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Search Results for " cathepsin "

Targets

122

Compounds

11

Natural Products

55

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6015 Cathepsin Inhibitor 1 Cysteine Protease
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
T37504L Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies...
T60812 Cathepsin X-IN-1 Cysteine Protease
Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].
TQ0116 LY 3000328 Cathepsin S inhibitor Cysteine Protease
LY 3000328 (Cathepsin S inhibitor) is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).
T3420 CA-074 methyl ester Cathepsin B Inhibitor IV,CA-074Me Cysteine Protease
CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects.
T11554 Cathepsin Inhibitor 2 Cysteine Protease
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
T38254 Cathepsin D and E FRET Substrate acetate
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool f...
T37504 Cathepsin D and E FRET Substrate
Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.
T80052 Cathepsin B
Cathepsin B, a cysteine protease, plays a role in various forms of programmed cell death, such as apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death [1].
T62659 Cathepsin C-IN-4
Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).
T64159 Cathepsin K inhibitor 2
Cathepsin K inhibitor 2 is a potent inhibitor of cathepsin K. Cathepsin K (Cat K) is a cysteine protease expressed under the control of the CTSK gene, which is closely related to osteoporosis and hydrolyses collagen. cat...
T80333 Cathepsin G(1-5)
Cathepsin G(1-5), an antimicrobial peptide identified within the clostripain-digested cathepsin G mixture [1], exhibits bactericidal properties.
T62494 Cathepsin C-IN-5
Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC 50 s of 59.9 nM, 4.26 µM, >5 µM, >5 µM, >5 µM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 ...
T63854 Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).
T72296 Cathepsin K inhibitor 3
Cathepsin K inhibitor 3 is a highly selective cathepsin K inhibitor with an IC 50 value of 0.5 nM. Cathepsin K inhibitor 3 has a favorable pharmacokinetic profile and may be used in osteoarthritis (OA) disease studies .
T79496 Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase activation. This compound demonstrates potential efficacy in tr...
T72569 Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 is a dual inhibitor of Cathepsin L and Cathepsin S with IC 50 s of 4.10 μM and 1.79 μM, respectively. Cathepsin L/S-IN-1 shows a significant antimetastatic and invasive effects on pancreatic cancer BxP...
T38469 (Rac)-Z-Phe-Phe-FMK Cathepsin L-IN-2 Beta Amyloid , Cysteine Protease
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .
T6432 Calpeptin Apoptosis , Cysteine Protease , Proteasome
Calpeptin is a potent, cell-permeable calpain inhibitor.
T27989 MDK0734 Cathepsin B Inhinitor-42
MDK0734 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.
T28003 MDK7677 Cathepsin B Inhinitor-17,MDK 7677
MDK7677 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.
T13288 VBY-825 Cysteine Protease
VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
T27730 KGP94 KGP-94,KGP 94 Cysteine Protease
KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).
T16777 ROC-325 Apoptosis , Autophagy
ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.
T0789 PMSF Phenylmethylsulfonyl fluoride,Benzylsulfonyl fluoride Serine Protease , Cysteine Protease
Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.
T12909 SID 26681509 Cysteine Protease , Parasite
SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).
T6035 Odanacatib MK-0822 Cysteine Protease
Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
T21616 L-006235 L 006235 Cysteine Protease
L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.
T6738 Z-FA-FMK SARS-CoV , Cysteine Protease
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
T7451 2-Cyanopyrimidine 2-cyano-Pyrimidine Cysteine Protease
2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)
T1850 Balicatib AAE581 Cysteine Protease
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
T6040 Aloxistatin E64d,Loxistatin,E64c ethyl ester SARS-CoV , Cysteine Protease
Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with...
TP1015 NFAT Inhibitor VIVIT peptide Others
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.
T6037 E-64 Proteinase inhibitor E 64,E 64,E64 Cysteine Protease , Antibacterial , Autophagy
E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.
T1885 Siramesine hydrochloride Lu 28-179 hydrochloride Ferroptosis , Sigma receptor , lysosomal autophagy
Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit a potent anticancer activity in vivo.
T6573 E 64c NSC 694279,EP 475,Loxistatin Acid SARS-CoV , Cysteine Protease
E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.
