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Search Result

Search Results for " myeloma "

Targets

HDAC

168

Compounds

9

Natural Products

50

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T9745 Elevenostat HDAC
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.
T10981 DCZ0415 Apoptosis , Others , NF-κB
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ...
T8719 SC99 Apoptosis , JAK , STAT
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...
T22277 BMS-P5 PAD
BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.
T3971 CASIN Pirl1-related Compound 2 CDK , STAT , Ras
CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
T9370 DCBP-1 Epigenetic Reader Domain , Ligand for E3 Ligase
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing.
T9918 Daratumumab Others
Daratumumab is a human monoclonal antibody that targets CD38 a cell surface protein that is overexpressed on multiple myeloma MM) cells.
T5484 GSK467 Histone Demethylase , Histone Methyltransferase
GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).
T6796 CB-5083 CB5083,CB 5083 p97
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
T9573 GSK3685032 DNA Methyltransferase
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits c...
T12871 Talmapimod SCIO-469 p38 MAPK
Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 ...
T41290 MST-312 Telomerase Inhibitor IX Telomerase
MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
T2345 PTC-209 PTC209,PTC 209 BMI-1 , Autophagy
PTC-209 is a potent and selective BMI-1 inhibitor.
T6800 CCF642 AC1LYELL Others
CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.
T22277L BMS-P5 free base PAD
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-...
T7779 Nelfinavir AG1341 HIV Protease
Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
T22922 Lenalidomide hemihydrate TNF , Ligand for E3 Ligase , Molecular Glues
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.
T8342 BRD9876 Others , Kinesin , Microtubule Associated
BRD9876 is a selective inhibitor of MM1S growth.
T3661 Citarinostat ACY241,HDAC-IN-2 HDAC
ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...
T1642 Lenalidomide CC-5013 Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
Lenalidomide (CC-5013) is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.
T7791 Iberdomide CC-220 Apoptosis , Ligand for E3 Ligase
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
T1979 AVN-944 VX-944 Dehydrogenase
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T4134 OTS514 hydrochloride OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base)) Apoptosis , TOPK
OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).
T6079 NVP-ADW742 ADW742,ADW,GSK 552602A Apoptosis , IGF-1R
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
T6001 Nelfinavir Mesylate Viracept,Nelfin,AG1343,AG 1343 Mesylate HIV Protease
Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM).
T2241 Alisertib MLN 8237 Apoptosis , Aurora Kinase , Autophagy
Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.
T1776 Plerixafor JM3100,AMD 3100,AMD-3329 Virus Protease , HIV Protease , CXCR
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.
T21503 (E/Z)-Zotiraciclib (E/Z)-TG02,(E/Z)-SB1317 FLT , JAK , CDK
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.
TP1540 Jagged-1 （188-204） Jagged-1 188-204 Gamma-secretase
Jagged-1 （188-204）is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolay...
T6178 PTC-209 hydrobromide PTC-209 HBr BMI-1 , Autophagy
PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).
T4134L OTS514 OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514 Apoptosis , TOPK
OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatmen...
T11141 E64FC26 Others
E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer.
T14918 CDK9-IN-2 Others , CDK
CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively.
T39989L JQKD82 trihydrochloride Histone Demethylase
JQKD82 trihydrochloride, a cell-permeable and selective inhibitor of KDM5, enhances H3K4me3 levels and is utilized in multiple myeloma research.
T26644 Apomine SK&F-99085,APB-231-A2,APB-231-A-2,SR-9223i,SK&F-99085,SR-45023A HMG-CoA Reductase
Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylg...
T76882 Talquetamab JNJ-64407564,JNJ-7564 Dopamine Receptor
Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody for multiple myeloma with antitumor activity that induces T-cell-mediated killing of GPRC5-expressing MM cells through T-cell recruitment and ...
T73450 TH-Z145 Others
TH-Z145 is a potent FPPS inhibitor for the study of myeloma and lung cancer.
T9006 LEM-14 Others
LEM-14 is a potent NSD2-specific inhibitor (IC50:132 μM).LEM-14 may be used in the study of multiple myeloma.
T27582 ICRT-5 iCRT 5,iCRT5 Apoptosis , Wnt/beta-catenin
iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity, blocking Wnt/β-catenin expression and inducing apoptosis. iCRT-5 can be used in the study of multiple myeloma.
T23911 CPS-11 CPS11,CPS 11,N-(Hydroxymethyl)thalidomide Dehydrogenase , NF-κB , Reactive Oxygen Species
CPS-11 (N-(Hydroxymethyl)thalidomide) is a Thalidomide analogue that has significant antitumor activity and exhibits a wider range of activity and highly potent effects on the MM (multiple myeloma) cell line.
TQ0101 MKC3946 IRE1
MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.
T12644L (S)-Thalidomide (S)-(-)-Thalidomide Apoptosis
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu...
T61556 GRK6-IN-2 GRK
GRK6-IN-2 is a potent G protein-coupled receptor kinase 6 (GRK6) inhibitor with potential antitumor activity.GRK6-IN-2 has been studied in multiple myeloma.
T77006 Felzartamab TJ-202,MOR-03087,MOR-202 CD38
Felzartamab(MOR-202) is a human-targeted monoclonal antibody to CD38 for the study of multiple myeloma and advanced antibody-mediated rejection of allogeneic kidney transplants.
T15648 KDM5-C70 Histone Demethylase
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e...
T76927 Bersanlimab BI-505 Integrin
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties and can be used to study relapsed/refractory multiple myeloma.
TP1806L BCMA72-80 acetate(2293841-58-2 free base) Others
BCMA72-80 acetate is a HLA-A2 specific B cell maturation antigen (BCMA) peptide. It is used to study multiple myeloma and tumors, which expresses B cell maturation antigen.
T1795 Carfilzomib PR-171 Apoptosis , Proteasome , Autophagy
Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome. Carfilzomib has antitumor activity and may be used to treat multiple myeloma.
T2709 TAK-901 TAK901 JAK , CDK , Src , Aurora Kinase
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
T77685 6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile PDK
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is a PDK1 inhibitor with anticancer and antiproliferative activity that can be used to study angiosarcoma, adenocarcinoma, multiple myeloma, psoriasis, prostate can...

