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Search Results for " antihypertensive "

Targets

203

Compounds

30

Natural Products

1

Libraries

Cat No. Product Name Synonyms Targets
T80661 Antihypertensive sulfonanilide XVII Others
Antihypertensive sulfonanilide XVII is an orally available antihypertensive sulfonanilide small molecule compound for the study of hypertension.
T79267 Antihypertensive agent 3
Antihypertensive agent 3 (compound 4a), an angiotensin II receptor 1 antagonist, demonstrates antihypertensive activity in spontaneously hypertensive rats (SHRs) [1].
T79266 Antihypertensive agent 2
Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or greater potency than Losartan [1].
T5471 GUANABENZ Adrenergic Receptor
GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.
T21640 Talinolol Adrenergic Receptor
(±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.
T2519 Lercanidipine Masnidipine Calcium Channel
Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.
T0300 Pargyline Pargylamine,Paragyline MAO , Monoamine Oxidase
Pargyline (Pargylamine) is a monoamine oxidase inhibitor with antihypertensive properties.
T0114 Trichlormethiazide Naqua,Metahydrin,Trichlormetazid ATPase , Carbonic Anhydrase
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and ...
T6641 Rilmenidine Phosphate Apoptosis , Adrenergic Receptor , Autophagy , Imidazoline Receptor
Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
T21957 Guanabenz hydrochloride NE56490 Adrenergic Receptor
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.
T2531 Eprosartan Mesylate SKF-108566J RAAS
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
T6086 Clopamide Brinaldix,Adurix,Aquex Sodium Channel
Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
T7656 Apelin-13
Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T0388 Cilnidipine FRC-8653 Calcium Channel
Cilnidipine (FRC-8653)(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.
T1578 Pargyline hydrochloride Pargylamine hydrochloride MAO , Monoamine Oxidase
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T19654 Guanoclor VATENSOL Others
Guanoclor (VATENSOL) (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.
T1449 Hydrochlorothiazide HCTZ Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.
T7808 Alacepril Cetapril,DU-1219 RAAS
Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive
T2621 Rostafuroxin PST 2238 ATPase , RSV
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.
T0088 Urapidil hydrochloride Urapidil HCl 5-HT Receptor , Adrenergic Receptor
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.
T22830 GYY4137 GYY 4137 morpholine salt Others
GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity.
T1613 Hydralazine hydrochloride Hydralazine HCl,Apresoline MAO , HIF/HIF Prolyl-Hydroxylase
Hydralazine hydrochloride (Apresoline) is the hydrochloride salt of hydralazine, a phthalazine derivative with antihypertensive and potential antineoplastic activities. Hydralazine alters intracellular calcium release an...
T4574 Sacubitril AHU 377,AHU377,AHU-377 Neprilysin
Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696.
T1461 Candesartan CV 11974 RAAS
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T0119 Nitrendipine BAY-E-5009,Bayotensin Calcium Channel , Autophagy
Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtr...
T6874 Lercanidipine hydrochloride Corifeo,Carmen,Cardiovasc Calcium Channel
Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.
T8315 1-Cyclohexyl-3-dodecyl urea CDU,N-Cyclohexyl-N-dodecyl urea,NCND Epoxide Hydrolase
1-Cyclohexyl-3-dodecyl urea (NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor.
T12478L Pinacidil S 1230,P 1134,S-1230,P-1134,P1134 Potassium Channel
Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.
T10511 Anti-hypertensive sulfonanilide 1 Others
Anti-hypertensive sulfonanilide 1 is an antihypertensive compound.
T3518 GSK269962A GSK269962B,GSK 269962,GSK269962A HCl ROCK , S6 Kinase
GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
T1462 Captopril SQ 14225,SQ-14534,SA333 RAAS
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.
T6542 Imidapril hydrochloride Novaloc,Imidapril HCl,Tanapril,TA-6366 RAAS
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
T0342 Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate) VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T23044 N,N'-Dicyclohexylurea DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582 Epoxide Hydrolase
N,N'-Dicyclohexylurea (AURORA KA-3582) is a soluble epoxide hydrolase (sEH) inhibitor.
T6595 Moexipril hydrochloride Moexipril HCl,RS-10085,SPM 925,CI-925 Apoptosis , RAAS
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
T11109 DU717 DU-717 Others
DU717 is an antihypertensive agent.
T25828 Monatepil maleate AJ2615,AJ 2615,AJ-2615
Monatepil maleate is an Antihypertensive agent. It is a calcium antagonist with alpha(1)-adrenergic receptor blocking activity
T3270 Dihydralazine sulfate 1,4-Dihydrazinophthalazine sulfate,Hydralazine sulfate,Nepresol,Depressan,Dihydralazine sulphate Others
Dihydralazine sulfate (Nepresol) is an antihypertensive agent.
T5964 Olmesartan CS 088,RNH 6270 RAAS
Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist. Olmesartan is the active form of the antihypertensive drug olmesartan medoxomil,and has antihypertensive activity.
T10683 Carmoxirole hydrochloride EMD 45609 hydrochloride Dopamine Receptor
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.
T17266 Xipamide Diurexan,Aquaphor Others
Xipamide (Diurexan) is a sulfonamide-based diuretic with antihypertensive properties. Xipamide selectively inhibits anion exchanger.
T7686 Ramiprilat RAAS
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T15553 Iganidipine NKY 722 Calcium Channel
Iganidipine(NKY 722) is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.
T12478 Pinacidil monohydrate Potassium Channel
Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.
T26923 Bunazosin Hydrochloride E 1015,E643,E-1015,E-643,E 643 Adrenergic Receptor
Bunazosin Hydrochloride (E 1015) is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.
T26939 Cadralazine ISF 2469,ISF-2469,ISF2469 Others
Cadralazine (ISF 2469) is a peripheral arteriolar vasodilator and can be used in studies about acting as an antihypertensive drug.
T1007 Nanofin Lupetidine,Lupetidin,2,6-Lupetidine,2,6-Dimethylpiperidine,Naniopinum AChR
Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.
T1605 Enalapril MK-421 RAAS , MRP
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1520 Aliskiren hemifumarate CGP 60536,SPP 100,CGP60536B RAAS , Autophagy
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity.
T6635 EMD638683 SGK
EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).

