aki — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T64338	AKI603	AKI 603,AKI-603	Aurora Kinase
	AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l...		Aurora Kinase
T68332	AKI-001
	AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Phenotypic cellular...
T37596	Terevalefim		c-Met/HGFR
	Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.		c-Met/HGFR
T1439	Lacidipine	SN-305,GX-1048,GR-43659X	Apoptosis , Calcium Channel , Reactive Oxygen Species
	Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi...		Apoptosis , Calcium Channel , Reactive Oxygen Species
T2870	Matrine	Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.		Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
TQ0264	Nigakinone		Others
	Nigakinone, isolated from Kumu, is an alkaloid with the pharmacological activity.		Others
T76784	Tildrakizumab	MK 3222,SCH 900222	IL Receptor
	Tildrakizumab (SCH 900222) is a potent humanized monoclonal antibody against IL-23 (p19 subunit). Tildrakizumab targets single-stranded IL-23 with a Kd value of 136 pM. Tildrakizumab can be used to study psoriasis and ps...		IL Receptor
T28950	Terlakiren	CP 80794,CP-80,794	RAAS
	Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class.		RAAS
TP2075L	Bombinakinin M acetate	Bombinakinin M acetate(509151-65-9 free base)	Bradykinin Receptor
	Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin.		Bradykinin Receptor
T73695	Canakinumab	ACZ 885,Ilaris	IL Receptor
	Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody.Canakinumab has been shown to inhibit human and chorioallantoic monkey IL-1β, with IC50 values of 43.6 and 40.8 pM, respectively.Canakinumab...		IL Receptor
T76775	Fezakinumab	ILV 094	Interleukin
	Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related conditions such as psoriasis, rheumatoid arthritis and atopic dermat...		Interleukin
T4264	Takinib	EDHS-206	Apoptosis , MAPK
	Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).		Apoptosis , MAPK
T8813	Tetrakis (4-carboxyphenyl) porphyrin	TCPP,Tetracarboxyphenylporphine	Others
	Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover.Tetrakis (4-carboxyphenyl) porphyrin is a fabricated three dimensional Ru polymer complex. It can be grafted on SiO2/Nb2O5 substrate and subse...		Others
T66574	Sodium tetrakis (pentafluorophenyl)-borate
	sodium tetrakis (pentafluorophenyl)-borate is a useful organic compound for research related to life sciences and the catalog number is T66574.
T77034	Inbakicept	N-803
	Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity (ADCC). ...
T82882	Binetrakin
	Binetrakin (Interleukin 4 (human)) is a pleiotropic cytokine derived from T lymphocytes that influences multiple cell types, such as B cells and T cells, and promotes the differentiation of naive helper T cells (Th0 cell...
TP2225	Bombinakinin-GAP		Others
	Bioactive bradykinin-related peptide		Others
T75711	Contulakin G
	Contulakin G, an O-glycosylated invertebrate neurotensin, serves as a weaker agonist for the neurotensin receptor. Additionally, it is recognized as a potent antinociceptive agent [1] [2].
T37471	Makisterone A
	Makisterone A is an ecdysteroid that drives molting in insects. It binds the heterodimeric ecdysone receptor with nanomolar affinity.
T67239	Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II)
	Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) is a useful organic compound for research related to life sciences. The catalog number is T67239 and the CAS number is 909389-99-7.