Compounds

Elevenostat
T9745
Synonym:
Target: HDAC
DCZ0415
T10981
Synonym:
Target: Apoptosis, Others, NF-κB
SC99
T8719
Synonym:
Target: Apoptosis, JAK, STAT
BMS-P5
T22277
Synonym:
Target: PAD
CASIN
T3971
Synonym: Pirl1-related Compound 2
Target: CDK, STAT, Ras
dCBP-1
T9370
Synonym:
Target: Epigenetic Reader Domain, Ligand for E3 Ligase
Daratumumab
T9918
Synonym:
Target: Others
GSK467
T5484
Synonym:
Target: Histone Demethylase, Histone Methyltransferase
CB-5083
T6796
Synonym: CB5083,CB 5083
Target: p97
GSK3685032
T9573
Synonym:
Target: DNA Methyltransferase
Talmapimod
T12871
Synonym: SCIO-469
Target: p38 MAPK
MST-312
T41290
Synonym: Telomerase Inhibitor IX
Target: Telomerase
PTC-209
T2345
Synonym: PTC209,PTC 209
Target: BMI-1, Autophagy
CCF642
T6800
Synonym: AC1LYELL
Target: Others
BMS-P5 free base
T22277L
Synonym:
Target: PAD
Nelfinavir
T7779
Synonym: AG1341
Target: HIV Protease
Lenalidomide hemihydrate
T22922
Synonym:
Target: TNF, Ligand for E3 Ligase, Molecular Glues
BRD9876
T8342
Synonym:
Target: Others, Kinesin, Microtubule Associated
Citarinostat
T3661
Synonym: ACY241,HDAC-IN-2
Target: HDAC
Lenalidomide
T1642
Synonym: CC-5013
Target: Apoptosis, TNF, Ligand for E3 Ligase, Molecular Glues
Iberdomide
T7791
Synonym: CC-220
Target: Apoptosis, Ligand for E3 Ligase
AVN-944
T1979
Synonym: VX-944
Target: Dehydrogenase
OTS514 hydrochloride
T4134
Synonym: OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base))
Target: Apoptosis, TOPK
NVP-ADW742
T6079
Synonym: ADW742,ADW,GSK 552602A
Target: Apoptosis, IGF-1R
Nelfinavir Mesylate
T6001
Synonym: Viracept,Nelfin,AG1343,AG 1343 Mesylate
Target: HIV Protease
Alisertib
T2241
Synonym: MLN 8237
Target: Apoptosis, Aurora Kinase, Autophagy
Plerixafor
T1776
Synonym: JM3100,AMD 3100,AMD-3329
Target: Virus Protease, HIV Protease, CXCR
(E/Z)-Zotiraciclib
T21503
Synonym: (E/Z)-TG02,(E/Z)-SB1317
Target: FLT, JAK, CDK
Jagged-1 （188-204）
TP1540
Synonym: Jagged-1 188-204
Target: Gamma-secretase
PTC-209 hydrobromide
T6178
Synonym: PTC-209 HBr
Target: BMI-1, Autophagy
OTS514
T4134L
Synonym: OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514
Target: Apoptosis, TOPK
E64FC26
T11141
Synonym:
Target: Others
CDK9-IN-2
T14918
Synonym:
Target: Others, CDK
JQKD82 trihydrochloride
T39989L
Synonym:
Target: Histone Demethylase
Apomine
T26644
Synonym: SK&F-99085,APB-231-A2,APB-231-A-2,SR-9223i,SK&F-99085,SR-45023A
Target: HMG-CoA Reductase
Talquetamab
T76882
Synonym: JNJ-64407564,JNJ-7564
Target: Dopamine Receptor
