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Search Results for " parp-1 "

Targets

81

Compounds

11

Natural Products

1735

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T12365 PARP/PI3K-IN-1 PARP , PI3K
PARP/PI3K-IN-1 is a novel dual poly (ADP-ribose) polymerase (PARP) and phosphatidylinositol 3-kinase (PI3K) dual inhibitor with anticancer, antitumour and antiproliferative activities for the study of breast, pancreatic ...
T78182 PARP-1-IN-4 Others , PARP
PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.
T62281 PARP-1-IN-2 PARP
PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against the human lung adenocarcinoma epithelial cell line A549 in cel...
T40310 PARP/EZH2-IN-1 PARP/EZH2-IN-1
PARP/EZH2-IN-1 is a novel compound that functions as a dual inhibitor for both PARP (IC50 6.87 nM) and EZH2 (IC50 36.51 nM), showing promising potential for the treatment of triple-negative breast cancer with wild-type B...
T78157 PARP-1-IN-3 Apoptosis , PARP
PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inflammatory activity, induces apoptosis, and arrests the cell...
T12364 PARP-2-IN-1 Others
PARP-2-IN-1 is a potent and selective inhibitor of PARP-2(IC50 of 11.5 nM).
T72862 PARP-2/1-IN-2
PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentrat...
T6329 3-Aminobenzamide 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001 PARP
3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
T9610 PARP1-IN-5 dihydrochloride  PARP
PARP1-IN-5 dihydrochloride is an orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 dihydrochloride can be used for the research of cancer.
T61798 PARP-1-IN-1
PARP-1-IN-1 is a highly selective and orally active inhibitor of the enzyme PARP-1, with an IC50 value of 0.96 nM. It exhibits excellent tolerance and demonstrates significant activity in a single dose in the MDA-MB-436 ...
T6253 Talazoparib LT-673,BMN-673 PARP
Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
T79330 PARP-1-IN-13 PARP
PARP-1-IN-13 (Compound 19c) is a potent PARP-1 inhibitor with an IC50 of 26 nM, hindering DNA single-strand break repair and exacerbating DNA double-strand breaks. It induces apoptosis in cancer cells via the mitochondri...
T79647 VEGFR/PARP-IN-1 PARP
VEGFR/PARP-IN-1 (Compound 14b) is a dual inhibitor of VEGFR and PARP with IC50 values of 191 nM and 60.9 nM, respectively. It impairs DNA damage repair pathways, promotes apoptosis, and halts cells in the G2/M phase. Thi...
T8478 SC-43 Apoptosis , Phosphatase , STAT
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
T62508 PARP-1/2-IN-1
PARP-1-/2-IN-1 is a potent inhibitor of PARP-1 (IC50: 0.51 nM) and PARP-2 (IC50: 23.11 nM).
T61962 PARP-1/HDAC-IN-1
PARP-1/HDAC-IN-1 is an effective dual inhibitor of PARP-1/HDAC6, with IC50 of 68.90 nM and 510 nM respectively. PARP-1/HDAC-IN-1 has anti-cancer, anti-migration and anti-angiogenesis activities.
T16807 Rucaparib monocamsylate Rucaparib Camsylate PARP
Rucaparib monocamsylate (Rucaparib Camsylate) is a PARP inhibitor (PARP1,Ki of 1.4 nM). Rucaparib Camsylate also displays binding affinity to eight other PARP domains.
T74173 PROTAC PARP/EGFR ligand 1
PROTAC PARP/EGFR ligand 1 is a potent compound utilized in the creation of dual PARP-EGFR degraders through Proteolytic Targeting Chimera (PROTAC) technology [1].
T78787 PARP-1/2-IN-2 PARP
PARP-1/2-IN-2-IN-1 (Compound 12e) effectively inhibits PARP1/2 and CDK12 with IC 50 values of 34 nM, 30 nM, and 285 nM respectively, impairing DNA damage repair and inducing cell cycle arrest and apoptosis. This compound...
T9891 PARP1-IN-8  N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide PARP
PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) is an effective inhibito of PARP1 (IC50 = 97 nM).
T4463 Rucaparib AG-14447,PF-01367338,AG014699 PARP
Rucaparib (PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP.
T13845 PROTAC PARP1 degrader Others
PROTAC PARP1 degrader is a degrader of PARP1 based on the PROTAC technology. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line (IC50 of 6.12 μM).