T10924 Cysteine protease inhibitor-2 Cysteine Protease
Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.
T3088 N-Ethylmaleimide 1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM Cysteine Protease , DUB
N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies.
T4620 Siramesine Lu 28-179 Sigma receptor
Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.lysosome-destabilizing agent siram...
T12051 MIV-247 Cysteine Protease
MIV-247 is a selective and potent inhibitor of cathepsin S (Kis 2.1, 4.2, and 7.5 nM for human, mouse, and wild monkey cathepsin S, respectively), which attenuates mechanical anomalies in preclinical models of neuropathi...
T16089 MK-0674 Cysteine Protease
MK-0674 is an orally available, selective and potent cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S. It can be used in metabolism-related diseases.
T41308L Gly-Phe β-naphthylamide acetate Gly-Phe β-naphthylamide acetate(21438-66-4 Free base) Others
Gly-Phe β-naphthylamide acetate is the substrate of Cathepsin C and can be used for research on the function of cathepsin C, intralysosomal hydrolysis and lysosomal membrane permeability.
T21509 CA 074 Cysteine Protease
CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates retinopathy and optic neuritis in experimental autoimmune encephalom...
T19347 H-Arg-4MβNA H-Arg-4MbNA Others
H-Arg-4MβNA (H-Arg-4MbNA) is a peptide that serves as a substrate for cathepsin H. The enzyme activity is often detected in gel electrophoresis.
T12188 NB-360 BACE
NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cat...
T8677 3,4 Dichloroisocoumarin Others , Serine Protease , Cysteine Protease
3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor
T5149 MC-Val-Cit-PAB Others , AChR
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
TP2056L Acetyl-Calpastatin (184-210)(human) acetate Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base ) Cysteine Protease
Acetyl-Calpastatin (184-210)(human) acetate is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively.
T18540 Phe-Lys(Trt)-PAB Others
Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
T2639 LY2811376 Beta Amyloid , Beta-Secretase , BACE
LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition...

Compounds

Cathepsin Inhibitor 1
T6015
Synonym:
Target: Cysteine Protease
Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
T37504L
Synonym: Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Target:
Cathepsin X-IN-1
T60812
Synonym:
Target: Cysteine Protease
LY 3000328
TQ0116
Synonym: Cathepsin S inhibitor
Target: Cysteine Protease
CA-074 methyl ester
T3420
Synonym: Cathepsin B Inhibitor IV,CA-074Me
Target: Cysteine Protease
Cathepsin Inhibitor 2
T11554
Synonym:
Target: Cysteine Protease
Cathepsin D and E FRET Substrate acetate
T38254
Synonym:
Target:
Cathepsin D and E FRET Substrate
T37504
Synonym:
Target:
Cathepsin B
T80052
Synonym:
Target:
Cathepsin C-IN-4
T62659
Synonym:
Target:
Cathepsin K inhibitor 2
T64159
Synonym:
Target:
Cathepsin G(1-5)
T80333
Synonym:
Target:
Cathepsin C-IN-5
T62494
Synonym:
Target:
Cathepsin C-IN-3
T63854
Synonym:
Target:
Cathepsin K inhibitor 3
T72296
Synonym:
Target:
Cathepsin C-IN-6
T79496
Synonym:
Target:
Cathepsin L/S-IN-1
T72569
Synonym:
Target:
(Rac)-Z-Phe-Phe-FMK
T38469
Synonym: Cathepsin L-IN-2
Target: Beta Amyloid, Cysteine Protease
Calpeptin
T6432
Synonym:
Target: Apoptosis, Cysteine Protease, Proteasome
MDK0734
T27989
Synonym: Cathepsin B Inhinitor-42
Target:
MDK7677
T28003
Synonym: Cathepsin B Inhinitor-17,MDK 7677
Target:
VBY-825
T13288
Synonym:
Target: Cysteine Protease
KGP94
T27730
Synonym: KGP-94,KGP 94
