Serine Protease

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site. They are found ubiquitously in both eukaryotes and prokaryotes.

Cat. No.	Product name	CAS No.	Purity
T13393	ZEN-3411	1952264-36-6	98%
T13393	ZEN-3411 is an inhibitor of BET(IC50s of 0.05, 0.05 and 0.06 μM for BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2), respectively). ZEN-3411 can be used to form PROTACs to...
T13412L	ZM223 hydrochloride (2031177-48-5 free base)	T13412L	98%
T13412L	ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
T13567	BCX 1470 methanesulfonate	217099-44-0	98%
T13567	BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respecti...
T13568	BCX 1470	217099-43-9	98%
T13568	BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.
T17288	ZD8321	182073-77-4	98%
T17288	ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).
T15285	FK706	144055-55-0	98%
T15285	FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM). FK706 also inhibits mouse neutrophil elastase and porcine ...
T22451	UK-371804 HCl	256476-36-5	98%
T22451	UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-fol...
T10254	AE-3763	291778-77-3	98%
T10254	AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).
T20992	MEGA-9	85261-19-4	98%
T20992	MEGA-9 solubilizes membrane protein and can be used as a nonionic detergent.
T13408	ZK824190	2254001-81-3	98%
T13408	ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 16...
T3359	Aprotinin	9087-70-1	98%
T3359	Aprotinin a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, ...
T3990	AA26-9	1312782-34-5	98%
T3990	AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase.
T8602	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE	13947-21-2	98%
T8602	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).
T5597	ZT-12-037-01	2328073-61-4	98%
T5597	Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).
T6564	Leupeptin Hemisulfate	103476-89-7	98%
T6564	Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
TN1372	Alpha-Amyrin	638-95-9	98%
TN1372	Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.
T25549	JCP174	126062-19-9	98%
T25549	JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.
T8802	2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-	80499-32-7	98%
T8802	Trypsin inhibitor (human urine urinastatin protein moiety)， as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or...
T12613L	BAY-85-8501	1161921-82-9	98%
T12613L	BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)
T6285	GSK-690693	937174-76-0	98%
T6285	GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.