T39139 PARP1-IN-6 PARP1-IN-6
PARP1-IN-6, a dual-function inhibitor, targets both tubulin and PARP-1, demonstrating inhibitory concentration (IC50) values of 0.94 μM for tubulin and 0.48 μM for PARP-1.
T6127 Rucaparib Phosphate AG-014699 phosphate,PF-01367338,AG-014699,PF-01367338 phosphate PARP
Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP (Ki: 1.4 nM for PARP1) that is used in clinical therapy to sensitize cancer cells to chemotherapy.
T12617L (R)​-​CR8 (R)-CR8,(R)-Isomer,CR8 Apoptosis , CDK
(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.
T4472 NMS-P118 PARP
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
T72437 PARP1/2/TNKS1/2-IN-1 Apoptosis , PARP , Wnt/beta-catenin
PARP1/2/TNKS1/2-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1 and TNKS2.PARP1/2/TNKS1/2-IN-1 has potential anti-tumor activity and induces apoptosis.
T22749 DR2313 DR 2313 PARP
DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.
T11143 EB-47 PARP
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC...
T67945 WAY-620473 PARP
WAY-620473 is a potent PARP-1 inhibitor with antitumor activity and alters eukaryotic lifespan.
T1807 JW 55 JW55 PARP , Wnt/beta-catenin
JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2).
T1772 MDK83190 Apoptosis Activator 2 Apoptosis , Caspase
MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .
T6181 UPF 1069 PARP
UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.
T6768 AZ6102 PARP , Wnt/beta-catenin
AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.
T72553 ARTD10/PARP10-IN-1 PARP
ARTD10/PARP10-IN-1 is a potent PARP inhibitor of the mono-ADP ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly ADP-ribose polymerase-1 (ARTD1/PARP1), with potential anticancer and antitumour activit...
T6339 AG14361 AG 14361,AG-14361 PARP
AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).
T3015 Olaparib AZD2281,KU0059436 Mitophagy , PARP , Autophagy
Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and m...
T10896L CSRM617 hydrochloride CSRM617 hydrochloride(787504-88-5 Free base) Apoptosis , Others , Androgen Receptor
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSR...
T22264 AZ9482 PARP
AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.
T60039 KSQ-4279 USP1-IN-1 PARP , DUB
KSQ-4279 (USP1-IN-1) is an inhibitor of USP1 and PARP.KSQ-4279 has anticancer activity and is used in the study of non-small cell lung cancer, osteosarcoma, ovarian, breast, glioblastoma, bladder, uterine and pancreatic ...
T3157 COH29 RNR Inhibitor COH29 DNA/RNA Synthesis
COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and inhibitor of the human ribonucleotide reductase (RNR), with potential antineoplastic activity. Upon oral administration, the RNR i...
T81543 PARP1-IN-17 PARP
PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity for PARP-2 (IC50=32.58 nM ) and induces apoptosis. It exhibits robust anti-proliferative activity [1].
T36251 DP-C-4
DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [...
T13333 WD2000-012547 Others
WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).
T79853 Lerzeparib PARP
Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].
T63065 Rucaparib tartrate
Rucaparib (AG014699) tartrate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) and acts on PARP-1 (Ki: 1.4 nM).Rucaparib tartrate is a hexose hexaphosphate dehydrogenase (H6PD) inhibitor. Rucapa...
T75344 NCT-TFP
NCT-TFP is PARP probe used to identifying Poly(ADP-ribose) polymerases (PARP) inhibitors[1].
T22756 EB-47 dihydrochloride EB 47 Others
EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).
T61335 Rucaparib hydrochloride
Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydr...
T64289 Rucaparib camsylate
Rucaparib (AG014699) camsylate is an orally active inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki=1.4 nM for PARP-1. Rucaparib camsylate is an inhibitor of hexose hexaphosphate dehydrogenase (H6PD). Ruc...