Compounds

Antihypertensive sulfonanilide XVII
T80661
Synonym:
Target: Others
Antihypertensive agent 3
T79267
Synonym:
Target:
Antihypertensive agent 2
T79266
Synonym:
Target:
GUANABENZ
T5471
Synonym:
Target: Adrenergic Receptor
Talinolol
T21640
Synonym:
Target: Adrenergic Receptor
Lercanidipine
T2519
Synonym: Masnidipine
Target: Calcium Channel
Pargyline
T0300
Synonym: Pargylamine,Paragyline
Target: MAO, Monoamine Oxidase
Trichlormethiazide
T0114
Synonym: Naqua,Metahydrin,Trichlormetazid
Target: ATPase, Carbonic Anhydrase
Rilmenidine Phosphate
T6641
Synonym:
Target: Apoptosis, Adrenergic Receptor, Autophagy, Imidazoline Receptor
Guanabenz hydrochloride
T21957
Synonym: NE56490
Target: Adrenergic Receptor
Eprosartan Mesylate
T2531
Synonym: SKF-108566J
Target: RAAS
Clopamide
T6086
Synonym: Brinaldix,Adurix,Aquex
Target: Sodium Channel
Apelin-13
T7656
Synonym:
Target:
Cilnidipine
T0388
Synonym: FRC-8653
Target: Calcium Channel
Pargyline hydrochloride
T1578
Synonym: Pargylamine hydrochloride
Target: MAO, Monoamine Oxidase
Guanoclor
T19654
Synonym: VATENSOL
Target: Others
Hydrochlorothiazide
T1449
Synonym: HCTZ
Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad
Alacepril
T7808
Synonym: Cetapril,DU-1219
Target: RAAS
Rostafuroxin
T2621
Synonym: PST 2238
Target: ATPase, RSV
Urapidil hydrochloride
T0088
Synonym: Urapidil HCl
Target: 5-HT Receptor, Adrenergic Receptor
GYY4137
T22830
Synonym: GYY 4137 morpholine salt
Target: Others
Hydralazine hydrochloride
T1613
Synonym: Hydralazine HCl,Apresoline
Target: MAO, HIF/HIF Prolyl-Hydroxylase
Sacubitril
T4574
Synonym: AHU 377,AHU377,AHU-377
Target: Neprilysin
Candesartan
T1461
Synonym: CV 11974
Target: RAAS
Nitrendipine
T0119
Synonym: BAY-E-5009,Bayotensin
Target: Calcium Channel, Autophagy
Lercanidipine hydrochloride
T6874
Synonym: Corifeo,Carmen,Cardiovasc
Target: Calcium Channel
1-Cyclohexyl-3-dodecyl urea
T8315
Synonym: CDU,N-Cyclohexyl-N-dodecyl urea,NCND
Target: Epoxide Hydrolase
Pinacidil
T12478L
Synonym: S 1230,P 1134,S-1230,P-1134,P1134
Target: Potassium Channel
Anti-hypertensive sulfonanilide 1
T10511
Synonym:
Target: Others
GSK269962A
T3518
Synonym: GSK269962B,GSK 269962,GSK269962A HCl
Target: ROCK, S6 Kinase
Captopril
T1462
Synonym: SQ 14225,SQ-14534,SA333
Target: RAAS
Imidapril hydrochloride
T6542
Synonym: Novaloc,Imidapril HCl,Tanapril,TA-6366
Target: RAAS
Carvedilol phosphate hemihydrate
T0342
Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate)
Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy
N,N'-Dicyclohexylurea
T23044
Synonym: DCU,1,3-Dicyclohexylurea,NSC 17013,Dicyclohexylurea,Dicyclohexylcarbodiamide,AURORA KA-3582
Target: Epoxide Hydrolase
Moexipril hydrochloride
T6595
Synonym: Moexipril HCl,RS-10085,SPM 925,CI-925
Target: Apoptosis, RAAS
DU717
T11109
Synonym: DU-717
Target: Others
Monatepil maleate
T25828
Synonym: AJ2615,AJ 2615,AJ-2615
Target:
Dihydralazine sulfate
T3270
Synonym: 1,4-Dihydrazinophthalazine sulfate,Hydralazine sulfate,Nepresol,Depressan,Dihydralazine sulphate
Target: Others
Olmesartan
T5964
Synonym: CS 088,RNH 6270
Target: RAAS
Carmoxirole hydrochloride
T10683
Synonym: EMD 45609 hydrochloride
Target: Dopamine Receptor
Xipamide
T17266
Synonym: Diurexan,Aquaphor
Target: Others
Ramiprilat
T7686
Synonym:
Target: RAAS
Iganidipine
T15553
Synonym: NKY 722
Target: Calcium Channel
Pinacidil monohydrate
T12478
Synonym:
Target: Potassium Channel
Bunazosin Hydrochloride
T26923
Synonym: E 1015,E643,E-1015,E-643,E 643
Target: Adrenergic Receptor
Cadralazine
T26939
Synonym: ISF 2469,ISF-2469,ISF2469
Target: Others
Nanofin
T1007
Synonym: Lupetidine,Lupetidin,2,6-Lupetidine,2,6-Dimethylpiperidine,Naniopinum
Target: AChR
Enalapril
T1605
Synonym: MK-421
Target: RAAS, MRP
Aliskiren hemifumarate
T1520
Synonym: CGP 60536,SPP 100,CGP60536B
Target: RAAS, Autophagy
EMD638683
T6635
Synonym:
Target: SGK
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T8270 Deserpidine Harmonyl RAAS
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie...
TN1733 Hesperetin 7-O-glucoside Anti-infection , Antibacterial , HMG-CoA Reductase
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh...
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
TN1911 Marein transporter , Akt , HDAC , AMPK
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ...