Target: Cysteine Protease
ROC-325
T16777
Synonym:
Target: Apoptosis, Autophagy
PMSF
T0789
Synonym: Phenylmethylsulfonyl fluoride,Benzylsulfonyl fluoride
Target: Serine Protease, Cysteine Protease
SID 26681509
T12909
Synonym:
Target: Cysteine Protease, Parasite
Odanacatib
T6035
Synonym: MK-0822
Target: Cysteine Protease
L-006235
T21616
Synonym: L 006235
Target: Cysteine Protease
Z-FA-FMK
T6738
Synonym:
Target: SARS-CoV, Cysteine Protease
2-Cyanopyrimidine
T7451
Synonym: 2-cyano-Pyrimidine
Target: Cysteine Protease
Balicatib
T1850
Synonym: AAE581
Target: Cysteine Protease
Aloxistatin
T6040
Synonym: E64d,Loxistatin,E64c ethyl ester
Target: SARS-CoV, Cysteine Protease
NFAT Inhibitor
TP1015
Synonym: VIVIT peptide
Target: Others
E-64
T6037
Synonym: Proteinase inhibitor E 64,E 64,E64
Target: Cysteine Protease, Antibacterial, Autophagy
Siramesine hydrochloride
T1885
Synonym: Lu 28-179 hydrochloride
Target: Ferroptosis, Sigma receptor, lysosomal autophagy
E 64c
T6573
Synonym: NSC 694279,EP 475,Loxistatin Acid
Target: SARS-CoV, Cysteine Protease
Cysteine protease inhibitor-2
T10924
Synonym:
Target: Cysteine Protease
N-Ethylmaleimide
T3088
Synonym: 1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM
Target: Cysteine Protease, DUB
Siramesine
T4620
Synonym: Lu 28-179
Target: Sigma receptor
MIV-247
T12051
Synonym:
Target: Cysteine Protease
MK-0674
T16089
Synonym:
Target: Cysteine Protease
Gly-Phe β-naphthylamide acetate
T41308L
Synonym: Gly-Phe β-naphthylamide acetate(21438-66-4 Free base)
Target: Others
CA 074
T21509
Synonym:
Target: Cysteine Protease
H-Arg-4MβNA
T19347
Synonym: H-Arg-4MbNA
Target: Others
NB-360
T12188
Synonym:
Target: BACE
3,4 Dichloroisocoumarin
T8677
Synonym:
Target: Others, Serine Protease, Cysteine Protease
MC-Val-Cit-PAB
T5149
Synonym:
Target: Others, AChR
Acetyl-Calpastatin (184-210)(human) acetate
TP2056L
Synonym: Acetyl-Calpastatin (184-210) (human) acetate(123714-50-1 Free base )
Target: Cysteine Protease
Phe-Lys(Trt)-PAB
T18540
Synonym:
Target: Others
LY2811376
T2639
Synonym:
Target: Beta Amyloid, Beta-Secretase, BACE
1 2 3
Cat No. Product Name Synonyms Targets
T19503 Papain Others , Cysteine Protease
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries.
TJS2216 Aurantiamide acetate Asperglaucide Cysteine Protease
Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta...
T6564 Leupeptin Hemisulfate Serine Protease , Cysteine Protease
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
TN1249 3-Epiursolic acid Cysteine Protease , Immunology/Inflammation related
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered p...
T8709 Nandrolone phenylpropionate Nandrolone phenpropionate Androgen Receptor
Nandrolone phenylpropionate (Nandrolone phenpropionate) is an androgen receptor agonist. It mainly used to treat women with breast cancer and osteoporosis
T5544 2-Furoic acid Furan-2-carboxylic acid Anti-infection , ATP Citrate Lyase , Endogenous Metabolite , Acyltransferase
2-Furoic acid (Furan-2-carboxylic acid), an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosi...
T3417 Amentoflavone Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T19392 L-Homocysteine Others
L-Homocysteine, an L-configured homocysteine metabolite, induces the upregulation of cathepsin V, which mediates vascular endothelial inflammation in hyperhomocysteinaemia.
T15702 Lactacystin Proteasome
Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome inhibitor (IC50: 4.8 μM for 20S proteasome). Lactacystin inhibits cell growth and induces neurite outgrowth and a...
T72898 Gallinamide A
Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.