Compounds

PARP/PI3K-IN-1
T12365
Synonym:
Target: PARP, PI3K
PARP-1-IN-4
T78182
Synonym:
Target: Others, PARP
PARP-1-IN-2
T62281
Synonym:
Target: PARP
PARP/EZH2-IN-1
T40310
Synonym: PARP/EZH2-IN-1
Target:
PARP-1-IN-3
T78157
Synonym:
Target: Apoptosis, PARP
PARP-2-IN-1
T12364
Synonym:
Target: Others
PARP-2/1-IN-2
T72862
Synonym:
Target:
3-Aminobenzamide
T6329
Synonym: 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001
Target: PARP
PARP1-IN-5 dihydrochloride 
T9610
Synonym:
Target: PARP
PARP-1-IN-1
T61798
Synonym:
Target:
Talazoparib
T6253
Synonym: LT-673,BMN-673
Target: PARP
PARP-1-IN-13
T79330
Synonym:
Target: PARP
VEGFR/PARP-IN-1
T79647
Synonym:
Target: PARP
SC-43
T8478
Synonym:
Target: Apoptosis, Phosphatase, STAT
PARP-1/2-IN-1
T62508
Synonym:
Target:
PARP-1/HDAC-IN-1
T61962
Synonym:
Target:
Rucaparib monocamsylate
T16807
Synonym: Rucaparib Camsylate
Target: PARP
PROTAC PARP/EGFR ligand 1
T74173
Synonym:
Target:
PARP-1/2-IN-2
T78787
Synonym:
Target: PARP
PARP1-IN-8 
T9891
Synonym: N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide
Target: PARP
Rucaparib
T4463
Synonym: AG-14447,PF-01367338,AG014699
Target: PARP
PROTAC PARP1 degrader
T13845
Synonym:
Target: Others
PARP1-IN-6
T39139
Synonym: PARP1-IN-6
Target:
Rucaparib Phosphate
T6127
Synonym: AG-014699 phosphate,PF-01367338,AG-014699,PF-01367338 phosphate
Target: PARP
(R)​-​CR8
T12617L
Synonym: (R)-CR8,(R)-Isomer,CR8
Target: Apoptosis, CDK
NMS-P118
T4472
Synonym:
Target: PARP
PARP1/2/TNKS1/2-IN-1
T72437
Synonym:
Target: Apoptosis, PARP, Wnt/beta-catenin
DR2313
T22749
Synonym: DR 2313
Target: PARP
EB-47
T11143
Synonym:
Target: PARP
WAY-620473
T67945
Synonym:
Target: PARP
JW 55
T1807
Synonym: JW55
Target: PARP, Wnt/beta-catenin
MDK83190
T1772
Synonym: Apoptosis Activator 2
Target: Apoptosis, Caspase
UPF 1069
T6181
Synonym:
Target: PARP
AZ6102
T6768
Synonym:
Target: PARP, Wnt/beta-catenin
ARTD10/PARP10-IN-1
T72553
Synonym:
Target: PARP
AG14361
T6339
Synonym: AG 14361,AG-14361
Target: PARP
Olaparib
T3015
Synonym: AZD2281,KU0059436
Target: Mitophagy, PARP, Autophagy
CSRM617 hydrochloride
T10896L
Synonym: CSRM617 hydrochloride(787504-88-5 Free base)
Target: Apoptosis, Others, Androgen Receptor
AZ9482
T22264
Synonym:
Target: PARP
KSQ-4279
T60039
Synonym: USP1-IN-1
Target: PARP, DUB
COH29
T3157
Synonym: RNR Inhibitor COH29
Target: DNA/RNA Synthesis
PARP1-IN-17
T81543
Synonym:
Target: PARP
DP-C-4
T36251
Synonym:
Target:
WD2000-012547
T13333
Synonym:
Target: Others
Lerzeparib
T79853
Synonym:
Target: PARP
Rucaparib tartrate
T63065
Synonym:
Target:
NCT-TFP
T75344
Synonym:
Target:
EB-47 dihydrochloride
T22756
Synonym: EB 47
Target: Others
Rucaparib hydrochloride
T61335
Synonym:
Target:
Rucaparib camsylate
T64289
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T8150 Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide PARP , Endogenous Metabolite
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
T2851 Daphnetin 7,8-Dihydroxycoumarin,Daphnetol EGFR , PKA , PKC , Parasite , Autophagy
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...
T4085 Paris saponin VII Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T3S1471 Cucurbitacin IIA Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA Apoptosis , Survivin
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ...
T6S2391 L-Chicoric Acid (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,dicaffeoyltartaric acid Others , HIV Protease
L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity in vitro and in vivo and antiviral acitivy. L-Chicoric acid may ...
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T4973 Paraxanthine 1,7-DIMETHYLXANTHINE Endogenous Metabolite
Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T5S1805 5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One Others , Virus Protease , PARP , Caspase , Nrf2
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...
T24638 Picrasidine M
Picrasidine M is a PARP-1 inhibitor.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01188 PARP Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8.
TMPY-02465 PARP Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
PARP Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 115 kDa and the accession number is Q921K2.
TMPY-02831 Caspase-7 Protein, Human, Recombinant (His) Human E. coli
