disodium

Disodium succinate (Sodium succinate) is the sodium salt form of succinate, which is an important metabolite at the cross-road of several metabolic pathways and involved in the formation and elimination of reactive oxygen species.

Stearyl glycyrrhetinate, the stearyl ester of 18-β-glycyrrhetinic acid, has been demonstrated to improve antiviral effects, reduce inflammation and suppress allergies in the pharmaceutical and cosmetic industry.

Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and serves as an energy source for translation and other critical cellular processes.

(1R,2S)-Xeruborbactam disodium ((1R,2S)-QPX7728 disodium) is a boronic acid derivative with antibacterial activity, used in the study of bacterial infections.

QPX7728 disodium (Xeruborbactam disodium) is a cyclic boronate inhibitor of many serine and metal-β-lactamases with antibacterial activity, used in research on bacterial infections.

DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor

ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).

cGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I interferons and other immune mediators by activating interferon gene stimulator (STING). cGAMP disodium is a potent sublingual immune adjuvant that enables better immune function (serum anti-PA neutralization and airway secretions anti-PA SIgA response).

Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively.

EC-17 (disodium salt), a folate receptor alpha (FRα) targeting contrast agent, exhibits fluorescent properties within the visible light spectrum, characterized by peak excitation and emission wavelengths of 470/520 nm, respectively.

SPR720 disodium is an orally active and potent phosphate VXc-486 prodrug,has potent bactericidal activities in vivo.

Levoleucovorin disodium is the sodium salt of the enantiomerically active form of Folinic Acid.

Cinfenoac disodium is a chalcone derivative with anti-inflammatory properties, and it can be utilized in the study of allergic diseases.

Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.

CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.

Disodium nitrilotriacetate is used as a chelating agent, which forms coordination compounds with metal ions such as Fe3+, Cu2+, and Ca2+.

8-Br-7-CH-cADPR disodium (7-Deaza-8-bromo-cADPR) is a potent antagonist of cADPR. It partially inhibits calcium increase induced by sTIR dimerization and significantly reduces axonal degeneration induced by paclitaxel.

PMEG-DP disodium is an effective inhibitor of DNA polymerase (IC50=2.5 μM), exerting strong inhibitory effects particularly on DNA polymerases α and δ. As the active metabolite of GS-9191, it efficiently impedes the growth of cell lines infected with human papillomavirus (HPV). PMEG-DP disodium is useful in research related to HPV-associated diseases.

D-α-Hydroxyglutaric acid-D5 disodium isodium (Disodium (R)-2-hydroxyglutarate-D5) is the deuterated version of D-α-Hydroxyglutaric acid disodium. This compound is a major metabolite that accumulates in the neurometabolic disorder D-2-hydroxyglutaric aciduria. As a weak competitive antagonist of α-ketoglutaric acid (α-KG), D-α-Hydroxyglutaric acid disodium (T6820) inhibits various α-KG-dependent dioxygenases with a Ki of 10.87 mM. It also promotes the production of reactive oxygen species (ROS), binds to and inhibits ATP synthase, and suppresses mTOR signaling.

Tetrahydroxyquinone disodium is a bioactive chemical.

Cholic acid 3-O-glucuronide (OCA-3-glucuronide) disodium acts as an agonist for the farnesoid X receptor (FXR) with an EC50 of 91.5 μM. It holds potential for research in bile acid metabolism and detoxification.

Ganciclovir triphosphate (GCV-TP) disodium is a synthetic analog of 2'-deoxyguanosine known for its ability to inhibit the replication of human cytomegalovirus (CMV). It works by binding to viral DNA polymerase, disrupting viral DNA synthesis, and is effective against CMV strains from humans, monkeys, rodents, and guinea pigs, with an IC50 of 0.01 μM. Additionally, Ganciclovir triphosphate disodium is utilized in gene-directed enzyme prodrug therapy for cancer inhibition.

Glycerophosphoinositol 4-phosphate (GroPIns-4-P) disodium is a metabolite of phospholipase A and an inhibitor of adenylate cyclase. This compound can regulate cAMP-dependent cellular functions and also induces membrane ruffling and stress fiber formation in serum-starved Swiss 3T3 cells by activating small GTPases Rac and Rho, respectively. It is useful for research on cancer cell motility and invasion.

FP-18 disodium is a TLR-4 agonist and acts as a vaccine adjuvant.