thiol

Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.

Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.

Heptane-1-Thiol is a thiol widely used in biochemical experiments and drug synthesis research.

Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) is a chemoselective thiol probe for detection of electrophilic metabolites

5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL, with CAS No. 3004-42-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Amifostine thiol dihydrochloride (WR 1065) can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs.

Boc-Aminooxy-PEG3-thiol, a polyethylene glycol (PEG)-based PROTAC linker, is used in the synthesis of PROTACs[1].

m-PEG6-thiol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG8-thiol is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Thiol-PEG3-acid, a PEG-based linker for PROTACs, facilitates the connection of two essential ligands to form PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Thiol-PEG3-Boc, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Thiol-PEG3-phosphonic acid is a PEG-based linker compound used in PROTAC synthesis [1].

Thiol-PEG4-acid is a PEG-based linker for PROTACs, joining two essential ligands and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG4-Boc is a PEG-based linker for PROTACs that connects two key ligands, essential for forming PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Thiol-PEG6-alcohol is a PEG-based linker for PROTACs, joining two essential ligands for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG8-acid, a PEG-based linker for PROTACs, facilitates the conjugation of two essential ligands necessary for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

m-PEG-thiol (MW 10000) is a PEG-based linker for PROTACs that joins two critical ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 2000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 20000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 5000) is a PEG-based linker used in PROTACs, facilitating the conjugation of essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.