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-01968 CD32A Protein, Human, Recombinant (167 His, His) Human HEK293 Cells
CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-04824 CTLA-4 Protein, Human, Recombinant Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-04632 IL-15 Protein, Human, Recombinant Human E. coli
IL-15 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.8 kDa and the accession number is P40933-1.
TMPY-00414 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) Human HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
TMPY-04529 EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) Human Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-05201 Siglec-2/CD22 Protein, Human, Recombinant Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1.
TMPY-03782 Albumin Protein, Human, Recombinant Human P. pastoris (Yeast)
Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
TMPY-03956 Fas Ligand Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-01578 CD166/ALCAM Protein, Human, Recombinant (His) Human HEK293 Cells
CD166/ALCAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is Q13740-1.
TMPY-05277 IL-4R Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-4R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P24394-1.
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His) Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01076 Gp130/IL6ST Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
TMPY-00756 FGF-1 Protein, Human, Recombinant Human E. coli
FGF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P05230-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-05566 Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1.
TMPY-00322 DEC-205 Protein, Human, Recombinant (His) Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-02512 Alpha-Synuclein Protein, Human, Recombinant Human E. coli
Alpha-Synuclein Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.5 kDa and the accession number is P37840-1.
TMPY-05030 PCDH7 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cance...
TMPY-06076 LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-00742 EGFR Protein, Human, Recombinant (His) Human HEK293 Cells
EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPY-01964 CD16a Protein, Human, Recombinant (F176V, His) Human HEK293 Cells
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPY-00694 Carbonic Anhydrase 12 Protein, Human, Recombinant (His) Human HEK293 Cells
Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1.
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His) Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPY-04343 PD-L1 Protein, Human, Recombinant (His) Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1.
TMPY-04153 RNF43 Protein, Human, Recombinant (His) Human HEK293 Cells
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-03273 IL-18 Protein, Mouse, Recombinant Mouse E. coli
IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1.
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1.
TMPY-05593 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S) Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-00686 Complement C2 Protein, Human, Recombinant (His) Human HEK293 Cells
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1.
TMPY-05827 PD-L2 Protein, Human, Recombinant (mFc) Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1.
TMPY-05840 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1.
TMPY-01862 IL-4 Protein, Human, Recombinant Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-02591 SDF-1 Protein, Human, Recombinant Human E. coli
SDF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.6 kDa and the accession number is P48061-1.
TMPY-04104 LIF Protein, Human, Recombinant Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-00464 M-CSF/CSF1 Protein, Mouse, Recombinant Mouse HEK293 Cells
M-CSF/CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1.
TMPY-04261 CD64 Protein, Human, Recombinant (His) Human HEK293 Cells
CD64 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32 kDa and the accession number is P12314-1.
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant...
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PARP Protein, Human, Recombinant (His)
TMPY-01188
Species: Human
