thiol

Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.

Heptane-1-Thiol is a thiol widely used in biochemical experiments and drug synthesis research.

Cysteine thiol probe (Methyl (4-bromobenzoyl)-L-cysteinate) is a chemoselective thiol probe for detection of electrophilic metabolites

5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL, with CAS No. 3004-42-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-(4-METHYLPHENYL)-1,3,4-OXADIAZOLE-2-THIOL provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Boc-Aminooxy-PEG3-thiol, a polyethylene glycol (PEG)-based PROTAC linker, is used in the synthesis of PROTACs[1].

m-PEG6-thiol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG8-thiol is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Thiol-PEG3-acid, a PEG-based linker for PROTACs, facilitates the connection of two essential ligands to form PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Thiol-PEG3-Boc, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Thiol-PEG3-phosphonic acid is a PEG-based linker compound used in PROTAC synthesis [1].

Thiol-PEG4-acid is a PEG-based linker for PROTACs, joining two essential ligands and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG4-Boc is a PEG-based linker for PROTACs that connects two key ligands, essential for forming PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Thiol-PEG6-alcohol is a PEG-based linker for PROTACs, joining two essential ligands for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG8-acid, a PEG-based linker for PROTACs, facilitates the conjugation of two essential ligands necessary for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

m-PEG-thiol (MW 10000) is a PEG-based linker for PROTACs that joins two critical ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 2000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 20000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 5000) is a PEG-based linker used in PROTACs, facilitating the conjugation of essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG12-Thiol is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

VH032 thiol (VHL ligand 6) is a VHL ligand that connects via a linker to the pan-BET inhibitor JQ1 to form a PROTAC[1] compound.