TH-Z145
T73450
Synonym:
Target: Others
LEM-14
T9006
Synonym:
Target: Others
iCRT-5
T27582
Synonym: iCRT 5,iCRT5
Target: Apoptosis, Wnt/beta-catenin
CPS-11
T23911
Synonym: CPS11,CPS 11,N-(Hydroxymethyl)thalidomide
Target: Dehydrogenase, NF-κB, Reactive Oxygen Species
MKC3946
TQ0101
Synonym:
Target: IRE1
(S)-Thalidomide
T12644L
Synonym: (S)-(-)-Thalidomide
Target: Apoptosis
GRK6-IN-2
T61556
Synonym:
Target: GRK
Felzartamab
T77006
Synonym: TJ-202,MOR-03087,MOR-202
Target: CD38
KDM5-C70
T15648
Synonym:
Target: Histone Demethylase
Bersanlimab
T76927
Synonym: BI-505
Target: Integrin
BCMA72-80 acetate(2293841-58-2 free base)
TP1806L
Synonym:
Target: Others
Carfilzomib
T1795
Synonym: PR-171
Target: Apoptosis, Proteasome, Autophagy
TAK-901
T2709
Synonym: TAK901
Target: JAK, CDK, Src, Aurora Kinase
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
T77685
Synonym:
Target: PDK
1 2 3 4
Cat No. Product Name Synonyms Targets
T3002 Piperine 1-Piperoylpiperidine,Bioperine P450 , Endogenous Metabolite , P-gp , Autophagy
Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.
T3398 Icaritin Anhydroicaritin,Cycloicaritin Apoptosis , JAK , STAT , Autophagy
Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...
T71909 Kumbicin C
Kumbicin C inhibits the growth of NS-1 mouse myeloma cells (IC50 = 0.74 μg/ml) and the growth of the Gram-positive bacteria B. subtilis (MIC = 1.6 μg/ml).
T70495 Scytonemin
Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and a...
T35910 Petromurin C
Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vit...
T36337 Burnettramic Acid A aglycone
Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS-1 murine myeloma cells but not neona...
TN3870 Iriflophenone 2-O-Rhamnoside Dimethylmatairesinol Others
Dimethylmatairesinol can reduce the amount of Immunoglobulin E (IgE) secreted by human myeloma U266 cells, it has potential as an anti-allergic agent. Dimethylmatairesinol also exhibits significant cytotoxicity against t...
T72133 Asterriquinol D dimethyl ether
Asterriquinol D dimethyl ether, a fungal metabolite, inhibits mouse myeloma NS-1 cell lines, demonstrating an IC50 value of 28 μg/mL. Additionally, it also acts against Tritrichomonas foetus.
T27174 Dihydrocelastrol DHCE. (-)-Triptohypol C,Triptohypol C
Dihydrocelastrol is synthesized by hydrogenation of celastrol, a treterpene isolated from Chinese medicinal plant Tripterygium regelii. Dihydrocelastrol could inhibit cell proliferation and promote apoptosis through casp...