T2939 Forskolin Coleonol,Colforsin FXR , Adenylyl cyclase , AChR , Autophagy
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...
T5S0106 Peimisine Ebeiensine RAAS , AChR
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...
TN1142 8-Oxocoptisine 8-Oxycoptisine Others
8-Oxocoptisine (8-Oxycoptisine) is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer
T6S0535 Pinoresinol diglucoside Pinoresinol Diglucopyranoside Glucosidase
1. Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound.
T19768 γ-Tocotrienol gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol Others
γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo.
T1035 Hesperidin Hesperetin 7-rutinoside,Cirantin Apoptosis , Reactive Oxygen Species , Endogenous Metabolite , Autophagy
Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
T0505 Methyldopa L-(-)-α-Methyldopa,MK-351 Dopamine Receptor , Adrenergic Receptor
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic.
T8061 Citronellal (±)-Citronellal Others
Citronellal ((±)-Citronellal) is a monoterpene predominantly formed by the secondary metabolism of plants, producing antithrombotic, antiplatelet, and antihypertensive activities.
T4S0792 Pinoresinol 4-O-β-D-glucopyranoside (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside Others
(+)-Pinoresinol-β-D-glucoside, also known as (+)-pinor, is a major active lignan furanoid found in Forsythia. It exhibits antioxidative, antihypertensive activities, and acts as an inhibitor of cyclic adenosine monophosp...
T6926 Palmitoylethanolamide Mackpeart DR 14V,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol Influenza Virus , Endogenous Metabolite , PPAR
Palmitoylethanolamide (Impulsin) is an endogenously fatty acid amide. It has a role as an anti-inflammatory drug, an antihypertensive agent, a neuroprotective agent and an anticonvulsant.Upon administration, palmitoyleth...
T1286 Vincamine Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval GPR , Others
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders.
T0883 Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed Beta Amyloid , GABA Receptor
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...
TN4883 Quinine sulfate dihydrate Others
Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...
T64744 Ovalbumins Endogenous Metabolite
Ovalbumins is the main protein found in egg whites. Ovalbumins have various biological activities such as antibacterial, anticancer, antihypertensive, antioxidant and immunomodulatory activities. Ovalbumins are the most ...
T0791 Reserpine Serpalan,Serpasil,Serpivite Others , Potassium Channel , MRP , Monoamine Transporter , Autophagy
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotoni...
T4S1637 Gamma-Mangostin Normangostin Others , 5-HT Receptor
1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin ...
TN6007 Serpentinine
Serpentinine may have antihypertensive effect.
TN1826 Kaempferol-4'-O-beta-D-glucopyranoside Others
Kaempferol-4'-O-beta-D-glucopyranoside is an antihypertensive agent.
T19911 Rescinnamine Anaprel,Apoterin S,Apoterin
Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
TN5645 Isomartynoside
Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity.
TN1367 Alismol Potassium Channel , Calcium Channel , PI3K
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for the prevention of anginal attacks.
TN1577 Dicentrine Others
Dicentrine, a selective α±(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities, it also has antinociception in different models of chemical pain.
TN4936 Salvisyrianone
Salvisyrianone is a diterpene isolated from Cryptomeria taiwanensis and S. syriacus with potential antihypertensive activity and antitumor activity.
TN4431 Leucosceptoside A RAAS , PKC
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows ...
T83562 (2R)-Flavanomarein
'(2R)-Flavanomarein, a major flavonoid from Coreopsis tinctoria Nutt, exhibits protective effects against diabetic nephropathy and possesses antioxidative, antidiabetic, antihypertensive, and anti-hyperlipidemic properti...
TN1681 Gentianine Others , TNF , transporter , PPAR
Gentianine is an effective Swertiamarin derivative, which has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, diuretic and other effects, and has the potential to be developed into a safe antihypertensive d...