TN2691 2',3'-Dehydrosalannol BCL , Akt , Caspase
2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits cathepsin-mediated pro-survival signaling which resulted in g...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00731 Cathepsin B Protein, Human, Recombinant (His) Human HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-00735 Cathepsin S Protein, Human, Recombinant (His) Human HEK293
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS...
TMPY-02751 Cathepsin S Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS...
TMPY-02450 Cathepsin D Protein, Human, Recombinant (His) Human HEK293
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly...
TMPY-00439 Cathepsin E Protein, Rat, Recombinant (His) Rat HEK293
Cathepsin E Protein (CTSE Protein) is a member of the peptidase C1 family that is a gastric aspartic protease that functions as a disulfide-linked homodimer. Cathepsin E Protein (CTSE Protein) is predominantly present in...
TMPY-02144 Cathepsin B Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-04503 Cathepsin B Protein, Rat, Recombinant (His) Rat HEK293
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-02699 Cathepsin Z Protein, Human, Recombinant (His) Human HEK293
Cathepsin Z (CTSZ), also known as Cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from ot...
TMPY-00362 Cathepsin S Protein, Rat, Recombinant (His) Rat HEK293
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS...
TMPY-04081 Cathepsin H Protein, Mouse, Recombinant (His) Mouse HEK293
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis.
TMPY-00733 Cathepsin D Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin D (CTSD), a well known lysosomal aspartyl protease and belongs to the peptidase C1 family, which is a normal and major component of lysosomes, and is found in almost all cells and tissues of mammals. Its mostly...
TMPY-01699 Cathepsin E Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin E Protein (CTSE Protein) is a member of the peptidase C1 family that is a gastric aspartic protease that functions as a disulfide-linked homodimer. Cathepsin E Protein (CTSE Protein) is predominantly present in...
TMPY-01450 Cathepsin A Protein, Mouse, Recombinant (His) Mouse HEK293
Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL an...
TMPY-02171 Cathepsin L Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin L is a lysosomal cysteine protease that plays a major role in intracellular protein catabolism, and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural ...
TMPY-01249 Cathepsin V Protein, Human, Recombinant (His) Human HEK293
Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
TMPY-00734 Cathepsin L Protein, Human, Recombinant (His) Human HEK293
Cathepsin L is a lysosomal cysteine protease that plays a major role in intracellular protein catabolism, and is potent in degrading collagen, laminin, elastin, as well as alpha-1 protease inhibitor and other structural ...
TMPY-00736 Cathepsin Z Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin Z (CTSZ), also known as Cathepsin X or CATX, belongs to the C1 family of lysosomal cysteine proteases. Its gene structure and activity properties show several unique features that distinguish it clearly from ot...
TMPY-00730 Cathepsin A Protein, Human, Recombinant (His) Human HEK293
Lysosomal carboxypeptidase, cathepsin A (protective protein, CathA), is a component of the lysosomal multienzyme complex along with beta-galactosidase (GAL) and sialidase Neu1, where it activates Neu1 and protects GAL an...
TMPY-06479 Cathepsin H Protein, Human, Recombinant (His) Human HEK293
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis.
TMPY-00732 Cathepsin C Protein, Human, Recombinant (His) Human HEK293
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also kno...
TMPJ-00845 CTSE Protein, Human, Recombinant (His) Human Human Cells
Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is loca...
TMPJ-00497 CTSB Protein, Human, Recombinant (His) Human Human Cells
Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, bot...
TMPH-03262 Cathepsin K Protein, Rat, Recombinant (His) Rat E. coli
Can constrain negative DNA supercoils. May be involved in maintaining the integrity of the genome at high temperature. Stimulates the Holliday junction cleavage activity of Hjc.
TMPH-01059 Cathepsin B Protein, Human, Recombinant (GST) Human E. coli
TMPH-02565 Cathepsin K Protein, Mouse, Recombinant (His) Mouse E. coli
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
TMPH-00134 AcMNPV Viral cathepsin Protein (His & SUMO) AcMNPV E. coli
TMPH-01060 Cathepsin F Protein, Human, Recombinant (His) Human E. coli
TMPH-01061 Cathepsin K Protein, Human, Recombinant (His) Human E. coli
TMPH-00060 ApNPV Viral cathepsin Protein (His & Myc) ApNPV E. coli
TMPH-01063 Cathepsin O Protein, Human, Recombinant (His & Myc) Human HEK293
TMPH-02566 Cathepsin W Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
TMPH-03261 Cathepsin D Protein, Rat, Recombinant (His & Myc) Rat E. coli
Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular...