Natural Products

Piperine
T3002
Synonym: 1-Piperoylpiperidine,Bioperine
Target: P450, Endogenous Metabolite, P-gp, Autophagy
Icaritin
T3398
Synonym: Anhydroicaritin,Cycloicaritin
Target: Apoptosis, JAK, STAT, Autophagy
Kumbicin C
T71909
Synonym:
Target:
Scytonemin
T70495
Synonym:
Target:
Petromurin C
T35910
Synonym:
Target:
Burnettramic Acid A aglycone
T36337
Synonym:
Target:
Iriflophenone 2-O-Rhamnoside
TN3870
Synonym: Dimethylmatairesinol
Target: Others
Asterriquinol D dimethyl ether
T72133
Synonym:
Target:
Dihydrocelastrol
T27174
Synonym: DHCE. (-)-Triptohypol C,Triptohypol C
Target:

Recombinant Proteins

Species：
Human (30)
Mouse (11)
Cynomolgus (2)
Rat (2)
Rhesus (2)
Rabbit (1)
Rhesus macaque (1)
Sheep (1)
Expression System：
HEK293 (39)
E. coli (6)
Human Cells (3)
Baculovirus-Insect Cells (1)
Yeast (1)
Tag：
His (9)
Tag Free (7)
hFc (7)
hFc,AVI (3)
(2)
C-His-Avi (2)
His,FLAG (2)
His,Fc (2)
His,hFc (2)
N-His (2)
Cat No. Product Name Species Expression System
TMPY-04730 LAG-3 Protein, Human, Recombinant (His) Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-05092 LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) Cynomolgus HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04939 LAG-3 Protein, Human, Recombinant Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04493 BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05568 BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-03213 BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01257 UPAR/PLAUR Protein, Mouse, Recombinant (His) Mouse HEK293
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
TMPY-02141 UPAR/PLAUR Protein, Human, Recombinant (His) Human HEK293
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
TMPK-00974 SP17 Protein, Human, Recombinant (His) Human E. coli
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human s...
TMPK-01035 SP17 Protein, Mouse, Recombinant (His) Mouse E. coli
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human s...
TMPK-00358 CD229 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on th...
TMPJ-00331 IFNAR1 Protein, Rhesus macaque, Recombinant (His) Rhesus macaque Human Cells
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-...
TMPK-00357 CD229 Protein, Human, Recombinant (His & Avi) Human HEK293
CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on th...
TMPY-04409 GRK6 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
G protein-coupled receptor kinase 6, also known as G protein-coupled receptor kinase GRK6, GRK6, and GPRK6, is a lipid-anchor protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, and...
TMPK-01193 GPRC5D Protein-VLP, Mouse, Recombinant Mouse HEK293
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP...
TMPK-00528 GPRC5D Protein-VLP, Cynomolgus, Recombinant Cynomolgus HEK293
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GP...
TMPY-02924 RGS1 Protein, Human, Recombinant (His) Human E. coli
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization o...
TMPY-06806 GPRC5D Protein, Human, Recombinant, Fluorescent Human HEK293
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is...
TMPY-06601 GPRC5D Protein, Human, Recombinant, Biotinylated Human HEK293
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is...
TMPY-06719 GPRC5D Protein, Human, Recombinant (His & FLAG) Human HEK293
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is...
TMPY-06718 GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent Human HEK293
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is...
TMPY-06807 GPRC5D Protein, Mouse, Recombinant (Flag) Mouse HEK293
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is...
TMPY-06494 GPRC5D Protein-VLP, Human, Recombinant Human HEK293
Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is...
TMPJ-00291 IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to...
TMPY-05130 LAG-3 Protein, Human, Recombinant, Biotinylated Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04611 LAG-3 Protein, Mouse, Recombinant (hFc) Mouse HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04528 LAG-3 Protein, Human, Recombinant (hFc) Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-03759 LAG-3 Protein, Rat, Recombinant (His) Rat HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-05746 LAG-3 Protein, Mouse, Recombinant Mouse HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-06931 LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04612 LAG-3 Protein, Mouse, Recombinant (His) Mouse HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04731 LAG-3 Protein, Human, Recombinant (mFc) Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPJ-00130 SLAMF2 Protein, Human, Recombinant (hFc & His) Human Human Cells
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, b...
TMPJ-00694 BRD4 Protein, Human, Recombinant (His & Flag) Human E. coli
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remain...
TMPY-02843 GPX7 Protein, Human, Recombinant (hFc) Human HEK293
GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to ...
TMPY-00966 BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05328 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-06757 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05385 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05567 BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02913 BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc) Rat HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05197 BCMA/TNFRSF17 Protein, Human, Recombinant (mFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05595 BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated Mouse HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01211 BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05136 BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01017 UPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ...