Natural Products

Deserpidine
T8270
Synonym: Harmonyl
Target: RAAS
Hesperetin 7-O-glucoside
TN1733
Synonym:
Target: Anti-infection, Antibacterial, HMG-CoA Reductase
Flavanomarein
TN1644
Synonym:
Target: Others
Marein
TN1911
Synonym:
Target: transporter, Akt, HDAC, AMPK
Forskolin
T2939
Synonym: Coleonol,Colforsin
Target: FXR, Adenylyl cyclase, AChR, Autophagy
Peimisine
T5S0106
Synonym: Ebeiensine
Target: RAAS, AChR
8-Oxocoptisine
TN1142
Synonym: 8-Oxycoptisine
Target: Others
Pinoresinol diglucoside
T6S0535
Synonym: Pinoresinol Diglucopyranoside
Target: Glucosidase
γ-Tocotrienol
T19768
Synonym: gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol
Target: Others
Hesperidin
T1035
Synonym: Hesperetin 7-rutinoside,Cirantin
Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite, Autophagy
Methyldopa
T0505
Synonym: L-(-)-α-Methyldopa,MK-351
Target: Dopamine Receptor, Adrenergic Receptor
Citronellal
T8061
Synonym: (±)-Citronellal
Target: Others
Pinoresinol 4-O-β-D-glucopyranoside
T4S0792
Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside
Target: Others
Palmitoylethanolamide
T6926
Synonym: Mackpeart DR 14V,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol
Target: Influenza Virus, Endogenous Metabolite, PPAR
Vincamine
T1286
Synonym: Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval
Target: GPR, Others
Tramiprosate
T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed
Target: Beta Amyloid, GABA Receptor
Quinine sulfate dihydrate
TN4883
Synonym:
Target: Others
Ovalbumins
T64744
Synonym:
Target: Endogenous Metabolite
Reserpine
T0791
Synonym: Serpalan,Serpasil,Serpivite
Target: Others, Potassium Channel, MRP, Monoamine Transporter, Autophagy
gamma-Mangostin
T4S1637
Synonym: Normangostin
Target: Others, 5-HT Receptor
Serpentinine
TN6007
Synonym:
Target:
Kaempferol-4'-O-beta-D-glucopyranoside
TN1826
Synonym:
Target: Others
Rescinnamine
T19911
Synonym: Anaprel,Apoterin S,Apoterin
Target:
Isomartynoside
TN5645
Synonym:
Target:
Alismol
TN1367
Synonym:
Target: Potassium Channel, Calcium Channel, PI3K
Dicentrine
TN1577
Synonym:
Target: Others
Salvisyrianone
TN4936
Synonym:
Target:
Leucosceptoside A
TN4431
Synonym:
Target: RAAS, PKC
(2R)-Flavanomarein
T83562
Synonym:
Target:
Gentianine
TN1681
Synonym:
Target: Others, TNF, transporter, PPAR
Cat No. Product Name
L6820 Tobacco Monomer Library

750 compounds
A unique collection of 750 tobacco monomer compounds for high throughput screening and high content screening;
TargetMol