phe-NH2,IRI426
	IRI-426 is a bioactive chemical.
T9073	SRS16-86		Ferroptosis
	SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.		Ferroptosis
T31860	Fosdevirine	GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A	HIV Protease
	Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.		HIV Protease
T28978	Tirilazad mesylate	U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate	Antiviral
	Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c...		Antiviral
T5782	Bevirimat	YK FH312,MPC-4326,PA-457	HIV Protease
	Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation.		HIV Protease
T77423	Lirilumab	ONO-4483,IPH2102	Virus Protease
	Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-depende...		Virus Protease
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T31860L	(Iso)-Fosdevirine	(Iso)-Fosdevirine（Iso-1018450-26-4）,(Iso)-GSK2248761	HIV Protease
	(Iso)-Fosdevirine ( (Iso)-GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological disorders such as late-onset epilepsy.		HIV Protease
T19699	Triciribine phosphate	TCN-P,VD 002,VQD-002	Apoptosis , Akt
	Triciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia.		Apoptosis , Akt
T21142	Bupirimate	Nimrod	Antifungal
	Bupirimate (Nimrod), an active ingredient in plant protection products, is commonly used as a systemic fungicide and finds applications in controlling powdery mildew in roses, apple plantations. It belongs to the family ...		Antifungal
T5S0331	Isoliquiritin	Neoisoliquritin	p53 , Antifungal
	1. Isoliquiritin (Neoisoliquritin) has antitussive effects. 2. Isoliquiritin has antidepressant-like effects. 3. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk betwee...		p53 , Antifungal
T28174	Niridazole	BA32644,BA-32644,Ambilhar,BA 32644
	Niridazole (Ambilhar) is an antiparasitic compound belonging to nitroimidazoles. Niridazole is primarily used to treat schistosomiasis, which kills the parasite by interfering with its metabolism. Niridazole rapidly conc...
T5193	Danirixin	GSK1325756	CXCR
	Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).		CXCR
T3860	Isoliquiritin apioside		MMP , p38 MAPK , NF-κB
	Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...		MMP , p38 MAPK , NF-κB
TN1054	Loureirin C		Others
	Loureirin C can inhibit the activities of thrombin in vitro effectively.		Others
T68081	Girisopam
	Girisopam is a novel selective benzodiazepine analog for the 2,3-benzodiazepine binding site, an atypical psychoanalytic with anxiolytic effects.
T25702	Levovirin	ICN 17261,L-Ribavirin,ICN-17261,ICN17261
	Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin. Levovirin has similar immunomodulatory activity but does not have direct antiviral activity or h...
T5S2205	Sibiricaxanthone B		Others
	Sibiricaxanthone B is an oxygen-containing xanthone isolated from Polygala tenuifolia.		Others
T5S2195	Sibiricose A5		Dehydrogenase
	Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia.		Dehydrogenase
TN1984	Neoisoliquiritin		Others
	Neoisoliquiritin is a natural product from Glycyrrhiza uralensis.		Others