TMPY-01710 IkB alpha/NFKBIA Protein, Human, Recombinant (His) Human E. coli
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NF...
TMPH-03208 IL-6 Protein, Rabbit, Recombinant (His) Rabbit Yeast
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
TMPH-03500 IL-6 Protein, Sheep, Recombinant (GST) Sheep E. coli
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
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LAG-3 Protein, Human, Recombinant (His)
TMPY-04730
Species: Human
Expression System: HEK293
LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
TMPY-05092
Species: Cynomolgus
Expression System: HEK293
LAG-3 Protein, Human, Recombinant
TMPY-04939
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)
TMPY-04493
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
TMPY-05568
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)
TMPY-03213
Species: Rhesus
Expression System: HEK293
uPAR/PLAUR Protein, Mouse, Recombinant (His)
TMPY-01257
Species: Mouse
Expression System: HEK293
uPAR/PLAUR Protein, Human, Recombinant (His)
TMPY-02141
Species: Human
Expression System: HEK293
SP17 Protein, Human, Recombinant (His)
TMPK-00974
Species: Human
Expression System: E. coli
SP17 Protein, Mouse, Recombinant (His)
TMPK-01035
Species: Mouse
Expression System: E. coli
CD229 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00358
Species: Human
Expression System: HEK293
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00331
Species: Rhesus macaque
Expression System: Human Cells
CD229 Protein, Human, Recombinant (His & Avi)
TMPK-00357
Species: Human
Expression System: HEK293
GRK6 Protein, Human, Recombinant (His & GST)
TMPY-04409
Species: Human
Expression System: Baculovirus-Insect Cells
GPRC5D Protein-VLP, Mouse, Recombinant
TMPK-01193
Species: Mouse
Expression System: HEK293
GPRC5D Protein-VLP, Cynomolgus, Recombinant
TMPK-00528
Species: Cynomolgus
Expression System: HEK293
RGS1 Protein, Human, Recombinant (His)
TMPY-02924
Species: Human
Expression System: E. coli
GPRC5D Protein, Human, Recombinant, Fluorescent
TMPY-06806
Species: Human
Expression System: HEK293
GPRC5D Protein, Human, Recombinant, Biotinylated
TMPY-06601
Species: Human
Expression System: HEK293
GPRC5D Protein, Human, Recombinant (His & FLAG)
TMPY-06719
Species: Human
Expression System: HEK293
GPRC5D Protein, Human, Recombinant (His & FLAG), Detergent
TMPY-06718
Species: Human
Expression System: HEK293
GPRC5D Protein, Mouse, Recombinant (Flag)
TMPY-06807
Species: Mouse
Expression System: HEK293
GPRC5D Protein-VLP, Human, Recombinant
TMPY-06494
Species: Human
Expression System: HEK293
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00291
Species: Human
Expression System: Human Cells
LAG-3 Protein, Human, Recombinant, Biotinylated
TMPY-05130
Species: Human
Expression System: HEK293
LAG-3 Protein, Mouse, Recombinant (hFc)
TMPY-04611
Species: Mouse
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (hFc)
TMPY-04528
Species: Human
Expression System: HEK293
LAG-3 Protein, Rat, Recombinant (His)
TMPY-03759
Species: Rat
Expression System: HEK293
LAG-3 Protein, Mouse, Recombinant
TMPY-05746
Species: Mouse
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06931
Species: Human
Expression System: HEK293
LAG-3 Protein, Mouse, Recombinant (His)
TMPY-04612
Species: Mouse
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (mFc)
TMPY-04731
Species: Human
Expression System: HEK293
SLAMF2 Protein, Human, Recombinant (hFc & His)
TMPJ-00130
Species: Human
Expression System: Human Cells
BRD4 Protein, Human, Recombinant (His & Flag)
TMPJ-00694
Species: Human
Expression System: E. coli
GPX7 Protein, Human, Recombinant (hFc)
TMPY-02843
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc)
TMPY-00966
Species: Mouse
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
TMPY-05328
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06757
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
TMPY-05385
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
TMPY-05567
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc)
TMPY-02913
Species: Rat
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
TMPY-05197
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
TMPY-05595
Species: Mouse
Expression System: HEK293
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)
TMPY-01211
Species: Mouse
Expression System: HEK293
BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
TMPY-05136
Species: Rhesus
Expression System: HEK293
uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc)
TMPY-01017
Species: Mouse
Expression System: HEK293
IkB alpha/NFKBIA Protein, Human, Recombinant (His)
TMPY-01710
Species: Human
Expression System: E. coli
IL-6 Protein, Rabbit, Recombinant (His)
TMPH-03208
Species: Rabbit
Expression System: Yeast
IL-6 Protein, Sheep, Recombinant (GST)
TMPH-03500
Species: Sheep
Expression System: E. coli
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Cat No. Product Name
L1100 Protease Inhibitor Library

344 compounds
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;

Libraries

Protease Inhibitor Library
L1100
Compounds: 344
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