TMPH-03263 Cathepsin Z Protein, Rat, Recombinant (His & SUMO) Rat E. coli
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.
TMPH-02628 Cathepsin C Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classic...
TMPH-01062 Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
TMPJ-00508 CTSL Protein, Human, Recombinant (His) Human Human Cells
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tu...
TMPH-00437 Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO) Chinese hamster E. coli
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
TMPY-00672 Azurocidin/CAP37 Protein, Human, Recombinant (His) Human HEK293
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil...
TMPJ-01204 TPSAB1 Protein, Human, Recombinant (His) Human Human Cells
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPJ-00708 CST7 Protein, Mouse, Recombinant (His) Mouse Human Cells
Mouse Cystatin F belongs to cystatin superfamily, which encompasses proteins that contain multiple cystatin-like sequences. It has been shown that Cystatin F is selectively expressed by hematopoietic cells and may be a b...
TMPY-01644 Cystatin S Protein, Human, Recombinant (His) Human HEK293
Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual sali...
TMPJ-01287 Sialidase-1 Protein, Human, Recombinant (His) Human Human Cells
Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cl...
TMPJ-00869 GLB1 Protein, Human, Recombinant (His) Human Human Cells
β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase ...
TMPY-00729 Cystatin D Protein, Human, Recombinant (His) Human HEK293
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef...
TMPY-00770 Cystatin F/CST7 Protein, Human, Recombinant Human HEK293
The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
TMPY-00768 CST6 Protein, Human, Recombinant (His) Human HEK293
Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing ...
TMPY-02717 GPR37 Protein, Human, Recombinant (His) Human HEK293
GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside ...
TMPY-01303 Serpin A3 Protein, Human, Recombinant (His) Human HEK293
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPY-01368 Cystatin F/CST7 Protein, Human, Recombinant (His) Human HEK293
The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
TMPY-02856 Cystatin F/CST7 Protein, Mouse, Recombinant (hFc) Mouse HEK293
The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
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Cathepsin B Protein, Human, Recombinant (His)
TMPY-00731
Species: Human
Expression System: HEK293
Cathepsin S Protein, Human, Recombinant (His)
TMPY-00735
Species: Human
Expression System: HEK293
Cathepsin S Protein, Mouse, Recombinant (His)
TMPY-02751
Species: Mouse
Expression System: HEK293
Cathepsin D Protein, Human, Recombinant (His)
TMPY-02450
Species: Human
Expression System: HEK293
Cathepsin E Protein, Rat, Recombinant (His)
TMPY-00439
Species: Rat
Expression System: HEK293
Cathepsin B Protein, Mouse, Recombinant (His)
TMPY-02144
Species: Mouse
Expression System: HEK293
Cathepsin B Protein, Rat, Recombinant (His)
TMPY-04503
Species: Rat
Expression System: HEK293
Cathepsin Z Protein, Human, Recombinant (His)
TMPY-02699
Species: Human
Expression System: HEK293
Cathepsin S Protein, Rat, Recombinant (His)
TMPY-00362
Species: Rat
Expression System: HEK293
Cathepsin H Protein, Mouse, Recombinant (His)
TMPY-04081
Species: Mouse
Expression System: HEK293
Cathepsin D Protein, Mouse, Recombinant (His)
TMPY-00733
Species: Mouse
Expression System: HEK293
Cathepsin E Protein, Mouse, Recombinant (His)
TMPY-01699
Species: Mouse
Expression System: HEK293
Cathepsin A Protein, Mouse, Recombinant (His)
TMPY-01450
Species: Mouse
Expression System: HEK293