Expression System: Baculovirus Insect Cells
PARP Protein, Mouse, Recombinant (His)
TMPY-02465
Species: Mouse
Expression System: Baculovirus Insect Cells
Caspase-7 Protein, Human, Recombinant (His)
TMPY-02831
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293 Cells
CD32A Protein, Human, Recombinant (167 His, His)
TMPY-01968
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant
TMPY-04824
Species: Human
Expression System: HEK293 Cells
IL-15 Protein, Human, Recombinant
TMPY-04632
Species: Human
Expression System: E. coli
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)
TMPY-00414
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
TMPY-04529
Species: Human
Expression System: Baculovirus Insect Cells
Siglec-2/CD22 Protein, Human, Recombinant
TMPY-05201
Species: Human
Expression System: HEK293 Cells
Albumin Protein, Human, Recombinant
TMPY-03782
Species: Human
Expression System: P. pastoris (Yeast)
Fas Ligand Protein, Human, Recombinant (His)
TMPY-03956
Species: Human
Expression System: P. pastoris (Yeast)
CD166/ALCAM Protein, Human, Recombinant (His)
TMPY-01578
Species: Human
Expression System: HEK293 Cells
IL-4R Protein, Human, Recombinant (hFc)
TMPY-05277
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
TMPY-01920
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
TMPY-05220
Species: Human
Expression System: HEK293 Cells
gp130/IL6ST Protein, Human, Recombinant (His & hFc)
TMPY-01076
Species: Human
Expression System: HEK293 Cells
FGF-1 Protein, Human, Recombinant
TMPY-00756
Species: Human
Expression System: E. coli
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
TMPY-06418
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
TMPY-05566
Species: Human
Expression System: HEK293 Cells
DEC-205 Protein, Human, Recombinant (His)
TMPY-00322
Species: Human
Expression System: HEK293 Cells
Alpha-Synuclein Protein, Human, Recombinant
TMPY-02512
Species: Human
Expression System: E. coli
PCDH7 Protein, Human, Recombinant (His)
TMPY-05030
Species: Human
Expression System: Baculovirus Insect Cells
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
TMPY-06076
Species: Human
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
TMPY-06873
Species: Human
Expression System: E. coli
EGFR Protein, Human, Recombinant (His)
TMPY-00742
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
TMPY-04939
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
TMPY-01209
Species: Human
Expression System: HEK293 Cells
CD16a Protein, Human, Recombinant (F176V, His)
TMPY-01964
Species: Human
Expression System: HEK293 Cells
Carbonic Anhydrase 12 Protein, Human, Recombinant (His)
TMPY-00694
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
TMPY-03967
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06074
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant (His)
TMPY-04343
Species: Human
Expression System: HEK293 Cells
RNF43 Protein, Human, Recombinant (His)
TMPY-04153
Species: Human
Expression System: HEK293 Cells
IL-18 Protein, Mouse, Recombinant
TMPY-03273
Species: Mouse
Expression System: E. coli
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
TMPY-01410
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05593
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
TMPY-00820
Species: Human
Expression System: HEK293 Cells
Complement C2 Protein, Human, Recombinant (His)
TMPY-00686
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc)
TMPY-05827
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)
TMPY-05840
Species: Cynomolgus
Expression System: HEK293 Cells
IL-4 Protein, Human, Recombinant
TMPY-01862
Species: Human
Expression System: E. coli
SDF-1 Protein, Human, Recombinant
TMPY-02591
Species: Human
Expression System: E. coli
LIF Protein, Human, Recombinant
TMPY-04104
Species: Human
Expression System: HEK293 Cells
M-CSF/CSF1 Protein, Mouse, Recombinant
TMPY-00464
Species: Mouse
Expression System: HEK293 Cells
CD64 Protein, Human, Recombinant (His)
TMPY-04261
Species: Human
Expression System: HEK293 Cells
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
TMPY-02779
Species: Human
Expression System: Baculovirus Insect Cells
Cat No. Product Name
L2191 Anti-Breast Cancer Compound Library

1939 compounds
A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study;
TargetMol