Cathepsin L Protein, Mouse, Recombinant (His)
TMPY-02171
Species: Mouse
Expression System: HEK293
Cathepsin V Protein, Human, Recombinant (His)
TMPY-01249
Species: Human
Expression System: HEK293
Cathepsin L Protein, Human, Recombinant (His)
TMPY-00734
Species: Human
Expression System: HEK293
Cathepsin Z Protein, Mouse, Recombinant (His)
TMPY-00736
Species: Mouse
Expression System: HEK293
Cathepsin A Protein, Human, Recombinant (His)
TMPY-00730
Species: Human
Expression System: HEK293
Cathepsin H Protein, Human, Recombinant (His)
TMPY-06479
Species: Human
Expression System: HEK293
Cathepsin C Protein, Human, Recombinant (His)
TMPY-00732
Species: Human
Expression System: HEK293
CTSE Protein, Human, Recombinant (His)
TMPJ-00845
Species: Human
Expression System: Human Cells
CTSB Protein, Human, Recombinant (His)
TMPJ-00497
Species: Human
Expression System: Human Cells
Cathepsin K Protein, Rat, Recombinant (His)
TMPH-03262
Species: Rat
Expression System: E. coli
Cathepsin B Protein, Human, Recombinant (GST)
TMPH-01059
Species: Human
Expression System: E. coli
Cathepsin K Protein, Mouse, Recombinant (His)
TMPH-02565
Species: Mouse
Expression System: E. coli
AcMNPV Viral cathepsin Protein (His & SUMO)
TMPH-00134
Species: AcMNPV
Expression System: E. coli
Cathepsin F Protein, Human, Recombinant (His)
TMPH-01060
Species: Human
Expression System: E. coli
Cathepsin K Protein, Human, Recombinant (His)
TMPH-01061
Species: Human
Expression System: E. coli
ApNPV Viral cathepsin Protein (His & Myc)
TMPH-00060
Species: ApNPV
Expression System: E. coli
Cathepsin O Protein, Human, Recombinant (His & Myc)
TMPH-01063
Species: Human
Expression System: HEK293
Cathepsin W Protein, Mouse, Recombinant (His & Myc)
TMPH-02566
Species: Mouse
Expression System: E. coli
Cathepsin D Protein, Rat, Recombinant (His & Myc)
TMPH-03261
Species: Rat
Expression System: E. coli
Cathepsin Z Protein, Rat, Recombinant (His & SUMO)
TMPH-03263
Species: Rat
Expression System: E. coli
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
TMPH-02628
Species: Mouse
Expression System: E. coli
Cathepsin O Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-01062
Species: Human
Expression System: E. coli
CTSL Protein, Human, Recombinant (His)
TMPJ-00508
Species: Human
Expression System: Human Cells
Cathepsin D Protein, Cricetulus griseus, Recombinant (His & SUMO)
TMPH-00437
Species: Chinese hamster
Expression System: E. coli
Azurocidin/CAP37 Protein, Human, Recombinant (His)
TMPY-00672
Species: Human
Expression System: HEK293
TPSAB1 Protein, Human, Recombinant (His)
TMPJ-01204
Species: Human
Expression System: Human Cells
CST7 Protein, Mouse, Recombinant (His)
TMPJ-00708
Species: Mouse
Expression System: Human Cells
Cystatin S Protein, Human, Recombinant (His)
TMPY-01644
Species: Human
Expression System: HEK293
Sialidase-1 Protein, Human, Recombinant (His)
TMPJ-01287
Species: Human
Expression System: Human Cells
GLB1 Protein, Human, Recombinant (His)
TMPJ-00869
Species: Human
Expression System: Human Cells
Cystatin D Protein, Human, Recombinant (His)
TMPY-00729
Species: Human
Expression System: HEK293
Cystatin F/CST7 Protein, Human, Recombinant
TMPY-00770
Species: Human
Expression System: HEK293
CST6 Protein, Human, Recombinant (His)
TMPY-00768
Species: Human
Expression System: HEK293
GPR37 Protein, Human, Recombinant (His)
TMPY-02717
Species: Human
Expression System: HEK293
Serpin A3 Protein, Human, Recombinant (His)
TMPY-01303
Species: Human
Expression System: HEK293
Cystatin F/CST7 Protein, Human, Recombinant (His)
TMPY-01368
Species: Human
Expression System: HEK293
Cystatin F/CST7 Protein, Mouse, Recombinant (hFc)
TMPY-02856
Species: Mouse
Expression System: HEK293
TargetMol